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Ann Silver
Ann Silver (born 23 November 1929) is an eminent British physiologist, known for her pioneering work on the neurotransmitter acetylcholine. She wrote a seminal text on the ''Biology of cholinesterases'' in 1974 and helped to lay the foundations of the cholinergic hypothesis by mapping cholinergic systems and helping to emphasise the importance of these pathways in brain areas central to cognitive and memory functions, leading to the use of cholinesterase inhibitors in the treatment of Alzheimer's disease. Family Ann Silver was born at a British hospital in India where her father was serving in the Indian army. Although a baptismal certificate states that she was "said to be born" on 23 November 1929, no actual birth certificate was issued. Her father was born in Grenada, then part of the British West Indies, where his Scottish father was a Church of Scotland minister. The family returned to Britain in 1930 and settled in Suffolk. She has an older brother, Ian A. Silver, who ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
University Of Edinburgh
The University of Edinburgh ( sco, University o Edinburgh, gd, Oilthigh Dhùn Èideann; abbreviated as ''Edin.'' in post-nominals) is a public research university based in Edinburgh, Scotland. Granted a royal charter by King James VI in 1582 and officially opened in 1583, it is one of Scotland's four ancient universities and the sixth-oldest university in continuous operation in the English-speaking world. The university played an important role in Edinburgh becoming a chief intellectual centre during the Scottish Enlightenment and contributed to the city being nicknamed the " Athens of the North." Edinburgh is ranked among the top universities in the United Kingdom and the world. Edinburgh is a member of several associations of research-intensive universities, including the Coimbra Group, League of European Research Universities, Russell Group, Una Europa, and Universitas 21. In the fiscal year ending 31 July 2021, it had a total income of £1.176 billion, of ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
John Gaddum
Sir John Henry Gaddum (31 March 1900 – 30 June 1965) was an English pharmacologist who, with Ulf von Euler, co-discovered the neuropeptide Substance P in 1931. He was a founder member of the British Pharmacological Society and first editor of the ''British Journal of Pharmacology''. Early life and education He was born in Hale (now part of Manchester) the son of silk merchant, Henry Edwin Gaddum and his wife Phyllis Mary Barratt. He was educated at Moorland House School, Heswall, Cheshire; Rugby School; and Trinity College, Cambridge. He completed his BSc in Physiology at the University of Cambridge in 1922, and his MD at University College London in 1925. His first role was to assist J. W, Trevan at the Wellcome Physiological Research Laboratories. Career From 1927–33, Gaddum worked under Henry Dale at the National Institute for Medical Research, and helped develop the classical laws of drug antagonism. He showed that sympathetic nerves release adrenaline. Together ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
1929 Births
Nineteen or 19 may refer to: * 19 (number), the natural number following 18 and preceding 20 * one of the years 19 BC, AD 19, 1919, 2019 Films * ''19'' (film), a 2001 Japanese film * ''Nineteen'' (film), a 1987 science fiction film Music * 19 (band), a Japanese pop music duo Albums * ''19'' (Adele album), 2008 * ''19'', a 2003 album by Alsou * ''19'', a 2006 album by Evan Yo * ''19'', a 2018 album by MHD * ''19'', one half of the double album ''63/19'' by Kool A.D. * ''Number Nineteen'', a 1971 album by American jazz pianist Mal Waldron * ''XIX'' (EP), a 2019 EP by 1the9 Songs * "19" (song), a 1985 song by British musician Paul Hardcastle. * "Nineteen", a song by Bad4Good from the 1992 album '' Refugee'' * "Nineteen", a song by Karma to Burn from the 2001 album ''Almost Heathen''. * "Nineteen" (song), a 2007 song by American singer Billy Ray Cyrus. * "Nineteen", a song by Tegan and Sara from the 2007 album '' The Con''. * "XIX" (song), a 2014 song by Slip ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Women Physiologists
A woman is an adult female human. Prior to adulthood, a female human is referred to as a girl (a female child or adolescent). The plural ''women'' is sometimes used in certain phrases such as "women's rights" to denote female humans regardless of age. Typically, women inherit a pair of X chromosomes, one from each parent, and are capable of pregnancy and giving birth from puberty until menopause. More generally, sex differentiation of the female fetus is governed by the lack of a present, or functioning, SRY-gene on either one of the respective sex chromosomes. Female anatomy is distinguished from male anatomy by the female reproductive system, which includes the ovaries, fallopian tubes, uterus, vagina, and vulva. A fully developed woman generally has a wider pelvis, broader hips, and larger breasts than an adult man. Women have significantly less facial and other body hair, have a higher body fat composition, and are on average shorter and less muscular than men. Througho ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
British Physiologists
British may refer to: Peoples, culture, and language * British people, nationals or natives of the United Kingdom, British Overseas Territories, and Crown Dependencies. ** Britishness, the British identity and common culture * British English, the English language as spoken and written in the United Kingdom or, more broadly, throughout the British Isles * Celtic Britons, an ancient ethno-linguistic group * Brittonic languages, a branch of the Insular Celtic language family (formerly called British) ** Common Brittonic, an ancient language Other uses *''Brit(ish)'', a 2018 memoir by Afua Hirsch *People or things associated with: ** Great Britain, an island ** United Kingdom, a sovereign state ** Kingdom of Great Britain (1707–1800) ** United Kingdom of Great Britain and Ireland (1801–1922) See also * Terminology of the British Isles * Alternative names for the British * English (other) * Britannic (other) * British Isles * Brit (other) * Briton (d ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Alumni Of The University Of Edinburgh
This is a list of notable graduates as well as non-graduate former students, academic staff, and university officials of the University of Edinburgh in Scotland. It also includes those who may be considered alumni by extension, having studied at institutions that later merged with the University of Edinburgh. The university is associated with 19 Nobel Prize laureates, three Turing Award winners, an Abel Prize laureate and Fields Medallist, four Pulitzer Prize winners, three Prime Ministers of the United Kingdom, and several Olympic gold medallists. Government and politics Heads of state and government United Kingdom Cabinet and Party Leaders Scottish Cabinet and Party Leaders Current Members of the House of Commons * Wendy Chamberlain, MP for North East Fife * Joanna Cherry, MP for Edinburgh South West * Colin Clark, MP for Gordon * Anneliese Dodds, MP for Oxford East * Kate Green, MP for Stretford and Urmston * John Howell, MP for Henley * Neil Hudson, M ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
The Journal Of Physiology
''The Journal of Physiology'' is a biweekly peer-reviewed scientific journal that was established in 1878 and is published by Wiley-Blackwell on behalf of The Physiological Society. It covers research on all aspects of physiology, with an emphasis on human and mammalian physiology, including work at the molecular level, at the level of the cell membrane, single cells, tissues or organs, and systems physiology. The journal is produced both on paper and online. Accepted articles are first published online, ahead of print. The full archive back to 1878 up to issues published 12 months from the current date is freely available online. The editor-in-chief is currently Peter Kohl. According to the ''Journal Citation Reports'', the journal has a 2021 impact factor of 6.228, ranking it ninth out of 84 journals in the category "Physiology" History ''The Journal of Physiology'' was first published in 1878 and edited by Michael Foster. In 1893–94 Foster's colleague John Newport Langle ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Krešimir Krnjević
Krešimir Krnjević (7 September 1927 – 16 April 2021) was a Canadian- British neurophysiologist of Croatian extraction. Life and work Krnjević was born in Zagreb in the family of prominent politician Juraj Krnjević and spent most of his childhood abroad, including in Geneva, London and Cape Town. He attended the University of Edinburgh earning MBChb in 1949, BSc in physiology in 1951 and PhD in 1953 all at the University of Edinburgh. He continued his post-doctoral studies at the University of Washington, Seattle, 1954–1956, and at the John Curtin School of Medical Research, Australian National University, Canberra, 1956-1958 after which he returned to the UK as Senior Principal Scientist Research Office at Babraham Institute, Cambridge. After an invitation to be a visiting professor at McGill University, Canada in 1964 he remained there as McGill's Director of Anesthesia Research Department until 1999 and professor of physiology from 1978 to 1987. He gained wo ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Marthe Vogt
Marthe Louise Vogt (September 8, 1903 – September 9, 2003) was a German scientist recognized as one of the leading neuroscientists of the twentieth century. She is mainly remembered for her important contributions to the understanding of the role of neurotransmitters in the brain, especially epinephrine. Early life and education Vogt was born in Berlin, the daughter of two of Germany's leading anatomists, Cécile and Oskar Vogt (French and Danish-German respectively). She was the older sister of Marguerite Vogt. Marthe studied medicine and chemistry at Berlin University (1922–1927), earning her degree as Doctor of Medicine with research on the microscopial anatomy of the human brain. She also earned a D.Phil in chemistry for research in biochemistry on carbohydrate metabolism at the Kaiser Wilhelm Institut für Biochemie under C. Neuberg (1927–1929). Career In 1929, she began work on pharmacology and endocrinology in the Institute of Pharmacology in Berlin unde ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Babraham Institute
The Babraham Institute is a life sciences research institution and a partner organisation of the University of Cambridge. The Babraham Institute is based on the Babraham Research Campus, partly occupying a former manor house, but also laboratory and science facility buildings on the campus, surrounded by an extensive parkland estate, just south of Cambridge, England. It is an independent and charitable organization which is involved in biomedical research, including healthy aging and molecular biology. The director is Dr Simon Cook who also leads the Institute's signalling research programme. The Babraham Institute is a member of EU-LIFE, an alliance of leading life sciences research centres in Europe. History The institute is located on the historic Babraham Hall Estate (now called the Babraham Research Campus), situated six miles south-east of Cambridge University, near the Gog Magog Hills. It is close to where the ancient Roman Via Devana crossed the prehistoric Ickni ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Cholinesterases
The enzyme cholinesterase (EC 3.1.1.8, choline esterase; systematic name acylcholine acylhydrolase) catalyses the hydrolysis of choline-based esters: : an acylcholine + H2O = choline + a carboxylate Several of these serve as neurotransmitters. Thus, it is either of two enzymes that catalyze the hydrolysis of these cholinergic neurotransmitters, such as breaking acetylcholine into choline and acetic acid. These reactions are necessary to allow a cholinergic neuron to return to its resting state after activation. For example, in muscle contraction, acetylcholine at a neuromuscular junction triggers a contraction; but for the muscle to relax afterward, rather than remaining locked in a tense state, the acetylcholine must be broken down by a choline esterase. The main type for that purpose is acetylcholinesterase (also called choline esterase I or erythrocyte cholinesterase); it is found mainly in chemical synapses and red blood cell membranes. The other type is butyrylcholinestera ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Wide View Of Babraham Institute Buildings
{{Disambiguation, callsign ...
WIDE or Wide may refer to: * Wide (cricket) * Wide and narrow data, terms used to describe two different presentations for tabular data * WIDE Project, Widely Integrated Distributed Environment * Wide-angle Infinity Display Equipment * WIDE-LP, a radio station (99.1 FM) licensed to Madison, Wisconsin * Women in Development Europe; see * wide (tennis), meaning beyond the sidelines People with the name Wide * Ernst Wide (1888–1950), a Swedish Olympic long-distance runner * Edvin Wide (1896–1996), a Swedish Olympic long-distance runner * Samuel Wide (1861–1918), a Swedish archaeologist See also * * * * Widen *Width (other) Width is a measure of distance from side to side, measuring across an object at right angles to the length. Width may also refer to: Graph theory * Width of a partial order - the cardinality of a maximum antichain. * Width of a tree decomposit ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
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