Aurein
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Aurein
This family of antibacterial peptides are secreted from the granular dorsal glands of ''Litoria aurea'' (Green and golden bell frog), '' Litoria raniformis'' (Southern bell frog), '' Litoria citropa'' (Australian blue mountains tree frog) and frogs from genus Uperoleia. Amongst the more active of these are aurein 1.2, aurein 2.2 and aurein 3.1; caerin 1.1, maculatin 1.1, uperin 3.6; citropin 1.1, citropin 1.2, citropin 1.3 and a minor peptide are wide-spectrum antibacterial peptides Peptides (, ) are short chains of amino acids linked by peptide bonds. Long chains of amino acids are called proteins. Chains of fewer than twenty amino acids are called oligopeptides, and include dipeptides, tripeptides, and tetrapeptides. A p .... References {{InterPro content, IPR013157 Antimicrobial peptides Protein families ...
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Antimicrobial Peptides
Antimicrobial peptides (AMPs), also called host defence peptides (HDPs) are part of the innate immune response found among all classes of life. Fundamental differences exist between prokaryotic and eukaryotic cells that may represent targets for antimicrobial peptides. These peptides are potent, broad spectrum antibiotics which demonstrate potential as novel therapeutic agents. Antimicrobial peptides have been demonstrated to kill Gram negative and Gram positive bacteria, enveloped viruses, fungi and even transformed or cancerous cells. Unlike the majority of conventional antibiotics it appears that antimicrobial peptides frequently destabilize biological membranes, can form transmembrane channels, and may also have the ability to enhance immunity by functioning as immunomodulators. Structure Antimicrobial peptides are a unique and diverse group of molecules, which are divided into subgroups on the basis of their amino acid composition and structure. Antimicrobial peptides a ...
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Antibacterial
An antibiotic is a type of antimicrobial substance active against bacteria. It is the most important type of antibacterial agent for fighting bacterial infections, and antibiotic medications are widely used in the treatment and prevention of such infections. They may either kill or inhibit the growth of bacteria. A limited number of antibiotics also possess antiprotozoal activity. Antibiotics are not effective against viruses such as the common cold or influenza; drugs which inhibit viruses are termed antiviral drugs or antivirals rather than antibiotics. Sometimes, the term ''antibiotic''—literally "opposing life", from the Greek roots ἀντι ''anti'', "against" and βίος ''bios'', "life"—is broadly used to refer to any substance used against microbes, but in the usual medical usage, antibiotics (such as penicillin) are those produced naturally (by one microorganism fighting another), whereas non-antibiotic antibacterials (such as sulfonamides and anti ...
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Peptide
Peptides (, ) are short chains of amino acids linked by peptide bonds. Long chains of amino acids are called proteins. Chains of fewer than twenty amino acids are called oligopeptides, and include dipeptides, tripeptides, and tetrapeptides. A polypeptide is a longer, continuous, unbranched peptide chain. Hence, peptides fall under the broad chemical classes of biological polymers and oligomers, alongside nucleic acids, oligosaccharides, polysaccharides, and others. A polypeptide that contains more than approximately 50 amino acids is known as a protein. Proteins consist of one or more polypeptides arranged in a biologically functional way, often bound to ligands such as coenzymes and cofactors, or to another protein or other macromolecule such as DNA or RNA, or to complex macromolecular assemblies. Amino acids that have been incorporated into peptides are termed residues. A water molecule is released during formation of each amide bond.. All peptides except cyclic ...
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Secreted
440px Secretion is the movement of material from one point to another, such as a secreted chemical substance from a cell or gland. In contrast, excretion is the removal of certain substances or waste products from a cell or organism. The classical mechanism of cell secretion is via secretory portals at the plasma membrane called porosomes. Porosomes are permanent cup-shaped lipoprotein structures embedded in the cell membrane, where secretory vesicles transiently dock and fuse to release intra-vesicular contents from the cell. Secretion in bacterial species means the transport or translocation of effector molecules for example: proteins, enzymes or toxins (such as cholera toxin in pathogenic bacteria e.g. ''Vibrio cholerae'') from across the interior (cytoplasm or cytosol) of a bacterial cell to its exterior. Secretion is a very important mechanism in bacterial functioning and operation in their natural surrounding environment for adaptation and survival. In eukaryotic cells Me ...
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Dorsum (biology)
Standard anatomical terms of location are used to unambiguously describe the anatomy of animals, including humans. The terms, typically derived from Latin or Greek roots, describe something in its standard anatomical position. This position provides a definition of what is at the front ("anterior"), behind ("posterior") and so on. As part of defining and describing terms, the body is described through the use of anatomical planes and anatomical axes. The meaning of terms that are used can change depending on whether an organism is bipedal or quadrupedal. Additionally, for some animals such as invertebrates, some terms may not have any meaning at all; for example, an animal that is radially symmetrical will have no anterior surface, but can still have a description that a part is close to the middle ("proximal") or further from the middle ("distal"). International organisations have determined vocabularies that are often used as standard vocabularies for subdisciplines of an ...
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Litoria Aurea
The green and golden bell frog (''Ranoidea aurea''), also named the green bell frog, green and golden swamp frog and green frog, is a species of ground-dwelling tree frog native to eastern Australia. Despite its classification and climbing abilities, it does not live in trees and spends almost all of its time close to ground level. It can reach up to in length, making it one of Australia's largest frogs. Coloured gold and green, the frogs are voracious eaters of insects, but will also eat larger prey, such as worms and mice. They are mainly diurnal, although this is mostly to warm in the sun. They tend to be less active in winter except in warmer or wetter periods, and breed in the warmer months. Males reach maturity after around 9 months, while for the larger females, this does not occur until they are two years old. The frogs can engage in cannibalism, and males frequently attack and injure one another if they infringe on one another's space. Many populations, particularly ...
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Litoria Raniformis
The growling grass frog (''Ranoidea raniformis''), also commonly known as the southern bell frog, warty swamp frog and erroneously as the green frog, is a species of ground-dwelling tree frog native to southeastern Australia, ranging from southern South Australia along the Murray River though Victoria to New South Wales, with populations through Tasmania. This species' common names vary between states; the name southern bell frog applies to New South Wales, growling grass frog in Victoria and South Australia, and green and gold frog in Tasmania. This species has been introduced to New Zealand. Description The growling grass frog is a very large, ground-dwelling tree frog up to 10 cm (almost 4 in) from snout to vent. It is a mottled bright green and bronze colour above, often with dark brown enameled bumps. It has a pale cream underside, with a faint cobbling pattern. A pale stripe runs from the side of the head down the flanks as a skin fold. The thighs are blue-green in ...
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Litoria Citropa
The Blue Mountains tree frog (''Ranoidea citropa'') also called the variegated river tree frog is a species of tree frog in the subfamily Pelodryadinae. It is endemic to southeastern Australia and is found in eastern Victoria and in southeastern New South Wales. The Jenolan Caves tree frog, a population formerly separated as ''Litoria jenolanensis'', is nowadays included in this species. Description This is a moderate-sized frog, up to about in length. Its dorsal surface is brown with a few darker flecks. There is a dark stripe that runs from the nostril, above the tympanum, to the groin. There is a lighter golden stripe above and adjacent to the dark stripe. Their head, arms, legs, and the side of their body are green in colour. The amount of green on an individual frog can range from almost none at all to an all green colour morph. The green colour can occasionally be aqua-green. The armpit, thigh, groin, and inner section of the foot are bright red-orange in colour. The belly ...
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Genus
Genus ( plural genera ) is a taxonomic rank used in the biological classification of living and fossil organisms as well as viruses. In the hierarchy of biological classification, genus comes above species and below family. In binomial nomenclature, the genus name forms the first part of the binomial species name for each species within the genus. :E.g. '' Panthera leo'' (lion) and '' Panthera onca'' (jaguar) are two species within the genus ''Panthera''. ''Panthera'' is a genus within the family Felidae. The composition of a genus is determined by taxonomists. The standards for genus classification are not strictly codified, so different authorities often produce different classifications for genera. There are some general practices used, however, including the idea that a newly defined genus should fulfill these three criteria to be descriptively useful: # monophyly – all descendants of an ancestral taxon are grouped together (i.e. phylogenetic analysis should c ...
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Uperoleia
''Uperoleia'' is a genus of frogs in the family Myobatrachidae. They are native to northern and eastern Australia and southern lowlands of New Guinea. These are small squat frogs, more commonly known as "toadlets". They have glandular skin, often with a pair of raised glands behind each eye, or on the flanks. They have bumpy, rough skin giving them the appearance of a small toad, hence the name "toadlet", although they are often called "gungans" in Queensland. There are two distinct types of calls—''Uperoleia'' species make either a "click" or a "squelch". Generally, the "clicking" ''Uperoleia'' have long thin inguinal glands that run along the dorsal surface, while the "squelching" ''Uperoleia'' have round inguinal glands restricted to the posterior half of the dorsal surface. It is unusual to find more than one species of "clickers" or "squelchers" in the same location, although finding one of each is quite frequent in northern Australia. The species in this genus show great ...
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Peptides
Peptides (, ) are short chains of amino acids linked by peptide bonds. Long chains of amino acids are called proteins. Chains of fewer than twenty amino acids are called oligopeptides, and include dipeptides, tripeptides, and tetrapeptides. A polypeptide is a longer, continuous, unbranched peptide chain. Hence, peptides fall under the broad chemical classes of biological polymers and oligomers, alongside nucleic acids, oligosaccharides, polysaccharides, and others. A polypeptide that contains more than approximately 50 amino acids is known as a protein. Proteins consist of one or more polypeptides arranged in a biologically functional way, often bound to ligands such as coenzymes and cofactors, or to another protein or other macromolecule such as DNA or RNA, or to complex macromolecular assemblies. Amino acids that have been incorporated into peptides are termed residues. A water molecule is released during formation of each amide bond.. All peptides except cyclic pept ...
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