Autologous Conditioned Serum
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Autologous Conditioned Serum
Autologous conditioned serum, also known as Orthokine and Regenokine, is an experimental procedure in which a person's own blood is extracted, manipulated, and then reintroduced with claimed benefit in osteoarthritis. There is limited evidence on safety and effectiveness as of 2017. It is not included in medical guidelines as of 2017. It is a type of autologous blood therapy. Medical use There is limited evidence on safety and effectiveness as of 2017. There is tentative evidence in osteoarthritis. Its use has not been recommended or considered by the Osteoarthritis Research Society International. Process The process removes about of blood from a patient's arm, which is then incubated at a slightly raised temperature. The liquid is then placed in a centrifuge until its constituent parts are separated. That serum is injected into the patient's affected area. History Autologous conditioned serum is a patented method developed by molecular biologist Julio Reinecke and Peter Wehl ...
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Osteoarthritis
Osteoarthritis (OA) is a type of degenerative joint disease that results from breakdown of joint cartilage and underlying bone which affects 1 in 7 adults in the United States. It is believed to be the fourth leading cause of disability in the world. The most common symptoms are joint pain and stiffness. Usually the symptoms progress slowly over years. Initially they may occur only after exercise but can become constant over time. Other symptoms may include joint swelling, decreased range of motion, and, when the back is affected, weakness or numbness of the arms and legs. The most commonly involved joints are the two near the ends of the fingers and the joint at the base of the thumbs; the knee and hip joints; and the joints of the neck and lower back. Joints on one side of the body are often more affected than those on the other. The symptoms can interfere with work and normal daily activities. Unlike some other types of arthritis, only the joints, not internal organs, are af ...
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Platelet-rich Plasma
Platelet-rich plasma (PRP), also known as autologous conditioned plasma, is a concentrate of platelet-rich plasma protein derived from whole blood, centrifuged to remove red blood cells. Though promoted to treat an array of medical problems, evidence for benefit is mixed as of 2020, with some evidence for use in certain conditions and against use in other conditions. As a concentrated source of blood plasma and autologous conditioned plasma, PRP contains several different growth factors and other cytokines that can stimulate healing of soft tissue and joints. There are some indications for use in sports medicine and orthopedics (acute muscle strains, tendinopathy and muscle-fascial injuries and osteoarthritis), or dermatology (androgenic alopecia, wound healing, and skin rejuvenation) or even in proctology (fistula-in-ano). For preparation of PRP, various protocols are used, with an underlying principle of concentrating platelets to 3–5 times physiological levels, then injectin ...
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Biotechnology Products
Biotechnology is the integration of natural sciences and engineering sciences in order to achieve the application of organisms, cells, parts thereof and molecular analogues for products and services. The term ''biotechnology'' was first used by Károly Ereky in 1919, meaning the production of products from raw materials with the aid of living organisms. Definition The concept of biotechnology encompasses a wide range of procedures for modifying living organisms according to human purposes, going back to domestication of animals, cultivation of the plants, and "improvements" to these through breeding programs that employ artificial selection and hybridization. Modern usage also includes genetic engineering as well as cell and tissue culture technologies. The American Chemical Society defines biotechnology as the application of biological organisms, systems, or processes by various industries to learning about the science of life and the improvement of the value of materials ...
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Health Insurance
Health insurance or medical insurance (also known as medical aid in South Africa) is a type of insurance that covers the whole or a part of the risk of a person incurring medical expenses. As with other types of insurance, risk is shared among many individuals. By estimating the overall risk of health risk and health system expenses over the risk pool, an insurer can develop a routine finance structure, such as a monthly premium or payroll tax, to provide the money to pay for the health care benefits specified in the insurance agreement. The benefit is administered by a central organization, such as a government agency, private business, or not-for-profit entity. According to the Health Insurance Association of America, health insurance is defined as "coverage that provides for the payments of benefits as a result of sickness or injury. It includes insurance for losses from accident, medical expense, disability, or accidental death and dismemberment". Background A health i ...
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Kobe Bryant
Kobe Bean Bryant ( ; August 23, 1978 – January 26, 2020) was an American professional basketball player. A shooting guard, he spent his entire 20-year career with the Los Angeles Lakers in the National Basketball Association (NBA). Widely regarded as one of the greatest basketball players and scorers of all time, Bryant won five NBA championships, was an 18-time All-Star, a 15-time member of the All-NBA Team, a 12-time member of the All-Defensive Team, the 2008 NBA Most Valuable Player (MVP), and a two-time NBA Finals MVP. Bryant also led the NBA in scoring twice, and ranks fourth in league all-time regular season and postseason scoring. He was posthumously voted into the Naismith Memorial Basketball Hall of Fame in 2020 and named to the NBA 75th Anniversary Team in 2021. The son of former NBA player Joe Bryant, he was born in Philadelphia and partly raised in Italy. Recognized as the top American high-school basketball player while at Philadelphia suburb Lower Merion ...
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National Basketball Association
The National Basketball Association (NBA) is a professional basketball league in North America. The league is composed of 30 teams (29 in the United States and 1 in Canada) and is one of the major professional sports leagues in the United States and Canada. It is the premier men's professional basketball league in the world. The league was founded in New York City on June 6, 1946, as the Basketball Association of America (BAA). It changed its name to the National Basketball Association on August 3, 1949, after merging with the competing National Basketball League (NBL). In 1976, the NBA and the American Basketball Association (ABA) merged, adding four franchises to the NBA. The NBA's regular season runs from October to April, with each team playing 82 games. The league's playoff tournament extends into June. , NBA players are the world's best paid athletes by average annual salary per player. The NBA is an active member of USA Basketball (USAB), which is recognized by t ...
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University Of Pittsburgh
The University of Pittsburgh (Pitt) is a public state-related research university in Pittsburgh, Pennsylvania. The university is composed of 17 undergraduate and graduate schools and colleges at its urban Pittsburgh campus, home to the university's central administration and around 28,000 undergraduate and graduate students. The 132-acre Pittsburgh campus includes various historic buildings that are part of the Schenley Farms Historic District, most notably its 42-story Gothic revival centerpiece, the Cathedral of Learning. Pitt is a member of the Association of American Universities and is classified among "R1: Doctoral Universities – Very high research activity". It is the second-largest non-government employer in the Pittsburgh metropolitan area. Pitt traces its roots to the Pittsburgh Academy founded by Hugh Henry Brackenridge in 1787. While the city was still on the edge of the American frontier at the time, Pittsburgh's rapid growth meant that a proper university was so ...
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Freddie Fu
Freddie H. Fu ( zh, t=傅浩強, j=Fu6 Hou6-koeng4; (1950 – September 24, 2021) was a Hong Kongese-American doctor and academic. He was the David Silver Professor and chairman of the Department of Orthopaedic Surgery at the University of Pittsburgh School of Medicine. In 2010, he was appointed by the University of Pittsburgh as the eighth distinguished service professor. He died due to metastatic melanoma on 24 September 2021. Career Fu was born in Hong Kong, his ancestral hometown is Nanhai district, Foshan city, Guangdong province. He attended Dartmouth College, where he was a member of the Alpha Chi Alpha fraternity. Dr. Fu was president of the Pennsylvania Orthopaedic Society and, in 2008, assumed the presidency of the American Orthopaedic Society for Sports Medicine (AOSSM) and was the first foreign-born president in AOSSM's 40-year history. In 2009, he was named president of the International Society of Arthroscopy, Knee Surgery and Orthopaedic Sports Medicine. In 2011, ...
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Platelets
Platelets, also called thrombocytes (from Greek θρόμβος, "clot" and κύτος, "cell"), are a component of blood whose function (along with the coagulation factors) is to react to bleeding from blood vessel injury by clumping, thereby initiating a blood clot. Platelets have no cell nucleus; they are fragments of cytoplasm that are derived from the megakaryocytes of the bone marrow or lung, which then enter the circulation. Platelets are found only in mammals, whereas in other vertebrates (e.g. birds, amphibians), thrombocytes circulate as intact mononuclear cells. One major function of platelets is to contribute to hemostasis: the process of stopping bleeding at the site of interrupted endothelium. They gather at the site and, unless the interruption is physically too large, they plug the hole. First, platelets attach to substances outside the interrupted endothelium: ''adhesion''. Second, they change shape, turn on receptors and secrete chemical messengers: ''activatio ...
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Düsseldorf
Düsseldorf ( , , ; often in English sources; Low Franconian and Ripuarian: ''Düsseldörp'' ; archaic nl, Dusseldorp ) is the capital city of North Rhine-Westphalia, the most populous state of Germany. It is the second-largest city in the state and the seventh-largest city in Germany, with a population of 617,280. Düsseldorf is located at the confluence of two rivers: the Rhine and the Düssel, a small tributary. The ''-dorf'' suffix means "village" in German (English cognate: ''thorp''); its use is unusual for a settlement as large as Düsseldorf. Most of the city lies on the right bank of the Rhine. Düsseldorf lies in the centre of both the Rhine-Ruhr and the Rhineland Metropolitan Region. It neighbours the Cologne Bonn Region to the south and the Ruhr to the north. It is the largest city in the German Low Franconian dialect area (closely related to Dutch). Mercer's 2012 Quality of Living survey ranked Düsseldorf the sixth most livable city in the world. Düsse ...
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Medical Guidelines
Medicine is the science and practice of caring for a patient, managing the diagnosis, prognosis, prevention, treatment, palliation of their injury or disease, and promoting their health. Medicine encompasses a variety of health care practices evolved to maintain and restore health by the prevention and treatment of illness. Contemporary medicine applies biomedical sciences, biomedical research, genetics, and medical technology to diagnose, treat, and prevent injury and disease, typically through pharmaceuticals or surgery, but also through therapies as diverse as psychotherapy, external splints and traction, medical devices, biologics, and ionizing radiation, amongst others. Medicine has been practiced since prehistoric times, and for most of this time it was an art (an area of skill and knowledge), frequently having connections to the religious and philosophical beliefs of local culture. For example, a medicine man would apply herbs and say prayers for healing, or an ancie ...
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Spinal Surgeon
Neurosurgery or neurological surgery, known in common parlance as brain surgery, is the medical specialty concerned with the surgical treatment of disorders which affect any portion of the nervous system including the brain, spinal cord and peripheral nervous system. Education and context In different countries, there are different requirements for an individual to legally practice neurosurgery, and there are varying methods through which they must be educated. In most countries, neurosurgeon training requires a minimum period of seven years after graduating from medical school. United States In the United States, a neurosurgeon must generally complete four years of undergraduate education, four years of medical school, and seven years of residency (PGY-1-7). Most, but not all, residency programs have some component of basic science or clinical research. Neurosurgeons may pursue additional training in the form of a fellowship after residency, or, in some cases, as a senior resid ...
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