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Aphallia
Aphallia is a congenital malformation in which the phallus (penis or clitoris) is absent. It is also known as penile agenesis in the case of males. The word is derived from the Greek ''a-'' for "not", and ''phallos'' for "penis". It is classified as an intersex variation. Causes Aphallia has no known cause. It is not linked to deficient hormone amounts or action, but rather to a failure of the fetal genital tubercle to form between 3 and 6 weeks after conception. The urethra of an affected child opens on the perineum. Diagnosis Treatment Congenital anomalies like cryptorchidism, renal agenesis/dysplasia, musculoskeletal and cardiopulmonary anomalies are also common (>50% cases), hence evaluation of the patient for internal anomalies is mandatory. Although aphallia can occur in any body type, it is considered a substantially more troublesome problem with those who have testes present, and has in the past sometimes been considered justification for assigning and rearing a genetica ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Congenital Disorder
A birth defect, also known as a congenital disorder, is an abnormal condition that is present at birth regardless of its cause. Birth defects may result in disabilities that may be physical, intellectual, or developmental. The disabilities can range from mild to severe. Birth defects are divided into two main types: structural disorders in which problems are seen with the shape of a body part and functional disorders in which problems exist with how a body part works. Functional disorders include metabolic and degenerative disorders. Some birth defects include both structural and functional disorders. Birth defects may result from genetic or chromosomal disorders, exposure to certain medications or chemicals, or certain infections during pregnancy. Risk factors include folate deficiency, drinking alcohol or smoking during pregnancy, poorly controlled diabetes, and a mother over the age of 35 years old. Many are believed to involve multiple factors. Birth defects may b ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Sex Assignment
Sex assignment (sometimes known as gender assignment) is the discernment of an infant's sex at or before birth. A relative, midwife, nurse or physician inspects the external genitalia when the baby is delivered and, in more than 99.95% of births, sex is assigned without ambiguity. Assignment may also be done prior to birth through prenatal sex discernment. The sex assignment at or before birth usually aligns with a child's anatomical sex and phenotype. The number of births where the baby is intersex—where they do not fit into typical definitions of male and female at birth—has been reported to be as low as 0.018%, but is often estimated at around 0.2%. The number of births with ambiguous genitals is in the range of 0.02% to 0.05%. These conditions may complicate sex assignment. Other intersex conditions involve atypical chromosomes, gonads or hormones. Reinforcing sex assignments through surgical or hormonal interventions is often considered to violate the individual's ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Congenital Disorders Of Genital Organs
A birth defect, also known as a congenital disorder, is an abnormal condition that is present at birth regardless of its cause. Birth defects may result in disabilities that may be physical, intellectual, or developmental. The disabilities can range from mild to severe. Birth defects are divided into two main types: structural disorders in which problems are seen with the shape of a body part and functional disorders in which problems exist with how a body part works. Functional disorders include metabolic and degenerative disorders. Some birth defects include both structural and functional disorders. Birth defects may result from genetic or chromosomal disorders, exposure to certain medications or chemicals, or certain infections during pregnancy. Risk factors include folate deficiency, drinking alcohol or smoking during pregnancy, poorly controlled diabetes, and a mother over the age of 35 years old. Many are believed to involve multiple factors. Birth defects may be ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Anorchia
Anorchia (also called anorchidism or anorchism) is a disorder of sex development in which a person with XY karyotype, which corresponds to male sex, is born without testes. Within a few weeks of fertilization, the embryo develops rudimentary gonads (testes), which produce hormones responsible for the development of the reproductive system. If the testes fail to develop within eight weeks, the baby will develop female genitalia (see Swyer syndrome). If the testes begin to develop but are lost or cease to function between eight and 10 weeks, the baby will have ambiguous genitalia when it is born. However, if the testes are lost after 14 weeks, the baby will have partial male genitalia with the notable absence of gonads. Tests include observable lack of testes, low testosterone levels (typical female levels), elevated follicle stimulating hormone and luteinizing hormone levels, XY karyotype, ultrasound or magnetic resonance imaging showing absent gonadal tissue, low bone density, l ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Perineal Urethra
Hypospadias is a common variation in fetal development of the penis in which the urethra does not open from its usual location in the head of the penis. It is the second-most common birth abnormality of the male reproductive system, affecting about one of every 250 males at birth. Roughly 90% of cases are the less serious distal hypospadias, in which the urethral opening (the meatus) is on or near the head of the penis ( glans). The remainder have proximal hypospadias, in which the meatus is all the way back on the shaft of the penis, near or within the scrotum. Shiny tissue that should have made the urethra extends from the meatus to the tip of the glans; this tissue is called the urethral plate. In most cases, the foreskin is less developed and does not wrap completely around the penis, leaving the underside of the glans uncovered. Also, a downward bending of the penis, commonly referred to as chordee, may occur. Chordee is found in 10% of distal hypospadias and 50% of proximal ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Phalloplasty
Phalloplasty is the construction or reconstruction of a penis or the artificial modification of the penis by surgery. The term is also occasionally used to refer to penis enlargement. History Russian surgeon Nikolaj Bogoraz performed the first reconstruction of a total penis using rib cartilage in a reconstructed phallus made from a tubed abdominal flap in 1936. The first female to male sex reassignment surgery was performed in 1946 by Sir Harold Gillies on fellow physician Michael Dillon, a trans man, documented in Pagan Kennedy's book ''The First Man-Made Man''. Gillies' technique remained the standard one for decades. Later improvements in microsurgery made more techniques available. Indications A complete construction or reconstruction of a penis can be performed on patients who: * Have congenital anomalies such as micropenis, epispadias, and hypospadias * Have lost their penis * Desire sex reassignment surgery as part of their gender transition. Techniques and relate ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Intersex Society Of North America
The Intersex Society of North America (ISNA) was a non-profit advocacy group founded in 1993 by Cheryl Chase to end shame, secrecy, and unwanted genital surgeries.Matthews, Karen (Oct 22, 2000). Debate Grows Over Using Surgery on Infants with Ambiguous Genitals. ''Los Angeles Times''Murrell, Nancy (October 28, 1998). Intersex group raises questions about genital surgery. ''Miami Herald''Hackford-Peer, Kim (2005). Cheryl Chase Founds the Intersex Society of North America. in ''GLBT History, 1993–2004''; 2005, p28-30, 2p Other notable members included Morgan Holmes, Max Beck, Howard (Tiger) Devore, Esther Morris Leidolf and Alice Dreger. The organization closed in June 2008,Staff report (June 28, 2008)Farewell message. via ISNA.org and has been succeeded by a number of health, civil and human rights organizations including interACT. Advocacy Physical integrity and bodily autonomy ISNA stated that newborn intersex genitals should not be operated on, unless they need to be in ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Social Construct
Social constructionism is a theory in sociology, social ontology, and communication theory which proposes that certain ideas about physical reality arise from collaborative consensus, instead of pure observation of said reality. The theory centers on the notion that meanings are developed in coordination with others rather than separately by each individual. It has often been characterised as neo- Marxian or also as a neo- Kantian theory, in that social constructionism replaces the transcendental subject with a concept of society that is at the same time descriptive and normative. While some social constructs are obvious, for instance money or the concept of currency, in that people have agreed to give it importance/value, others are controversial and hotly debated, such as the concept of self/self-identity. This articulates the view that people in society construct ideas or concepts that may not exist without the existence of people or language to validate those concepts ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Genetics
Genetics is the study of genes, genetic variation, and heredity in organisms.Hartl D, Jones E (2005) It is an important branch in biology because heredity is vital to organisms' evolution. Gregor Mendel, a Moravian Augustinian friar working in the 19th century in Brno, was the first to study genetics scientifically. Mendel studied "trait inheritance", patterns in the way traits are handed down from parents to offspring over time. He observed that organisms (pea plants) inherit traits by way of discrete "units of inheritance". This term, still used today, is a somewhat ambiguous definition of what is referred to as a gene. Trait inheritance and molecular inheritance mechanisms of genes are still primary principles of genetics in the 21st century, but modern genetics has expanded to study the function and behavior of genes. Gene structure and function, variation, and distribution are studied within the context of the cell, the organism (e.g. dominance), and within the ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Sex Of Rearing
Sex assignment (sometimes known as gender assignment) is the discernment of an infant's sex at or before birth. A relative, midwife, nurse or physician inspects the external genitalia when the baby is delivered and, in more than 99.95% of births, sex is assigned without ambiguity. Assignment may also be done prior to birth through prenatal sex discernment. The sex assignment at or before birth usually aligns with a child's anatomical sex and phenotype. The number of births where the baby is intersex—where they do not fit into typical definitions of male and female at birth—has been reported to be as low as 0.018%, but is often estimated at around 0.2%. The number of births with ambiguous genitals is in the range of 0.02% to 0.05%. These conditions may complicate sex assignment. Other intersex conditions involve atypical chromosomes, gonads or hormones. Reinforcing sex assignments through surgical or hormonal interventions is often considered to violate the individual's hum ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Cryptorchidism
Cryptorchidism, also known as undescended testis, is the failure of one or both testes to descend into the scrotum. The word is from Greek () 'hidden' and () 'testicle'. It is the most common birth defect of the male genital tract. About 3% of full-term and 30% of premature infant boys are born with at least one undescended testis. However, about 80% of cryptorchid testes descend by the first year of life (the majority within three months), making the true incidence of cryptorchidism around 1% overall. Cryptorchidism may develop after infancy, sometimes as late as young adulthood, but that is exceptional. Cryptorchidism is distinct from monorchism, the condition of having only one testicle. Though the condition may occur on one or both sides, it more commonly affects the right testis. A testis absent from the normal scrotal position may be: # Anywhere along the "path of descent" from high in the posterior (retroperitoneal) abdomen, just below the kidney, to the inguinal ring ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Phallus (embryology)
In embryology, the primordial phallus refers to the clitoris of a female or the penis in the male, particularly during fetal development of the urinary and reproductive organs, before sexual differentiation is evident. This is also the case for the immature male analog, the immature glans penis. Image:Primordial_phallus,_low_mag.jpg, Micrograph of the primordial phallus, H&E stain. Image:Primordial_phallus,_intermed._mag.1.jpg, Micrograph of the primordial phallus, H&E stain. See also * Aphallia * Genital tubercle A genital tubercle or phallic tubercle is a body of tissue present in the development of the reproductive system. It forms in the ventral, caudal region of mammalian embryos of both sexes, and eventually develops into a primordial phallus. In t ... Embryology of urogenital system {{developmental-biology-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
