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Aquamid
Aquamid is a non-absorbable soft volume filler for aesthetic and reconstructive purposes. Aquamid is the trade name for a specific formulation of 97.5% water for injection and 2.5% cross-linked polyacrylamide. It is injected subcutaneously to correct wrinkles and folds or to add volume. Common aesthetic indications are nasolabial folds, lip augmentation, cheek contouring, nose enhancement. Aquamid is also used to correct signs of facial lipoatrophy or fat wasting in HIV+ patients. Aquamid has been evaluated in several clinical trials involving more than 5,000 patients including a comparative trial in the United States. Data from this trial has been used to support a PMA application to the FDA The United States Food and Drug Administration (FDA or US FDA) is a federal agency of the Department of Health and Human Services. The FDA is responsible for protecting and promoting public health through the control and supervision of food s .... Aquamid is not yet approved for sale in t ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Polyacrylamide
Polyacrylamide (abbreviated as PAM) is a polymer with the formula (-CH2CHCONH2-). It has a linear-chain structure. PAM is highly water-absorbent, forming a soft gel when hydrated. In 2008, an estimated 750,000,000 kg were produced, mainly for water treatment and the paper and mineral industries. Physicochemical properties Polyacrylamide is a polyolefin. It can be viewed as polyethylene with amide substituents on alternating carbons. Unlike various nylons, polyacrylamide is not a polyamide because the amide groups are not in the polymer backbone. Owing to the presence of the amide (CONH2) groups, alternating carbon atoms in the backbone are stereogenic (colloquially: chiral). For this reason, polyacrylamide exists in atactic, syndiotactic, and isotactic forms, although this aspect is rarely discussed. The polymerization is initiated with radicals and is assumed to be stereorandom. Copolymers and modified polymers Linear polyacrylamide is a water-soluble polymer. Other p ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Subcutaneous Tissue
The subcutaneous tissue (), also called the hypodermis, hypoderm (), subcutis, superficial fascia, is the lowermost layer of the integumentary system in vertebrates. The types of cells found in the layer are fibroblasts, adipose cells, and macrophages. The subcutaneous tissue is derived from the mesoderm, but unlike the dermis, it is not derived from the mesoderm's dermatome region. It consists primarily of loose connective tissue, and contains larger blood vessels and nerves than those found in the dermis. It is a major site of fat storage in the body. In arthropods, a hypodermis can refer to an epidermal layer of cells that secretes the chitinous cuticle. The term also refers to a layer of cells lying immediately below the epidermis of plants. Structure * Fibrous bands anchoring the skin to the deep fascia * Collagen and elastin fibers attaching it to the dermis * Fat is absent from the eyelids, clitoris, penis, much of pinna, and scrotum * Blood vessels on route to the der ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Wrinkle
A wrinkle, also known as a rhytid, is a fold, ridge or crease in an otherwise smooth surface, such as on skin or fabric. Skin wrinkles typically appear as a result of ageing processes such as glycation, habitual sleeping positions, loss of body mass, sun damage, or temporarily, as the result of prolonged immersion in water. Age wrinkling in the skin is promoted by habitual facial expressions, aging, sun damage, smoking, poor hydration, and various other factors. In humans, it can also be prevented to some degree by avoiding excessive solar exposure and through diet (in particular through consumption of carotenoids, tocopherols and flavonoids, vitamins (A, C, D and E), essential omega-3-fatty acids, certain proteins and lactobacilli). Skin Causes for aging wrinkles Development of facial wrinkles is a kind of fibrosis of the skin. Misrepair-accumulation aging theory suggests that wrinkles develop from incorrect repairs of injured elastic fibers and collagen fibers. Repea ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Nasolabial Folds
The nasolabial folds, commonly known as "smile lines" or "laugh lines", are facial features. They are the two skin folds that run from each side of the nose to the corners of the mouth. They are defined by facial structures that support the buccal fat pad. They separate the cheeks from the upper lip. The term derives from Latin '' nasus'' for "nose" and '' labium'' for "lip". Nasolabial fold is a misnomer, however. The proper anatomical term is melolabial fold, meaning the fold between the cheek and lip. Cosmetology issues With ageing the fold may grow in length and depth. Dermal fillings may be used to replace lost fats and collagen in this facial area. Facial exercises give effective results in erasing the appearance of nasolabial folds. See also *Epicanthal fold *Nasalis muscle The nasalis muscle is a sphincter-like muscle of the nose. It has a transverse part and an alar part. It compresses the nasal cartilages, and can "flare" the nostrils. Some people can use it to clos ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Lip Enhancement
Lip augmentation is a cosmetic procedure that modifies the shape of the lips using fillers, such as collagen or implants. The procedure may be performed to increase lip size, correct asymmetry, create protrusion, or adjust the ratio of the top and bottom lips. The procedure typically involves surgical injection, though temporary non-surgical alternatives exist. Swelling and bruising are common after lip augmentation, and irritation or allergic reaction may also occur. Lip augmentations can have undesired cosmetic effects, including scarring and lumping, and implants pose the risk of shifting underneath the lip or breaking through the skin. History Around 1900, surgeons tried injecting paraffin into the lips without success. Liquid silicone was used for lip augmentation, starting in the early 1960s but was abandoned thirty years later due to fears about the effects of silicone on general health and long term aesthetic outcome. About 1980, injectable bovine collagen was intro ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Clinical Trial
Clinical trials are prospective biomedical or behavioral research studies on human participants designed to answer specific questions about biomedical or behavioral interventions, including new treatments (such as novel vaccines, drugs, dietary choices, dietary supplements, and medical devices) and known interventions that warrant further study and comparison. Clinical trials generate data on dosage, safety and efficacy. They are conducted only after they have received health authority/ethics committee approval in the country where approval of the therapy is sought. These authorities are responsible for vetting the risk/benefit ratio of the trial—their approval does not mean the therapy is 'safe' or effective, only that the trial may be conducted. Depending on product type and development stage, investigators initially enroll volunteers or patients into small pilot studies, and subsequently conduct progressively larger scale comparative studies. Clinical trials can vary i ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Food And Drug Administration
The United States Food and Drug Administration (FDA or US FDA) is a List of United States federal agencies, federal agency of the United States Department of Health and Human Services, Department of Health and Human Services. The FDA is responsible for protecting and promoting public health through the control and supervision of food safety, tobacco products, caffeine products, dietary supplements, Prescription drug, prescription and Over-the-counter drug, over-the-counter pharmaceutical drugs (medications), vaccines, biopharmaceuticals, blood transfusions, medical devices, electromagnetic radiation emitting devices (ERED), cosmetics, Animal feed, animal foods & feed and Veterinary medicine, veterinary products. The FDA's primary focus is enforcement of the Federal Food, Drug, and Cosmetic Act (FD&C), but the agency also enforces other laws, notably Section 361 of the Public Health Service Act, as well as associated regulations. Much of this regulatory-enforcement work is not d ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Contura International
The Contura was a line of notebook computers produced by Compaq. Released in 1992, the Contura was Compaq's first attempt at making an affordable, entry-level laptop computer. Contura series The main Contura series included models 3/20, 3/25, 3/25c, 4/25, 4/25c, 4/25cx, 400, 400C, 400CX, 410, 410C, 410CX, 420C, 420CX, 430C, and 430CX. These were standard-size notebooks, not ultra-portable subnotebook computers. The "X" designation denoted an active matrix screen. 3/20 * 386SL running at 20 MHz * Display: VGA monochrome * RAM: 2 MB * 40 MB or 84 MB hard disk * External trackball attached to the side of the laptop 3/25c * 386SL running at 25 MHz * Display: VGA color * RAM: 4 MB * 80 MB or 120 MB hard disk * External trackball attached to the side of the laptop 4/25 * 486SL running at 25 MHz * Display: VGA monochrome * RAM: 4 MB * 120 MB or 200 MB hard disk * External trackball attached to the side of the laptop 4/25c * 486SL running at 25 MHz * Display: VGA col ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Plastic Surgery Filler
Plastics are a wide range of synthetic or semi-synthetic materials that use polymers as a main ingredient. Their plasticity makes it possible for plastics to be moulded, extruded or pressed into solid objects of various shapes. This adaptability, plus a wide range of other properties, such as being lightweight, durable, flexible, and inexpensive to produce, has led to its widespread use. Plastics typically are made through human industrial systems. Most modern plastics are derived from fossil fuel-based chemicals like natural gas or petroleum; however, recent industrial methods use variants made from renewable materials, such as corn or cotton derivatives. 9.2 billion tonnes of plastic are estimated to have been made between 1950 and 2017. More than half this plastic has been produced since 2004. In 2020, 400 million tonnes of plastic were produced. If global trends on plastic demand continue, it is estimated that by 2050 annual global plastic production will reach over 1,10 ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Acrylate Polymers
An acrylate polymer (also known as acrylic or polyacrylate) is any of a group of polymers prepared from acrylate monomers. These plastics are noted for their transparency, resistance to breakage, and elasticity. Acrylate polymer is commonly used in cosmetics, such as nail polish, as an adhesive. History The first synthesis of acrylic polymer was reported by G.W.A Kahlbaum in 1880. Acrylic elastomers Acrylic elastomer is a general term for a type of synthetic rubber whose primary component is acrylic acid alkylester (ethyl or butyl ester). Acrylic elastomer possesses characteristics of heat and oil resistance, with the ability to withstand temperatures of 170–180 °C. It is used primarily for producing oil seals and packaging related to automobiles. Acrylic elastomer can generally be characterized as one of two types. "Old" types include ACM (copolymer of acrylic acid ester and 2-chloroethyl vinyl ether) containing chlorine and ANM (copolymer of acrylic acid ester and ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Polyelectrolytes
Polyelectrolytes are polymers whose repeating units bear an electrolyte group. Polycations and polyanions are polyelectrolytes. These groups dissociate in aqueous solutions (water), making the polymers charged. Polyelectrolyte properties are thus similar to both electrolytes ( salts) and polymers (high molecular weight compounds) and are sometimes called polysalts. Like salts, their solutions are electrically conductive. Like polymers, their solutions are often viscous. Charged molecular chains, commonly present in soft matter systems, play a fundamental role in determining structure, stability and the interactions of various molecular assemblies. Theoretical approaches to describing their statistical properties differ profoundly from those of their electrically neutral counterparts, while technological and industrial fields exploit their unique properties. Many biological molecules are polyelectrolytes. For instance, polypeptides, glycosaminoglycans, and DNA are polyelect ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
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