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Björn Sigurðsson
Dr. Björn Sigurðsson (1913–1959) was the first director of Keldur - the Institute for Experimental Pathology, University of Iceland. Björn died at an early age while having been the director of Keldur for only about ten years. In his short life, he made many developments in research in the fields of pathology, bacteriology, virology, immunology and epidemiology. Björn became a world-renowned scientist because of his research on infectious diseases caused by slow viruses. This group of viruses was given the name, Lentivirus, in honor of the work of Björn Sigurðsson. The slow virus concept was first introduced by Björn Sigurðsson and he and his co-workers made pioneering studies on slow diseases in sheep including mæði, visna and scrapie. Mæði is a slowly progressive interstitial pneumonia of adult sheep while visna is a slow, progressive encephalomyelitis Encephalomyelitis is inflammation of the brain and spinal cord. Various types of encephalomyelitis incl ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Keldur Institute
Keldur – Institute for Experimental Pathology, University of Iceland is a university institution at Keldur near Reykjavik. It is connected to the Faculty of Medicine but has its own board and independent finances. The operations at Keldur are very diverse. Many scientific methods are used in basic research and services, for example pathology, microbiology, immunology, parasitology, biochemistry and molecular biology. History and function The Institute at Keldur was established in the autumn of 1948. It is under the supervision of theMinistry of Education and Culture The first director of Keldur was Björn Sigurðsson,Guðmundur Pétursson. „Hver var Björn Sigurðsson og hvert var hans framlag til vísinda?“Vísindavefurinn 14.1.2011.(Skoðað 19.1.2011). physician. The Rockefeller Foundation provided financial support to build and equip the Institute at Keldur but its original role was to respond to an epidemic in sheep, the Maedi Visna Virus, that resulted from conta ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Visna Virus
''Visna-maedi virus'' (also known as ''Visna virus'', ''Maedi-visna virus'' and ''Ovine lentivirus'') from the genus ''Lentivirus'' and subfamily ''Orthoretrovirinae'', is a retrovirus that causes encephalitis and chronic pneumonitis in sheep. It is known as visna when found in the brain, and maedi when infecting the lungs. Lifelong, persistent infections in sheep occur in the lungs, lymph nodes, spleen, joints, central nervous system, and mammary glands; The condition is sometimes known as ovine progressive pneumonia (OPP), particularly in the United States, or Montana sheep disease. White blood cells of the monocyte/macrophage lineage are the main target of the virus. Viral infection First described in 1954 by Bjorn Sigurdsson in Iceland, Maedi-visna virus was the first lentivirus to be isolated and characterized, accomplished in 1957 by Sigurdsson. ''Maedi'' ( Icelandic ' 'dyspnoea') and ''visna'' (Icelandic ' 'wasting' or 'shrinking' of the spinal cord) refer to endemic shee ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
1959 Deaths
Events January * January 1 - Cuba: Fulgencio Batista flees Havana when the forces of Fidel Castro advance. * January 2 - Lunar probe Luna 1 was the first man-made object to attain escape velocity from Earth. It reached the vicinity of Earth's Moon, and was also the first spacecraft to be placed in heliocentric orbit. * January 3 ** The three southernmost atolls of the Maldive Islands, Maldive archipelago (Addu Atoll, Huvadhu Atoll and Fuvahmulah island) United Suvadive Republic, declare independence. ** Alaska is admitted as the 49th U.S. state. * January 4 ** In Cuba, rebel troops led by Che Guevara and Camilo Cienfuegos enter the city of Havana. ** Léopoldville riots: At least 49 people are killed during clashes between the police and participants of a meeting of the ABAKO Party in Kinshasa, Léopoldville in the Belgian Congo. * January 6 ** Fidel Castro arrives in Havana. ** The International Maritime Organization is inaugurated. * January 7 – The United States reco ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
1913 Births
Events January * January 5 – First Balkan War: Battle of Lemnos – Greek admiral Pavlos Kountouriotis forces the Turkish fleet to retreat to its base within the Dardanelles, from which it will not venture for the rest of the war. * January 13 – Edward Carson founds the (first) Ulster Volunteer Force, by unifying several existing loyalist militias to resist home rule for Ireland. * January 23 – 1913 Ottoman coup d'état: Ismail Enver comes to power. * January – Stalin (whose first article using this name is published this month) travels to Vienna to carry out research. Until he leaves on February 16 the city is home simultaneously to him, Hitler, Trotsky and Tito alongside Berg, Freud and Jung and Ludwig and Paul Wittgenstein. February * February 1 – New York City's Grand Central Terminal, having been rebuilt, reopens as the world's largest railroad station. * February 3 – The 16th Amendment to the United S ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Retrovirus
A retrovirus is a type of virus that inserts a DNA copy of its RNA genome into the DNA of a host cell that it invades, thus changing the genome of that cell. Once inside the host cell's cytoplasm, the virus uses its own reverse transcriptase enzyme to produce DNA from its RNA genome, the reverse of the usual pattern, thus ''retro'' (backwards). The new DNA is then incorporated into the host cell genome by an integrase enzyme, at which point the retroviral DNA is referred to as a provirus. The host cell then treats the viral DNA as part of its own genome, transcribing and translating the viral genes along with the cell's own genes, producing the proteins required to assemble new copies of the virus. Although retroviruses have different subfamilies, they have three basic groups: the oncoretroviruses (oncogenic retroviruses), the lentiviruses (slow retroviruses) and the spumaviruses (foamy viruses). The oncoretroviruses are able to cause cancer in some species, the lentiviru ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Encephalomyelitis
Encephalomyelitis is inflammation of the brain and spinal cord. Various types of encephalomyelitis include: * ''Acute disseminated encephalomyelitis'' or ''postinfectious encephalomyelitis'', a demyelinating disease of the brain and spinal cord, possibly triggered by viral infection. * ''Encephalomyelitis disseminata'', a synonym for multiple sclerosis. * ''AntiMOG associated encephalomyelitis'', one of the underlying conditions for the phenotype neuromyelitis optica and in general all the spectrum of MOG autoantibody-associated demyelinating diseases. * '' Eastern equine encephalitis'', ''Japanese encephalitis'', ''Venezuelan equine encephalitis'', and ''Western equine encephalitis'': a group of viral illnesses that can affect horses and humans; collectively termed ''Equine encephalitis''. * ''Experimental autoimmune encephalomyelitis'' (EAE), an animal model of brain inflammation. * Progressive encephalomyelitis with rigidity and myoclonus (PERM) – A kind of stiff person synd ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Visna Virus
''Visna-maedi virus'' (also known as ''Visna virus'', ''Maedi-visna virus'' and ''Ovine lentivirus'') from the genus ''Lentivirus'' and subfamily ''Orthoretrovirinae'', is a retrovirus that causes encephalitis and chronic pneumonitis in sheep. It is known as visna when found in the brain, and maedi when infecting the lungs. Lifelong, persistent infections in sheep occur in the lungs, lymph nodes, spleen, joints, central nervous system, and mammary glands; The condition is sometimes known as ovine progressive pneumonia (OPP), particularly in the United States, or Montana sheep disease. White blood cells of the monocyte/macrophage lineage are the main target of the virus. Viral infection First described in 1954 by Bjorn Sigurdsson in Iceland, Maedi-visna virus was the first lentivirus to be isolated and characterized, accomplished in 1957 by Sigurdsson. ''Maedi'' ( Icelandic ' 'dyspnoea') and ''visna'' (Icelandic ' 'wasting' or 'shrinking' of the spinal cord) refer to endemic shee ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Interstitial Pneumonia
Interstitial lung disease (ILD), or diffuse parenchymal lung disease (DPLD), is a group of respiratory diseases affecting the interstitium (the tissue and space around the alveoli (air sacs)) of the lungs. It concerns alveolar epithelium, pulmonary capillary endothelium, basement membrane, and perivascular and perilymphatic tissues. It may occur when an injury to the lungs triggers an abnormal healing response. Ordinarily, the body generates just the right amount of tissue to repair damage, but in interstitial lung disease, the repair process is disrupted, and the tissue around the air sacs (alveoli) becomes scarred and thickened. This makes it more difficult for oxygen to pass into the bloodstream. The disease presents itself with the following symptoms: shortness of breath, nonproductive coughing, fatigue, and weight loss, which tend to develop slowly, over several months. The average rate of survival for someone with this disease is between three and five years. The term ILD is ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Lentivirus
''Lentivirus'' is a genus of retroviruses that cause chronic and deadly diseases characterized by long incubation periods, in humans and other mammalian species. The genus includes the human immunodeficiency virus (HIV), which causes AIDS. Lentiviruses are distributed worldwide, and are known to be hosted in apes, cows, goats, horses, cats, and sheep as well as several other mammals. Lentiviruses can integrate a significant amount of viral complementary DNA into the DNA of the host cell and can efficiently infect nondividing cells, so they are one of the most efficient methods of gene delivery. They can become endogenous, integrating their genome into the host germline genome, so that the virus is henceforth inherited by the host's descendants. Classification Five serogroups of lentiviruses are recognized, reflecting the vertebrate hosts with which they are associated (primates, sheep and goats, horses, domestic cats, and cattle). The primate lentiviruses are distinguished ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
University Of Iceland
The University of Iceland ( is, Háskóli Íslands ) is a public research university in Reykjavík, Iceland and the country's oldest and largest institution of higher education. Founded in 1911, it has grown steadily from a small civil servants' school to a modern comprehensive university, providing instruction for about 14,000 students in twenty-five faculties. Teaching and research is conducted in social sciences, humanities, law, medicine, natural sciences, engineering and teacher education. It has a campus concentrated around ''Suðurgata'' street in central Reykjavík, with additional facilities located in nearby areas as well as in the countryside. History The University of Iceland was founded by the Alþingi on 17 June 1911, uniting three former post-secondary institutions: ''Prestaskólinn'', ''Læknaskólinn'' and ''Lagaskólinn'', which taught theology, medicine and law, respectively. The university originally had only faculties for these three fields, in addition to a fa ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Slow Viruses
In everyday use and in kinematics, the speed (commonly referred to as ''v'') of an object is the magnitude of the change of its position over time or the magnitude of the change of its position per unit of time; it is thus a scalar quantity. The average speed of an object in an interval of time is the distance travelled by the object divided by the duration of the interval; the instantaneous speed is the limit of the average speed as the duration of the time interval approaches zero. Speed is not the same as velocity. Speed has the dimensions of distance divided by time. The SI unit of speed is the metre per second (m/s), but the most common unit of speed in everyday usage is the kilometre per hour (km/h) or, in the US and the UK, miles per hour (mph). For air and marine travel, the knot is commonly used. The fastest possible speed at which energy or information can travel, according to special relativity, is the speed of light in a vacuum ''c'' = metres per second (app ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Epidemiology
Epidemiology is the study and analysis of the distribution (who, when, and where), patterns and determinants of health and disease conditions in a defined population. It is a cornerstone of public health, and shapes policy decisions and evidence-based practice by identifying risk factors for disease and targets for preventive healthcare. Epidemiologists help with study design, collection, and statistical analysis of data, amend interpretation and dissemination of results (including peer review and occasional systematic review). Epidemiology has helped develop methodology used in clinical research, public health studies, and, to a lesser extent, basic research in the biological sciences. Major areas of epidemiological study include disease causation, transmission, outbreak investigation, disease surveillance, environmental epidemiology, forensic epidemiology, occupational epidemiology, screening, biomonitoring, and comparisons of treatment effects such as in clinical trials. ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
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