Bas-Congo Tibrovirus
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Bas-Congo Tibrovirus
''Bas-Congo tibrovirus'' (BASV) is a poorly characterized rhabdovirus discovered in the blood of a patient who survived a severe illness resembling hemorrhagic fever.Grard G, Fair JN, Lee D, et al. A novel rhabdovirus associated with acute hemorrhagic fever in central Africa ublished correction appears in PLoS Pathog. 2016 Mar;12(3):e1005503 ublished correction appears in PLoS Pathog. 2017 Sep 7;13(9):e1006583 PLoS Pathog. 2012;8(9):e1002924. doi:10.1371/journal.ppat.1002924 The virus was named after the former Democratic Republic of Congo province of Bas-Congo (now Kongo Central). BASV was discovered using next-generation sequencing and attempts to isolate the virus were not successful. BASV RNA has only been detected in one individual and its role as a human pathogen has not been established. Discovery In the spring of 2009, two teenagers living in Mangala, a small village located in the westernmost province of the Democratic Republic of Congo, developed a severe illness ...
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Kongo Central
Kongo Central ( kg, Kongo dia Kati ), formerly Bas-Congo is one of the 26 provinces of the Democratic Republic of the Congo. Its capital is Matadi. History At the time of independence, the area now encompassing Kongo Central was part of the greater province of Kinshasa, Léopoldville, along with the capital city of Kinshasa and the districts of Kwango District, Kwango, Kwilu District, Kwilu and Mai-Ndombe District, Mai-Ndombe. Under Belgian colonial rule, the province was known as Bas-Congo District, Bas-Congo (as in "Lower Congo River") and was renamed Kongo Central after independence. (Article 1) Under the regime of Mobutu Sese Seko from 1965 to 1997, the Congo river was renamed as ''Zaire''. The province was named as Bas-Zaïre. The name was later reverted to Bas-Congo. It was subsequently renamed as Kongo Central in 2015. Geography Kongo Central is the only province in the country with an ocean coastline; it has narrow frontage on the Atlantic Ocean. It borders the prov ...
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Tibrovirus
''Tibrovirus'' is a poorly characterized genus of viruses in the family ''Rhabdoviridae'', order ''Mononegavirales''. There are 8 members of the genus. Tibroviruses have been isolated from biting midges, cattle, and humans. None of the tibroviruses, except for Bas-Congo virus, have been associated with any diseases. Genus members * ''Bas-Congo virus ''Bas-Congo tibrovirus'' (BASV) is a poorly characterized rhabdovirus discovered in the blood of a patient who survived a severe illness resembling hemorrhagic fever.Grard G, Fair JN, Lee D, et al. A novel rhabdovirus associated with acute hemorrh ...'' (BASV) was discovered in 2009 in the Democratic Republic of Congo in a blood sample collected from a 32-year-old male who survived a severe illness resembling hemorrhagic fever.  BASV could not be isolated from the patient’s sample has not been established as a human pathogen. * '' Beatrice Hill virus'' (BHV) was isolated from a pool of biting midges (Culicoides peregrinus) in 198 ...
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Culicoides
''Culicoides'' is a genus of biting midges in the family Ceratopogonidae. There are over 1000 species in the genus,Connelly, C. RBiting midges: ''Culicoides'' spp.Featured Creatures, Entomology and Nematology Department, University of Florida IFAS. August 2013 Edition. which is divided into many subgenera. Several species are known to be vectors of various diseases and parasites which can affect animals. Like ''Leptoconops'', the genus has a long fossil record, with earliest known fossils being from Burmese amber, around 99 million years old. Notable taxa The systematics and taxonomy of this genus are confused. A large number of species are of unknown relations to those that have been assigned to subgenera already. Furthermore, many subgenera are sometimes elevated to full genus status, or additional genera (such as '' Paradasyhelea'') are included as subgenera herein. A widely cited, periodically updated, subgeneric classification of species of ''Culicoides'' begins with the w ...
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Viral Diseases
Viral means "relating to viruses" (small infectious agents). Viral may also refer to: Viral behavior, or virality Memetic behavior likened that of a virus, for example: * Viral marketing, the use of existing social networks to spread a marketing message * Viral phenomenon, relating to contagion theory or the "virality" of network culture, such as a meme * Viral video, a video that quickly attains a high popularity Titled works * ''Viral'' (2016 American film), a 2016 American science fiction horror drama * ''Viral'' (2016 Hindi film), an Indian Bollywood film based on social media * ''Viral'' (web series), a 2014 Brazilian comedy web series * '' V/H/S: Viral'', an American anthology horror film * '' Viral: The Search for the Origin of COVID-19'', a book by Alina Chand and Matt Ridley See also * ''Virals'', a novel series by Kathy Reichs * Virulence Virulence is a pathogen's or microorganism's ability to cause damage to a host. In most, especially in animal system ...
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Rhabdoviridae
''Rhabdoviridae'' is a family of negative-strand RNA viruses in the order ''Mononegavirales''. Vertebrates (including mammals and humans), invertebrates, plants, fungi and protozoans serve as natural hosts. Diseases associated with member viruses include rabies encephalitis caused by the rabies virus, and flu-like symptoms in humans caused by vesiculoviruses. The name is derived from Ancient Greek , meaning rod, referring to the shape of the viral particles. The family has 40 genera, most assigned to three subfamilies. Structure The individual virus particles (virions) of rhabdoviruses are composed of RNA, protein, carbohydrate and lipid. They have complex bacilliform or bullet-like shapes. All these viruses have structural similarities and have been classified as a single family. The virions are about 75 nm wide and 180 nm long. Rhabdoviruses are enveloped and have helical nucleocapsids and their genomes are linear, around 11–15 kb in length. Rhabdoviruses c ...
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Zoonoses
A zoonosis (; plural zoonoses) or zoonotic disease is an infectious disease of humans caused by a pathogen (an infectious agent, such as a bacterium, virus, parasite or prion) that has jumped from a non-human (usually a vertebrate) to a human. Typically, the first infected human transmits the infectious agent to at least one other human, who, in turn, infects others. Major modern diseases such as Ebola virus disease and salmonellosis are zoonoses. HIV was a zoonotic disease transmitted to humans in the early part of the 20th century, though it has now evolved into a separate human-only disease. Most strains of influenza that infect humans are human diseases, although many strains of bird flu and swine flu are zoonoses; these viruses occasionally recombine with human strains of the flu and can cause pandemics such as the 1918 Spanish flu or the 2009 swine flu. ''Taenia solium'' infection is one of the neglected tropical diseases with public health and veterinary concern in ende ...
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Hemorrhagic Fevers
Bleeding, hemorrhage, haemorrhage or blood loss, is blood escaping from the circulatory system from damaged blood vessels. Bleeding can occur internally, or externally either through a natural opening such as the mouth, nose, ear, urethra, vagina or anus, or through a puncture in the skin. Hypovolemia is a massive decrease in blood volume, and death by excessive loss of blood is referred to as exsanguination. Typically, a healthy person can endure a loss of 10–15% of the total blood volume without serious medical difficulties (by comparison, blood donation typically takes 8–10% of the donor's blood volume). The stopping or controlling of bleeding is called hemostasis and is an important part of both first aid and surgery. Types * Upper head ** Intracranial hemorrhage – bleeding in the skull. ** Cerebral hemorrhage – a type of intracranial hemorrhage, bleeding within the brain tissue itself. ** Intracerebral hemorrhage – bleeding in the brain caused by the ruptu ...
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