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Baltimore Underground Science Space
The Baltimore Underground Science Space (BUGSS) is a non-profit synthetic biology and biotechnology makerspace laboratory for science enthusiasts, hobbyists, and professionals to practice, share and learn about the biological sciences. BUGSS is closely aligned with do-it-yourself biology and the Maryland science community generally, and offers courses and lectures in addition to community lab space. It was founded by Dr. Tom Burkett in 2012. It is located in the Highlandtown neighborhood of Baltimore, Maryland. BUGSS has regularly hosted teams for the annual International Genetically Engineered Machine (iGEM) competition. In 2014, the team focused on 3D bioprinting. In 2016, the team worked on isolating the genes in the bacterium ''Ideonella sakaiensis'' that allow it to consume the plastic PET, and introducing them into ''Escherichia coli ''Escherichia coli'' (),Wells, J. C. (2000) Longman Pronunciation Dictionary. Harlow ngland Pearson Education Ltd. also known as ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Synthetic Biology
Synthetic biology (SynBio) is a multidisciplinary area of research that seeks to create new biological parts, devices, and systems, or to redesign systems that are already found in nature. It is a branch of science that encompasses a broad range of methodologies from various disciplines, such as biotechnology, biomaterials, material science/engineering, genetic engineering, molecular biology, molecular engineering, systems biology, membrane science, biophysics, chemical and biological engineering, electrical and computer engineering, control engineering and evolutionary biology. Due to more powerful genetic engineering capabilities and decreased DNA synthesis and sequencing costs, the field of synthetic biology is rapidly growing. In 2016, more than 350 companies across 40 countries were actively engaged in synthetic biology applications; all these companies had an estimated net worth of $3.9 billion in the global market. Definition Synthetic biology currently has no gen ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Biotechnology
Biotechnology is the integration of natural sciences and engineering sciences in order to achieve the application of organisms, cells, parts thereof and molecular analogues for products and services. The term ''biotechnology'' was first used by Károly Ereky in 1919, meaning the production of products from raw materials with the aid of living organisms. Definition The concept of biotechnology encompasses a wide range of procedures for modifying living organisms according to human purposes, going back to domestication of animals, cultivation of the plants, and "improvements" to these through breeding programs that employ artificial selection and hybridization. Modern usage also includes genetic engineering as well as cell and tissue culture technologies. The American Chemical Society defines biotechnology as the application of biological organisms, systems, or processes by various industries to learning about the science of life and the improvement of the value of materials ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Makerspace
A hackerspace (also referred to as a hacklab, hackspace, or makerspace) is a community-operated, often "not for profit" (501(c)(3) in the United States), workspace where people with common interests, such as computers, machining, technology, science, digital art, or electronic art, can meet, socialize, and collaborate. Hackerspaces are comparable to other community-operated spaces with similar aims and mechanisms such as Fab Lab, men's sheds, and commercial "for-profit" companies. History Hackerspaces with open membership became common throughout Germany in the 1990s in the orbit of the German Chaos Computer Club (CCC), with the c-base being probably an example. The concept, however, was limited to less than a dozen spaces within Germany, and did not spread beyond borders at first. Most likely this was because initial founding costs were prohibitive for small groups without the support of a large organization like the CCC. From 1997, Chicago's Autonomous Zone Infoshop hosted " ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Do-it-yourself Biology
Do-it-yourself biology (DIY biology, DIY bio) is a growing biotechnology, biotechnological social movement in which individuals, communities, and small organizations study biology and List of life sciences, life science using the same methods as traditional research institutions. Do it yourself, DIY biology is primarily undertaken by individuals with limited research training from academia or corporations, who then mentor and oversee other DIY biologists with little or no formal training. This may be done as a hobby, as a not-for-profit endeavour for community learning and open-science innovation, or for profit, to start a business. Other terms are also associated with the do-it-yourself biology community. The terms biohacking and wetware hacking emphasize the connection to hacker culture and the hacker ethic. The term hacker is used in the original sense of finding new and clever ways to do things. The term biohacking is also used by the Grinder (biohacking community), grinder b ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Highlandtown, Baltimore
Highlandtown is a neighborhood of Baltimore, Maryland, United States. Description and history The area currently known as Highlandtown was established in 1866 when the area known as "Snake Hill" was established as a village outside the Baltimore city limits. The first settlers of the community were primarily German Americans. In 1870, residents renamed the neighborhood "Highland Town" because of the views it offered over the city. The neighborhood was made part of Baltimore City in 1919. The neighborhood today is bounded by Haven Street to the east, Baltimore Street to the north, Linwood Avenue to the west, and Eastern Avenue to the south. The long stretch of Eastern Avenue that runs through the neighborhood is notable as the Highlandtown's main commercial thoroughfare. The area was designated as a "Main Street District" by a previous mayor Martin O'Malley, seeking to promote commercial revitalization through economic incentives from the National Main Street Program. Highl ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Baltimore
Baltimore ( , locally: or ) is the most populous city in the U.S. state of Maryland, fourth most populous city in the Mid-Atlantic, and the 30th most populous city in the United States with a population of 585,708 in 2020. Baltimore was designated an independent city by the Constitution of Maryland in 1851, and today is the most populous independent city in the United States. As of 2021, the population of the Baltimore metropolitan area was estimated to be 2,838,327, making it the 20th largest metropolitan area in the country. Baltimore is located about north northeast of Washington, D.C., making it a principal city in the Washington–Baltimore combined statistical area (CSA), the third-largest CSA in the nation, with a 2021 estimated population of 9,946,526. Prior to European colonization, the Baltimore region was used as hunting grounds by the Susquehannock Native Americans, who were primarily settled further northwest than where the city was later built. Colonist ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Maryland
Maryland ( ) is a state in the Mid-Atlantic region of the United States. It shares borders with Virginia, West Virginia, and the District of Columbia to its south and west; Pennsylvania to its north; and Delaware and the Atlantic Ocean to its east. Baltimore is the largest city in the state, and the capital is Annapolis. Among its occasional nicknames are '' Old Line State'', the ''Free State'', and the '' Chesapeake Bay State''. It is named after Henrietta Maria, the French-born queen of England, Scotland, and Ireland, who was known then in England as Mary. Before its coastline was explored by Europeans in the 16th century, Maryland was inhabited by several groups of Native Americans – mostly by Algonquian peoples and, to a lesser degree, Iroquoian and Siouan. As one of the original Thirteen Colonies of England, Maryland was founded by George Calvert, 1st Baron Baltimore, a Catholic convert"George Calvert and Cecilius Calvert, Barons Baltimore" William Hand Browne, ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
International Genetically Engineered Machine
The International Genetically Engineered Machine (iGEM) competition is a worldwide synthetic biology competition that was initially aimed at undergraduate university students, but has since expanded to include divisions for high school students, entrepreneurs, and community laboratories, as well as 'overgraduates'. Competition details Student teams are given a kit (so called ‘Distribution Kit’) of standard, interchangeable parts (so called 'BioBricks') at the beginning of the summer from the Registry of Standard Biological Parts comprising various genetic components such as promoters, terminators, reporter elements, and plasmid backbones. Working at their local laboratories over the summer, they use these parts and new parts of their own design to build biological systems and operate them in living cells. The teams are free to choose a project, which can build on previous projects or be new to iGEM. Successful projects produce cells that exhibit new and unusual propert ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
3D Bioprinting
Three dimensional (3D) bioprinting is the utilization of 3D printing–like techniques to combine cells, growth factors, and/or biomaterials to fabricate biomedical parts, often with the aim of imitating natural tissue characteristics. Generally, 3D bioprinting can utilize a layer-by-layer method to deposit materials known as Bio-ink, bio-inks to create tissue-like structures that are later used in various medical and tissue engineering fields. 3D bioprinting covers a broad range of bioprinting techniques and biomaterials. Currently, bioprinting can be used to print tissue and organ models to help research drugs and potential treatments. Nonetheless, translation of bioprinted living cellular constructs into clinical application is met with several issues due to the complexity and cell number needed to create functional organs. However, innovations span from bioprinting of extracellular matrix to mixing cells with Hydrogel, hydrogels deposited layer by layer to produce the desired tis ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Ideonella Sakaiensis
''Ideonella sakaiensis'' is a bacterium from the genus'' Ideonella'' and family Comamonadaceae capable of breaking down and consuming the plastic polyethylene terephthalate (PET) using it as both a carbon and energy source. The bacterium was originally isolated from a sediment sample taken outside of a plastic bottle recycling facility in Sakai City, Japan. * Discovery ''Ideonella sakaiensis'' was first identified in 2016 by a team of researchers led by Kohei Oda of Kyoto Institute of Technology and Kenji Miyamoto of Keio University after collecting a sample of PET-contaminated sediment at a plastic bottle recycling facility in Sakai, Japan. The bacteria was first isolated from a consortium of microorganisms in the sediment sample, which included protozoa and yeast-like cells. The entire microbial community was shown to mineralize 75% of the degraded PET into carbon dioxide once it had been initially degraded and assimilated by ''Ideonella sakaiensis''. Characterization Phys ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Polyethylene Terephthalate
Polyethylene terephthalate (or poly(ethylene terephthalate), PET, PETE, or the obsolete PETP or PET-P), is the most common thermoplastic polymer resin of the polyester family and is used in fibres for clothing, containers for liquids and foods, and thermoforming for manufacturing, and in combination with glass fibre for engineering resins. In 2016, annual production of PET was 56 million tons. The biggest application is in fibres (in excess of 60%), with bottle production accounting for about 30% of global demand. In the context of textile applications, PET is referred to by its common name, polyester, whereas the acronym ''PET'' is generally used in relation to packaging. Polyester makes up about 18% of world polymer production and is the fourth-most-produced polymer after polyethylene (PE), polypropylene (PP) and polyvinyl chloride (PVC). PET consists of repeating (C10H8O4) units. PET is commonly recycled, and has the digit 1 (♳) as its resin identification code (RIC). T ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Escherichia Coli
''Escherichia coli'' (),Wells, J. C. (2000) Longman Pronunciation Dictionary. Harlow ngland Pearson Education Ltd. also known as ''E. coli'' (), is a Gram-negative, facultative anaerobic, rod-shaped, coliform bacterium of the genus ''Escherichia'' that is commonly found in the lower intestine of warm-blooded organisms. Most ''E. coli'' strains are harmless, but some serotypes ( EPEC, ETEC etc.) can cause serious food poisoning in their hosts, and are occasionally responsible for food contamination incidents that prompt product recalls. Most strains do not cause disease in humans and are part of the normal microbiota of the gut; such strains are harmless or even beneficial to humans (although these strains tend to be less studied than the pathogenic ones). For example, some strains of ''E. coli'' benefit their hosts by producing vitamin K2 or by preventing the colonization of the intestine by pathogenic bacteria. These mutually beneficial relationships between ''E. col ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
