Arthur Hill Hassall
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Arthur Hill Hassall
Arthur Hill Hassall (13 December 1817, Teddington – 9 April 1894, San Remo) was a British physician, chemist and microscopist who is primarily known for his work in public health and food safety. Biography Hassall was born in Middlesex as the youngest son of five children in a house of a surgeon. His father was Thomas Hassall (1771–1844) and his mother, née Ann Sherrock ( 1778–1817). He spent his school years in Richmond. He entered medicine through apprenticeship in 1834 to his uncle Sir James Murray (1788–1871), spending his early career in Dublin, where he also studied botany and the seashore. In 1846 he published a two-volume study, ''The Microscopic Anatomy of the Human Body in Health and Disease'', the first English textbook on the subject. After further studying botany at Kew and publishing on botanical topics, particularly freshwater algae, he came to public attention with his 1850 book ''A microscopical examination of the water supplied to the inhabitants of ...
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Arthur Hill Hassall
Arthur Hill Hassall (13 December 1817, Teddington – 9 April 1894, San Remo) was a British physician, chemist and microscopist who is primarily known for his work in public health and food safety. Biography Hassall was born in Middlesex as the youngest son of five children in a house of a surgeon. His father was Thomas Hassall (1771–1844) and his mother, née Ann Sherrock ( 1778–1817). He spent his school years in Richmond. He entered medicine through apprenticeship in 1834 to his uncle Sir James Murray (1788–1871), spending his early career in Dublin, where he also studied botany and the seashore. In 1846 he published a two-volume study, ''The Microscopic Anatomy of the Human Body in Health and Disease'', the first English textbook on the subject. After further studying botany at Kew and publishing on botanical topics, particularly freshwater algae, he came to public attention with his 1850 book ''A microscopical examination of the water supplied to the inhabitants of ...
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Education In Chemistry
''Education in Chemistry'' (often referred to by its brand 'EiC') is a print and online magazine covering all areas of chemistry education, mainly concentrating on the teaching of chemistry in secondary schools and university, universities. It is published by the Royal Society of Chemistry, which also publishes ''Chemistry Education Research and Practice'', a peer-reviewed academic journal on the same topic. History The feasibility of a "British Journal of Chemistry Education" was first discussed by the Royal Society of Chemistry in late 1962 (a similar journal, the ''Journal of Chemical Education'' had been in existence in the USA since 1924). Its launch was secured by the lobbying of Professor Ronald Sydney Nyholm, Ronald S. Nyholm who became the first Chair of the editorial board. The magazine was launched in 1963 under the editor Dr F. W. Gibbs with the first issue published in January 1964. Gibbs' first editorial, "Scientists and Teachers", set out the aims of the publicatio ...
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Thymus Gland
The thymus is a specialized primary lymphoid organ of the immune system. Within the thymus, thymus cell lymphocytes or ''T cells'' mature. T cells are critical to the adaptive immune system, where the body adapts to specific foreign invaders. The thymus is located in the upper front part of the chest, in the anterior superior mediastinum, behind the sternum, and in front of the heart. It is made up of two lobes, each consisting of a central medulla and an outer cortex, surrounded by a capsule. The thymus is made up of immature T cells called thymocytes, as well as lining cells called epithelial cells which help the thymocytes develop. T cells that successfully develop react appropriately with MHC immune receptors of the body (called ''positive selection'') and not against proteins of the body (called ''negative selection''). The thymus is largest and most active during the neonatal and pre-adolescent periods. By the early teens, the thymus begins to decrease in size and act ...
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Thymus
The thymus is a specialized primary lymphoid organ of the immune system. Within the thymus, thymus cell lymphocytes or ''T cells'' mature. T cells are critical to the adaptive immune system, where the body adapts to specific foreign invaders. The thymus is located in the upper front part of the chest, in the anterior superior mediastinum, behind the sternum, and in front of the heart. It is made up of two lobes, each consisting of a central medulla and an outer cortex, surrounded by a capsule. The thymus is made up of immature T cells called thymocytes, as well as lining cells called epithelial cells which help the thymocytes develop. T cells that successfully develop react appropriately with MHC immune receptors of the body (called ''positive selection'') and not against proteins of the body (called ''negative selection''). The thymus is largest and most active during the neonatal and pre-adolescent periods. By the early teens, the thymus begins to decrease in size and a ...
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Hassall's Corpuscles
Hassall's corpuscles (or thymic corpuscles (bodies)) are structures found in the medulla of the human thymus, formed from eosinophilic type VI epithelial reticular cells arranged concentrically. These concentric corpuscles are composed of a central mass, consisting of one or more granular cells, and of a capsule formed of epithelioid cells. They vary in size with diameters from 20 to more than 100μm, and tend to grow larger with age. They can be spherical or ovoid and their epithelial cells contain keratohyalin and bundles of cytoplasmic fibres. Later studies indicate that Hassall's corpuscles differentiate from medullary thymic epithelial cells after they lose autoimmune regulator (AIRE) expression. They are named for Arthur Hill Hassall, who discovered them in 1846. The function of Hassall's corpuscles is currently unclear, and the absence of this structure in the thymus of most murine species (except for the New Zealand White Mouse strain) has previously restricted mechanistic ...
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Lucerne
Lucerne ( , ; High Alemannic German, High Alemannic: ''Lozärn'') or Luzern ()Other languages: gsw, Lozärn, label=Lucerne German; it, Lucerna ; rm, Lucerna . is a city in central Switzerland, in the Languages of Switzerland, German-speaking portion of the country. Lucerne is the capital of the canton of Lucerne and part of the Lucerne (district), district of the same name. With a population of approximately 82,000 people, Lucerne is List of cities in Switzerland, the most populous city in Central Switzerland, and a nexus of economics, transportation, culture, and media in the region. The city's urban area consists of 19 municipalities and towns with an overall population of about 220,000 people. Owing to its location on the shores of Lake Lucerne (german: Vierwaldstättersee) and its outflow, the river Reuss (river), Reuss, within sight of the mounts Pilatus (mountain), Pilatus and Rigi in the Swiss Alps, Lucerne has long been a destination for tourists. One of the city's landm ...
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Thomas Hellyer (architect)
Thomas Hellyer (1811–18 March 1894) was an English architect of the mid-Victorian era. He was based on the Isle of Wight and was "the leading Island-based architect of the period", but his works can also be found on the mainland—principally in Hampshire—but also further afield. Described by Pevsner as a "very individualistic" and "remarkable" architect, his output included churches, houses, schools and hospitals across the island, during a period of rapid urban development. Many of his buildings have listed status and he "made important contributions to the appearance of the city" of Portsmouth through his extensive work in the area. Biography Thomas Hellyer was born in Emsworth, a Hampshire village close to the Sussex border, in 1811. He was married to Harriet, originally from Portsea, and they had one daughter, also called Harriet. His wife predeceased him. Much of Hellyer's early architectural work involved church design and restoration on the Isle of Wight, wher ...
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Ventnor
Ventnor () is a seaside resort and civil parish established in the Victorian era on the southeast coast of the Isle of Wight, England, from Newport. It is situated south of St Boniface Down, and built on steep slopes leading down to the sea. The higher part is referred to as Upper Ventnor (officially Lowtherville); the lower part, where most amenities are located, is known as Ventnor. Ventnor is sometimes taken to include the nearby and older settlements of St Lawrence and Bonchurch, which are covered by its town council. The population of the parish in 2016 was about 5,800. Ventnor became extremely fashionable as both a health and holiday resort in the late 19th century, described as the 'English Mediterranean' and 'Mayfair by the Sea'. Medical advances during the early twentieth century reduced its role as a health resort and, like other British seaside resorts, its summer holiday trade suffered from the changing nature of travel during the latter part of the century. Its ...
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Sanatorium
A sanatorium (from Latin '' sānāre'' 'to heal, make healthy'), also sanitarium or sanitorium, are antiquated names for specialised hospitals, for the treatment of specific diseases, related ailments and convalescence. Sanatoriums are often located in a healthy climate, usually in the countryside. The idea of healing was an important reason for the historical wave of establishments of sanatoriums, especially at the end of the 19th- and early 20th centuries. One sought for instance the healing of consumptives, especially tuberculosis (before the discovery of antibiotics) or alcoholism, but also of more obscure addictions and longings, of hysteria, masturbation, fatigue and emotional exhaustion. Facility operators were often charitable associations such as the Order of St. John and the newly founded social welfare insurance companies. Sanatoriums should not be confused with the Russian sanatoriums from the time of the Soviet Union, which were a type of sanatorium resort r ...
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Undercliff (Isle Of Wight)
The Undercliff, Isle of Wight, England is a tract of semi-rural land, around long by wide, skirting the southern coast of the island from Niton to Bonchurch. Named after its position below the escarpment that backs this coastal section, its undulating terrain comprises a mix of rough pasture, secondary woodland, parkland, grounds of large isolated houses, and suburban development. Its sheltered south-facing location gives rise to a microclimate considerably warmer than elsewhere on the island. Although inhabited, the Undercliff is an area prone to landslips and subsidence, with accompanying loss of property over time. Settlements along the Undercliff, from west to east, are: lower Niton (also called Niton Undercliff), Puckaster, St Lawrence, Steephill, the town of Ventnor, and Bonchurch. Geology The Undercliff is a landslide complex in Cretaceous soft rocks, a bench of slipped clays and sands above a low sea-cliff, backed by higher () Upper Greensand and Chalk cliffs. ...
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Microclimate
A microclimate (or micro-climate) is a local set of atmospheric conditions that differ from those in the surrounding areas, often with a slight difference but sometimes with a substantial one. The term may refer to areas as small as a few square meters or square feet (for example a garden bed or a cave) or as large as many square kilometers or square miles. Because climate is statistical, which implies spatial and temporal variation of the mean values of the describing parameters, within a region there can occur and persist over time sets of statistically distinct conditions, that is, microclimates. Microclimates can be found in most places but are most pronounced in topographically dynamic zones such as mountainous areas, islands, coastal areas. Microclimates exist, for example, near bodies of water which may cool the local atmosphere, or in heavy urban areas where brick, concrete, and asphalt absorb the sun's energy, heat up, and re-radiate that heat to the ambient air: t ...
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Isle Of Wight
The Isle of Wight ( ) is a county in the English Channel, off the coast of Hampshire, from which it is separated by the Solent. It is the largest and second-most populous island of England. Referred to as 'The Island' by residents, the Isle of Wight has resorts that have been popular holiday destinations since Victorian times. It is known for its mild climate, coastal scenery, and verdant landscape of fields, downland and chines. The island is historically part of Hampshire, and is designated a UNESCO Biosphere Reserve. The island has been home to the poets Algernon Charles Swinburne and Alfred, Lord Tennyson. Queen Victoria built her summer residence and final home, Osborne House at East Cowes, on the Isle. It has a maritime and industrial tradition of boat-building, sail-making, the manufacture of flying boats, hovercraft, and Britain's space rockets. The island hosts annual music festivals, including the Isle of Wight Festival, which in 1970 was the largest rock music ...
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