Benedita Barata Da Rocha
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Benedita Barata Da Rocha
Benedita Barata da Rocha (24 February 1949 – 2 October 2021) was a Portuguese immunology, immunologist. She earned her M.D. 1972 from the University of Lisbon, and her Ph.D. 1978 from the University of Glasgow, Scotland, UK. She was "directeur de recherche classe exceptionel" (DRCE) of the CNRS and director of a research unit of the INSERM at the Necker Institute, Paris, France. Her major scientific contributions are in the areas of T cell immune tolerance, T cell memory and development of intraepithelial lymphocytes. In 2007 she received the CNRS Silver Medal award and in 2009 a European Research Council advanced grant. She published more than 100 research articles. Major works * * * * References

1949 births 2021 deaths People from Lisbon Portuguese immunologists University of Lisbon alumni Alumni of the University of Glasgow Research directors of the French National Centre for Scientific Research {{Immunology-stub ...
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Immunology
Immunology is a branch of medicineImmunology for Medical Students, Roderick Nairn, Matthew Helbert, Mosby, 2007 and biology that covers the medical study of immune systems in humans, animals, plants and sapient species. In such we can see there is a difference of human immunology and comparative immunology in veterinary medicine and animal biosciences. Immunology measures, uses charts and differentiate in context in medicine the studies of immunity on cell and molecular level, and the immune system as part of the physiological level as its functioning is of major importance. In the different states of both health, occurring symptoms and diseases; the functioning of the immune system and immunological responses such as autoimmune diseases, allergic hypersensitivities, or in some cases malfunctioning of immune system as for example in immunological disorders or in immune deficiency, and the specific transplant rejection) Immunology has applications in numerous disciplines of ...
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Intraepithelial Lymphocytes
Intraepithelial lymphocytes (IEL) are lymphocytes found in the epithelial layer of mammalian mucosal linings, such as the gastrointestinal (GI) tract and reproductive tract. However, unlike other T cells, IELs do not need priming. Upon encountering antigens, they immediately release cytokines and cause killing of infected target cells. In the GI tract, they are components of gut-associated lymphoid tissue (GALT). Intestinal IELs are long-lived resistant effector cells spread along the entire length of intestine, where they patrol the space between intestinal epithelial cells (IEC) and the basement membrane (the intraepithelial space). Epithelium of small intestine contains approximately 1 IEL per 10 enterocytes. Due to their constant exposure to of antigens at mucosal barrier, they have unique antigen-experienced activated phenotypes and they constantly express CD103 (αE integrin), that is distinct from the conventional T cells in the intestine. IELs are mainly T cells with mixtur ...
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University Of Lisbon Alumni
A university () is an educational institution, institution of higher education, higher (or Tertiary education, tertiary) education and research which awards academic degrees in several Discipline (academia), academic disciplines. Universities typically offer both undergraduate education, undergraduate and postgraduate education, postgraduate programs. In the United States, the designation is reserved for colleges that have a graduate school. The word ''university'' is derived from the Latin ''universitas magistrorum et scholarium'', which roughly means "community of teachers and scholars". The first universities were created in Europe by Catholic Church monks. The University of Bologna (''Università di Bologna''), founded in 1088, is the first university in the sense of: *Being a high degree-awarding institute. *Having independence from the ecclesiastic schools, although conducted by both clergy and non-clergy. *Using the word ''universitas'' (which was coined at its foundation ...
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Portuguese Immunologists
Portuguese may refer to: * anything of, from, or related to the country and nation of Portugal ** Portuguese cuisine, traditional foods ** Portuguese language, a Romance language *** Portuguese dialects, variants of the Portuguese language ** Portuguese man o' war, a dangerous marine cnidarian that resembles an 18th-century armed sailing ship ** Portuguese people, an ethnic group See also * * '' Sonnets from the Portuguese'' * "A Portuguesa", the national anthem of Portugal * Lusofonia * Lusitania Lusitania (; ) was an ancient Iberian Roman province located where modern Portugal (south of the Douro river) and a portion of western Spain (the present Extremadura and the province of Salamanca) lie. It was named after the Lusitani or Lusita ... * {{disambiguation Language and nationality disambiguation pages ...
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People From Lisbon
A person ( : people) is a being that has certain capacities or attributes such as reason, morality, consciousness or self-consciousness, and being a part of a culturally established form of social relations such as kinship, ownership of property, or legal responsibility. The defining features of personhood and, consequently, what makes a person count as a person, differ widely among cultures and contexts. In addition to the question of personhood, of what makes a being count as a person to begin with, there are further questions about personal identity and self: both about what makes any particular person that particular person instead of another, and about what makes a person at one time the same person as they were or will be at another time despite any intervening changes. The plural form "people" is often used to refer to an entire nation or ethnic group (as in "a people"), and this was the original meaning of the word; it subsequently acquired its use as a plural form of per ...
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2021 Deaths
This is a list of deaths of notable people, organised by year. New deaths articles are added to their respective month (e.g., Deaths in ) and then linked here. 2022 2021 2020 2019 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 2008 2007 2006 2005 2004 2003 2002 2001 2000 1999 1998 1997 1996 1995 1994 1993 1992 1991 1990 1989 1988 1987 See also * Lists of deaths by day The following pages, corresponding to the Gregorian calendar, list the historical events, births, deaths, and holidays and observances of the specified day of the year: Footnotes See also * Leap year * List of calendars * List of non-standard ... * Deaths by year {{DEFAULTSORT:deaths by year ...
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1949 Births
Events January * January 1 – A United Nations-sponsored ceasefire brings an end to the Indo-Pakistani War of 1947. The war results in a stalemate and the division of Kashmir, which still continues as of 2022. * January 2 – Luis Muñoz Marín becomes the first democratically elected Governor of Puerto Rico. * January 11 – The first "networked" television broadcasts take place, as KDKA-TV in Pittsburgh, Pennsylvania goes on the air, connecting east coast and mid-west programming in the United States. * January 16 – Şemsettin Günaltay forms the new government of Turkey. It is the 18th government, last One-party state, single party government of the Republican People's Party. * January 17 – The first Volkswagen Beetle, VW Type 1 to arrive in the United States, a 1948 model, is brought to New York City, New York by Dutch businessman Ben Pon Sr., Ben Pon. Unable to interest dealers or importers in the Volkswagen, Pon sells the sample car to pay his ...
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European Research Council
The European Research Council (ERC) is a public body for funding of scientific and technological research conducted within the European Union (EU). Established by the European Commission in 2007, the ERC is composed of an independent Scientific Council, its governing body consisting of distinguished researchers, and an Executive Agency, in charge of the implementation. It forms part of the framework programme of the union dedicated to research and innovation, Horizon 2020, preceded by the Seventh Research Framework Programme (FP7). The ERC budget is over €13 billion from 2014 – 2020 and comes from the Horizon 2020 programme, a part of the European Union's budget. Under Horizon 2020 it is estimated that around 7,000 ERC grantees will be funded and 42,000 team members supported, including 11,000 doctoral students and almost 16,000 post-doctoral researchers. Researchers from any field can compete for the grants that support pioneering projects. The ERC competitions are open ...
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CNRS Silver Medal
The CNRS Silver Medal is a scientific award given every year to about fifteen researchers by the French National Centre for Scientific Research The French National Centre for Scientific Research (french: link=no, Centre national de la recherche scientifique, CNRS) is the French state research organisation and is the largest fundamental science agency in Europe. In 2016, it employed 31,63 ... (CNRS). It is awarded to a researcher for "the originality, quality and importance of their work, recognised on a national and international level". It is part of the "CNRS Talents" medals, along with the CNRS gold medal, which rewards a whole scientific career, the CNRS bronze medal, which rewards young researchers, the Innovation medal, which honours remarkable work in the technological, therapeutic, economic or societal fields, and the CNRS Crystal medal, which rewards research support staff. Notable recipients * Gabriel Peyré (mathematics) (2021) * Marie-Hélène Verlhac (biol ...
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T Cell Memory
T, or t, is the twentieth letter in the Latin alphabet, used in the modern English alphabet, the alphabets of other western European languages and others worldwide. Its name in English is ''tee'' (pronounced ), plural ''tees''. It is derived from the Semitic Taw 𐤕 of the Phoenician and Paleo-Hebrew script ( Aramaic and Hebrew Taw ת/𐡕/, Syriac Taw ܬ, and Arabic ت Tāʼ) via the Greek letter τ ( tau). In English, it is most commonly used to represent the voiceless alveolar plosive, a sound it also denotes in the International Phonetic Alphabet. It is the most commonly used consonant and the second most commonly used letter in English-language texts. History ''Taw'' was the last letter of the Western Semitic and Hebrew alphabets. The sound value of Semitic ''Taw'', Greek alphabet Tαυ (''Tau''), Old Italic and Latin T has remained fairly constant, representing in each of these; and it has also kept its original basic shape in most of these alphabets. ...
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Público (Portugal)
''Público'' (; English: ''Public'') is a Portuguese daily national newspaper of record published in Lisbon, Portugal. History and profile ''Público'' was first published on 5 March 1990. The paper was founded by Sonae and is owned by the Sonae group. In 1992 Italian media company Repubblica International Holding SA, a subsidiary of Gruppo Editoriale L'Espresso, acquired 16.75% of the paper. ''Público'' is published in tabloid format and has its headquarters in Lisbon. The paper is known as a publication of the French school with extensive texts and few illustrations. Its first editor-in-chief was Vicente Jorge Silva, formerly sub-editor-in-chief at ''Expresso''. José Manuel Fernandes also served as the editor-in-chief of the paper. Since 2009 Bárbara Reis has served as the editor-in-chief. ''Público'' is one of the first Portuguese mainstream newspapers to have an online edition which was started in 1995. Its online edition was free and included almost all the articles fr ...
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Immune Tolerance
Immune tolerance, or immunological tolerance, or immunotolerance, is a state of unresponsiveness of the immune system to substances or tissue that would otherwise have the capacity to elicit an immune response in a given organism. It is induced by prior exposure to that specific antigen and contrasts with conventional immune-mediated elimination of foreign antigens (see Immune response). Tolerance is classified into central tolerance or peripheral tolerance depending on where the state is originally induced—in the thymus and bone marrow (central) or in other tissues and lymph nodes (peripheral). The mechanisms by which these forms of tolerance are established are distinct, but the resulting effect is similar. Immune tolerance is important for normal physiology. Central tolerance is the main way the immune system learns to discriminate self from non-self. Peripheral tolerance is key to preventing over-reactivity of the immune system to various environmental entities (allergens, g ...
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