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Biocompatibles
Biocompatibles International plc is a medical technology company in the field of drug-device combination products. It was acquired by BTG plc in 2010, which was, in turn, acquired by Boston Scientific in 2019. Approved oncology products are supplied and marketed from facilities in Farnham, Surrey, UK and Oxford, Connecticut. Products include drug-eluting bead products that are used in more than 35 countries for the treatment of primary liver cancer (HCC), liver metastases from colorectal cancer and other cancers. The company supplies and markets brachytherapy products (radiation-delivering seeds) that are used to treat prostate cancer. Its UK research and development facilities are engaged in licensing and in new product development based on the company's core drug delivery technologies in the treatment of cancers. Its Cellmed unit in Alzenau, Germany, is developing a drug-eluting bead product for the treatment of stroke based on proprietary stem cell technology. Cellmed is ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Boston Scientific
Boston Scientific Corporation ("BSC"), incorporated in Delaware, is a biomedical/biotechnology engineering firm and multinational manufacturer of medical devices used in interventional medical specialties, including interventional radiology, interventional cardiology, peripheral interventions, neuromodulation, neurovascular intervention, electrophysiology, cardiac surgery, vascular surgery, endoscopy, oncology, urology and gynecology. Boston Scientific is widely known for the development of the Taxus Stent, a drug-eluting stent which is used to open clogged arteries. With the full acquisition of Cameron Health in June 2012, the company also became notable for offering a minimally invasive implantable cardioverter-defibrillator (ICD) which they call the EMBLEM subcutaneous implantable defibrillator (S-ICD). History Boston Scientific was formed years ago, on June 29, 1979, in Watertown, Massachusetts, as a holding company for the medical products company, Medi-Tech, Inc., an ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
BTG Plc
BTG Limited is an international specialist healthcare company that is developing and commercialising products targeting critical care, cancer and other disorders. The current name was adopted when the British Technology Group changed its name on 27 May 1998. BTG was a constituent of the FTSE 250 Index until it was acquired by Boston Scientific in August 2019. History In 1948, the National Research Development Corporation was formed with the purpose of commercialising innovations that arose from public funded research. This was complemented in November 1975 by the establishment of the National Enterprise Board to implement the then-Government's policy of moving public sector industry into commercial private enterprise. These two organisations were merged by the Government in 1981 to form a new, non-statutory body called the British Technology Group. It acted principally to license and commercialise the use of publicly funded developments. The Group was put onto a statutory footing ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Farnham
Farnham ( /ˈfɑːnəm/) is a market town and civil parish in Surrey, England, around southwest of London. It is in the Borough of Waverley, close to the county border with Hampshire. The town is on the north branch of the River Wey, a tributary of the Thames, and is at the western end of the North Downs. The civil parish, which includes the villages of Badshot Lea, Hale and Wrecclesham, covers and had a population of 39,488 in 2011. Among the prehistoric artefacts from the area is a woolly mammoth tusk, excavated in Badshot Lea at the start of the 21st century. The earliest evidence of human activity is from the Neolithic and, during the Roman period, tile making took place close to the town centre. The name "Farnham" is of Saxon origin and is generally agreed to mean "meadow where ferns grow". From at least 803, the settlement was under the control of the Bishops of Winchester and the castle was built as a residence for Bishop Henry de Blois in 1138. Henry VIII is thou ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Medtronic Inc
Medtronic plc is an American medical device company. The company's operational and executive headquarters are in Minneapolis, Minnesota, and its legal headquarters are in Ireland due to its acquisition of Irish-based Covidien in 2015. While it primarily operates in the United States, it operates in more than 150 countries and employs over 90,000 people. It develops and manufactures healthcare technologies and therapies. History Medtronic was founded in 1949 in Minneapolis by Earl Bakken and his brother-in-law, Palmer Hermundslie, as a medical equipment repair shop. Bakken invented several medical technology devices that continue to be used around the world today. Through his repair business, Bakken came to know C. Walton Lillehei, a doctor of heart surgery at the University of Minnesota Medical School. The deficiencies of the artificial pacemakers of the day were made painfully obvious following a power outage over Halloween in 1957, which affected large sections of Minnesota ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
London Stock Exchange
London Stock Exchange (LSE) is a stock exchange in the City of London, England, United Kingdom. , the total market value of all companies trading on LSE was £3.9 trillion. Its current premises are situated in Paternoster Square close to St Paul's Cathedral in the City of London. Since 2007, it has been part of the London Stock Exchange Group (LSEG, that it also lists ()). The LSE was the most-valued stock exchange in Europe from 2003 when records began till Autumn 2022, when the Paris exchange was briefly larger, until the LSE retook its position as Europe’s largest stock exchange 10 days later. History Coffee House The Royal Exchange had been founded by English financier Thomas Gresham and Sir Richard Clough on the model of the Antwerp Bourse. It was opened by Elizabeth I of England in 1571. During the 17th century, stockbrokers were not allowed in the Royal Exchange due to their rude manners. They had to operate from other establishments in the vicinity, notably Jona ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Microspheres
Microparticles are particles between 0.1 and 100 μm in size. Commercially available microparticles are available in a wide variety of materials, including ceramics, glass, polymers, and metals. Microparticles encountered in daily life include pollen, sand, dust, flour, and powdered sugar. Microparticles have a much larger surface-to-volume ratio than at the macroscale, and thus their behavior can be quite different. For example, metal microparticles can be explosive in air. Microspheres are spherical microparticles, and are used where consistent and predictable particle surface area is important. In biological systems, a microparticle is synonymous with a microvesicle, a type of extracellular vesicle (EV). Alternative definitions for size Mathematical: as the term "micro" refers to 10^, the range for micro would then be 10^ to 10^, or roughly 31.6 nm to 31.6 micrometers. However, general acceptance considers particles smaller than 100 nm nanoparticles. Rounding ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Embolic
An embolism is the lodging of an embolus, a blockage-causing piece of material, inside a blood vessel. The embolus may be a blood clot (thrombus), a fat globule (fat embolism), a bubble of air or other gas (gas embolism), amniotic fluid (amniotic fluid embolism), or foreign material. An embolism can cause partial or total blockage of blood flow in the affected vessel. Such a blockage (vascular occlusion) may affect a part of the body distant from the origin of the embolus. An embolism in which the embolus is a piece of thrombus is called a thromboembolism. An embolism is usually a pathological event, caused by illness or injury. Sometimes it is created intentionally for a therapeutic reason, such as to stop bleeding or to kill a cancerous tumor by stopping its blood supply. Such therapy is called embolization. Classification There are different types of embolism, some of which are listed below. Embolism can be classified based on where it enters the circulation, either in art ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Vascular Malformation
A vascular malformation is a blood vessel or lymph vessel abnormality. Vascular malformations are one of the classifications of vascular anomalies, the other grouping is vascular tumors. They may cause aesthetic problems as they have a growth cycle, and can continue to grow throughout life. Vascular malformations of the brain (VMBs) include those involving capillaries, and those involving the veins and arteries. Capillary malformations in the brain are known as cerebral cavernous malformations or ''capillary cavernous malformations'' (CCMs). Those involving the mix of vessels are known as cerebral arteriovenous malformations (AVMs or cAVMs). The arteriovenous type is the most common in the brain. Types A simple division of the vascular malformations is made into ''low-flow'' and ''high-flow'' types. Low-flow malformations involve a single type of blood or lymph vessel, and are known as ''simple vascular malformations''; high-flow malformations involve an artery. There are also ma ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Tumours
A neoplasm () is a type of abnormal and excessive growth of tissue. The process that occurs to form or produce a neoplasm is called neoplasia. The growth of a neoplasm is uncoordinated with that of the normal surrounding tissue, and persists in growing abnormally, even if the original trigger is removed. This abnormal growth usually forms a mass, when it may be called a tumor. ICD-10 classifies neoplasms into four main groups: benign neoplasms, in situ neoplasms, malignant neoplasms, and neoplasms of uncertain or unknown behavior. Malignant neoplasms are also simply known as cancers and are the focus of oncology. Prior to the abnormal growth of tissue, as neoplasia, cells often undergo an abnormal pattern of growth, such as metaplasia or dysplasia. However, metaplasia or dysplasia does not always progress to neoplasia and can occur in other conditions as well. The word is from Ancient Greek 'new' and 'formation, creation'. Types A neoplasm can be benign, potentially ma ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Embolisation
Embolization refers to the passage and lodging of an embolus within the bloodstream. It may be of natural origin (pathological), in which sense it is also called embolism, for example a pulmonary embolism; or it may be artificially induced (therapeutic), as a hemostatic treatment for bleeding or as a treatment for some types of cancer by deliberately blocking blood vessels to starve the tumor cells. In the cancer management application, the embolus, besides blocking the blood supply to the tumor, also often includes an ingredient to attack the tumor chemically or with irradiation. When it bears a chemotherapy drug, the process is called chemoembolization. Transcatheter arterial chemoembolization (TACE) is the usual form. When the embolus bears a radiopharmaceutical for unsealed source radiotherapy, the process is called radioembolization or selective internal radiation therapy (SIRT). Uses Embolization involves the selective occlusion of blood vessels by purposely introducin ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Cell Membrane
The cell membrane (also known as the plasma membrane (PM) or cytoplasmic membrane, and historically referred to as the plasmalemma) is a biological membrane that separates and protects the interior of all cells from the outside environment (the extracellular space). The cell membrane consists of a lipid bilayer, made up of two layers of phospholipids with cholesterols (a lipid component) interspersed between them, maintaining appropriate membrane fluidity at various temperatures. The membrane also contains membrane proteins, including integral proteins that span the membrane and serve as membrane transporters, and peripheral proteins that loosely attach to the outer (peripheral) side of the cell membrane, acting as enzymes to facilitate interaction with the cell's environment. Glycolipids embedded in the outer lipid layer serve a similar purpose. The cell membrane controls the movement of substances in and out of cells and organelles, being selectively permeable to ions a ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Phosphoryl-choline
:''Phosphorylcholine refers to the functional group derived from phosphocholine. Also not to be confused with phosphatidylcholine.'' Phosphorylcholine (abbreviated ChoP) is the hydrophilic polar head group of some phospholipids, which is composed of a negatively charged phosphate bonded to a small, positively charged choline group. Phosphorylcholine is part of the platelet-activating factor; the phospholipid phosphatidylcholine and sphingomyelin, the only phospholipid of the membrane that is not built with a glycerol backbone. Treatment of cell membranes, like those of RBCs, by certain enzymes, like some phospholipase A2 renders the phosphorylcholine moiety exposed to the external aqueous phase, and thus accessible for recognition by the immune system. Antibodies against phosphorylcholine are naturally occurring autoantibodies that are created by CD5+/ B-1 B cells and are referred to as non-pathogenic autoantibodies. Thrombus-resistant stents In interventional cardiology, ph ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
