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Banff Classification
The Banff Classification is a schema for nomenclature and classification of kidney transplant pathology, established in 1991 by Kim Solez and Lorraine C. Racusen in Banff, Canada. The initiative was "inspired by the then recent development of a consensus grading system for diagnosis of rejection in cardiac allografts led by Dr Margaret Billingham, a key participant at the first Banff transplant pathology meeting". Prior the Banff Classification there was no standardized, international classification for renal allograft biopsies A biopsy is a medical test commonly performed by a surgeon, interventional radiologist, or an interventional cardiologist. The process involves extraction of sample cells or tissues for examination to determine the presence or extent of a diseas ..., which resulted in considerable heterogeneity among pathologists in characterization of renal allograft biopsies. The first Banff schema was published in 1993, and has since undergone updates at regular interval ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Pathology
Pathology is the study of the causes and effects of disease or injury. The word ''pathology'' also refers to the study of disease in general, incorporating a wide range of biology research fields and medical practices. However, when used in the context of modern medical treatment, the term is often used in a narrower fashion to refer to processes and tests that fall within the contemporary medical field of "general pathology", an area which includes a number of distinct but inter-related medical specialties that diagnose disease, mostly through analysis of tissue, cell, and body fluid samples. Idiomatically, "a pathology" may also refer to the predicted or actual progression of particular diseases (as in the statement "the many different forms of cancer have diverse pathologies", in which case a more proper choice of word would be " pathophysiologies"), and the affix ''pathy'' is sometimes used to indicate a state of disease in cases of both physical ailment (as in cardiomy ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Kim Solez
Kim Solez (born 1946) is an American pathologist and co-founder of the Banff Classification, the first standardized international classification for renal allograft biopsies. He is also the founder of the Banff Foundation for Allograft Pathology. Background Kim Solez obtained his M.D. with AOA honours from the University of Rochester School of Medicine and Dentistry, and trained in pathology at Johns Hopkins Medical Institutions in Baltimore, Maryland where he was mentored in renal pathology by Robert Heptinstall. He joined the faculty at Johns Hopkins and in 1987 became chairman of the Department of Pathology at the University of Alberta in Edmonton, Canada. In 1991, he established the Banff Classification, the first standardized, international classification for renal allograft biopsies, with Johns Hopkins pathologist Lorraine Racusen. The Banff Classification, updated in regular intervals, continues to "set standards worldwide for how biopsies from kidney and other solid org ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Banff, Alberta
Banff is a town within Banff National Park in Alberta, Canada. It is located in Alberta's Rockies along the Trans-Canada Highway, approximately west of Calgary and east of Lake Louise. At above Banff is the community with the second highest elevation in Alberta, after Lake Louise. The Town of Banff was the first municipality to incorporate within a Canadian national park. The town is a member of the Calgary Regional Partnership. Banff is a resort town and one of Canada's most popular tourist destinations. Known for its mountainous surroundings and hot springs, it is a destination for outdoor sports and features extensive hiking, biking, scrambling and skiing destinations within the area. Sunshine Village, Ski Norquay and Lake Louise Ski Resort are the three nearby ski resorts located within the national park. Toponymy The area was named Banff in 1884 by George Stephen, president of the Canadian Pacific Railway, recalling his birthplace near Banff, Scotland. The Canadian ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Allografts
Allotransplant (''allo-'' meaning "other" in Greek) is the transplantation of cells, tissues, or organs to a recipient from a genetically non-identical donor of the same species. The transplant is called an allograft, allogeneic transplant, or homograft. Most human tissue and organ transplants are allografts. It is contrasted with autotransplantation (from one part of the body to another in the same person), syngenic transplantation of isografts (grafts transplanted between two genetically identical individuals) and xenotransplantation (from other species). Allografts can be referred to as "homostatic" if they are biologically inert when transplanted, such as bone and cartilage. An immune response against an allograft or xenograft is termed rejection. An allogenic bone marrow transplant can result in an immune attack on the recipient, called graft-versus-host disease. Procedure Material is obtained from a donor who is a living person, or a deceased person's body receiving m ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Margaret Billingham
Margaret E. Billingham (née Macpherson) (September 20, 1930 - July 14, 2009) was a pathologist at Stanford University Medical Center, who made significant achievements in the early recognition and grading of transplant rejection following cardiac transplantation, known as ' Billingham's Criteria'. She also described chronic rejection and techniques in heart endomyocardial biopsy. Born in Tanzania, and educated in Kenya and subsequently qualified from the Royal Free Hospital in London, Billingham found herself developing rejection pathology and eventually becoming director of cardiac pathology at Stanford University Medical Center. She settled in the United States with her husband, who was also a doctor, and their two children, and died there in 2009. Early life Billingham's father was posted as a British diplomat, to Tanzania. She was then born in 1930 in Tanga, Tanzania, and then educated at Loreto School in Kenya. She had a sister, Shirley Anne. Moving to England, she gaine ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Biopsy
A biopsy is a medical test commonly performed by a surgeon, interventional radiologist, or an interventional cardiologist. The process involves extraction of sample cells or tissues for examination to determine the presence or extent of a disease. The tissue is then fixed, dehydrated, embedded, sectioned, stained and mounted before it is generally examined under a microscope by a pathologist; it may also be analyzed chemically. When an entire lump or suspicious area is removed, the procedure is called an excisional biopsy. An incisional biopsy or core biopsy samples a portion of the abnormal tissue without attempting to remove the entire lesion or tumor. When a sample of tissue or fluid is removed with a needle in such a way that cells are removed without preserving the histological architecture of the tissue cells, the procedure is called a needle aspiration biopsy. Biopsies are most commonly performed for insight into possible cancerous or inflammatory conditions. History T ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Banff Foundation For Allograft Pathology
The Banff Foundation for Allograft Pathology also known as the Banff Foundation for Transplant Pathology is a nonprofit Swiss foundation which aims to "lead development and dissemination of the international Banff Classification of Allograft Pathology and to facilitate multidisciplinary, collaborative research to enhance its scientific basis and clinical utility to improve the care of transplant patients". Its predecessor group had organized transplant pathology meetings in every odd numbered year since 1991 and the Foundation has specific future meeting plans through 2025. The meetings establish and maintain the worldwide standards for tissue biopsy reporting and diagnosis of transplant rejection through consensus decision making. They thereby provide an essential service to the field of allotransplantation. The goals of the Banff foundation are to facilitate knowledge generation and translation in transplantation pathology with the ultimate aim of improving patient outcomes, ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Pathology
Pathology is the study of the causes and effects of disease or injury. The word ''pathology'' also refers to the study of disease in general, incorporating a wide range of biology research fields and medical practices. However, when used in the context of modern medical treatment, the term is often used in a narrower fashion to refer to processes and tests that fall within the contemporary medical field of "general pathology", an area which includes a number of distinct but inter-related medical specialties that diagnose disease, mostly through analysis of tissue, cell, and body fluid samples. Idiomatically, "a pathology" may also refer to the predicted or actual progression of particular diseases (as in the statement "the many different forms of cancer have diverse pathologies", in which case a more proper choice of word would be " pathophysiologies"), and the affix ''pathy'' is sometimes used to indicate a state of disease in cases of both physical ailment (as in cardiomy ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
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