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Bartolomeo Gosio
Bartolomeo Gosio (17 March 1863 – 13 April 1944) was an Italian medical scientist. He discovered a toxic fume, eponymously named "Gosio gas", which is produced by microorganisms, that killed many people. He identified the chemical nature of the gas as an arsenic compound (arsine), but incorrectly named it as diethylarsine. He also discovered an antibacterial compound called mycophenolic acid from the mould '' Penicillium brevicompactum''. He demonstrated that the novel compound was effective against the deadly anthrax bacterium, ''Bacillus anthracis''. This was the first antibiotic compound isolated in pure and crystallised form. Though the original compound was abandoned in clinical practice due to its adverse effects, its chemical derivative mycophenolate mofetil became the drug of choice as an immunosuppressant in kidney, heart, and liver transplantations. Biography Gosio was born in Magliano Alfieri, Piedmont, Italy. His father Giacomo Gosio, a veterinarian, died just when ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Magliano Alfieri
Magliano Alfieri is a ''comune'' (municipality) in the Province of Cuneo in the Italian region Piedmont, located about southeast of Turin and about northeast of Cuneo. As of 31 December 2004, it had a population of 1,726 and an area of .All demographics and other statistics: Italian statistical institute Istat. Magliano Alfieri borders the following municipalities: Castagnito, Castagnole delle Lanze, Castellinaldo, Govone, Neive Neive is a ''comune'' (municipality) in the Province of Cuneo in the Italian region Piedmont, located about southeast of Turin and about northeast of Cuneo. Neive borders the following municipalities: Barbaresco, Castagnito, Castagnole delle La ..., and Priocca. Demographic evolution Colors= id:lightgrey value:gray(0.9) id:darkgrey value:gray(0.8) id:sfondo value:rgb(1,1,1) id:barra value:rgb(0.6,0.7,0.8) ImageSize = width:455 height:303 PlotArea = left:50 bottom:50 top:30 right:30 DateFormat = x.y Period = from:0 till:3000 Tim ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Max Rubner
Max Rubner (2 June 1854, Munich27 April 1932, Berlin) was a German physiologist and hygienist. Academic career He studied at the University of Munich and worked as an assistant under Adolf von Baeyer and Carl von Voit (doctorate 1878). Later on, he taught as a professor at the University of Marburg (1885–1891), and in 1891 succeeded Robert Koch as a professor of hygiene at the University of Berlin. In 1909 he succeeded Theodor Wilhelm Engelmann as chair of physiology at Berlin. Rubner was co-founder of the '' Kaiser-Wilhelm Institut für Arbeitsphysiologie'', and became its director in 1913. With his assistant Gerhard Albrecht, Rubner set out to study labour not just as the expenditure of energy, but also the use of intellect. They rejected taylorism as being over concerned with economic outputs, but rather advocated an approach which was more concerned with a biophysical approach to the elimination of fatigue. Contributions Rubner is remembered for his research in metabol ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Sapienza University Of Rome Alumni
The Sapienza University of Rome ( it, Sapienza – Università di Roma), also called simply Sapienza or the University of Rome, and formally the Università degli Studi di Roma "La Sapienza", is a public research university located in Rome, Italy. It is one of the largest European universities by enrollments and one of the oldest in history, founded in 1303. The university is one of the most prestigious Italian universities in the world, commonly ranking first in national rankings and in Southern Europe. In 2018, 2019, 2021 and 2022 it ranked first in the world for classics and ancient history. Most of the Italian ruling class studied at the Sapienza. The Sapienza has educated numerous notable alumni, including many Nobel laureates, Presidents of the European Parliament and European Commissioners, heads of several nations, notable religious figures, scientists and astronauts. In September 2018, it was included in the top 100 of the QS World University Rankings Graduate Emplo ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
University Of Turin Alumni
A university () is an institution of higher (or tertiary) education and research which awards academic degrees in several academic disciplines. Universities typically offer both undergraduate and postgraduate programs. In the United States, the designation is reserved for colleges that have a graduate school. The word ''university'' is derived from the Latin ''universitas magistrorum et scholarium'', which roughly means "community of teachers and scholars". The first universities were created in Europe by Catholic Church monks. The University of Bologna (''Università di Bologna''), founded in 1088, is the first university in the sense of: *Being a high degree-awarding institute. *Having independence from the ecclesiastic schools, although conducted by both clergy and non-clergy. *Using the word ''universitas'' (which was coined at its foundation). *Issuing secular and non-secular degrees: grammar, rhetoric, logic, theology, canon law, notarial law.Hunt Janin: "The university i ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Italian Public Health Doctors
Italian(s) may refer to: * Anything of, from, or related to the people of Italy over the centuries ** Italians, an ethnic group or simply a citizen of the Italian Republic or Italian Kingdom ** Italian language, a Romance language *** Regional Italian, regional variants of the Italian language ** Languages of Italy, languages and dialects spoken in Italy ** Italian culture, cultural features of Italy ** Italian cuisine, traditional foods ** Folklore of Italy, the folklore and urban legends of Italy ** Mythology of Italy, traditional religion and beliefs Other uses * Italian dressing, a vinaigrette-type salad dressing or marinade * Italian or Italian-A, alternative names for the Ping-Pong virus, an extinct computer virus See also * * * Italia (other) * Italic (other) * Italo (other) * The Italian (other) * Italian people (other) Italian people may refer to: * in terms of ethnicity: all ethnic Italians, in and outside of Italy * in ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
1944 Deaths
Events Below, the events of World War II have the "WWII" prefix. January * January 2 – WWII: ** Free France, Free French General Jean de Lattre de Tassigny is appointed to command First Army (France), French Army B, part of the Sixth United States Army Group in North Africa. ** Landing at Saidor: 13,000 US and Australian troops land on Papua New Guinea, in an attempt to cut off a Japanese retreat. * January 8 – WWII: Philippine Commonwealth troops enter the province of Ilocos Sur in northern Luzon and attack Japanese forces. * January 11 ** President of the United States Franklin D. Roosevelt proposes a Second Bill of Rights for social and economic security, in his State of the Union address. ** The Nazi German administration expands Kraków-Płaszów concentration camp into the larger standalone ''Konzentrationslager Plaszow bei Krakau'' in occupied Poland. * January 12 – WWII: Winston Churchill and Charles de Gaulle begin a 2-day conference in Marrakech ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
1863 Births
Events January–March * January 1 – Abraham Lincoln signs the Emancipation Proclamation during the third year of the American Civil War, making the abolition of slavery in the Confederate states an official war goal. It proclaims the freedom of 3.1 million of the nation's four million slaves and immediately frees 50,000 of them, with the rest freed as Union armies advance. * January 2 – Lucius Tar Painting Master Company (''Teerfarbenfabrik Meirter Lucius''), predecessor of Hoechst, as a worldwide chemical manufacturing brand, founded in a suburb of Frankfurt am Main, Germany. * January 4 – The New Apostolic Church, a Christian and chiliastic church, is established in Hamburg, Germany. * January 7 – In the Swiss canton of Ticino, the village of Bedretto is partly destroyed and 29 killed, by an avalanche. * January 8 ** The Yorkshire County Cricket Club is founded at the Adelphi Hotel, in Sheffield, England. ** American Civil War – ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Novartis Foundation
The Novartis Foundation (formerly known as the Novartis Foundation for Sustainable Development) is a non-profit organization and part of the corporate responsibility portfolio of Novartis in Basel, Switzerland. The foundation conducts projects to improve health, mostly in sub-Saharan Africa and in south-east Asia. History The Novartis Foundation has been one of the leading organizations in the private sector for international development for the last 35 years. The humanitarian engagement of the Novartis Foundation goes back to the 1960s, when the Basel-based companies Novartis, Ciba, Geigy, Sandoz, Durand & Huguenin, Hoffmann-La Roche and Lonza Group, Lonza founded the Basel Foundation for Developing Countries. The Basel Foundation, for example, supported the field laboratory of the Swiss Tropical Institute (now known as the Ifakara Health Institute) located in Ifakara, which still works closely with the Novartis Foundation. Today, the Novartis Foundation focuses its work on th ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Hoffmann-La Roche
F. Hoffmann-La Roche AG, commonly known as Roche, is a Swiss multinational healthcare company that operates worldwide under two divisions: Pharmaceuticals and Diagnostics. Its holding company, Roche Holding AG, has shares listed on the SIX Swiss Exchange. The company headquarters are located in Basel. Roche is the fifth largest pharmaceutical company in the world by revenue, and the leading provider of cancer treatments globally. The company controls the American biotechnology company Genentech, which is a wholly owned affiliate, and the Japanese biotechnology company Chugai Pharmaceuticals, as well as the United States-based companies Ventana and Foundation Medicine. Roche's revenues during fiscal year 2020 were 58.32 billion Swiss francs. Descendants of the founding Hoffmann and Oeri families own slightly over half of the bearer shares with voting rights (a pool of family shareholders 45%, and Maja Oeri a further 5% apart), with Swiss pharma firm Novartis owning a furth ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Immunosuppressant Drug
Immunosuppressive drugs, also known as immunosuppressive agents, immunosuppressants and antirejection medications, are drugs that inhibit or prevent activity of the immune system. Classification Immunosuppressive drugs can be classified into five groups: * glucocorticoids * cytostatics * antibodies * drugs acting on immunophilins * other drugs Glucocorticoids In pharmacologic (supraphysiologic) doses, glucocorticoids, such as prednisone, dexamethasone, and hydrocortisone are used to suppress various allergic, inflammatory, and autoimmune disorders. They are also administered as posttransplantory immunosuppressants to prevent the acute transplant rejection and graft-versus-host disease. Nevertheless, they do not prevent an infection and also inhibit later reparative processes. Immunosuppressive mechanism Glucocorticoids suppress cell-mediated immunity. They act by inhibiting genes that code for the cytokines Interleukin 1 (IL-1), IL-2, IL-3, IL-4, IL-5, IL-6, IL ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Nervous System
In biology, the nervous system is the highly complex part of an animal that coordinates its actions and sensory information by transmitting signals to and from different parts of its body. The nervous system detects environmental changes that impact the body, then works in tandem with the endocrine system to respond to such events. Nervous tissue first arose in wormlike organisms about 550 to 600 million years ago. In vertebrates it consists of two main parts, the central nervous system (CNS) and the peripheral nervous system (PNS). The CNS consists of the brain and spinal cord. The PNS consists mainly of nerves, which are enclosed bundles of the long fibers or axons, that connect the CNS to every other part of the body. Nerves that transmit signals from the brain are called motor nerves or '' efferent'' nerves, while those nerves that transmit information from the body to the CNS are called sensory nerves or '' afferent''. Spinal nerves are mixed nerves that serve both fu ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Volatile Organic Compound
Volatile organic compounds (VOCs) are organic compounds that have a high vapour pressure at room temperature. High vapor pressure correlates with a low boiling point, which relates to the number of the sample's molecules in the surrounding air, a trait known as volatility. VOCs are responsible for the odor of scents and perfumes as well as pollutants. VOCs play an important role in communication between animals and plants, e.g. attractants for pollinators, protection from predation, and even inter-plant interactions. Some VOCs are dangerous to human health or cause harm to the environment. Anthropogenic VOCs are regulated by law, especially indoors, where concentrations are the highest. Most VOCs are not acutely toxic, but may have long-term chronic health effects. Definitions Diverse definitions of the term VOC are in use. Canada Health Canada classifies VOCs as organic compounds that have boiling points roughly in the range of . The emphasis is placed on commonly encountere ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
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