Anne Warner (scientist)
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Anne Warner (scientist)
Anne E. Warner (25 August 1940 – 16 May 2012) was a British biologist and a professor in the Department of Cell and Developmental Biology at University College London. Her major field of research was morphogenesis. Warner was known for her work and leadership in a variety of research projects and organisations. She is perhaps most well known for her roles as a cell electrophysiologist, politician of science, and founder of the organisation UCL centre CoMPLEX. Education Born Anne Elizabeth Brookes on 25 August 1940 at Golders Green, she was the only child of Elizabeth (''née'' Marshall) and James Frederick Crompton Brooks (1914–1996), an engineer in the Ministry of Aircraft Production. She was educated at Pate's Grammar School for Girls in Cheltenham, going on to study at University College London where she graduated with a BSc in physiology. She studied for her PhD at the National Institute for Medical Research under the supervision of Otto Hutter, receiving her docto ...
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Electrophysiology
Electrophysiology (from Greek , ''ēlektron'', "amber" etymology of "electron"">Electron#Etymology">etymology of "electron" , ''physis'', "nature, origin"; and , '' -logia'') is the branch of physiology that studies the electrical properties of biological cells and tissues. It involves measurements of voltage changes or electric current or manipulations on a wide variety of scales from single ion channel proteins to whole organs like the heart. In neuroscience, it includes measurements of the electrical activity of neurons, and, in particular, action potential activity. Recordings of large-scale electric signals from the nervous system, such as electroencephalography, may also be referred to as electrophysiological recordings. They are useful for electrodiagnosis and monitoring. Definition and scope Classical electrophysiological techniques Principle and mechanisms Electrophysiology is the branch of physiology that pertains broadly to the flow of ions (ion current) in biologi ...
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Embryological Development
Prenatal development () includes the development of the embryo and of the fetus during a viviparous animal's gestation. Prenatal development starts with fertilization, in the germinal stage of embryonic development, and continues in fetal development until birth. In human pregnancy, prenatal development is also called antenatal development. The development of the human embryo follows fertilization, and continues as fetal development. By the end of the tenth week of gestational age the embryo has acquired its basic form and is referred to as a fetus. The next period is that of fetal development where many organs become fully developed. This fetal period is described both topically (by organ) and chronologically (by time) with major occurrences being listed by gestational age. The very early stages of embryonic development are the same in all mammals, but later stages of development, and the length of gestation varies. Terminology In the human: Different terms are used ...
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CoMPLEX
Complex commonly refers to: * Complexity, the behaviour of a system whose components interact in multiple ways so possible interactions are difficult to describe ** Complex system, a system composed of many components which may interact with each other * Complex (psychology), a core pattern of emotions etc. in the personal unconscious organized around a common theme such as power or status Complex may also refer to: Arts, entertainment and media * Complex (English band), formed in 1968, and their 1971 album ''Complex'' * Complex (band), a Japanese rock band * ''Complex'' (album), by Montaigne, 2019, and its title track * ''Complex'' (EP), by Rifle Sport, 1985 * "Complex" (song), by Gary Numan, 1979 * Complex Networks, publisher of magazine ''Complex'', now online Biology * Protein–ligand complex, a complex of a protein bound with a ligand * Exosome complex, a multi-protein intracellular complex * Protein complex, a group of two or more associated polypeptide chains * Specie ...
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Marine Biological Association
The Marine Biological Association of the United Kingdom (MBA) is a learned society with a scientific laboratory that undertakes research in marine biology. The organisation was founded in 1884 and has been based in Plymouth since the Citadel Hill Laboratory was opened on 30 June 1888. The MBA is also home to the National Marine Biological Library, whose collections cover the marine biological sciences, and curates the Historical Collections. Throughout its history, the MBA has had a royal patron. In 2013, the MBA was granted a royal charter in recognition of the MBA's scientific preeminence in its field. Origins and foundation In 1866 the Royal Commission on the Sea Fisheries, which included among its officers Professor Thomas Henry Huxley, had reported that fears of over-exploitation of the sea fisheries were unfounded. They recommended removing existing laws regulating fishing grounds and closed seasons. However, the increase in the size and number of fishing vessels was ...
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Fellow Of The Royal Society
Fellowship of the Royal Society (FRS, ForMemRS and HonFRS) is an award granted by the judges of the Royal Society of London to individuals who have made a "substantial contribution to the improvement of natural science, natural knowledge, including mathematics, engineering science, and medical science". Fellow, Fellowship of the Society, the oldest known scientific academy in continuous existence, is a significant honour. It has been awarded to many eminent scientists throughout history, including Isaac Newton (1672), Michael Faraday (1824), Charles Darwin (1839), Ernest Rutherford (1903), Srinivasa Ramanujan (1918), Albert Einstein (1921), Paul Dirac (1930), Winston Churchill (1941), Subrahmanyan Chandrasekhar (1944), Dorothy Hodgkin (1947), Alan Turing (1951), Lise Meitner (1955) and Francis Crick (1959). More recently, fellowship has been awarded to Stephen Hawking (1974), David Attenborough (1983), Tim Hunt (1991), Elizabeth Blackburn (1992), Tim Berners-Lee (2001), Venki R ...
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Royal Free Hospital
The Royal Free Hospital (also known simply as the Royal Free) is a major teaching hospital in the Hampstead area of the London Borough of Camden. The hospital is part of the Royal Free London NHS Foundation Trust, which also runs services at Barnet Hospital, Chase Farm Hospital and a number of other sites. The trust is a founder member of the UCLPartners academic health science centre. History Early history What became the Royal Free Hospital was founded in 1828 by the surgeon William Marsden to provide free care to those of little means. It is said that one evening, Marsden found a young girl lying on the steps of St. Andrew Church, Holborn, dying from disease and hunger and sought help for her from one of the nearby hospitals. However, none would take the girl in and she died two days later. After this experience Marsden set up a small dispensary at 16 Greville Street, Holborn, called the London General Institution for the Gratuitous Care of Malignant Diseases. The hospita ...
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Medical Research Council (United Kingdom)
The Medical Research Council (MRC) is responsible for co-coordinating and funding medical research in the United Kingdom. It is part of United Kingdom Research and Innovation (UKRI), which came into operation 1 April 2018, and brings together the UK's seven research councils, Innovate UK and Research England. UK Research and Innovation is answerable to, although politically independent from, the Department for Business, Energy and Industrial Strategy. The MRC focuses on high-impact research and has provided the financial support and scientific expertise behind a number of medical breakthroughs, including the development of penicillin and the discovery of the structure of DNA. Research funded by the MRC has produced 32 Nobel Prize winners to date. History The MRC was founded as the Medical Research Committee and Advisory Council in 1913, with its prime role being the distribution of medical research funds under the terms of the National Insurance Act 1911. This was a consequen ...
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The Physiological Society
The Physiological Society, founded in 1876, is a learned society for physiologists Physiology (; ) is the scientific study of functions and mechanisms in a living system. As a sub-discipline of biology, physiology focuses on how organisms, organ systems, individual organs, cells, and biomolecules carry out the chemical ... in the United Kingdom. History The Physiological Society was founded in 1876 as a dining society "for mutual benefit and protection" by a group of 19 physiologists, led by John Burdon Sanderson and Michael Foster (physiologist), Michael Foster, as a result of the 1875 Royal Commission on Vivisection and the subsequent 1876 Cruelty to Animals Act. Other founding members included: William Sharpey, Thomas Henry Huxley, Thomas Huxley, George Henry Lewes, Francis Galton, John Marshall (surgeon), John Marshall, George Murray Humphry, Frederick William Pavy, Lauder Brunton, David Ferrier, Philip Pye-Smith, W. H. Gaskell, Walter H. Gaskell, John Gray McKend ...
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Roslin Institute
The Roslin Institute is an animal sciences research institute at Easter Bush, Midlothian, Scotland, part of the University of Edinburgh, and is funded by the Biotechnology and Biological Sciences Research Council. It is best known for creating Dolly the sheep, the first mammal to be successfully cloned from an adult cell. History Institute of Animal Genetics (1917–1980) The Roslin Institute has its roots in the University of Edinburgh's Institute of Animal Genetics (IAG), which was founded in 1917 under the direction of Francis Albert Eley Crew. Poultry Research Centre (1947–1986) The Poultry Research Centre (PRC) was founded in 1947 by the Agricultural Research Council (ARC). The new institute used expertise and material from the IAG, and its laboratories were located adjacent to the IAG's building on the university's King's Buildings campus. A second site housing larger experiments was located on the Bush Estate, south of Edinburgh. In 1971, the institute's experim ...
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Lister Institute Of Preventive Medicine
The Lister Institute of Preventive Medicine, informally known as the Lister Institute, was established as a research institute (the British Institute of Preventive Medicine) in 1891, with bacteriologist Marc Armand Ruffer as its first director, using a grant of £250,000 from Edward Cecil Guinness of the Guinness family. It had premises in Chelsea in London, Sudbury in Suffolk, and Elstree in Hertfordshire, England. It was the first medical research charity in the United Kingdom. It was renamed the Jenner Institute (after Edward Jenner, the pioneer of smallpox vaccine) in 1898 and then, in 1903, as the Lister Institute in honour of the great surgeon and medical pioneer, Dr Joseph Lister. In 1905, the institute became a school of the University of London. History Until the 1970s the institute maintained laboratories and conducted research on infectious disease and vaccines. It was funded by manufacturing and selling vaccines. In the 1970s the institute ran into financial diffi ...
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Marine Biological Association Of The United Kingdom
The Marine Biological Association of the United Kingdom (MBA) is a learned society with a scientific laboratory that undertakes research in marine biology. The organisation was founded in 1884 and has been based in Plymouth since the Citadel Hill Laboratory was opened on 30 June 1888. The MBA is also home to the National Marine Biological Library, whose collections cover the marine biological sciences, and curates the Historical Collections. Throughout its history, the MBA has had a royal patron. In 2013, the MBA was granted a royal charter in recognition of the MBA's scientific preeminence in its field. Origins and foundation In 1866 the Royal Commission on the Sea Fisheries, which included among its officers Professor Thomas Henry Huxley, had reported that fears of over-exploitation of the sea fisheries were unfounded. They recommended removing existing laws regulating fishing grounds and closed seasons. However, the increase in the size and number of fishing vessels was ca ...
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Antibody
An antibody (Ab), also known as an immunoglobulin (Ig), is a large, Y-shaped protein used by the immune system to identify and neutralize foreign objects such as pathogenic bacteria and viruses. The antibody recognizes a unique molecule of the pathogen, called an antigen. Each tip of the "Y" of an antibody contains a paratope (analogous to a lock) that is specific for one particular epitope (analogous to a key) on an antigen, allowing these two structures to bind together with precision. Using this binding mechanism, an antibody can ''tag'' a microbe or an infected cell for attack by other parts of the immune system, or can neutralize it directly (for example, by blocking a part of a virus that is essential for its invasion). To allow the immune system to recognize millions of different antigens, the antigen-binding sites at both tips of the antibody come in an equally wide variety. In contrast, the remainder of the antibody is relatively constant. It only occurs in a few varia ...
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