Babylonia Japonica
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Babylonia Japonica
''Babylonia japonica'', common name the Japanese Babylon or Japanese ivory shell, is a species of sea snail, a marine gastropod mollusc in the family (biology), family Babyloniidae. Distribution This marine species occurs off Korea, Japan and Taiwan. Description The length of the shell varies between 40 mm and 85 mm. The ground color of the shell is white. The outer whorl has two rows of brown blotches among rows of fine spots. The pattern is similar to that of ''Babylonia zeylanica'' and ''Babylonia spirata, B. spirata'', but ''B. japonica'' has smaller and more numerous spots. In life, this shell is covered by a brown or tan periostracum. Human use Although this species is generally considered edible for humans, it is known to bioaccumulation, bioaccumulate toxins under certain conditions, namely the surugatoxin family, which causes ganglionic blocker, blockage of autonomic ganglia, and tetrodotoxin (pufferfish toxin). In September 1965 a food poisoning outbre ...
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Lovell Augustus Reeve
Lovell Augustus Reeve (19 April 1814 – 18 November 1865) was an English conchologist and publisher. Life Born at Ludgate Hill, London, on 19 April 1814, he was a son of Thomas Reeve, draper and mercer, by his wife Fanny Lovell. After attending school at Stockwell, he was apprenticed at the age of 13 to Mr. Graham, a local grocer. The chance of purchase of some shells led to a lifelong interest in conchology. In 1833 he attended the meeting of the British Association for the Advancement of Science at Cambridge. At the end of his apprenticeship Reeve paid a visit to Paris, where he read a paper on the classification of Mollusca before the Academy of Sciences. On his return to London, he set to work on his first book, ''Conchologia Systematica'' (2 vols. London, 1841–2). From 1842, he traded as a natural history dealer. Using profits made by the sale of Dutch Governor-General of the Moluccas Van Ryder's collection from the Moluccas, which he purchased at Rotterdam, and with t ...
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Periostracum
The periostracum ( ) is a thin, organic coating (or "skin") that is the outermost layer of the shell of many shelled animals, including molluscs and brachiopods. Among molluscs, it is primarily seen in snails and clams, i.e. in gastropods and bivalves, but it is also found in cephalopods such as ''Allonautilus scrobiculatus''. The periostracum is an integral part of the shell, and it forms as the shell forms, along with the other shell layers. The periostracum is used to protect the organism from corrosion. The periostracum is visible as the outer layer of the shell of many molluscan species from terrestrial, freshwater, and marine habitats, and may be seen in land snails, river mussels, and other kinds of freshwater bivalves, as well as in many kinds of marine shelled molluscs. The word ''periostracum'' means "around the shell", meaning that the periostracum is wrapped around what is usually the more calcareous part of the shell. Technically, the calcareous part of the shel ...
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Sympathetic Nervous System
The sympathetic nervous system (SNS) is one of the three divisions of the autonomic nervous system, the others being the parasympathetic nervous system and the enteric nervous system. The enteric nervous system is sometimes considered part of the autonomic nervous system, and sometimes considered an independent system. The autonomic nervous system functions to regulate the body's unconscious actions. The sympathetic nervous system's primary process is to stimulate the body's fight or flight response. It is, however, constantly active at a basic level to maintain homeostasis. The sympathetic nervous system is described as being antagonistic to the parasympathetic nervous system which stimulates the body to "feed and breed" and to (then) "rest-and-digest". Structure There are two kinds of neurons involved in the transmission of any signal through the sympathetic system: pre-ganglionic and post-ganglionic. The shorter preganglionic neurons originate in the thoracolumbar division o ...
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Parasympathetic Nervous System
The parasympathetic nervous system (PSNS) is one of the three divisions of the autonomic nervous system, the others being the sympathetic nervous system and the enteric nervous system. The enteric nervous system is sometimes considered part of the autonomic nervous system, and sometimes considered an independent system. The autonomic nervous system is responsible for regulating the body's unconscious actions. The parasympathetic system is responsible for stimulation of "rest-and-digest" or "feed and breed" activities that occur when the body is at rest, especially after eating, including sexual arousal, salivation, lacrimation (tears), urination, digestion, and defecation. Its action is described as being complementary to that of the sympathetic nervous system, which is responsible for stimulating activities associated with the fight-or-flight response. Nerve fibres of the parasympathetic nervous system arise from the central nervous system. Specific nerves include several ...
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Suruga Bay
Suruga Bay (駿河湾, ''Suruga-wan'') is a bay on the Pacific coast of Honshū in Shizuoka Prefecture, Japan. It is situated north of a straight line from Omaezaki Point to Irōzaki Point at the tip of the Izu Peninsula and surrounded by Honshū to the southwest and west and the Izu Peninsula to the east. Geology Suruga Bay is a place of contrasts. Japan's loftiest peak, Mount Fuji at , rises from the depth of the Suruga Trough running up the middle of the bay, which makes it Japan's deepest. Numerous rivers—especially the major Fuji, the Ōi, and Abe rivers—empty into its western portion, giving that area of the bay a seabed rich in submarine canyons and other geographical features, whereas at the bay's easternmost end, only the Kano River empties into a pocket called Uchiura-wan at Numazu, Shizuoka, where the Izu Peninsula connects to Honshu, giving the water greater transparency and leaving the seabed largely flat except for a number of small rocky islands, some joined ...
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Food Poisoning
Foodborne illness (also foodborne disease and food poisoning) is any illness resulting from the spoilage of contaminated food by pathogenic bacteria, viruses, or parasites that contaminate food, as well as prions (the agents of mad cow disease), and toxins such as aflatoxins in peanuts, poisonous mushrooms, and various species of beans that have not been boiled for at least 10 minutes. Symptoms vary depending on the cause but often include vomiting, fever, and aches, and may include diarrhea. Bouts of vomiting can be repeated with an extended delay in between, because even if infected food was eliminated from the stomach in the first bout, microbes, like bacteria (if applicable), can pass through the stomach into the intestine and begin to multiply. Some types of microbes stay in the intestine. For contaminants requiring an incubation period, symptoms may not manifest for hours to days, depending on the cause and on quantity of consumption. Longer incubation periods tend to cau ...
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Tetrodotoxin
Tetrodotoxin (TTX) is a potent neurotoxin. Its name derives from Tetraodontiformes, an order that includes pufferfish, porcupinefish, ocean sunfish, and triggerfish; several of these species carry the toxin. Although tetrodotoxin was discovered in these fish and found in several other animals (e.g., in blue-ringed octopuses, rough-skinned newts, and moon snails), it is actually produced by certain infecting or symbiotic bacteria like ''Pseudoalteromonas'', ''Pseudomonas'', and ''Vibrio'' as well as other species found in animals. Tetrodotoxin is a sodium channel blocker. It inhibits the firing of action potentials in neurons by binding to the voltage-gated sodium channels in nerve cell membranes and blocking the passage of sodium ions (responsible for the rising phase of an action potential) into the neuron. This prevents the nervous system from carrying messages and thus muscles from contracting in response to nervous stimulation. Its mechanism of action, selective blocking o ...
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Autonomic Ganglia
An autonomic ganglion is a cluster of nerve cell bodies (a ganglion) in the autonomic nervous system The autonomic nervous system (ANS), formerly referred to as the vegetative nervous system, is a division of the peripheral nervous system that supplies viscera, internal organs, smooth muscle and glands. The autonomic nervous system is a control .... The two types are the sympathetic ganglion and the parasympathetic ganglion. References {{Authority control Autonomic nervous system ...
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Ganglionic Blocker
A ganglionic blocker (or ganglioplegic) is a type of medication that inhibits transmission between preganglionic and postganglionic neurons in the autonomic nervous system, often by acting as a nicotinic receptor antagonist. Nicotinic acetylcholine receptors are found on skeletal muscle, but also within the route of transmission for the parasympathetic and sympathetic nervous system (which together comprise the autonomic nervous system). More specifically, nicotinic receptors are found within the ganglia of the autonomic nervous system, allowing outgoing signals to be transmitted from the presynaptic to the postsynaptic cells. Thus, for example, blocking nicotinic acetylcholine receptors blocks both sympathetic (excitatory) and parasympathetic (calming) stimulation of the heart. The nicotinic antagonist hexamethonium, for example, does this by blocking the transmission of outgoing signals across the autonomic ganglia at the postsynaptic nicotinic acetylcholine receptor. Because ga ...
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Surugatoxin
Surugatoxin (SGTX) is a type of venom found in the mid-gut digestive gland of the Japanese ivory mollusk ''Babylonia'' ''japonica'', a carnivorous gastropod. It functions as a ganglionic blocker of nicotinic acetylcholine receptors (nAChRs). The structurally and functionally related neosurugatoxin, also derived from ''Babylonia japonica'', is an even more potent nAChR antagonist than SGTX. SGTX is a colorless crystalline substance with the chemical formula C25H26BrN5O13 and a molecular weight of 684.4g/mol. Its systematic chemical name is 2R,3S,5S,6S)-2,3,4,5,6-pentahydroxycyclohexyl(6aS,7R,8R,9R)-6'-bromo-6a,9-dihydroxy-9-methyl-1,2',3,10-tetraoxo-spiro ,5,6,7-tetrahydropyrido[1,2-fteridine-8,3'-indoline">,2-f.html" ;"title=",5,6,7-tetrahydropyrido[1,2-f">,5,6,7-tetrahydropyrido[1,2-fteridine-8,3'-indoline7-carboxylate. It is insoluble in organic solvents and has very low solubility in water. The ganglionic blockade of nAChRs by SGTX is similar to that of IS-toxin, a struc ...
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Bioaccumulation
Bioaccumulation is the gradual accumulation of substances, such as pesticides or other chemicals, in an organism. Bioaccumulation occurs when an organism absorbs a substance at a rate faster than that at which the substance is lost or eliminated by catabolism and excretion. Thus, the longer the biological half-life of a toxic substance, the greater the risk of chronic poisoning, even if environmental levels of the toxin are not very high. Bioaccumulation, for example in fish, can be predicted by models. Hypothesis for molecular size cutoff criteria for use as bioaccumulation potential indicators are not supported by data. Biotransformation can strongly modify bioaccumulation of chemicals in an organism. Toxicity induced by metals is associated with bioaccumulation and biomagnification. Storage or uptake of metals faster than the rate at which an organism metabolizes and excretes lead to the accumulation of that metal. The presence of various chemicals and harmful substances in ...
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Babylonia Japonica 03 At A Fishmarket
Babylonia (; Akkadian: , ''māt Akkadī'') was an ancient Akkadian-speaking state and cultural area based in the city of Babylon in central-southern Mesopotamia (present-day Iraq and parts of Syria). It emerged as an Amorite-ruled state c. 1894 BCE. During the reign of Hammurabi and afterwards, Babylonia was called "the country of Akkad" (''Māt Akkadī'' in Akkadian), a deliberate archaism in reference to the previous glory of the Akkadian Empire. It was often involved in rivalry with the older state of Assyria to the north and Elam to the east in Ancient Iran. Babylonia briefly became the major power in the region after Hammurabi (fl. c. 1792–1752 BCE middle chronology, or c. 1696–1654 BCE, short chronology) created a short-lived empire, succeeding the earlier Akkadian Empire, Third Dynasty of Ur, and Old Assyrian Empire. The Babylonian Empire rapidly fell apart after the death of Hammurabi and reverted to a small kingdom. Like Assyria, the Babylonian state r ...
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