|
Bordet-Wassermann Test
The Wassermann test or Wassermann reaction (WR) is an antibody test for syphilis, named after the bacteriologist August Paul von Wassermann, based on complement fixation. It was the first blood test for syphilis and the first in the nontreponemal test (NTT) category. Newer NTTs, such as the RPR and VDRL tests, have mostly replaced it. Method A sample of blood or cerebrospinal fluid is taken and introduced to the antigen – cardiolipin extracted from bovine muscle or heart. Syphilis non-specific antibodies ( reagin, see RPR) react with the lipid – the Wassermann reaction of antiphospholipid antibodies (APAs). The intensity of the reaction (classed 1, 2, 3, or 4) indicates the severity of the condition. Uncertainty The reaction is not specific to syphilis and will produce a positive reaction to other diseases, including systemic lupus erythematosus, malaria, and tuberculosis. It is possible for an infected individual to produce no reaction and for a successfully treated indi ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Exploitation Film
An exploitation film is a film that tries to succeed financially by exploiting current trends, niche genres, or lurid content. Exploitation films are generally low-quality "B movies", though some set trends, attract critical attention, become historically important, and even gain a cult following. History Exploitation films may feature suggestive or explicit sex, sensational violence, drug use, nudity, gore, destruction, rebellion, mayhem, and the bizarre. Such films were first seen in their modern form in the early 1920s, but they were popularized in the 60s and 70s with the general relaxing of censorship and cinematic taboos in the U.S. and Europe. An early example, the 1933 film Ecstasy, included nude scenes featuring the Austrian actress Hedy Lamarr. The film proved popular at the box office but caused concern for the American cinema trade association, the MPPDA. Hildegard Esper and Dwain Esper are husband and wife film directors and producers who made some of the most ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Systemic Lupus Erythematosus
Lupus, technically known as systemic lupus erythematosus (SLE), is an autoimmune disease in which the body's immune system mistakenly attacks healthy tissue in many parts of the body. Symptoms vary among people and may be mild to severe. Common symptoms include painful and swollen joints, fever, chest pain, hair loss, mouth ulcers, swollen lymph nodes, feeling tired, and a red rash which is most commonly on the face. Often there are periods of illness, called flares, and periods of remission during which there are few symptoms. The cause of SLE is not clear. It is thought to involve a mixture of genetics combined with environmental factors. Among identical twins, if one is affected there is a 24% chance the other one will also develop the disease. Female sex hormones, sunlight, smoking, vitamin D deficiency, and certain infections are also believed to increase a person's risk. The mechanism involves an immune response by autoantibodies against a person's own tissues. T ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Syphilis
Syphilis () is a sexually transmitted infection caused by the bacterium ''Treponema pallidum'' subspecies ''pallidum''. The signs and symptoms of syphilis vary depending in which of the four stages it presents (primary, secondary, latent, and tertiary). The primary stage classically presents with a single chancre (a firm, painless, non-itchy skin ulceration usually between 1 cm and 2 cm in diameter) though there may be multiple sores. In secondary syphilis, a diffuse rash occurs, which frequently involves the palms of the hands and soles of the feet. There may also be sores in the mouth or vagina. In latent syphilis, which can last for years, there are few or no symptoms. In tertiary syphilis, there are gummas (soft, non-cancerous growths), neurological problems, or heart symptoms. Syphilis has been known as "the great imitator" as it may cause symptoms similar to many other diseases. Syphilis is most commonly spread through sexual activity. It may also be transmi ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Infectious Disease Blood Tests
An infection is the invasion of tissues by pathogens, their multiplication, and the reaction of host tissues to the infectious agent and the toxins they produce. An infectious disease, also known as a transmissible disease or communicable disease, is an illness resulting from an infection. Infections can be caused by a wide range of pathogens, most prominently bacteria and viruses. Hosts can fight infections using their immune system. Mammalian hosts react to infections with an innate response, often involving inflammation, followed by an adaptive response. Specific medications used to treat infections include antibiotics, antivirals, antifungals, antiprotozoals, and antihelminthics. Infectious diseases resulted in 9.2 million deaths in 2013 (about 17% of all deaths). The branch of medicine that focuses on infections is referred to as infectious disease. Types Infections are caused by infectious agents (pathogens) including: * Bacteria (e.g. ''Mycobacterium tuberculosis'', ' ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Autoimmune Disease
An autoimmune disease is a condition arising from an abnormal immune response to a functioning body part. At least 80 types of autoimmune diseases have been identified, with some evidence suggesting that there may be more than 100 types. Nearly any body part can be involved. Common symptoms can be diverse and transient, ranging from mild to severe, and generally include low grade fever and feeling tired. The cause is unknown. Some autoimmune diseases such as lupus run in families, and certain cases may be triggered by infections or other environmental factors. Some common diseases that are generally considered autoimmune include celiac disease, diabetes mellitus type 1, graves' disease, inflammatory bowel disease, multiple sclerosis, alopecia areata, addison’s disease, pernicious anemia, psoriasis, rheumatoid arthritis, and systemic lupus erythematosus. The diagnosis can be difficult to determine. Treatment depends on the type and severity of the condition. Nonsteroidal ant ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Flocculation
Flocculation, in the field of chemistry, is a process by which colloidal particles come out of suspension to sediment under the form of floc or flake, either spontaneously or due to the addition of a clarifying agent. The action differs from precipitation in that, prior to flocculation, colloids are merely suspended, under the form of a stable dispersion (where the internal phase (solid) is dispersed throughout the external phase (fluid) through mechanical agitation) and are not truly dissolved in solution. Coagulation and flocculation are important processes in water treatment with coagulation aimed to destabilize and aggregate particles through chemical interactions between the coagulant and colloids, and flocculation to sediment the destabilized particles by causing their aggregation into floc. Term definition According to the IUPAC definition, flocculation is "a process of contact and adhesion whereby the particles of a dispersion form larger-size clusters". Flocculation ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
VDRL
The Venereal Disease Research Laboratory test (VDRL) is a blood test for syphilis and related non-venereal treponematoses that was developed by the eponymous lab. The VDRL test is used to screen for syphilis (it has high sensitivity), whereas other, more specific tests are used to diagnose the disease. History The VDRL type test was invented before World War I, with its first iteration being that developed by August Paul von Wasserman with the aid of Albert Neisser in 1906. The VDRL test, as it is largely still done today, was developed in 1946 by Harris, Rosenberg, and Riedel. The lab was renamed to the Treponemal Pathogenesis and Immunology Branch of the United States Public Health Service. Mechanism The VDRL is a nontreponemal serological screening for syphilis that is also used to assess response to therapy, to detect central nervous system involvement, and as an aid in the diagnosis of congenital syphilis. The basis of the test is that an antibody produced by a patient with ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Kolmer Test
Kolmer is a German-language surname from a status name originally denoting a yeoman according to Kulm law. It may refer to: * Eva Schmidt-Kolmer (1913–1991), Austrian-German physician *Felix Kolmer Felix Kolmer (3 May 1922 – 5 August 2022) was a Czech physicist of Jewish origin, specialising in the field of acoustics. During the Second World War, he was active in the Czech Resistance. Early life Kolmer was born in Prague in 1922 to ... (1922–2022), Czech physicist, specialising in the field of acoustics References {{surname, Kolmer German-language surnames Surnames from status names ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Kahn Test
Kahn is a surname of German origin. ''Kahn'' means "small boat", in German. It is also a Germanized form of the Jewish surname Cohen, another variant of which is ''Cahn''. in the People with the personal name Kahn * Kahn Fotuali'i (born 1982), New Zealand rugby-union player of Samoan origin * (1861–1938), Punjabi Sikh scholar, writer, anthologist, lexicographer, and encyclopedistPeople with the surname Kahn *[...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Octave Gengou
Octave Gengou (27 February 1875, Ouffet – 25 April 1957, Brussels) was a Belgian bacteriologist. He researched with Jules Bordet the ''Bordetella pertussis'' bacteria. Biography At the age of 22, he obtained his doctorate at the University of Liège, later being named as deputy director at the Pasteur Institute of Brabant. In 1945, he became professor emeritus at the University of Brussels.ARMB; Royal Academy of Medicine of Belgium biographical information Gengou worked at the Belgium in . With |
Jules Jean Baptiste Vincent Bordet
Jules Jean Baptiste Vincent Bordet (; 13 June 1870 – 6 April 1961) was a Belgian immunologist and microbiologist. The bacterial genus ''Bordetella'' is named after him. The Nobel Prize in Physiology or Medicine was awarded to him in 1919 for his discoveries relating to immunity. Education and early life Bordet was born at Soignies, Belgium. He graduated as Doctor of Medicine from the Free University of Brussels in 1892 and began his work at the Pasteur Institute in Paris in 1894, in the laboratory of Elie Metchnikoff, who had just discovered phagocytosis of bacteria by white blood cells, an expression of cellular immunity. Career In 1895 Bordet made his discovery that the bacteriolytic effect of acquired specific antibody is significantly enhanced ''in vivo'' by the presence of innate serum components which he termed alexine (but which are now known as complement). Four years later, in 1899, he described a similar destructive process involving complement, "hemolysis", in wh ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Robert Koch Institute For Infectious Diseases
The Robert Koch Institute (RKI) is a German federal government agency and research institute responsible for disease control and prevention. It is located in Berlin and Wernigerode. As an upper federal agency, it is subordinate to the Federal Ministry of Health. It was founded in 1891 and is named for its founding director, the founder of modern bacteriology and Nobel laureate Robert Koch. Tasks The Robert Koch Institute monitors public health. Its core tasks include the detection, prevention and combatting of infectious diseases and non-communicable diseases in Germany. The institute advises the specialist public and government, e.g. on preventing and tackling infectious disease outbreaks such as the COVID-19 pandemic, the swine flu pandemic in 2009 and the 2011 Germany E. coli O104:H4 outbreak, EHEC O104:H4 outbreak in 2011. The institute is also in charge of health monitoring and health reporting in Germany, covering non-communicable diseases: in large monitoring studies ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
