Anne McLaren
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Anne McLaren
Dame Anne Laura Dorinthea McLaren, (26 April 1927 – 7 July 2007) was a British scientist who was a leading figure in developmental biology. Her work helped lead to human in vitro fertilisation (IVF),''The Telegraph'' obituary for Prof. Dame Anne McLaren
9 July 2007
and she received many honours for her contributions to science, including election as fellow of the .


Early life

McLaren was the daughter of Sir

The Honourable
''The Honourable'' (British English) or ''The Honorable'' (American English; see spelling differences) (abbreviation: ''Hon.'', ''Hon'ble'', or variations) is an honorific style that is used as a prefix before the names or titles of certain people, usually with official governmental or diplomatic positions. Use by governments International diplomacy In international diplomatic relations, representatives of foreign states are often styled as ''The Honourable''. Deputy chiefs of mission, , consuls-general and consuls are always given the style. All heads of consular posts, whether they are honorary or career postholders, are accorded the style according to the State Department of the United States. However, the style ''Excellency'' instead of ''The Honourable'' is used for ambassadors and high commissioners. Africa The Congo In the Democratic Republic of the Congo, the prefix 'Honourable' or 'Hon.' is used for members of both chambers of the Parliament of the Democratic Repu ...
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Zoology
Zoology ()The pronunciation of zoology as is usually regarded as nonstandard, though it is not uncommon. is the branch of biology that studies the Animal, animal kingdom, including the anatomy, structure, embryology, evolution, Biological classification, classification, Ethology, habits, and distribution of all animals, both living and extinction, extinct, and how they interact with their ecosystems. The term is derived from Ancient Greek , ('animal'), and , ('knowledge', 'study'). Although humans have always been interested in the natural history of the animals they saw around them, and made use of this knowledge to domesticate certain species, the formal study of zoology can be said to have originated with Aristotle. He viewed animals as living organisms, studied their structure and development, and considered their adaptations to their surroundings and the function of their parts. The Greek physician Galen studied human anatomy and was one of the greatest surgeons of the a ...
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Jonathan Michie
Jonathan Michie (born 25 March 1957, London, England) is a British economist who is president of Kellogg College, Oxford, where he is professor of innovation and knowledge exchange. Early life Michie is the son of the biologist Dame Anne McLaren and computer scientist Donald Michie, and brother of the academic psychologist Susan Michie. Academic career Michie studied at United World College of the Atlantic from 1973 where he gained his International Baccalaureate. He then gained a scholarship to Balliol College, Oxford, where he gained first class honours in Philosophy, Politics and Economics, and later a doctorate, after having obtained an MSc in Economics (with Distinction) from Queen Mary, University of London. In 1983 he moved to the Economics Department of the Trades Union Congress and then in 1988 to Brussels as an Expert to the European Commission, before becoming an academic at the University of Cambridge in 1990. After seven years at Cambridge – first in the Economics ...
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Susan Fiona Dorinthea Michie
Susan Fiona Dorinthea Michie (born 19 June 1955) is a British academic, clinical psychologist, and professor of health psychology, director of The Centre for Behaviour Change and head of The Health Psychology Research Group, all at University College London. She is also an advisor to the British Government via the SAGE advisory group on matters concerning behavioural compliance with government regulations during the COVID-19 pandemic. In 2022, she was appointed Chair of the World Health Organisation’s (WHO) Technical Advisory Group on Behavioural Insights and Sciences for Health. Early life Born in St Pancras, London, Michie is the daughter of the biologist Dame Anne McLaren and computer scientist Donald Michie, and sister of the economist Jonathan Michie. Michie obtained a BA in experimental psychology from University College, Oxford in 1976, an MPhil in clinical psychology from the Institute of Psychiatry in 1978, and a DPhil in developmental psychology from University Co ...
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Blastocyst
The blastocyst is a structure formed in the early embryonic development of mammals. It possesses an inner cell mass (ICM) also known as the ''embryoblast'' which subsequently forms the embryo, and an outer layer of trophoblast cells called the trophectoderm. This layer surrounds the inner cell mass and a fluid-filled cavity known as the blastocoel. In the late blastocyst the trophectoderm is known as the trophoblast. The trophoblast gives rise to the chorion and amnion, the two fetal membranes that surround the embryo. The placenta derives from the embryonic chorion (the portion of the chorion that develops villi) and the underlying uterine tissue of the mother. The name "blastocyst" arises from the Greek ' ("a sprout") and ' ("bladder, capsule"). In other animals this is a structure consisting of an undifferentiated ball of cells and is called a blastula. In humans, blastocyst formation begins about five days after fertilization when a fluid-filled cavity opens up in the mor ...
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John D
John is a common English name and surname: * John (given name) * John (surname) John may also refer to: New Testament Works * Gospel of John, a title often shortened to John * First Epistle of John, often shortened to 1 John * Second Epistle of John, often shortened to 2 John * Third Epistle of John, often shortened to 3 John People * John the Baptist (died c. AD 30), regarded as a prophet and the forerunner of Jesus Christ * John the Apostle (lived c. AD 30), one of the twelve apostles of Jesus * John the Evangelist, assigned author of the Fourth Gospel, once identified with the Apostle * John of Patmos, also known as John the Divine or John the Revelator, the author of the Book of Revelation, once identified with the Apostle * John the Presbyter, a figure either identified with or distinguished from the Apostle, the Evangelist and John of Patmos Other people with the given name Religious figures * John, father of Andrew the Apostle and Saint Peter * Pope Jo ...
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Nature (journal)
''Nature'' is a British weekly scientific journal founded and based in London, England. As a multidisciplinary publication, ''Nature'' features peer-reviewed research from a variety of academic disciplines, mainly in science and technology. It has core editorial offices across the United States, continental Europe, and Asia under the international scientific publishing company Springer Nature. ''Nature'' was one of the world's most cited scientific journals by the Science Edition of the 2019 ''Journal Citation Reports'' (with an ascribed impact factor of 42.778), making it one of the world's most-read and most prestigious academic journals. , it claimed an online readership of about three million unique readers per month. Founded in autumn 1869, ''Nature'' was first circulated by Norman Lockyer and Alexander Macmillan as a public forum for scientific innovations. The mid-20th century facilitated an editorial expansion for the journal; ''Nature'' redoubled its efforts in exp ...
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Superpregnancy
Superfetation (also spelled superfoetation – see fetus) is the simultaneous occurrence of more than one stage of developing offspring in the same animal. In mammals, it manifests as the formation of an embryo from a different menstrual cycle while another embryo or fetus is already present in the uterus. When two separate instances of fertilisation occur during the same menstrual cycle, it is known as superfecundation. Humans While proposed cases of superfetation have been reported in humans, the existence of this phenomenon in humans has been deemed unlikely. Better explanations include differential growth between twins due to various reasons such as twin-to-twin transfusion syndrome. Artificially induced superfetation has been demonstrated, although only up to a short period after insemination. A 2008 French study found evidence to suggest that superfetation is a reality for humans, but that it is so rare that there have been fewer than 10 recorded cases in the world. In 201 ...
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Controlled Ovarian Hyperstimulation
Controlled ovarian hyperstimulation is a technique used in assisted reproduction involving the use of fertility medications to induce ovulation by multiple ovarian follicles. These multiple follicles can be taken out by oocyte retrieval (egg collection) for use in ''in vitro'' fertilisation (IVF), or be given time to ovulate, resulting in superovulation which is the ovulation of a larger-than-normal number of eggs, generally in the sense of at least two. When ovulated follicles are fertilised ''in vivo'', whether by natural or artificial insemination, there is a very high risk of a multiple pregnancy. In this article, unless otherwise specified, hyperstimulation will refer to hyperstimulation as part of IVF. In contrast, ovulation induction is ovarian stimulation without subsequent IVF, with the aim of developing one or two ovulatory follicles (the maximum number before recommending sexual abstinence with such treatment). Procedure Response prediction Response predictors determine ...
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Lumbar Vertebrae
The lumbar vertebrae are, in human anatomy, the five vertebrae between the rib cage and the pelvis. They are the largest segments of the vertebral column and are characterized by the absence of the foramen transversarium within the transverse process (since it is only found in the cervical region) and by the absence of facets on the sides of the body (as found only in the thoracic region). They are designated L1 to L5, starting at the top. The lumbar vertebrae help support the weight of the body, and permit movement. Human anatomy General characteristics The adjacent figure depicts the general characteristics of the first through fourth lumbar vertebrae. The fifth vertebra contains certain peculiarities, which are detailed below. As with other vertebrae, each lumbar vertebra consists of a ''vertebral body'' and a ''vertebral arch''. The vertebral arch, consisting of a pair of ''pedicles'' and a pair of ''laminae'', encloses the ''vertebral foramen'' (opening) and sup ...
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Royal Veterinary College
, mottoeng = Confront disease at onset , established = (became a constituent part of University of London in 1949) , endowment = £10.5 million (2021) , budget = £106.0 million (2020-21) , type = Public veterinary school , chancellor = The Princess Royal (University of London) , principal = Stuart Reid , students = () , undergrad = () , postgrad = () , city = London and Hertfordshire , state = , country = United Kingdom , campus = Urban , colours = , mascot = , affiliations = University of LondonUniversities UK , website www.rvc.ac.uk/ , logo = , image_name = The_Royal_Veterinary_College_crest.png The Royal Veterinary College (informally the RVC) ...
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University College London
, mottoeng = Let all come who by merit deserve the most reward , established = , type = Public research university , endowment = £143 million (2020) , budget = £1.544 billion (2019/20) , chancellor = Anne, Princess Royal(as Chancellor of the University of London) , provost = Michael Spence , head_label = Chair of the council , head = Victor L. L. Chu , free_label = Visitor , free = Sir Geoffrey Vos , academic_staff = 9,100 (2020/21) , administrative_staff = 5,855 (2020/21) , students = () , undergrad = () , postgrad = () , coordinates = , campus = Urban , city = London, England , affiliations = , colours = Purple and blue celeste , nickname ...
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