Bandicoot Papillomatosis Carcinomatosis Virus
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Bandicoot Papillomatosis Carcinomatosis Virus
Bandicoot papillomatosis carcinomatosis virus is a circular double-stranded DNA virus isolated from bandicoots (''Perameles bougainville''). The genome has features similar to viruses in the families ''Papillomaviridae'' and the ''Polyomaviridae ''Polyomaviridae'' is a family of viruses whose natural hosts are primarily mammals and birds. As of 2020, there are six recognized genera and 117 species, five of which are unassigned to a genus. 14 species are known to infect humans, while othe ...''. Two species have been described to date.Bennett MD, Woolford L, Stevens H, Van Ranst M, Oldfield T, Slaven M, O'Hara AJ, Warren KS, Nicholls PK (2008) Genomic characterization of a novel virus found in papillomatous lesions from a southern brown bandicoot (Isoodon obesulus) in Western Australia. Virology 376(1):173-182 Genome The genome is ~7.5 kilobases in length with a G+C content of ~35%. Two structural genes are present: L1 and L2. The non structural genes are found on the opposite ...
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Virus
A virus is a submicroscopic infectious agent that replicates only inside the living cells of an organism. Viruses infect all life forms, from animals and plants to microorganisms, including bacteria and archaea. Since Dmitri Ivanovsky's 1892 article describing a non-bacterial pathogen infecting tobacco plants and the discovery of the tobacco mosaic virus by Martinus Beijerinck in 1898,Dimmock p. 4 more than 9,000 virus species have been described in detail of the millions of types of viruses in the environment. Viruses are found in almost every ecosystem on Earth and are the most numerous type of biological entity. The study of viruses is known as virology, a subspeciality of microbiology. When infected, a host cell is often forced to rapidly produce thousands of copies of the original virus. When not inside an infected cell or in the process of infecting a cell, viruses exist in the form of independent particles, or ''virions'', consisting of (i) the genetic material, i. ...
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Perameles Bougainville
The Western barred bandicoot (''Perameles bougainville''), also known as the Marl, is a small species of bandicoot; now extinct across most of its former range, the western barred bandicoot only survives on offshore islands and in fenced sanctuaries on the mainland. Description The Western barred bandicoot Is much smaller than its relative the eastern barred bandicoot (''Perameles gunnii''), and is darker in its colouring, which is a grizzled brown. It measures about in length. It has two "bars" across its rump and has a short, tapered tail. It was a solitary and crepuscular hunter, eating insects, spiders, and worms and occasionally tubers and roots. When the bandicoot feels threatened, it typically leaps into the air and then burrows to safety. Taxonomy The first description of the Western barred bandicoot was from a specimen taken at Peron Peninsula in 1817 by naturalists on the ''Uranie''. Populations of the ''Perameles'' species have been referred to by various names, ...
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Papillomaviridae
''Papillomaviridae'' is a family of non- enveloped DNA viruses whose members are known as papillomaviruses. Several hundred species of papillomaviruses, traditionally referred to as "types", have been identified infecting all carefully inspected mammals, but also other vertebrates such as birds, snakes, turtles and fish. Infection by most papillomavirus types, depending on the type, is either asymptomatic (e.g. most Beta-PVs) or causes small benign tumors, known as papillomas or warts (e.g. human papillomavirus 1, HPV6 or HPV11). Papillomas caused by some types, however, such as human papillomaviruses 16 and 18, carry a risk of becoming cancerous. Papillomaviruses are usually considered as highly host- and tissue-tropic, and are thought to rarely be transmitted between species. Papillomaviruses replicate exclusively in the basal layer of the body surface tissues. All known papillomavirus types infect a particular body surface, typically the skin or mucosal epithelium of the gen ...
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Polyomaviridae
''Polyomaviridae'' is a family of viruses whose natural host (biology), hosts are primarily mammals and birds. As of 2020, there are six recognized genera and 117 species, five of which are unassigned to a genus. 14 species are known to infect humans, while others, such as Simian Virus 40, have been identified in humans to a lesser extent. Most of these viruses are very common and typically asymptomatic in most human populations studied. BK virus is associated with nephropathy in renal transplant and non-renal solid organ transplant patients, JC virus with progressive multifocal leukoencephalopathy, and Merkel cell virus with Merkel cell cancer. Structure and genome Polyomaviruses are viral envelope, non-enveloped double-stranded DNA viruses with circular genomes of around 5000 base pairs. The genome is packaged in a viral capsid of about 40-50 nanometers in diameter, which is icosahedral in shape (T=7 symmetry). The capsid is composed of 72 pentameric capsomeres of a protein ca ...
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