Anthrax Weaponization
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Anthrax Weaponization
Anthrax weaponization is the development and deployment of the bacterium '' Bacillus anthracis'' or, more commonly, its spore (referred to as anthrax), as a biological weapon. As a biological weapon, anthrax has been used in biowarfare and bioterrorism since 1914. However, in 1975 the Biological Weapons Convention prohibited the "development, production and stockpiling" of biological weapons. It has since been used in bioterrorism. Anthrax spores can cause infection from inhalation, skin contact, ingestion or injection and when untreated can lead to death. Likely delivery methods of weaponized anthrax include aerial dispersal or dispersal through livestock, notable bioterrorism uses include the 2001 anthrax attacks and an incident in 1993 by the Aum Shinrikyo group in Japan. Biological overview Concentrated anthrax spores, and not necessarily the bacterium '' Bacillus anthracis'', pose the biggest risk as a biological weapons to humans. When airborne, anthrax spores are not e ...
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Bacillus Anthracis
''Bacillus anthracis'' is a gram-positive and rod-shaped bacterium that causes anthrax, a deadly disease to livestock and, occasionally, to humans. It is the only permanent ( obligate) pathogen within the genus ''Bacillus''. Its infection is a type of zoonosis, as it is transmitted from animals to humans. It was discovered by a German physician Robert Koch in 1876, and became the first bacterium to be experimentally shown as a pathogen. The discovery was also the first scientific evidence for the germ theory of diseases. ''B. anthracis'' measures about 3 to 5 μm long and 1 to 1.2 μm wide. The reference genome consists of a 5,227,419 bp circular chromosome and two extrachromosomal DNA plasmids, pXO1 and pXO2, of 181,677 and 94,830 bp respectively, which are responsible for the pathogenicity. It forms a protective layer called endospore by which it can remain inactive for many years and suddenly becomes infective under suitable environmental conditions. Because of the resilie ...
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Hart Senate Office Building
The Philip A. Hart Senate Office Building is the third U.S. Senate office building, and is located on 2nd Street NE between Constitution Avenue NE and C Street NE in Washington, D.C., in the United States. Construction began in January 1975, and it was first occupied in November 1982. Rapidly rising construction costs plagued the building, creating several scandals. The structure is named for Philip Hart, who served 18 years as a senator from Michigan. Accessed via a spur of the United States Capitol Subway System, the building features a nine-story atrium dominated by massive artwork, and a large Central Hearing Facility which provides television facilities as well as extensive seating. Design and construction The Dirksen Senate Office Building was intended to occupy the entire block bounded by 1st Street NE, Constitution Avenue NE, 2nd Street NE, and C Street NE. However, due to the resource and financial demands of the Korean War, the building was scaled back and occupied on ...
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Chloramphenicol
Chloramphenicol is an antibiotic useful for the treatment of a number of bacterial infections. This includes use as an eye ointment to treat conjunctivitis. By mouth or by injection into a vein, it is used to treat meningitis, plague, cholera, and typhoid fever. Its use by mouth or by injection is only recommended when safer antibiotics cannot be used. Monitoring both blood levels of the medication and blood cell levels every two days is recommended during treatment. Common side effects include bone marrow suppression, nausea, and diarrhea. The bone marrow suppression may result in death. To reduce the risk of side effects treatment duration should be as short as possible. People with liver or kidney problems may need lower doses. In young children a condition known as gray baby syndrome may occur which results in a swollen stomach and low blood pressure. Its use near the end of pregnancy and during breastfeeding is typically not recommended. Chloramphenicol is a broad-spectrum ...
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