Armed Forces Research Institute Of Medical Sciences
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Armed Forces Research Institute Of Medical Sciences
The Armed Forces Research Institute of Medical Sciences (AFRIMS) ( th, สถาบันวิจัยวิทยาศาสตร์การแพทย์ทหาร, link=no) is a United States Army project that started as a collaboration with the Government of Thailand to fight a cholera outbreak in Bangkok in 1958 and 1959. It subsequently expanded to conduct military medical research, primarily involving infectious diseases, across much of Southeast Asia and the Indian Subcontinent. Mission and history The mission of the US Army Medical Component of the Armed Forces Research Institute of the Medical Sciences (USAMC-AFRIMS) is to conduct basic and applied research for development of diagnostic tests, drugs and vaccines for infectious diseases of military importance. First formed as the SEATO Laboratory following the 1956–1958 cholera pandemic, USAMC-AFRIMS is an agency of the US Embassy Thailand residing at the Royal Thai Army Medical Center in Bangkok. AFRIMS is a spe ...
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United States Army
The United States Army (USA) is the land service branch of the United States Armed Forces. It is one of the eight U.S. uniformed services, and is designated as the Army of the United States in the U.S. Constitution.Article II, section 2, clause 1 of the United States Constitution (1789). See alsTitle 10, Subtitle B, Chapter 301, Section 3001 The oldest and most senior branch of the U.S. military in order of precedence, the modern U.S. Army has its roots in the Continental Army, which was formed 14 June 1775 to fight the American Revolutionary War (1775–1783)—before the United States was established as a country. After the Revolutionary War, the Congress of the Confederation created the United States Army on 3 June 1784 to replace the disbanded Continental Army.Library of CongressJournals of the Continental Congress, Volume 27/ref> The United States Army considers itself to be a continuation of the Continental Army, and thus considers its institutional inception to be th ...
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United States Army Medical Research And Materiel Command
United may refer to: Places * United, Pennsylvania, an unincorporated community * United, West Virginia, an unincorporated community Arts and entertainment Films * ''United'' (2003 film), a Norwegian film * ''United'' (2011 film), a BBC Two film Literature * ''United!'' (novel), a 1973 children's novel by Michael Hardcastle Music * United (band), Japanese thrash metal band formed in 1981 Albums * ''United'' (Commodores album), 1986 * ''United'' (Dream Evil album), 2006 * ''United'' (Marvin Gaye and Tammi Terrell album), 1967 * ''United'' (Marian Gold album), 1996 * ''United'' (Phoenix album), 2000 * ''United'' (Woody Shaw album), 1981 Songs * "United" (Judas Priest song), 1980 * "United" (Prince Ital Joe and Marky Mark song), 1994 * "United" (Robbie Williams song), 2000 * "United", a song by Danish duo Nik & Jay featuring Lisa Rowe Television * ''United'' (TV series), a 1990 BBC Two documentary series * ''United!'', a soap opera that aired on BBC One from 1965-19 ...
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Military Installations Of The United States In Thailand
A military, also known collectively as armed forces, is a heavily armed, highly organized force primarily intended for warfare. It is typically authorized and maintained by a sovereign state, with its members identifiable by their distinct military uniform. It may consist of one or more military branches such as an army, navy, air force, space force, marines, or coast guard. The main task of the military is usually defined as defence of the state and its interests against external armed threats. In broad usage, the terms ''armed forces'' and ''military'' are often treated as synonymous, although in technical usage a distinction is sometimes made in which a country's armed forces may include both its military and other paramilitary forces. There are various forms of irregular military forces, not belonging to a recognized state; though they share many attributes with regular military forces, they are less often referred to as simply ''military''. A nation's military may f ...
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Military Medicine In The United States
A military, also known collectively as armed forces, is a heavily armed, highly organized force primarily intended for warfare. It is typically authorized and maintained by a sovereign state, with its members identifiable by their distinct military uniform. It may consist of one or more military branches such as an army, navy, air force, space force, marines, or coast guard. The main task of the military is usually defined as defence of the state and its interests against external armed threats. In broad usage, the terms ''armed forces'' and ''military'' are often treated as synonymous, although in technical usage a distinction is sometimes made in which a country's armed forces may include both its military and other paramilitary forces. There are various forms of irregular military forces, not belonging to a recognized state; though they share many attributes with regular military forces, they are less often referred to as simply ''military''. A nation's military may f ...
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Association For Assessment And Accreditation Of Laboratory Animal Care International
The Association for Assessment and Accreditation of Laboratory Animal Care International, or AAALAC, is a private, nonprofit organization that promotes the humane treatment of animals in science through voluntary accreditation and assessment programs. The program started in 1965, when leading veterinarians and researchers organized the American Association for Accreditation of Laboratory Animal Care, or AAALAC. In 1996, AAALAC changed its name to the Association for Assessment and Accreditation of Laboratory Animal Care International (AAALAC International). The name change reflects the organization's growth in other countries, and its commitment to enhancing life sciences and quality animal care around the world. Today, more than 900 organizations worldwide are accredited. Along with meeting all applicable local and national regulations, AAALAC accredited institutions must also demonstrate that they are achieving the standards outlined in the Guide for the Care and Use of Laborator ...
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Halofantrine
Halofantrine is a drug used to treat malaria. Halofantrine's structure contains a substituted phenanthrene, and is related to the antimalarial drugs quinine and lumefantrine. Marketed as Halfan, halofantrine is never used to prevent malaria and its mode of action is unknown, although a crystallographic study showed that it binds to hematin ''in vitro'', suggesting a possible mechanism of action. Halofantrine has also been shown to bind to plasmepsin, a haemoglobin degrading enzyme unique to the malarial parasites. Halofantrine was developed at SRI International for the Walter Reed Army Institute of Research from 1965 to 1975 by a team led by medicinal chemist William Colwell. Adverse reactions Halofantrine can cause abdominal pain, diarrhoea, vomiting, rash, headache, itching and elevated liver enzymes. It can be associated with cardiotoxicity. The most dangerous side effect is cardiac arrhythmias: halofantrine causes significant QT prolongation, and this effect is seen even at ...
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Scrub Typhus
Scrub typhus or bush typhus is a form of typhus caused by the intracellular parasite ''Orientia tsutsugamushi'', a Gram-negative α-proteobacterium of family Rickettsiaceae first isolated and identified in 1930 in Japan.Pediatric Scrub Typhus
accessdate: 16 October 2011
Although the disease is similar in presentation to other forms of , its is no longer included in ''

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Dengue Fever
Dengue fever is a mosquito-borne tropical disease caused by the dengue virus. Symptoms typically begin three to fourteen days after infection. These may include a high fever, headache, vomiting, muscle and joint pains, and a characteristic skin itching and skin rash. Recovery generally takes two to seven days. In a small proportion of cases, the disease develops into a more severe dengue hemorrhagic fever, resulting in bleeding, low levels of blood platelets and blood plasma leakage, or into dengue shock syndrome, where dangerously low blood pressure occurs. Dengue is spread by several species of female mosquitoes of the ''Aedes'' genus, principally ''Aedes aegypti''. The virus has five serotypes; infection with one type usually gives lifelong immunity to that type, but only short-term immunity to the others. Subsequent infection with a different type increases the risk of severe complications. A number of tests are available to confirm the diagnosis including detecti ...
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Drug Resistant
Drug resistance is the reduction in effectiveness of a medication such as an antimicrobial or an antineoplastic in treating a disease or condition. The term is used in the context of resistance that pathogens or cancers have "acquired", that is, resistance has evolved. Antimicrobial resistance and antineoplastic resistance challenge clinical care and drive research. When an organism is resistant to more than one drug, it is said to be multidrug-resistant. The development of antibiotic resistance in particular stems from the drugs targeting only specific bacterial molecules (almost always proteins). Because the drug is ''so'' specific, any mutation in these molecules will interfere with or negate its destructive effect, resulting in antibiotic resistance. Furthermore, there is mounting concern over the abuse of antibiotics in the farming of livestock, which in the European Union alone accounts for three times the volume dispensed to humans – leading to development of super-resis ...
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Walter Reed Army Institute Of Research
The Walter Reed Army Institute of Research (WRAIR) is the largest biomedical research facility administered by the U.S. Department of Defense (DoD). The institute is centered at the Forest Glen Annex, in the Forest Glen Park part of the unincorporated Silver Spring urban area in Maryland just north of Washington, DC, but it is a subordinate unit of the U.S. Army Medical Research and Development Command (USAMRDC), headquartered at nearby Fort Detrick, Maryland. At Forest Glen, the WRAIR has shared a laboratory and administrative facility — the Sen Daniel K. Inouye Building, also known as Building 503 — with the Naval Medical Research Center since 1999. The Institute takes its name from Major (United States), Major Walter Reed, MD (1851–1902), the Army physician who, in 1901, led the team that confirmed the theory that yellow fever is transmitted by a particular mosquito species, rather than by direct contact. Today, the WRAIR fosters and performs biomedical research ...
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Government Of Thailand
The Government of Thailand, or formally the Royal Thai Government ( Abrv: RTG; th, รัฐบาลไทย, , ), is the unitary government of the Kingdom of Thailand. The country emerged as a modern nation state after the foundation of the Chakri Dynasty and the city of Bangkok in 1782. The Revolution of 1932 brought an end to absolute monarchy and replaced it with a constitutional monarchy. From then on the country was ruled by a succession of military leaders installed after coups d'état, the most recent in May 2014, and a few democratic intervals. The 2007 Constitution (drafted by a military-appointed council, but approved by a referendum) was annulled by the 2014 coup-makers who ran the country as a military dictatorship. Thailand has so far had seventeen Constitutions. Throughout, the basic structure of government has remained the same. The government of Thailand is composed of three branches: the executive, the legislative, and the judiciary. The system of gov ...
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SEATO
The Southeast Asia Treaty Organization (SEATO) was an international organization for collective defense in Southeast Asia created by the Southeast Asia Collective Defense Treaty, or Manila Pact, signed in September 1954 in Manila, the Philippines. The formal institution of SEATO was established on 19 February 1955 at a meeting of treaty partners in Bangkok, Thailand. The organization's headquarters was also in Bangkok. Eight members joined the organization. Primarily created to block further communist gains in Southeast Asia, SEATO is generally considered a failure because internal conflict and dispute hindered general use of the SEATO military; however, SEATO-funded cultural and educational programs left longstanding effects in Southeast Asia. SEATO was dissolved on 30 June 1977 after many members lost interest and withdrew. Origins and structure The Southeast Asia Collective Defense Treaty, or Manila Pact, was signed on 8 September 1954 in Manila, as part of the American T ...
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