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Bayesian Survival Analysis
Survival analysis is normally carried out using parametric models, semi-parametric models, non-parametric model Nonparametric statistics is the branch of statistics that is not based solely on parametrized families of probability distributions (common examples of parameters are the mean and variance). Nonparametric statistics is based on either being distri ...s to estimate the survival rate in clinical research. However recently Bayesian models are also used to estimate the survival rate due to their ability to handle design and analysis issues in clinical research. References Bayesian statistics Survival analysis {{statistics-stub ...
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Survival Analysis
Survival analysis is a branch of statistics for analyzing the expected duration of time until one event occurs, such as death in biological organisms and failure in mechanical systems. This topic is called reliability theory or reliability analysis in engineering, duration analysis or duration modelling in economics, and event history analysis in sociology. Survival analysis attempts to answer certain questions, such as what is the proportion of a population which will survive past a certain time? Of those that survive, at what rate will they die or fail? Can multiple causes of death or failure be taken into account? How do particular circumstances or characteristics increase or decrease the probability of survival? To answer such questions, it is necessary to define "lifetime". In the case of biological survival, death is unambiguous, but for mechanical reliability, failure may not be well-defined, for there may well be mechanical systems in which failure is partial, a matter of ...
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Parametric Model
In statistics, a parametric model or parametric family or finite-dimensional model is a particular class of statistical models. Specifically, a parametric model is a family of probability distributions that has a finite number of parameters. Definition A statistical model is a collection of probability distributions on some sample space. We assume that the collection, , is indexed by some set . The set is called the parameter set or, more commonly, the parameter space. For each , let denote the corresponding member of the collection; so is a cumulative distribution function. Then a statistical model can be written as : \mathcal = \big\. The model is a parametric model if for some positive integer . When the model consists of absolutely continuous distributions, it is often specified in terms of corresponding probability density functions: : \mathcal = \big\. Examples * The Poisson family of distributions is parametrized by a single number : : \m ...
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Semiparametric Model
In statistics, a semiparametric model is a statistical model that has parametric and nonparametric components. A statistical model is a parameterized family of distributions: \ indexed by a parameter \theta. * A parametric model is a model in which the indexing parameter \theta is a vector in k-dimensional Euclidean space, for some nonnegative integer k.. Thus, \theta is finite-dimensional, and \Theta \subseteq \mathbb^k. * With a nonparametric model, the set of possible values of the parameter \theta is a subset of some space V, which is not necessarily finite-dimensional. For example, we might consider the set of all distributions with mean 0. Such spaces are vector spaces with topological structure, but may not be finite-dimensional as vector spaces. Thus, \Theta \subseteq V for some possibly infinite-dimensional space V. * With a semiparametric model, the parameter has both a finite-dimensional component and an infinite-dimensional component (often a real-valued functi ...
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Non-parametric Model
Nonparametric statistics is the branch of statistics that is not based solely on parametrized families of probability distributions (common examples of parameters are the mean and variance). Nonparametric statistics is based on either being distribution-free or having a specified distribution but with the distribution's parameters unspecified. Nonparametric statistics includes both descriptive statistics and statistical inference. Nonparametric tests are often used when the assumptions of parametric tests are violated. Definitions The term "nonparametric statistics" has been imprecisely defined in the following two ways, among others: Applications and purpose Non-parametric methods are widely used for studying populations that take on a ranked order (such as movie reviews receiving one to four stars). The use of non-parametric methods may be necessary when data have a ranking but no clear numerical interpretation, such as when assessing preferences. In terms of levels of meas ...
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Survival Rate
Survival rate is a part of survival analysis. It is the proportion of people in a study or treatment group still alive at a given period of time after diagnosis. It is a method of describing prognosis in certain disease conditions, and can be used for the assessment of standards of therapy. The survival period is usually reckoned from date of diagnosis or start of treatment. Survival rates are based on the population as a whole and cannot be applied directly to an individual. There are various types of survival rates (discussed below). They often serve as endpoints of clinical trials and should not be confused with mortality rates, a population metric. Overall survival Patients with a certain disease (for example, colorectal cancer) can die directly from that disease or from an unrelated cause (for example, a car accident). When the precise cause of death is not specified, this is called the overall survival rate or observed survival rate. Doctors often use mean overall survival ...
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Bayesian Statistics
Bayesian statistics is a theory in the field of statistics based on the Bayesian interpretation of probability where probability expresses a ''degree of belief'' in an event. The degree of belief may be based on prior knowledge about the event, such as the results of previous experiments, or on personal beliefs about the event. This differs from a number of other interpretations of probability, such as the frequentist interpretation that views probability as the limit of the relative frequency of an event after many trials. Bayesian statistical methods use Bayes' theorem to compute and update probabilities after obtaining new data. Bayes' theorem describes the conditional probability of an event based on data as well as prior information or beliefs about the event or conditions related to the event. For example, in Bayesian inference, Bayes' theorem can be used to estimate the parameters of a probability distribution or statistical model. Since Bayesian statistics treats probabi ...
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