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Austin Bradford Hill
Sir Austin Bradford Hill (8 July 1897 – 18 April 1991) was an English epidemiologist and statistician, pioneered the randomised clinical trial and, together with Richard Doll, demonstrated the connection between cigarette smoking and lung cancer. Hill is widely known for pioneering the "Bradford Hill" criteria for determining a causal association. Early life Hill was born in London, son of Sir Leonard Erskine Hill FRS, a distinguished physiologist, and Janet Alexander. He was the grandson of noted scholar George Birkbeck Hill. As a child he lived at the family home, Osborne House, Loughton, Essex; he was educated at Chigwell School, Essex. He served as a pilot in the First World War but was invalided out when he contracted tuberculosis. Two years in hospital and two years of convalescence put a medical qualification out of the question and he took a degree in economics by correspondence at London University. Career In 1922, Hill went to work for the Industry Fatigue Resea ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Hampstead
Hampstead () is an area in London, which lies northwest of Charing Cross, and extends from Watling Street, the A5 road (Roman Watling Street) to Hampstead Heath, a large, hilly expanse of parkland. The area forms the northwest part of the London Borough of Camden, a borough in Inner London which for the purposes of the London Plan is designated as part of Central London. Hampstead is known for its intellectual, liberal, artistic, musical, and literary associations. It has some of the most expensive housing in the London area. Hampstead has more millionaires within its boundaries than any other area of the United Kingdom.Wade, David"Whatever happened to Hampstead Man?" ''The Daily Telegraph'', 8 May 2004 (retrieved 3 March 2016). History Toponymy The name comes from the Old English, Anglo-Saxon words ''ham'' and ''stede'', which means, and is a cognate of, the Modern English "homestead". To 1900 Early records of Hampstead can be found in a grant by King Ethelred the Unread ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Karl Pearson
Karl Pearson (; born Carl Pearson; 27 March 1857 – 27 April 1936) was an English mathematician and biostatistician. He has been credited with establishing the discipline of mathematical statistics. He founded the world's first university statistics department at University College, London in 1911, and contributed significantly to the field of biometrics and meteorology. Pearson was also a proponent of social Darwinism, eugenics and scientific racism. Pearson was a protégé and biographer of Sir Francis Galton. He edited and completed both William Kingdon Clifford's ''Common Sense of the Exact Sciences'' (1885) and Isaac Todhunter's ''History of the Theory of Elasticity'', Vol. 1 (1886–1893) and Vol. 2 (1893), following their deaths. Biography Pearson was born in Islington, London into a Quaker family. His father was William Pearson QC of the Inner Temple, and his mother Fanny (née Smith), and he had two siblings, Arthur and Amy. Pearson attended University College Scho ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Poliomyelitis
Poliomyelitis, commonly shortened to polio, is an infectious disease caused by the poliovirus. Approximately 70% of cases are asymptomatic; mild symptoms which can occur include sore throat and fever; in a proportion of cases more severe symptoms develop such as headache, neck stiffness, and paresthesia. These symptoms usually pass within one or two weeks. A less common symptom is permanent paralysis, and possible death in extreme cases.. Years after recovery, post-polio syndrome may occur, with a slow development of muscle weakness similar to that which the person had during the initial infection. Polio occurs naturally only in humans. It is highly infectious, and is spread from person to person either through fecal-oral transmission (e.g. poor hygiene, or by ingestion of food or water contaminated by human feces), or via the oral-oral route. Those who are infected may spread the disease for up to six weeks even if no symptoms are present. The disease may be diagnosed by ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Royal Society
The Royal Society, formally The Royal Society of London for Improving Natural Knowledge, is a learned society and the United Kingdom's national academy of sciences. The society fulfils a number of roles: promoting science and its benefits, recognising excellence in science, supporting outstanding science, providing scientific advice for policy, education and public engagement and fostering international and global co-operation. Founded on 28 November 1660, it was granted a royal charter by King Charles II as The Royal Society and is the oldest continuously existing scientific academy in the world. The society is governed by its Council, which is chaired by the Society's President, according to a set of statutes and standing orders. The members of Council and the President are elected from and by its Fellows, the basic members of the society, who are themselves elected by existing Fellows. , there are about 1,700 fellows, allowed to use the postnominal title FRS (Fellow of the ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Royal Statistical Society
The Royal Statistical Society (RSS) is an established statistical society. It has three main roles: a British learned society for statistics, a professional body for statisticians and a charity which promotes statistics for the public good. History The society was founded in 1834 as the Statistical Society of London, though a perhaps unrelated London Statistical Society was in existence at least as early as 1824. At that time there were many provincial statistics societies throughout Britain, but most have not survived. The Manchester Statistical Society (which is older than the LSS) is a notable exception. The associations were formed with the object of gathering information about society. The idea of statistics referred more to political knowledge rather than a series of methods. The members called themselves "statists" and the original aim was "...procuring, arranging and publishing facts to illustrate the condition and prospects of society" and the idea of interpretin ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Epidemiology
Epidemiology is the study and analysis of the distribution (who, when, and where), patterns and determinants of health and disease conditions in a defined population. It is a cornerstone of public health, and shapes policy decisions and evidence-based practice by identifying risk factors for disease and targets for preventive healthcare. Epidemiologists help with study design, collection, and statistical analysis of data, amend interpretation and dissemination of results (including peer review and occasional systematic review). Epidemiology has helped develop methodology used in clinical research, public health studies, and, to a lesser extent, basic research in the biological sciences. Major areas of epidemiological study include disease causation, transmission, outbreak investigation, disease surveillance, environmental epidemiology, forensic epidemiology, occupational epidemiology, screening, biomonitoring, and comparisons of treatment effects such as in clinical trials. ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Peter Armitage (statistician)
Peter Armitage CBE (born 15 June 1924) is a statistician specialising in medical statistics. Peter Armitage attended Huddersfield College and went on to read mathematics at Trinity College, Cambridge. Armitage belonged to the generation of mathematicians who came to maturity in the Second World War. He joined the weapons procurement agency, the Ministry of Supply where he worked on statistical problems with George Barnard. After the war he resumed his studies and then worked as a statistician for the Medical Research Council from 1947 to 1961. From 1961 to 1976, he was Professor of Medical Statistics at the London School of Hygiene and Tropical Medicine where he succeeded Austin Bradford Hill. His main work there was on sequential analysis. He moved to Oxford as Professor of Biomathematics and became Professor of Applied Statistics and head of the new Department of Statistics, retiring in 1990. He was president of the Royal Statistical Society in 1982–4. He was president of ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Causality
Causality (also referred to as causation, or cause and effect) is influence by which one event, process, state, or object (''a'' ''cause'') contributes to the production of another event, process, state, or object (an ''effect'') where the cause is partly responsible for the effect, and the effect is partly dependent on the cause. In general, a process has many causes, which are also said to be ''causal factors'' for it, and all lie in its past. An effect can in turn be a cause of, or causal factor for, many other effects, which all lie in its future. Some writers have held that causality is metaphysically prior to notions of time and space. Causality is an abstraction that indicates how the world progresses. As such a basic concept, it is more apt as an explanation of other concepts of progression than as something to be explained by others more basic. The concept is like those of agency and efficacy. For this reason, a leap of intuition may be needed to grasp it. Accordin ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Karl Popper
Sir Karl Raimund Popper (28 July 1902 – 17 September 1994) was an Austrian-British philosopher, academic and social commentator. One of the 20th century's most influential philosophers of science, Popper is known for his rejection of the classical inductivist views on the scientific method in favour of empirical falsification. According to Popper, a theory in the empirical sciences can never be proven, but it can be falsified, meaning that it can (and should) be scrutinised with decisive experiments. Popper was opposed to the classical justificationist account of knowledge, which he replaced with critical rationalism, namely "the first non-justificational philosophy of criticism in the history of philosophy". In political discourse, he is known for his vigorous defence of liberal democracy and the principles of social criticism that he believed made a flourishing open society possible. His political philosophy embraced ideas from major democratic political ideologies, inc ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
David Hume
David Hume (; born David Home; 7 May 1711 NS (26 April 1711 OS) – 25 August 1776) Cranston, Maurice, and Thomas Edmund Jessop. 2020 999br>David Hume" ''Encyclopædia Britannica''. Retrieved 18 May 2020. was a Scottish Enlightenment philosopher, historian, economist, librarian, and essayist, who is best known today for his highly influential system of philosophical empiricism, scepticism, and naturalism. Beginning with '' A Treatise of Human Nature'' (1739–40), Hume strove to create a naturalistic science of man that examined the psychological basis of human nature. Hume argued against the existence of innate ideas, positing that all human knowledge derives solely from experience. This places him with Francis Bacon, Thomas Hobbes, John Locke, and George Berkeley as an Empiricist. Hume argued that inductive reasoning and belief in causality cannot be justified rationally; instead, they result from custom and mental habit. We never actually perceive that one event caus ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Prospective Study
A prospective cohort study is a longitudinal cohort study that follows over time a group of similar individuals (cohorts) who differ with respect to certain factors under study, to determine how these factors affect rates of a certain outcome. For example, one might follow a cohort of middle-aged truck drivers who vary in terms of smoking habits, to test the hypothesis that the 20-year incidence rate of lung cancer will be highest among heavy smokers, followed by moderate smokers, and then nonsmokers. The prospective study is important for research on the etiology of diseases and disorders. The distinguishing feature of a prospective cohort study is that at the time that the investigators begin enrolling subjects and collecting baseline exposure information, none of the subjects have developed any of the outcomes of interest. After baseline information is collected, subjects in a prospective cohort study are then followed "longitudinally," i.e. over a period of time, usually for ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
