Bert Achong
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Bert Achong
Bert Geoffrey Achong (6 December 1928 – 28 November 1996) was a Trinidadian-born pathologist known for co-discovering the Epstein–Barr virus through use of electron microscopy. Career Achong was born in Trinidad and Tobago and was of Chinese descent. After excelling in school in Trinidad and Tobago, he was awarded the Jerningham Gold Medal and the Colonial Scholarship to study in Europe. He moved to Europe at 18 and enrolled at University College Dublin, where he received his medical degree in 1953. In 1955 he moved to London, and worked at Lambeth Hospital in London in Clinical Pathology. In 1963, he joined Michael Anthony Epstein's research group at Middlesex Hospital. He moved with Epstein to the Department of Pathology at University of Bristol in 1968, where he was a popular lecturer on cellular pathology until his retirement in 1985. He died of a brain tumour in 1996. Epstein–Barr virus Achong, Anthony Epstein and Yvonne Barr discovered the first example of ...
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Port Of Spain
Port of Spain (Spanish: ''Puerto España''), officially the City of Port of Spain (also stylized Port-of-Spain), is the capital of Trinidad and Tobago and the third largest municipality, after Chaguanas and San Fernando. The city has a municipal population of 37,074 (2011 census), an urban population of 81,142 (2011 estimate) and a transient daily population of 250,000. It is located on the Gulf of Paria, on the northwest coast of the island of Trinidad and is part of a larger conurbation stretching from Chaguaramas in the west to Arima in the east with an estimated population of 600,000. The city serves primarily as a retail and administrative centre and it has been the capital of the island since 1757. It is also an important financial services centre for the CaribbeanCIA World Factbook Trinidad an ...
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Anthony Epstein
Sir Michael Anthony Epstein (born 18 May 1921) is a British pathologist and academic. He is one of the discoverers of the Epstein–Barr virus, along with Yvonne Barr and Bert Achong. Personal life Epstein was born on 18 May 1921, and educated at St Paul's School in London, Trinity College, Cambridge, and Middlesex Hospital Medical School. In 2006, Epstein was awarded a D.Sc. from Bristol. Epstein turned 100 in May 2021. He is a Patron of Humanists UK. Career Epstein was Professor of Pathology, 1968–1985 (now professor emeritus), head of department, 1968–1982 at the University of Bristol. In 1979 he was elected a Fellow of the Royal Society of London and was its vice-president from 1986 to 1991. He was awarded its Royal Medal in 1992. Epstein was awarded the CBE in 1985, and knighted in 1991. He was a fellow of Wolfson College, Oxford, from 1986 until 2001, and has been an honorary fellow since 2001. Epstein was also a founding Fellow of the Academy of Medical Scie ...
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Trinidad And Tobago People Of Chinese Descent
Trinidad is the larger and more populous of the two major islands of Trinidad and Tobago. The island lies off the northeastern coast of Venezuela and sits on the continental shelf of South America. It is often referred to as the southernmost island in the West Indies. With an area of , it is also the fifth largest in the West Indies. Name The original name for the island in the Arawaks' language was which meant "Land of the Hummingbird". Christopher Columbus renamed it ('The Island of the Trinity'), fulfilling a vow he had made before setting out on his third voyage. This has since been shortened to ''Trinidad''. History Caribs and Arawaks lived in Trinidad long before Christopher Columbus encountered the islands on his third voyage on 31 July 1498. The island remained Spanish until 1797, but it was largely settled by French colonists from the French Caribbean, especially Martinique.Besson, Gerard (2000-08-27). "Land of Beginnings – A historical digest", ''Newsday N ...
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Trinidad And Tobago Pathologists
Trinidad is the larger and more populous of the two major islands of Trinidad and Tobago. The island lies off the northeastern coast of Venezuela and sits on the continental shelf of South America. It is often referred to as the southernmost island in the West Indies. With an area of , it is also the fifth largest in the West Indies. Name The original name for the island in the Arawaks' language was which meant "Land of the Hummingbird". Christopher Columbus renamed it ('The Island of the Trinity'), fulfilling a vow he had made before setting out on his third voyage. This has since been shortened to ''Trinidad''. History Caribs and Arawaks lived in Trinidad long before Christopher Columbus encountered the islands on his third voyage on 31 July 1498. The island remained Spanish until 1797, but it was largely settled by French colonists from the French Caribbean, especially Martinique.Besson, Gerard (2000-08-27). "Land of Beginnings – A historical digest", ''Newsday N ...
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1996 Deaths
File:1996 Events Collage.png, From left, clockwise: A bomb explodes at Centennial Olympic Park in Atlanta, set off by a radical anti-abortionist; The center fuel tank explodes on TWA Flight 800, causing the plane to crash and killing everyone on board; Eight people die in a blizzard on Mount Everest; Dolly the Sheep becomes the first mammal to have been cloned from an adult somatic cell; The Port Arthur Massacre occurs on Tasmania, and leads to major changes in Australia's gun laws; Macarena, sung by Los del Río and remixed by The Bayside Boys, becomes a major dance craze and cultural phenomenon; Ethiopian Airlines Flight 961 crash-ditches off of the Comoros Islands after the plane was hijacked; the 1996 Summer Olympics are held in Atlanta, marking the Centennial (100th Anniversary) of the modern Olympic Games., 300x300px, thumb rect 0 0 200 200 Centennial Olympic Park bombing rect 200 0 400 200 TWA FLight 800 rect 400 0 600 200 1996 Mount Everest disaster rect 0 200 30 ...
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1928 Births
Nineteen or 19 may refer to: * 19 (number), the natural number following 18 and preceding 20 * one of the years 19 BC, AD 19, 1919, 2019 Films * ''19'' (film), a 2001 Japanese film * ''Nineteen'' (film), a 1987 science fiction film Music * 19 (band), a Japanese pop music duo Albums * ''19'' (Adele album), 2008 * ''19'', a 2003 album by Alsou * ''19'', a 2006 album by Evan Yo * ''19'', a 2018 album by MHD * ''19'', one half of the double album ''63/19'' by Kool A.D. * ''Number Nineteen'', a 1971 album by American jazz pianist Mal Waldron * ''XIX'' (EP), a 2019 EP by 1the9 Songs * "19" (song), a 1985 song by British musician Paul Hardcastle. * "Nineteen", a song by Bad4Good from the 1992 album '' Refugee'' * "Nineteen", a song by Karma to Burn from the 2001 album ''Almost Heathen''. * "Nineteen" (song), a 2007 song by American singer Billy Ray Cyrus. * "Nineteen", a song by Tegan and Sara from the 2007 album '' The Con''. * "XIX" (song), a 2014 song by Slipk ...
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Retrovirus
A retrovirus is a type of virus that inserts a DNA copy of its RNA genome into the DNA of a host cell that it invades, thus changing the genome of that cell. Once inside the host cell's cytoplasm, the virus uses its own reverse transcriptase enzyme to produce DNA from its RNA genome, the reverse of the usual pattern, thus ''retro'' (backwards). The new DNA is then incorporated into the host cell genome by an integrase enzyme, at which point the retroviral DNA is referred to as a provirus. The host cell then treats the viral DNA as part of its own genome, transcribing and translating the viral genes along with the cell's own genes, producing the proteins required to assemble new copies of the virus. Although retroviruses have different subfamilies, they have three basic groups: the oncoretroviruses (oncogenic retroviruses), the lentiviruses (slow retroviruses) and the spumaviruses (foamy viruses). The oncoretroviruses are able to cause cancer in some species, the lentiviru ...
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Human Foamy Virus
Human foamy virus (HFV) is a retrovirus and specifically belongs to the genus ''Spumavirus''. The spumaviruses are complex and significantly different from the other six genera of retroviruses in several ways. The foamy viruses derive their name from the characteristic ‘foamy’ appearance of the cytopathic effect (CPE) induced in the cells. Foamy virus in humans occurs only as a result of zoonotic infection. Discovery The first description of foamy virus (FV) was in 1954. It was found as a contaminant in primary monkey kidney cultures. The first isolate of the “foamy viral agent” was in 1955. Not too long after this, it was isolated from a wide variety of New and Old World monkeys, cats, and cows. It was not until several years later that humans entered the scene. In 1971, a viral agent with FV-like characteristics was isolated from lymphoblastoid cells released from a human nasopharyngeal carcinoma (NPC) from a Kenyan patient. The agent was termed a human FV bec ...
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Burkitt Lymphoma
Burkitt lymphoma is a cancer of the lymphatic system, particularly B lymphocytes found in the germinal center. It is named after Denis Parsons Burkitt, the Irish surgeon who first described the disease in 1958 while working in equatorial Africa. The overall cure rate for Burkitt lymphoma in developed countries is about 90%, and it is worse in low-income countries. Burkitt lymphoma is uncommon in adults, in whom it has a worse prognosis. Classification Burkitt lymphoma can be divided into three main clinical variants: the endemic, the sporadic, and the immunodeficiency-associated variants. By morphology (i.e., microscopic appearance), immunophenotype, and genetics, the variants of Burkitt lymphoma are alike. * The endemic variant (also called "African variant") most commonly occurs in children living in malaria-endemic regions of the world (e.g., equatorial Africa, Brazil, and Papua New Guinea). Epstein–Barr virus (EBV) infection is found in nearly all patients. Chronic mala ...
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Cell Culture
Cell culture or tissue culture is the process by which cells are grown under controlled conditions, generally outside of their natural environment. The term "tissue culture" was coined by American pathologist Montrose Thomas Burrows. This technique is also called micropropagation. After the cells of interest have been isolated from living tissue, they can subsequently be maintained under carefully controlled conditions the need to be kept at body temperature (37 °C) in an incubator. These conditions vary for each cell type, but generally consist of a suitable vessel with a substrate or rich medium that supplies the essential nutrients (amino acids, carbohydrates, vitamins, minerals), growth factors, hormones, and gases ( CO2, O2), and regulates the physio-chemical environment (pH buffer, osmotic pressure, temperature). Most cells require a surface or an artificial substrate to form an adherent culture as a monolayer (one single-cell thick), whereas others can be grown ...
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The Lancet
''The Lancet'' is a weekly peer-reviewed general medical journal and one of the oldest of its kind. It is also the world's highest-impact academic journal. It was founded in England in 1823. The journal publishes original research articles, review articles ("seminars" and "reviews"), editorials, book reviews, correspondence, as well as news features and case reports. ''The Lancet'' has been owned by Elsevier since 1991, and its editor-in-chief since 1995 has been Richard Horton. The journal has editorial offices in London, New York City, and Beijing. History ''The Lancet'' was founded in 1823 by Thomas Wakley, an English surgeon who named it after the surgical instrument called a lancet (scalpel). Members of the Wakley family retained editorship of the journal until 1908. In 1921, ''The Lancet'' was acquired by Hodder & Stoughton. Elsevier acquired ''The Lancet'' from Hodder & Stoughton in 1991. Impact According to the ''Journal Citation Reports'', the journal has a 202 ...
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Virus
A virus is a submicroscopic infectious agent that replicates only inside the living cells of an organism. Viruses infect all life forms, from animals and plants to microorganisms, including bacteria and archaea. Since Dmitri Ivanovsky's 1892 article describing a non-bacterial pathogen infecting tobacco plants and the discovery of the tobacco mosaic virus by Martinus Beijerinck in 1898,Dimmock p. 4 more than 9,000 virus species have been described in detail of the millions of types of viruses in the environment. Viruses are found in almost every ecosystem on Earth and are the most numerous type of biological entity. The study of viruses is known as virology, a subspeciality of microbiology. When infected, a host cell is often forced to rapidly produce thousands of copies of the original virus. When not inside an infected cell or in the process of infecting a cell, viruses exist in the form of independent particles, or ''virions'', consisting of (i) the genetic material, i. ...
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