Australian Regenerative Medicine Institute
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Australian Regenerative Medicine Institute
The Australian Regenerative Medicine Institute (ARMI) is an Australian medical research institute. Opened in April 2009, the institute is based at the campus of Monash University, in the Monash Science Technology Research and Innovation Precinct. ARMI is one of the world's largest regenerative medicine and stem cell research hubs. Its research aims to restore and regenerate damaged tissue and organs by injecting or implanting cells to allow the human body to heal and recover. Research focuses on developing effective treatments for a range of currently incurable diseases, such as cancer, arthritis and other musculoskeletal conditions, diabetes and cardiovascular diseases, as well as neurotrauma. In addition, ARMI is also looking at technologies to treat ageing itself via regeneration. Facilities at the Institute include FishCore, the largest zebrafish facility of its kind in the Southern Hemisphere. Leadership The institute was established through an 153 million joint ventu ...
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Nadia Rosenthal
Nadia A. Rosenthal FMedSci is a scientist who specializes in heart development related research. Rosenthal began her undergraduate degree at the University of Wales and then transferred to Harvard. She received her PhD from Harvard Medical School and was an associate professor of biochemistry at Boston University and an associate professor of medicine at Harvard Medical School before transferring to the European Molecular Biology Laboratory where she replaced Klaus Rajewsky who had just gone to work at Harvard Medical School. In 2006, she presented the Howard Hughes Medical Institute's Holiday Lectures together with Douglas A. Melton. She is the editor-in-chief of '' Differentiation''. Since 2005 Rosenthal has been chair in Cardiovascular Science at Imperial College London. In 2008, Rosenthal was appointed as founding director of the Australian Regenerative Medicine Institute, based at Monash University in Melbourne. Since 2014, she has served as scientific director of the Jackso ...
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Stem Cell
In multicellular organisms, stem cells are undifferentiated or partially differentiated cells that can differentiate into various types of cells and proliferate indefinitely to produce more of the same stem cell. They are the earliest type of cell in a cell lineage. They are found in both embryonic and adult organisms, but they have slightly different properties in each. They are usually distinguished from progenitor cells, which cannot divide indefinitely, and precursor or blast cells, which are usually committed to differentiating into one cell type. In mammals, roughly 50–150 cells make up the inner cell mass during the blastocyst stage of embryonic development, around days 5–14. These have stem-cell capability. ''In vivo'', they eventually differentiate into all of the body's cell types (making them pluripotent). This process starts with the differentiation into the three germ layers – the ectoderm, mesoderm and endoderm – at the gastrulation stage. However ...
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Medical Research Institutes In Melbourne
Medicine is the science and practice of caring for a patient, managing the diagnosis, prognosis, prevention, treatment, palliation of their injury or disease, and promoting their health. Medicine encompasses a variety of health care practices evolved to maintain and restore health by the prevention and treatment of illness. Contemporary medicine applies biomedical sciences, biomedical research, genetics, and medical technology to diagnose, treat, and prevent injury and disease, typically through pharmaceuticals or surgery, but also through therapies as diverse as psychotherapy, external splints and traction, medical devices, biologics, and ionizing radiation, amongst others. Medicine has been practiced since prehistoric times, and for most of this time it was an art (an area of skill and knowledge), frequently having connections to the religious and philosophical beliefs of local culture. For example, a medicine man would apply herbs and say prayers for healing, ...
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Health In Australia
Australia is a high income country, and this is reflected in the good status of health of the population overall. In 2011, Australia ranked 2nd on the United Nations Development Programme’s Human Development Index, indicating the level of development of a country. Despite the overall good status of health, the disparities occurring in the Australian healthcare system are a problem. The poor and those living in remote areas as well as indigenous people are, in general, less healthy than others in the population, and programs have been implemented to decrease this gap. These include increased outreach to the indigenous communities and government subsidies to provide services for people in remote or rural areas. Life expectancy Life expectancy in Australia is among the highest in the world. According to the 2013 Global Burden of Disease Study Australia was ranked third highest in life expectancy. The life expectancy (at birth) in 2015 was estimated to be 79.7 years for males and ...
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Australian Stem Cell Centre
The Australian Stem Cell Centre is an Australian medical research and development centre which focuses on regenerative medicine through the use of stem cells. Founded in 2003, the Centre is the National Biotechnology Centre of Excellence and has received over $100 million in funding in recent years. It is Australia's premier stem cell research organisation. In June 2008, the Centre announced that it had begun working on induced pluripotent (iPS) cells (human embryonic stem cells, artificially created without human eggs or embryos). This was the first time in Australia that such research had been carried out, and the first time that scientists had worked on this type of stem cell outside the US or Japan. It is based at Monash Science Technology Research and Innovation Precinct and was founded by nine leading Australian universities and medical research institutes. One of the founders of the Centre is Dr Alan Trounson, a Monash scientist who was part of the team that delivered A ...
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Harvard Medical School
Harvard Medical School (HMS) is the graduate medical school of Harvard University and is located in the Longwood Medical Area of Boston, Massachusetts. Founded in 1782, HMS is one of the oldest medical schools in the United States and is consistently ranked first for research among medical schools by '' U.S. News & World Report''. Unlike most other leading medical schools, HMS does not operate in conjunction with a single hospital but is directly affiliated with several teaching hospitals in the Boston area. Affiliated teaching hospitals and research institutes include Dana–Farber Cancer Institute, Massachusetts General Hospital, Brigham and Women's Hospital, Beth Israel Deaconess Medical Center, Boston Children's Hospital, McLean Hospital, Cambridge Health Alliance, The Baker Center for Children and Families, and Spaulding Rehabilitation Hospital. History Harvard Medical School was founded on September 19, 1782, after President Joseph Willard presented a report with ...
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European Molecular Biology Laboratory
The European Molecular Biology Laboratory (EMBL) is an intergovernmental organization dedicated to molecular biology research and is supported by 27 member states, two prospect states, and one associate member state. EMBL was created in 1974 and is funded by public research money from its member states. Research at EMBL is conducted by approximately 110 independent research and service groups and teams covering the spectrum of molecular biology and bioinformatics. The list of Groups and Teams at EMBL can be found at . The Laboratory operates from six sites: the main laboratory in Heidelberg, and sites in Hinxton (the European Bioinformatics Institute (EBI), in England), Grenoble (France), Hamburg (Germany), Rome (Italy) and Barcelona (Spain). EMBL groups and laboratories perform basic research in molecular biology and molecular medicine as well as train scientists, students, and visitors. The organization aids in the development of services, new instruments and methods, and techn ...
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Zebrafish
The zebrafish (''Danio rerio'') is a freshwater fish belonging to the minnow family ( Cyprinidae) of the order Cypriniformes. Native to South Asia, it is a popular aquarium fish, frequently sold under the trade name zebra danio (and thus often called a "tropical fish" although both tropical and subtropical). It is also found in private ponds. The zebrafish is an important and widely used vertebrate model organism in scientific research, for example in drug development, in particular pre-clinical development. It is also notable for its regenerative abilities, and has been modified by researchers to produce many transgenic strains. Taxonomy The zebrafish is a derived member of the genus '' Brachydanio'', of the family Cyprinidae. It has a sister-group relationship with ''Danio aesculapii''. Zebrafish are also closely related to the genus ''Devario'', as demonstrated by a phylogenetic tree of close species. Distribution Range The zebrafish is native to fresh water h ...
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Government Of Victoria
The Victoria State Government, also referred to as just the Victorian Government, is the state-level authority for Victoria (Australia), Victoria, Australia. Like all state governments, it is formed by three independent branches: the executive, the Supreme Court of Victoria, judicial, and the Parliament of Victoria, parliament. As a parliamentary system, parliamentary constitutional monarchy, the State Government was first formed in 1851 when Victoria first gained the right to responsible government. The Constitution of Australia regulates the relationship between the Victorian Government and the Australian Government, and cedes legislative and judicial supremacy to the federal government on conflicting matters. The Victoria State Government enforces Act of Parliament, acts passed by the parliament through government departments, statutory authorities, and other public agencies. The Government is formally presided over by the Governor of Victoria, Governor, who exercises execu ...
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Regenerative Medicine
Regenerative medicine deals with the "process of replacing, engineering or regenerating human or animal cells, tissues or organs to restore or establish normal function". This field holds the promise of engineering damaged tissues and organs by stimulating the body's own repair mechanisms to functionally heal previously irreparable tissues or organs. Regenerative medicine also includes the possibility of growing tissues and organs in the laboratory and implanting them when the body cannot heal itself. When the cell source for a regenerated organ is derived from the patient's own tissue or cells, the challenge of organ transplant rejection via immunological mismatch is circumvented. This approach could alleviate the problem of the shortage of organs available for donation. Some of the biomedical approaches within the field of regenerative medicine may involve the use of stem cells. Examples include the injection of stem cells or progenitor cells obtained through directed differenti ...
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Medical Research
Medical research (or biomedical research), also known as experimental medicine, encompasses a wide array of research, extending from "basic research" (also called ''bench science'' or ''bench research''), – involving fundamental scientific principles that may apply to a ''preclinical'' understanding – to clinical research, which involves studies of people who may be subjects in clinical trials. Within this spectrum is applied research, or translational research, conducted to expand knowledge in the field of medicine. Both clinical and preclinical research phases exist in the pharmaceutical industry's drug development pipelines, where the clinical phase is denoted by the term ''clinical trial''. However, only part of the clinical or preclinical research is oriented towards a specific pharmaceutical purpose. The need for fundamental and mechanism-based understanding, diagnostics, medical devices, and non-pharmaceutical therapies means that pharmaceutical research i ...
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