Barostat
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Barostat
A barostat is a device used to maintain constant pressure in a closed chamber. Its main principle is providing constant pressures in a balloon by means of a pneumatic pump. Barostats are frequently used in neurogastroenterology research, where they are used for measuring gut wall tension or sensory thresholds in the gut. A specially designed instrument is needed in neurogastroenterology research since the gut wall has an outstanding capacity to expand and contract spontaneously and by reflex. When this occurs, a balloon placed anywhere in the gut has to be inflated or deflated very rapidly in order to maintain a constant pressure in this balloon. Barostat-balloon systems have been used anywhere in the gut, including the esophagus The esophagus ( American English) or oesophagus (British English; both ), non-technically known also as the food pipe or gullet, is an organ in vertebrates through which food passes, aided by peristaltic contractions, from the pharynx t ...
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Barostat Balloon Rectal
A barostat is a device used to maintain constant pressure in a closed chamber. Its main principle is providing constant pressures in a balloon by means of a pneumatics, pneumatic pump. Barostats are frequently used in neurogastroenterology research, where they are used for measuring gastrointestinal tract, gut wall tension (mechanics), tension or sensory thresholds in the gut. A specially designed instrument is needed in neurogastroenterology research since the gut wall has an outstanding capacity to expand and Muscle contraction, contract spontaneously and by reflex. When this occurs, a balloon placed anywhere in the gut has to be inflated or deflated very rapidly in order to maintain a constant pressure in this balloon. Barostat-balloon systems have been used anywhere in the gut, including the esophagus, stomach, small bowel, colon (anatomy), colon, and the rectum, rectum ampulla. Computer-driven barostats have widely been used to assess sensation and pain thresholds in the ...
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Pneumatics
Pneumatics (from Greek ‘wind, breath’) is a branch of engineering that makes use of gas or pressurized air. Pneumatic systems used in industry are commonly powered by compressed air or compressed inert gases. A centrally located and electrically-powered compressor powers cylinders, air motors, pneumatic actuators, and other pneumatic devices. A pneumatic system controlled through manual or automatic solenoid valves is selected when it provides a lower cost, more flexible, or safer alternative to electric motors, and hydraulic actuators. Pneumatics also has applications in dentistry, construction, mining, and other areas. Gases used in pneumatic systems Pneumatic systems in fixed installations, such as factories, use compressed air because a sustainable supply can be made by compressing atmospheric air. The air usually has moisture removed, and a small quantity of oil is added at the compressor to prevent corrosion and lubricate mechanical components. Factory-plumb ...
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Psychophysics
Psychophysics quantitatively investigates the relationship between physical stimuli and the sensations and perceptions they produce. Psychophysics has been described as "the scientific study of the relation between stimulus and sensation" or, more completely, as "the analysis of perceptual processes by studying the effect on a subject's experience or behaviour of systematically varying the properties of a stimulus along one or more physical dimensions". ''Psychophysics'' also refers to a general class of methods that can be applied to study a perceptual system. Modern applications rely heavily on threshold measurement, ideal observer analysis, and signal detection theory. Psychophysics has widespread and important practical applications. For example, in the study of digital signal processing, psychophysics has informed the development of models and methods of lossy compression. These models explain why humans perceive very little loss of signal quality when audio and video sign ...
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Small Bowel
The small intestine or small bowel is an organ in the gastrointestinal tract where most of the absorption of nutrients from food takes place. It lies between the stomach and large intestine, and receives bile and pancreatic juice through the pancreatic duct to aid in digestion. The small intestine is about long and folds many times to fit in the abdomen. Although it is longer than the large intestine, it is called the small intestine because it is narrower in diameter. The small intestine has three distinct regions – the duodenum, jejunum, and ileum. The duodenum, the shortest, is where preparation for absorption through small finger-like protrusions called villi begins. The jejunum is specialized for the absorption through its lining by enterocytes: small nutrient particles which have been previously digested by enzymes in the duodenum. The main function of the ileum is to absorb vitamin B12, bile salts, and whatever products of digestion that were not absorbed by the jej ...
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Enteric Nervous System
The enteric nervous system (ENS) or intrinsic nervous system is one of the main divisions of the autonomic nervous system (ANS) and consists of a mesh-like system of neurons that governs the function of the gastrointestinal tract. It is capable of acting independently of the sympathetic and parasympathetic nervous systems, although it may be influenced by them. The ENS is nicknamed the "second brain". It is derived from neural crest cells. The enteric nervous system is capable of operating independently of the brain and spinal cord, but does rely on innervation from the vagus nerve and prevertebral ganglia in healthy subjects. However, studies have shown that the system is operable with a severed vagus nerve. The neurons of the enteric nervous system control the motor functions of the system, in addition to the secretion of gastrointestinal enzymes. These neurons communicate through many neurotransmitters similar to the CNS, including acetylcholine, dopamine, and serotonin. Th ...
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Random
In common usage, randomness is the apparent or actual lack of pattern or predictability in events. A random sequence of events, symbols or steps often has no :wikt:order, order and does not follow an intelligible pattern or combination. Individual random events are, by definition, unpredictable, but if the probability distribution is known, the frequency of different outcomes over repeated events (or "trials") is predictable.Strictly speaking, the frequency of an outcome will converge almost surely to a predictable value as the number of trials becomes arbitrarily large. Non-convergence or convergence to a different value is possible, but has probability zero. For example, when throwing two dice, the outcome of any particular roll is unpredictable, but a sum of 7 will tend to occur twice as often as 4. In this view, randomness is not haphazardness; it is a measure of uncertainty of an outcome. Randomness applies to concepts of chance, probability, and information entropy. T ...
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Paradigm (experimental)
In the behavioural sciences (e.g. psychology, biology, neurosciences), an experimental paradigm, is an experimental setup or way of conducting a certain type of experiment (a protocol) that is defined by certain fine-tuned standards, and often has a theoretical background. A paradigm in this technical sense, however, is not a way of thinking as it is in the epistemological meaning ( paradigm). The more paradigms which are attempted, and the more variables within a single paradigm are attempted, with the same results, the more sure one is of the results, that, "the effect is a true one and not merely a product of artifacts engendered by the use of a particular paradigm." The three core factors of paradigm design may be considered: "(a) ...the 'nuts and bolts' of the paradigm itself...; (b) ...implementation concerns...; and (c) resources available."Tully, Laura M. and Boudewyn, Megan A. (2018).Creating a Novel Experimental Paradigm: A Practical Guide, ''SAGE Research Method ...
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Irritable Bowel Syndrome
Irritable bowel syndrome (IBS) is a "disorder of gut-brain interaction" characterized by a group of symptoms that commonly include abdominal pain and or abdominal bloating and changes in the consistency of bowel movements. These symptoms may occur over a long time, sometimes for years. IBS can negatively affect quality of life and may result in missed school or work (absenteeism) or reduced productivity at work (presenteeism). Disorders such as anxiety, major depression, and chronic fatigue syndrome are common among people with IBS.The cited review is based on sources ranging from 1988 to 2001 and is probably biased relative to a more recent research. The causes of IBS may well be multi-factorial. Theories include combinations of "gut–brain axis" problems, alterations in gut motility, visceral hypersensitivity, infections including small intestinal bacterial overgrowth, neurotransmitters, genetic factors, and food sensitivity. Onset may be triggered by an intestinal infec ...
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Medical Diagnosis
Medical diagnosis (abbreviated Dx, Dx, or Ds) is the process of determining which disease or condition explains a person's symptoms and signs. It is most often referred to as diagnosis with the medical context being implicit. The information required for diagnosis is typically collected from a history and physical examination of the person seeking medical care. Often, one or more diagnostic procedures, such as medical tests, are also done during the process. Sometimes posthumous diagnosis is considered a kind of medical diagnosis. Diagnosis is often challenging because many signs and symptoms are nonspecific. For example, redness of the skin (erythema), by itself, is a sign of many disorders and thus does not tell the healthcare professional what is wrong. Thus differential diagnosis, in which several possible explanations are compared and contrasted, must be performed. This involves the correlation of various pieces of information followed by the recognition and differentiat ...
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Computer
A computer is a machine that can be programmed to Execution (computing), carry out sequences of arithmetic or logical operations (computation) automatically. Modern digital electronic computers can perform generic sets of operations known as Computer program, programs. These programs enable computers to perform a wide range of tasks. A computer system is a nominally complete computer that includes the Computer hardware, hardware, operating system (main software), and peripheral equipment needed and used for full operation. This term may also refer to a group of computers that are linked and function together, such as a computer network or computer cluster. A broad range of Programmable logic controller, industrial and Consumer electronics, consumer products use computers as control systems. Simple special-purpose devices like microwave ovens and remote controls are included, as are factory devices like industrial robots and computer-aided design, as well as general-purpose devi ...
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Rectum
The rectum is the final straight portion of the large intestine in humans and some other mammals, and the Gastrointestinal tract, gut in others. The adult human rectum is about long, and begins at the rectosigmoid junction (the end of the sigmoid colon) at the level of the third sacral vertebra or the sacral promontory depending upon what definition is used. Its diameter is similar to that of the sigmoid colon at its commencement, but it is dilated near its termination, forming the rectal ampulla. It terminates at the level of the anorectal ring (the level of the puborectalis sling) or the dentate line, again depending upon which definition is used. In humans, the rectum is followed by the anal canal which is about long, before the gastrointestinal tract terminates at the anal verge. The word rectum comes from the Latin ''Wikt:rectum, rectum Wikt:intestinum, intestinum'', meaning ''straight intestine''. Structure The rectum is a part of the lower gastrointestinal tract ...
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Colon (anatomy)
The large intestine, also known as the large bowel, is the last part of the gastrointestinal tract and of the digestive system in tetrapods. Water is absorbed here and the remaining waste material is stored in the rectum as feces before being removed by defecation. The colon is the longest portion of the large intestine, and the terms are often used interchangeably but most sources define the large intestine as the combination of the cecum, colon, rectum, and anal canal. Some other sources exclude the anal canal. In humans, the large intestine begins in the right iliac region of the pelvis, just at or below the waist, where it is joined to the end of the small intestine at the cecum, via the ileocecal valve. It then continues as the colon ascending the abdomen, across the width of the abdominal cavity as the transverse colon, and then descending to the rectum and its endpoint at the anal canal. Overall, in humans, the large intestine is about long, which is about one-fifth o ...
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