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Antimicrobial Stewardship
Antimicrobial stewardship is the systematic effort to educate and persuade prescribers of antimicrobials to follow evidence-based prescribing, in order to stem antimicrobial overuse, and thus antimicrobial resistance. AMS has been an organized effort of specialists in infectious diseases, both in Internal Medicine and Pediatrics with their respective peer-organizations, hospital pharmacists, the public health community and their professional organizations since the late 1990s. It has first been implemented in hospitals. In the U.S., within the context of physicians' prescribing freedom (choice of prescription drugs), AMS had largely been voluntary self-regulation in the form of policies and appeals to adhere to a prescribing self-discipline until 2017, when the Joint Commission prescribed that hospitals should have an Antimicrobial Stewardship team, which was expanded to the outpatient setting in 2020. As of 2019, California and Missouri had made AMS programs mandatory by law. ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Antimicrobial
An antimicrobial is an agent that kills microorganisms or stops their growth. Antimicrobial medicines can be grouped according to the microorganisms they act primarily against. For example, antibiotics are used against bacteria, and antifungals are used against fungi. They can also be classified according to their function. Agents that kill microbes are microbicides, while those that merely inhibit their growth are called bacteriostatic agents. The use of antimicrobial medicines to treat infection is known as antimicrobial chemotherapy, while the use of antimicrobial medicines to prevent infection is known as antimicrobial prophylaxis. The main classes of antimicrobial agents are disinfectants (non-selective agents, such as bleach), which kill a wide range of microbes on non-living surfaces to prevent the spread of illness, antiseptics (which are applied to living tissue and help reduce infection during surgery), and antibiotics (which destroy microorganisms within the body). The ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Invasive Candidiasis
Invasive candidiasis is an infection (candidiasis) that can be caused by various species of ''Candida'' yeast. Unlike ''Candida'' infections of the mouth and throat (oral candidiasis) or vagina ( ''Candidal'' vulvovaginitis), invasive candidiasis is a serious, progressive, and potentially fatal infection that can affect the blood ( fungemia), heart, brain, eyes, bones, and other parts of the body. Signs and symptoms Symptoms of invasive candidiasis can be confused with other medical conditions, however, the most common symptoms are fever and chills that do not improve with antibiotic treatment. Other symptoms develop as the infection spreads, depending on which parts of the body are involved. Presentation Invasive candidiasis can manifest as serious diseases including as fungemia, endocarditis, endophthalmitis, osteomyelitis, and central nervous system infections. Cause Invasive candidiasis is caused by 15 of the more than 150 known species of ''Candida''. These species ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Clinical Pharmacy
230px, A hospital pharmacist is checking a liquid solution. Clinical pharmacy is the branch of pharmacy in which clinical pharmacists provide direct patient care that optimizes the use of medication and promotes health, wellness, and disease prevention. Clinical pharmacists care for patients in all health care settings but the clinical pharmacy movement initially began inside hospitals and clinics. Clinical pharmacists often work in collaboration with physicians, physician assistants, nurse practitioners, and other healthcare professionals. Clinical pharmacists can enter into a formal collaborative practice agreement with another healthcare provider, generally one or more physicians, that allows pharmacists to prescribe medications and order laboratory tests. Education and credentialing Clinical pharmacists have extensive education in the biomedical, pharmaceutical, socio-behavioural and clinical sciences. Most clinical pharmacists have a Doctor of Pharmacy (Pharm.D.) degr ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Punched Card
A punched card (also punch card or punched-card) is a piece of stiff paper that holds digital data represented by the presence or absence of holes in predefined positions. Punched cards were once common in data processing applications or to directly control automated machinery. Punched cards were widely used through much of the 20th century in the data processing industry, where specialized and increasingly complex unit record equipment, unit record machines, organized into semiautomatic data processing systems, used punched cards for data input, output, and storage. The IBM 12-row/80-column punched card format came to dominate the industry. Many early digital computers used punched cards as the primary medium for input of both computer programs and Data (computing), data. While punched cards are now obsolete as a storage medium, as of 2012, some voting machines still used punched cards to record votes. They also had a significant cultural impact. History The idea of contr ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Winnipeg
Winnipeg () is the capital and largest city of the province of Manitoba in Canada. It is centred on the confluence of the Red and Assiniboine rivers, near the longitudinal centre of North America. , Winnipeg had a city population of 749,607 and a metropolitan population of 834,678, making it the sixth-largest city, and eighth-largest metropolitan area in Canada. The city is named after the nearby Lake Winnipeg; the name comes from the Western Cree words for "muddy water" - “winipīhk”. The region was a trading centre for Indigenous peoples long before the arrival of Europeans; it is the traditional territory of the Anishinabe (Ojibway), Ininew (Cree), Oji-Cree, Dene, and Dakota, and is the birthplace of the Métis Nation. French traders built the first fort on the site in 1738. A settlement was later founded by the Selkirk settlers of the Red River Colony in 1812, the nucleus of which was incorporated as the City of Winnipeg in 1873. Being far inland, the local cl ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Alexander Fleming
Sir Alexander Fleming (6 August 1881 – 11 March 1955) was a Scottish physician and microbiologist, best known for discovering the world's first broadly effective antibiotic substance, which he named penicillin. His discovery in 1928 of what was later named benzylpenicillin (or penicillin G) from the mould ''Penicillium rubens'' is described as the "single greatest victory ever achieved over disease." For this discovery, he shared the Nobel Prize in Physiology or Medicine in 1945 with Howard Florey and Ernst Boris Chain. He also discovered the enzyme lysozyme from his nasal discharge in 1922, and along with it a bacterium he named ''Micrococcus Lysodeikticus'', later renamed ''Micrococcus luteus''. Fleming was knighted for his scientific achievements in 1944. In 1999, he was named in ''Time'' magazine's list of the 100 Most Important People of the 20th century. In 2002, he was chosen in the BBC's television poll for determining the 100 Greatest Britons, and in 2009, h ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Wastewater
Wastewater is water generated after the use of freshwater, raw water, drinking water or saline water in a variety of deliberate applications or processes. Another definition of wastewater is "Used water from any combination of domestic, industrial, commercial or agricultural activities, surface runoff / storm water, and any sewer inflow or sewer infiltration". In everyday usage, wastewater is commonly a synonym for sewage (also called sewerage, domestic wastewater, or municipal wastewater), which is wastewater that is produced by a community of people. As a generic term wastewater may also be used to describe water containing contaminants accumulated in other settings, such as: * Industrial wastewater: waterborne waste generated from a variety of industrial processes, such as manufacturing operations, mineral extraction, power generation, or water and wastewater treatment. ** Cooling water, released with potential thermal pollution after use to condense steam or reduce machi ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Water Cycle
The water cycle, also known as the hydrologic cycle or the hydrological cycle, is a biogeochemical cycle that describes the continuous movement of water on, above and below the surface of the Earth. The mass of water on Earth remains fairly constant over time but the partitioning of the water into the major reservoirs of ice, fresh water, saline water (salt water) and atmospheric water is variable depending on a wide range of climatic variables. The water moves from one reservoir to another, such as from river to ocean, or from the ocean to the atmosphere, by the physical processes of evaporation, transpiration, condensation, precipitation, infiltration, surface runoff, and subsurface flow. In doing so, the water goes through different forms: liquid, solid (ice) and vapor. The ocean plays a key role in the water cycle as it is the source of 86% of global evaporation. The water cycle involves the exchange of energy, which leads to temperature changes. When water evaporates, ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Microbiota
Microbiota are the range of microorganisms that may be commensal, symbiotic, or pathogenic found in and on all multicellular organisms, including plants. Microbiota include bacteria, archaea, protists, fungi, and viruses, and have been found to be crucial for immunologic, hormonal, and metabolic homeostasis of their host. The term ''microbiome'' describes either the collective genomes of the microbes that reside in an ecological niche or within the microbes themselves. The microbiome and host emerged during evolution as a synergistic unit from epigenetics and genetic characteristics, sometimes collectively referred to as a holobiont. The presence of microbiota in human and other metazoan guts has been critical for understanding the co-evolution between metazoans and bacteria. Microbiota play key roles in the intestinal immune and metabolic responses via their fermentation product (short-chain fatty acid), acetate. Introduction All plants and animals, from simple life fo ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Biota (ecology)
A biome () is a biogeographical unit consisting of a biological community that has formed in response to the physical environment in which they are found and a shared regional climate. Biomes may span more than one continent. Biome is a broader term than habitat and can comprise a variety of habitats. While a biome can cover large areas, a microbiome is a mix of organisms that coexist in a defined space on a much smaller scale. For example, the human microbiome is the collection of bacteria, viruses, and other microorganisms that are present on or in a human body. A biota is the total collection of organisms of a geographic region or a time period, from local geographic scales and instantaneous temporal scales all the way up to whole-planet and whole-timescale spatiotemporal scales. The biotas of the Earth make up the biosphere. Etymology The term was suggested in 1916 by Clements, originally as a synonym for '' biotic community'' of Möbius (1877). Later, it gained its c ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Environmental Degradation
Environmental degradation is the deterioration of the environment (biophysical), environment through depletion of resources such as quality of air, water and soil; the destruction of ecosystems; habitat destruction; the extinction of wildlife; and pollution. It is defined as any change or disturbance to the environment perceived to be deleterious or undesirable. Environmental concerns can be defined as the negative effects of any human activity on the environment. The biological as well as the physical features of the environment are included. Some of the primary environmental challenges that are causing great worry are air pollution, water pollution, natural environment pollution, rubbish pollution, and so o Environmental degradation is one of the ten threats officially cautioned by the High-level Panel on Threats, Challenges and Change, high-level PaneI on Threats, Challenges and Change of the United Nations. The United Nations International Strategy for Disaster Reduction defin ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Skin Flora
Skin flora, also called skin microbiota, refers to microbiota (communities of microorganisms) that reside on the skin, typically human skin. Many of them are bacteria of which there are around 1,000 species upon human skin from nineteen phyla.Pappas S. (2009)Your Body Is a Wonderland ... of Bacteria ScienceNOW Daily News Most are found in the superficial layers of the epidermis and the upper parts of hair follicles. Skin flora is usually non-pathogenic, and either commensal (are not harmful to their host) or mutualistic (offer a benefit). The benefits bacteria can offer include preventing transient pathogenic organisms from colonizing the skin surface, either by competing for nutrients, secreting chemicals against them, or stimulating the skin's immune system. However, resident microbes can cause skin diseases and enter the blood system, creating life-threatening diseases, particularly in immunosuppressed people. A major non-human skin flora is ''Batrachochytrium dendrobatid ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
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