Bryan Roth
Bryan L. Roth is the Michael Hooker Distinguished Professor of Protein Therapeutics and Translational Proteomics, University of North Carolina School of Medicine. He is recognized for his discoveries and inventions in the general areas of molecular pharmacology, GPCR structure, and function and synthetic neurobiology. He is a member of the American Academy of Arts and Sciences (AAAS) and the National Academy of Medicine of the National Academy of Sciences (NAM) Education Roth earned his B.A. in biology from Carroll College in 1977 and his M.D. and Ph.D. in biochemistry from Saint Louis University in 1983. After postdoctoral training at the National Institute of Mental Health (NIMH), he completed a psychiatry residency and fellowship at Stanford University in 1991. In 2007 he was appointed as the Michael Hooker Distinguished Professor of Protein Therapeutics and Translational Proteomics, UNC School of Medicine. Research Roth has made contributions to the fields of G ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Chemogenetic
Chemogenetics is the process by which macromolecules can be engineered to interact with previously unrecognized small molecules. Chemogenetics as a term was originally coined to describe the observed effects of mutations on chalcone isomerase activity on substrate specificities in the flowers of ''Dianthus caryophyllus''. This method is very similar to optogenetics; however, it uses chemically engineered molecules and ligands instead of light and light-sensitive channels known as opsins. In recent research projects, chemogenetics has been widely used to understand the relationship between brain activity and behavior. Prior to chemogenetics, researchers used methods such as transcranial magnetic stimulation and deep brain stimulation to study the relationship between neuronal activity and behavior. Comparison to optogenetics Optogenetics and chemogenetics are the more recent and popular methods used to study this relationship. Both of these methods target specific brain circuits a ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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University Of North Carolina Faculty
A university () is an institution of higher (or tertiary) education and research which awards academic degrees in several academic disciplines. ''University'' is derived from the Latin phrase ''universitas magistrorum et scholarium'', which roughly means "community of teachers and scholars". Universities typically offer both undergraduate and postgraduate programs. The first universities in Europe were established by Catholic Church monks. The University of Bologna (), Italy, which was founded in 1088, is the first university in the sense of: *being a high degree-awarding institute. *using the word ''universitas'' (which was coined at its foundation). *having independence from the ecclesiastic schools and issuing secular as well as non-secular degrees (with teaching conducted by both clergy and non-clergy): grammar, rhetoric, logic, theology, canon law, notarial law.Hunt Janin: "The university in medieval life, 1179–1499", McFarland, 2008, , p. 55f.de Ridder-Symoens, Hilde' ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Carroll College (Montana) Alumni
Carroll College is a private Catholic college in Helena, Montana. The college has 21 buildings on a 63-acre campus, has over 35 academic majors, participates in 15 NAIA athletic sports, and is home to All Saints Chapel. The college motto, in Latin, is ''“Non scholae, sed vitae.”'' The college translates this into English as “Not for school, but for life.” Carroll's colors are purple and gold and the school's athletics teams are known as the Fighting Saints. History In 1883, the first bishop of Helena, John Baptist Brondel, proposed a Catholic college in Montana to help produce future priests for the soon-to-be diocese of Helena. He died before his plans could be realized. Pope Pius X selected John Patrick Carroll, a young priest from Dubuque, Iowa, as Brondel's successor. Bishop John Patrick Carroll, second Bishop of the Diocese of Helena, was able to carve out the funding needed to launch the college while at the same time raising money to construct the Cathedral o ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Saint Louis University Alumni
In religious belief, a saint is a person who is recognized as having an exceptional degree of holiness, likeness, or closeness to God. However, the use of the term ''saint'' depends on the context and denomination. In Catholic, Eastern Orthodox, Anglican, Oriental Orthodox, and Lutheran doctrine, all of their faithful deceased in Heaven are considered to be saints, but some are considered worthy of greater honor or emulation. Official ecclesiastical recognition, and consequently a public cult of veneration, is conferred on some denominational saints through the process of canonization in the Catholic Church or glorification in the Eastern Orthodox Church after their approval. While the English word ''saint'' originated in Christianity, historians of religion tend to use the appellation "in a more general way to refer to the state of special holiness that many religions attribute to certain people", referring to the Jewish tzadik, the Islamic walī, the Hindu rishi or Sikh ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Living People
Related categories * :Year of birth missing (living people) / :Year of birth unknown * :Date of birth missing (living people) / :Date of birth unknown * :Place of birth missing (living people) / :Place of birth unknown * :Year of death missing / :Year of death unknown * :Date of death missing / :Date of death unknown * :Place of death missing / :Place of death unknown * :Missing middle or first names See also * :Dead people * :Template:L, which generates this category or death years, and birth year and sort keys. : {{DEFAULTSORT:Living people 21st-century people People by status ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Year Of Birth Missing (living People)
A year or annus is the orbital period of a planetary body, for example, the Earth, moving in its orbit around the Sun. Due to the Earth's axial tilt, the course of a year sees the passing of the seasons, marked by change in weather, the hours of daylight, and, consequently, vegetation and soil fertility. In temperate and subpolar regions around the planet, four seasons are generally recognized: spring, summer, autumn and winter. In tropical and subtropical regions, several geographical sectors do not present defined seasons; but in the seasonal tropics, the annual wet and dry seasons are recognized and tracked. A calendar year is an approximation of the number of days of the Earth's orbital period, as counted in a given calendar. The Gregorian calendar, or modern calendar, presents its calendar year to be either a common year of 365 days or a leap year of 366 days, as do the Julian calendars. For the Gregorian calendar, the average length of the calendar yea ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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American Society For Pharmacology And Experimental Therapeutics
The American Society for Pharmacology and Experimental Therapeutics (ASPET) is a scientific society founded in late 1908 by John Jacob Abel of Johns Hopkins University (also the founder of the American Society for Biochemistry and Molecular Biology), with the aim of promoting the growth of pharmacological research. Many society members are researchers in basic and clinical pharmacology who help develop disease-fighting medications and therapeutics. ASPET is one of the constituent societies of the Federation of American Societies for Experimental Biology (FASEB). The society's headquarters are in Rockville, MD. The current president is Michael F. Jarvis. Publications The society publishes three research journals and a review journal: the ''Journal of Pharmacology and Experimental Therapeutics'', ''Drug Metabolism and Disposition'', ''Molecular Pharmacology'', and '' Pharmacological Reviews'' Starting in 2012 these publications are only offered online. The society copublishes a w ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Nature Chemical Biology
''Nature Chemical Biology'' is a monthly peer-reviewed scientific journal published by Nature Portfolio. It was established in June 2005. Terry L. Sheppard is a full-time professional editor with the title, "Chief Editor", and employed by ''Nature Chemical Biology''. Aims and scope The publishing focus of ''Nature Chemical Biology'' is a forum for original research and commentary in chemical biology. Published topics encompass concepts and research methods in chemistry, biology, and related disciplines with the end result of controlling biological systems at the molecular level. Authors (contributors) are chemical biologists, also chemists involved in interdisciplinary research between chemistry and biology, along with biologists who produce research results in understanding and controlling biological processes at the molecular level. Interdisciplinary research in chemistry and biology is emphasized. The journal's main focus in this area is fundamental research which illumin ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Science Signaling
''Science Signaling'' is a peer-reviewed scientific journal that is focused on cell signaling and regulation. It is published weekly by the American Association for the Advancement of Science (AAAS). The editor-in-chief (Chief Scientific Editor) is Michael B. Yaffe (Massachusetts Institute of Technology), and the journal is part of thScience Family of Journalsof which Holden Thorp is the Editor-in-Chief. Scope The journal covers research on cell signaling and the processes of cellular regulation. In addition, the journal covers signaling networks, synthetic biology, systems biology, drug discovery, and computation and modeling of regulatory pathways. Besides full length articles, it also publishes reviews, perspectives, meeting reports, presentations (for a wider audience), protocols, book reviews, teaching resources, a glossary, and a Journal Club section. History The journal was established in 1999 as ''Science's STKE''. On January 8, 2008, it obtained its current name and ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Brain Initiative
The White House BRAIN Initiative (Brain Research through Advancing Innovative Neurotechnologies) is a collaborative, public-private research initiative announced by the Obama administration on April 2, 2013, with the goal of supporting the development and application of innovative technologies that can create a dynamic understanding of brain function. This activity is a Grand Challenge focused on revolutionizing our understanding of the human brain, and was developed by the White House Office of Science and Technology Policy (OSTP) as part of a broader White House Neuroscience Initiative. Inspired by the Human Genome Project, BRAIN aims to help researchers uncover the mysteries of brain disorders, such as Alzheimer's and Parkinson's diseases, depression, and traumatic brain injury (TBI). Participants in BRAIN and affiliates of the project include DARPA and IARPA as well as numerous private companies, universities, and other organizations in the United States, Australia, Cana ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Thomas Insel
Thomas Roland Insel (born October 19, 1951) is an American neuroscientist, psychiatrist, entrepreneur, and author who led the National Institute of Mental Health (NIMH) from 2002 until November 2015. Prior to becoming Director of NIMH, he was the founding Director of the Center for Behavioral Neuroscience at Emory University in Atlanta, Georgia. He is best known for research on oxytocin and vasopressin, two peptide hormones implicated in complex social behaviors, such as parental care and attachment. He announced on Sept. 15, 2015, that he was resigning as the director of the NIMH to join the Life Science division of Google X (now Verily Life Sciences). On May 8, 2017, CNBC reported that he had left Verily Life Sciences. Insel is a Co-founder with Richard Klausner and Paul Dagum of a digital mental health company named "Mindstrong," a Bay-area startup. He has also co-founded Humanest Care, NeuraWell Therapeutics, and MindSite News and is a member of the scientific advisory ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |