Ascarids
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Ascarids
''Parascaris equorum'' is a species of ascarid that is the equine roundworm. Amongst horse owners, the parasites are colloquially called "Ascarids". This is a host-specific helminth intestinal parasite that can infect horses, donkeys, and zebras. Horses up to six months of age are the most susceptible to infection. After this time, infection rates begin to decline and is extremely uncommon in horses over twelve months of age. It cannot infect humans or other animals. It is yellow-white in color, and females can become as large as in length. Found worldwide, ''P. equorum'' is one of the most difficult equine parasites to kill, requiring larger doses of more powerful anthelmintic medications than are needed for other equine parasites. Life cycle ''P. equorum'' is sexually dimorphic, the females are significantly larger than males. While males only grow up to 15–28 cm in length, the females can grow up to 50 cm in length. They are a white colored, cylindrical worm and ...
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Deworming
Deworming (sometimes known as worming, drenching or dehelmintization) is the giving of an anthelmintic drug (a wormer, dewormer, or drench) to a human or animals to rid them of helminths parasites, such as roundworm, flukes and tapeworm. Purge dewormers for use in livestock can be formulated as a feed supplement that is eaten, a paste or gel that is deposited at the back of the animal's mouth, a liquid drench given orally, an injectable, or as a pour-on which can be applied to the animal's topline. In dogs and cats, purge dewormers come in many forms including a granular form to be added to food, pill form, chew tablets, and liquid suspensions. Animals Large animal Horses are most often dewormed with a paste or gel placed on the back of the animal's mouth via a dosing syringe; feed dewormers are also used, both single-dose varieties and in a daily, "continuous" feed form. Deworming (drenching) a sheep is usually done with a specific drenching gun that squirts an anthelmi ...
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Deworming
Deworming (sometimes known as worming, drenching or dehelmintization) is the giving of an anthelmintic drug (a wormer, dewormer, or drench) to a human or animals to rid them of helminths parasites, such as roundworm, flukes and tapeworm. Purge dewormers for use in livestock can be formulated as a feed supplement that is eaten, a paste or gel that is deposited at the back of the animal's mouth, a liquid drench given orally, an injectable, or as a pour-on which can be applied to the animal's topline. In dogs and cats, purge dewormers come in many forms including a granular form to be added to food, pill form, chew tablets, and liquid suspensions. Animals Large animal Horses are most often dewormed with a paste or gel placed on the back of the animal's mouth via a dosing syringe; feed dewormers are also used, both single-dose varieties and in a daily, "continuous" feed form. Deworming (drenching) a sheep is usually done with a specific drenching gun that squirts an anthelmi ...
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Horse Colic
Colic in horses is defined as abdominal pain, but it is a clinical symptom rather than a diagnosis. The term colic can encompass all forms of gastrointestinal conditions which cause pain as well as other causes of abdominal pain not involving the gastrointestinal tract. The most common forms of colic are gastrointestinal in nature and are most often related to colonic disturbance. There are a variety of different causes of colic, some of which can prove fatal without surgical intervention. Colic surgery is usually an expensive procedure as it is major abdominal surgery, often with intensive aftercare. Among domesticated horses, colic is the leading cause of premature death. The incidence of colic in the general horse population has been estimated between 4 and 10 percent over the course of the average lifespan. Clinical signs of colic generally require treatment by a veterinarian. The conditions that cause colic can become life-threatening in a short period of time. Pathophysiolog ...
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Ascaris
''Ascaris'' is a genus of parasite, parasitic nematode worms known as the "small intestinal roundworms", which is a type of parasitic worm. One species, ''Ascaris lumbricoides'', affects humans and causes the disease ascariasis. Another species, ''Ascaris suum'', typically infects pigs. ''Parascaris equorum'', the equine roundworm, is also commonly called an "ascarid". Their eggs are deposited in feces and soil. Plants with the eggs on them infect any organism that consumes them. ''A. lumbricoides'' is the largest intestinal roundworm and is the most common helminth infection of humans worldwide. Infestation can cause morbidity by compromising nutritional status, affecting cognitive processes, inducing tissue reactions such as granuloma to larval stages, and by causing intestinal obstruction, which can be fatal. Morphology * Adult: cylindrical shape, creamy white or pinkish in color * Male: average 15–30 cm (6–12 inches); more slender than the female * Female: average ...
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Helminth
Parasitic worms, also known as helminths, are large macroparasites; adults can generally be seen with the naked eye. Many are intestinal worms that are soil-transmitted and infect the gastrointestinal tract. Other parasitic worms such as schistosomes reside in blood vessels. Some parasitic worms, including leeches and monogeneans, are ectoparasites thus, they are not classified as helminths, which are endoparasites. Parasitic worms live in and feed in living hosts. They receive nourishment and protection while disrupting their hosts' ability to absorb nutrients. This can cause weakness and disease in the host, and poses a global health and economic problem. Parasitic worms cannot reproduce entirely within their host's body; they have a life cycle that includes some stages that need to take place outside of the host. Helminths are able to survive in their mammalian hosts for many years due to their ability to manipulate the host's immune response by secreting immunomodulatory ...
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Macrocyclic
Macrocycles are often described as molecules and ions containing a ring of twelve or more atoms. Classical examples include the crown ethers, calixarenes, porphyrins, and cyclodextrins. Macrocycles describe a large, mature area of chemistry. Synthesis The formation of macrocycles by ring-closure is called macrocylization. Pioneering work was reported for studies on terpenoid macrocycles. The central challenge to macrocyclization is that ring-closing reactions do not favor the formation of large rings. Instead, small rings or polymers tend to form. This kinetic problem can be addressed by using high-dilution reactions, whereby intramolecular processes are favored relative to polymerizations. Some macrocyclizations are favored using template reactions. Templates are ions, molecules, surfaces etc. that bind and pre-organize compounds, guiding them toward formation of a particular ring size. The crown ethers are often generated in the presence of an alkali metal cation, whic ...
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Stable
A stable is a building in which livestock, especially horses, are kept. It most commonly means a building that is divided into separate stalls for individual animals and livestock. There are many different types of stables in use today; the American-style barn, for instance, is a large barn with a door at each end and individual stalls inside or free-standing stables with top and bottom-opening doors. The term "stable" is also used to describe a group of animals kept by one owner, regardless of housing or location. The exterior design of a stable can vary widely, based on climate, building materials, historical period and cultural styles of architecture. A wide range of building materials can be used, including masonry (bricks or stone), wood and steel. Stables also range widely in size, from a small building housing one or two animals to facilities at agricultural shows or race tracks that can house hundreds of animals. History The stable is typically historically the se ...
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Pasture
Pasture (from the Latin ''pastus'', past participle of ''pascere'', "to feed") is land used for grazing. Pasture lands in the narrow sense are enclosed tracts of farmland, grazed by domesticated livestock, such as horses, cattle, sheep, or swine. The vegetation of tended pasture, forage, consists mainly of grasses, with an interspersion of legumes and other forbs (non-grass herbaceous plants). Pasture is typically grazed throughout the summer, in contrast to meadow which is ungrazed or used for grazing only after being mown to make hay for animal fodder. Pasture in a wider sense additionally includes rangelands, other unenclosed pastoral systems, and land types used by wild animals for grazing or browsing. Pasture lands in the narrow sense are distinguished from rangelands by being managed through more intensive agricultural practices of seeding, irrigation, and the use of fertilizers, while rangelands grow primarily native vegetation, managed with extensive practices like co ...
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Trichlorfon
Metrifonate (INN) or trichlorfon (USAN) is an irreversible organophosphate acetylcholinesterase inhibitor. It is a prodrug which is activated non-enzymatically into the active agent dichlorvos. It is used as an insecticide. According to the US Environmental Protection Agency trichlorfon has been used on golf course turf, home lawns, non-food contact areas of food and meat processing plants, ornamental shrubs and plants, and ornamental and baitfish ponds. Used to control caterpillars, white grubs, mole crickets, cattle lice, sod webworms, leaf miners, stink bugs, flies, ants, cockroaches, earwigs, crickets, diving beetle, water scavenger beetle, water boatman backswimmer, water scorpions, giant water bugs and pillbugs. After reregistration, a number of its uses were voluntarily restricted, and currently, it is used in nonfood areas to control flies, roaches, and ants among other pets. Outdoors it is used on ornamental plants, golf courses, and lawn grass to treat lepidopteran ...
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Dichlorvos
Dichlorvos (2,2-dichlorovinyl dimethyl phosphate, commonly abbreviated as an DDVP) is an organophosphate widely used as an insecticide to control household pests, in public health, and protecting stored products from insects. The compound has been commercially available since 1961 and has become controversial because of its prevalence in urban waterways and the fact that its toxicity extends well beyond insects. Since 1988, dichlorvos cannot be used as a plant protection product in the EU. Use Dichlorvos is effective against mushroom flies, aphids, spider mites, caterpillars, thrips, and whiteflies in greenhouses and in outdoor crops. It is also used in the milling and grain handling industries and to treat a variety of parasitic worm infections in animals and humans. It is fed to livestock to control botfly larvae in manure. It acts against insects as both a contact poison and an ingested poison. It is available as an aerosol and soluble concentrate. It is also used in pet flea ...
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Piperazine
Piperazine () is an organic compound that consists of a six-membered ring containing two nitrogen atoms at opposite positions in the ring. Piperazine exists as small alkaline deliquescent crystals with a saline taste. The piperazines are a broad class of chemical compounds, many with important pharmacological properties, which contain a core piperazine functional group. Origin and naming Piperazines were originally named because of their chemical similarity with piperidine, part of the structure of piperine in the black pepper plant (''Piper nigrum''). The -az- infix added to "piperazine" refers to the extra nitrogen atom, compared to piperidine. It is important to note, however, that piperazines are ''not'' derived from plants in the '' Piper'' genus. Chemistry Piperazine is freely soluble in water and ethylene glycol, but insoluble in diethyl ether. It is a weak base with two pKb of 5.35 and 9.73 at 25 °C.; the pH of a 10% aqueous solution of piperazine is 10.8–11.8. Pi ...
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Pyrantel Pamoate
Pyrantel is a medication used to treat a number of parasitic worm infections. This includes ascariasis, hookworm infections, enterobiasis (pinworm infection), trichostrongyliasis, and trichinellosis. It is taken by mouth. Side effects include nausea, headache, dizziness, trouble sleeping, and rash. A lower dose should be used in people with liver disease. While it does not appear to be harmful during pregnancy, it has not been studied for this use. It is unclear if it is safe for use during breastfeeding. It is in the antihelmintic family of medications. It works by paralyzing worms. Pyrantel was initially described in 1965. It is on the World Health Organization's List of Essential Medicines. Pyrantel is available as a generic medication. It may also be used to treat worms in a number of other animals. Pregnancy and breastfeeding Pyrantel pamoate is considered a pregnancy category C drug for use during pregnancy for humans, but is in category A for canines and felines. Pyr ...
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