Barry James Thompson
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Barry James Thompson
Barry James Thompson (born 1978) is an Australian and British developmental biologist and cancer biologist. Thompson is known for identifying genes, proteins and mechanisms involved in epithelial polarity, morphogenesis and cell signaling via the Wnt and Hippo signaling pathways, which have key roles in human cancer. Early life and education Barry Thompson was born in 1978 into a British-Australian family. He was raised on the Atherton Tableland and in Brisbane in the state of Queensland (Australia). He attended Atherton State Primary School and Brisbane State High School and graduated as school Dux in 1995. Scientific career Thompson became interested in developmental biology and the control of tissue growth in 2000 when studying BSc(Hons) at the University of Queensland's Institute for Molecular Biology (IMB) with Professor Michael Waters. He earned his PhD degree at the MRC Laboratory of Molecular Biology and University of Cambridge (United Kingdom), where he stud ...
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Developmental Biology
Developmental biology is the study of the process by which animals and plants grow and develop. Developmental biology also encompasses the biology of Regeneration (biology), regeneration, asexual reproduction, metamorphosis, and the growth and differentiation of stem cells in the adult organism. Perspectives The main processes involved in the embryogenesis, embryonic development of animals are: tissue patterning (via regional specification and patterned cellular differentiation, cell differentiation); tissue growth; and tissue morphogenesis. * Regional specification refers to the processes that create the spatial patterns in a ball or sheet of initially similar cells. This generally involves the action of cytoplasmic determinants, located within parts of the fertilized egg, and of inductive signals emitted from signaling centers in the embryo. The early stages of regional specification do not generate functional differentiated cells, but cell populations committed to developing ...
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Wnt Signaling Pathway
The Wnt signaling pathways are a group of signal transduction pathways which begin with proteins that pass signals into a cell through cell surface receptors. The name Wnt is a portmanteau created from the names Wingless and Int-1. Wnt signaling pathways use either nearby cell-cell communication (paracrine) or same-cell communication (autocrine). They are highly evolutionarily conserved in animals, which means they are similar across animal species from fruit flies to humans. Three Wnt signaling pathways have been characterized: the canonical Wnt pathway, the noncanonical planar cell polarity pathway, and the noncanonical Wnt/calcium pathway. All three pathways are activated by the binding of a Wnt-protein ligand to a Frizzled family receptor, which passes the biological signal to the Dishevelled protein inside the cell. The canonical Wnt pathway leads to regulation of gene transcription, and is thought to be negatively regulated in part by the SPATS1 gene. The noncanonical plana ...
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Cell (journal)
''Cell'' is a peer-reviewed scientific journal publishing research papers across a broad range of disciplines within the life sciences. Areas covered include molecular biology, cell biology, systems biology, stem cells, developmental biology, genetics and genomics, proteomics, cancer research, immunology, neuroscience, structural biology, microbiology, virology, physiology, biophysics, and computational biology. The journal was established in 1974 by Benjamin LewinElsevier: ''Cell'': Home
(accessed 12 December 2008)
and is published twice monthly by , an imprint of

Current Biology
''Current Biology'' is a biweekly peer-reviewed scientific journal that covers all areas of biology, especially molecular biology, cell biology, genetics, neurobiology, ecology, and evolutionary biology. The journal includes research articles, various types of review articles, as well as an editorial magazine section. The journal was established in 1991 by the Current Science group, acquired by Elsevier in 1998 and has since 2001 been part of Cell Press, a subdivision of Elsevier. According to ''Journal Citation Reports'', the journal has a 2020 impact factor The impact factor (IF) or journal impact factor (JIF) of an academic journal is a scientometric index calculated by Clarivate that reflects the yearly mean number of citations of articles published in the last two years in a given journal, as i ... of 10.834. It was categorized as a "high impact journal" by the Superfund Research Program. References External links * Biology journals English-language journals Cell ...
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Nature Cell Biology
''Nature Cell Biology'' is a monthly peer review, peer-reviewed scientific journal published by Nature Portfolio. It was established in 1999. The founding editor was Annette Thomas. The current editor-in-chief is Christina Kary. According to the ''Journal Citation Reports'', the journal has a 2021 impact factor of 28.213. References External links

* Academic journals established in 1999 Nature Research academic journals Monthly journals Molecular and cellular biology journals {{molec-cell-biology-journal-stub ...
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Drosophila Melanogaster
''Drosophila melanogaster'' is a species of fly (the taxonomic order Diptera) in the family Drosophilidae. The species is often referred to as the fruit fly or lesser fruit fly, or less commonly the "vinegar fly" or "pomace fly". Starting with Charles W. Woodworth's 1901 proposal of the use of this species as a model organism, ''D. melanogaster'' continues to be widely used for biological research in genetics, physiology, microbial pathogenesis, and life history evolution. As of 2017, five Nobel Prizes have been awarded to drosophilists for their work using the insect. ''D. melanogaster'' is typically used in research owing to its rapid life cycle, relatively simple genetics with only four pairs of chromosomes, and large number of offspring per generation. It was originally an African species, with all non-African lineages having a common origin. Its geographic range includes all continents, including islands. ''D. melanogaster'' is a common pest in homes, restaurants, and othe ...
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Endocrinology
Endocrinology (from '' endocrine'' + '' -ology'') is a branch of biology and medicine dealing with the endocrine system, its diseases, and its specific secretions known as hormones. It is also concerned with the integration of developmental events proliferation, growth, and differentiation, and the psychological or behavioral activities of metabolism, growth and development, tissue function, sleep, digestion, respiration, excretion, mood, stress, lactation, movement, reproduction, and sensory perception caused by hormones. Specializations include behavioral endocrinology and comparative endocrinology. The endocrine system consists of several glands, all in different parts of the body, that secrete hormones directly into the blood rather than into a duct system. Therefore, endocrine glands are regarded as ductless glands. Hormones have many different functions and modes of action; one hormone may have several effects on different target organs, and, conversely, one target orga ...
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Growth Hormone
Growth hormone (GH) or somatotropin, also known as human growth hormone (hGH or HGH) in its human form, is a peptide hormone that stimulates growth, cell reproduction, and cell regeneration in humans and other animals. It is thus important in human development. GH also stimulates production of IGF-1 and increases the concentration of glucose and free fatty acids. It is a type of mitogen which is specific only to the receptors on certain types of cells. GH is a 191-amino acid, single-chain polypeptide that is synthesized, stored and secreted by somatotropic cells within the lateral wings of the anterior pituitary gland. A recombinant form of hGH called somatropin (INN) is used as a prescription drug to treat children's growth disorders and adult growth hormone deficiency. In the United States, it is only available legally from pharmacies by prescription from a licensed health care provider. In recent years in the United States, some health care providers are prescribing growth ...
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Developmental Biology
Developmental biology is the study of the process by which animals and plants grow and develop. Developmental biology also encompasses the biology of Regeneration (biology), regeneration, asexual reproduction, metamorphosis, and the growth and differentiation of stem cells in the adult organism. Perspectives The main processes involved in the embryogenesis, embryonic development of animals are: tissue patterning (via regional specification and patterned cellular differentiation, cell differentiation); tissue growth; and tissue morphogenesis. * Regional specification refers to the processes that create the spatial patterns in a ball or sheet of initially similar cells. This generally involves the action of cytoplasmic determinants, located within parts of the fertilized egg, and of inductive signals emitted from signaling centers in the embryo. The early stages of regional specification do not generate functional differentiated cells, but cell populations committed to developing ...
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Brisbane State High School
, motto_translation = Knowledge is Power , city = South Brisbane , state = Queensland , country = Australia , coordinates = , type = Public, selective, co-educational, secondary, day school , established = , principal = Wade Haynes , enrolment = 3,361 (7–12) (2020) , colours = Cerise and navy blue , website www.statehigh.com.au , campus = Urban (South Brisbane) Brisbane State High School (BSHS or often commonly State High) is a partially selective, co-educational, state secondary school, located in South Brisbane, Queensland, Australia. It is a member of the Great Public Schools Association of Queensland, and the Queensland Girls' Secondary Schools Sports Association. It was the first state secondary school established in Brisbane, as well as the first academic state high school to be founded in Queensland. The school employs a variety of selecti ...
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Atherton, Queensland
Atherton is a rural town and locality in the Tablelands Region, Queensland, Australia. In the , Atherton had a population of 7,331 people. Geography Atherton is on the Atherton Tableland in Far North Queensland. Atherton is joined by the Gillies Highway to Yungaburra, the Kennedy Highway north to Mareeba and south to Ravenshoe and Mount Garnet, the Malanda Road to Malanda and the Herberton Road to Herberton. History '' Yidinji'' (also known as ''Yidinj'', ''Yidiny'', and ''Idindji'') is an Australian Aboriginal language. Its traditional language region is within the local government areas of Cairns Region and Tablelands Region, in such localities as Cairns, Gordonvale, and the Mulgrave River, and the southern part of the Atherton Tableland including Atherton and Kairi. The town was named after John Atherton, a pioneer pastoralist who settled at Mareeba (then known as Emerald End) in 1875. The area was formerly known as Priors Pocket or Priors Creek. It was named ''Athe ...
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Queensland
) , nickname = Sunshine State , image_map = Queensland in Australia.svg , map_caption = Location of Queensland in Australia , subdivision_type = Country , subdivision_name = Australia , established_title = Before federation , established_date = Colony of Queensland , established_title2 = Separation from New South Wales , established_date2 = 6 June 1859 , established_title3 = Federation , established_date3 = 1 January 1901 , named_for = Queen Victoria , demonym = , capital = Brisbane , largest_city = capital , coordinates = , admin_center_type = Administration , admin_center = 77 local government areas , leader_title1 = Monarch , leader_name1 = Charles III , leader_title2 = Governor , leader_name2 = Jeannette Young , leader_title3 = Premier , leader_name3 = Annastacia Palaszczuk ( ALP) , legislature = Parliament of Queensland , judiciary = Supreme Court of Queensland , national_representation = Parliament of Australia , national_representation_type ...
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