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Ann McKee
Ann McKee (born 1953) is a neuropathologist and expert in neurodegenerative disease at the New England Veterans Affairs Medical Centers (VISN-1) and is professor of neurology and pathology at Boston University School of Medicine and director of Boston University CTE Center. She is particularly known for her work studying Alzheimer's disease and the consequences of repetitive traumatic brain injury. In 2017, she was named "Bostonian of the Year" by '' The Boston Globe'' for her leading work in this area, and in 2018, ''Time'' named McKee one of its 100 most influential people. Education McKee earned her bachelor's degree at the University of Wisconsin and her medical degree at Case Western Reserve University School of Medicine. McKee then completed a fellowship in neuropathology at Massachusetts General Hospital and a residency in neurology at Cleveland Metropolitan General Hospital. Career McKee is the chief neuropathologist at New England Veterans Affairs Medical Cente ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Appleton, Wisconsin
Appleton ( mez, Ahkōnemeh) is a city in Outagamie, Calumet, and Winnebago counties in the U.S. state of Wisconsin. One of the Fox Cities, it is situated on the Fox River, southwest of Green Bay and north of Milwaukee. Appleton is the county seat of Outagamie County. As of the 2020 Census it had a population of 75,644, making it the sixth largest city in Wisconsin. Appleton is a part of the Fox Cities metropolitan area, the third largest in the state behind Milwaukee and Madison. Appleton serves as the heart of the Fox River Valley, which is home to Lawrence University, the Fox Cities Exhibition Center, Fox Cities Performing Arts Center, Fox River Mall, Neuroscience Group Field at Fox Cities Stadium, Appleton International Airport, and the Valley's two major hospitals: St. Elizabeth Hospital and ThedaCare Regional Medical Center–Appleton. It also hosts regional events such as Octoberfest and the Mile of Music. History Native American history The territory wh ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Massachusetts General Hospital
Massachusetts General Hospital (Mass General or MGH) is the original and largest teaching hospital of Harvard Medical School located in the West End neighborhood of Boston, Massachusetts. It is the third oldest general hospital in the United States and has a capacity of 999 beds. With Brigham and Women's Hospital, it is one of the two founding members of Mass General Brigham (formerly known as Partners HealthCare), the largest healthcare provider in Massachusetts. Massachusetts General Hospital houses the largest hospital-based research program in the world, the Mass General Research Institute, with an annual research budget of more than $1 billion in 2019. It is currently ranked as the #8 best hospital in the United States by '' U.S. News & World Report''. In , ''The Boston Globe'' ranked MGH the fifth best place to work out of Massachusetts companies with over 1,000 employees. History Founded in 1811, the original hospital was designed by the famous American architect Char ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Parkinson's Disease
Parkinson's disease (PD), or simply Parkinson's, is a long-term degenerative disorder of the central nervous system that mainly affects the motor system. The symptoms usually emerge slowly, and as the disease worsens, non-motor symptoms become more common. The most obvious early symptoms are tremor, rigidity, slowness of movement, and difficulty with walking. Cognitive and behavioral problems may also occur with depression, anxiety, and apathy occurring in many people with PD. Parkinson's disease dementia becomes common in the advanced stages of the disease. Those with Parkinson's can also have problems with their sleep and sensory systems. The motor symptoms of the disease result from the death of cells in the substantia nigra, a region of the midbrain, leading to a dopamine deficit. The cause of this cell death is poorly understood, but involves the build-up of misfolded proteins into Lewy bodies in the neurons. Collectively, the main motor symptoms are also known as ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Lewy Body Disease
Lewy body dementias are two similar and common subtypes of dementia— dementia with Lewy bodies (DLB) and Parkinson's disease dementia (PDD). Both are characterized by changes in thinking, movement, behavior, and mood. The two conditions have similar features and may have similar causes, and are believed to belong on a spectrum of Lewy body disease that includes Parkinson's disease. As of 2014, they were more often misdiagnosed than any other common dementia. The exact cause is unknown, but involves widespread deposits of abnormal clumps of protein that form in neurons of the diseased brain. Known as Lewy bodies (discovered in 1912 by Frederic Lewy) and Lewy neurites, these clumps affect both the central nervous system and the autonomic nervous system. The fifth revision of the ''Diagnostic and Statistical Manual of Mental Disorders'' ( DSM-5) gives Lewy body disease as the causative subtype of dementia with Lewy bodies, and Parkinson's disease as the causative subtype o ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
United States House Committee On The Judiciary
The U.S. House Committee on the Judiciary, also called the House Judiciary Committee, is a standing committee of the United States House of Representatives. It is charged with overseeing the administration of justice within the federal courts, administrative agencies and Federal law enforcement entities. The Judiciary Committee is also the committee responsible for impeachments of federal officials. Because of the legal nature of its oversight, committee members usually have a legal background, but this is not required. In the 117th Congress, the chairman of the committee is Democrat Jerry Nadler of New York, and the ranking minority member is Republican Jim Jordan of Ohio. History The committee was created on June 3, 1813 for the purpose of considering legislation related to the judicial system. This committee approved articles of impeachment against Presidents in five instances: Andrew Johnson (1867 and 1868), Richard Nixon (1974), Bill Clinton (1998), and Donald Trump (2 ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
National Football League
The National Football League (NFL) is a professional American football league that consists of 32 teams, divided equally between the American Football Conference (AFC) and the National Football Conference (NFC). The NFL is one of the major professional sports leagues in the United States and Canada and the highest professional level of American football in the world. Each NFL season begins with a three-week preseason in August, followed by the 18-week regular season which runs from early September to early January, with each team playing 17 games and having one bye week In sport, a bye is the preferential status of a player or team that is automatically advanced to the next round of a tournament, without having to play an opponent in an early round. In knockout (elimination) tournaments they can be granted eit .... Following the conclusion of the regular season, seven teams from each conference (four division winners and three wild card teams) advance to the p ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Enforcer (ice Hockey)
Enforcer is an unofficial role in ice hockey. The term is sometimes used synonymously with "fighter", "tough guy", or "goon". An enforcer's job is to deter and respond to dirty or violent play by the opposition. When such play occurs, the enforcer is expected to respond aggressively, by fighting or checking the offender. Enforcers are expected to react particularly harshly to violence against star players or goalies. Enforcers are different from pests, players who seek to agitate opponents and distract them from the game, without necessarily fighting them. The pest's primary role is to draw penalties from opposing players, thus "getting them off their game", while not actually intending to fight the opposition player (although exceptions to this do occur). Pests and enforcers often play together on the same line, usually the fourth line. National Hockey League At present in the National Hockey League (NHL), teams generally do not carry more than one player whose primary role is ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Contact Sport
Contact sports are sports that emphasize or require physical contact between players. Some sports, such as mixed martial arts, are scored on impacting an opponent, while others, including rugby football, gridiron football and Australian rules football, require tackling of players. These sports are often known as full-contact, as the sport cannot be undertaken without contact. Some sports, such as baseball and kho-kho, only allow physical contact in the form of tagging (lightly touching) opponents. Some contact sports have non-contact variations (such as flag football for American football) which replace tackling and other forms of contact with alternative methods of interacting with an opponent, such as removing a flag from a belt worn by the opponent. Other sports may have contact, but such events are illegal under the rules of the game and are incidental or accidental and do not form part of the sport. It can also include impact via a piece of sporting equipment, such as bein ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Ice Hockey
Ice hockey (or simply hockey) is a team sport played on ice skates, usually on an ice skating rink with lines and markings specific to the sport. It belongs to a family of sports called hockey. In ice hockey, two opposing teams use ice hockey sticks to control, advance and shoot a closed, vulcanized, rubber disc called a " puck" into the other team's goal. Each goal is worth one point. The team which scores the most goals is declared the winner. In a formal game, each team has six skaters on the ice at a time, barring any penalties, one of whom is the goaltender. Ice hockey is a full contact sport. Ice hockey is one of the sports featured in the Winter Olympics while its premiere international amateur competition, the IIHF World Championships, are governed by the International Ice Hockey Federation (IIHF) for both men's and women's competitions. Ice hockey is also played as a professional sport. In North America as well as many European countries, the sport is known simply ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
American Football
American football (referred to simply as football in the United States and Canada), also known as gridiron, is a team sport played by two teams of eleven players on a rectangular field with goalposts at each end. The offense, the team with possession of the oval-shaped football, attempts to advance down the field by running with the ball or passing it, while the defense, the team without possession of the ball, aims to stop the offense's advance and to take control of the ball for themselves. The offense must advance at least ten yards in four downs or plays; if they fail, they turn over the football to the defense, but if they succeed, they are given a new set of four downs to continue the drive. Points are scored primarily by advancing the ball into the opposing team's end zone for a touchdown or kicking the ball through the opponent's goalposts for a field goal. The team with the most points at the end of a game wins. American football evolved in the United States, ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Boxing
Boxing (also known as "Western boxing" or "pugilism") is a combat sport in which two people, usually wearing protective gloves and other protective equipment such as hand wraps and mouthguards, throw punches at each other for a predetermined amount of time in a boxing ring. Although the term "boxing" is commonly attributed to "western boxing", in which only the fists are involved, boxing has developed in various ways in different geographical areas and cultures. In global terms, boxing is a set of combat sports focused on striking, in which two opponents face each other in a fight using at least their fists, and possibly involving other actions such as kicks, elbow strikes, Knee (strike), knee strikes, and headbutts, depending on the rules. Some of the forms of the modern sport are western boxing, Bare-knuckle boxing, bare knuckle boxing, kickboxing, Muay Thai, muay-thai, lethwei, savate, and Sanda (sport), sanda. Boxing techniques have been incorporated into many martial ar ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Neurodegeneration
A neurodegenerative disease is caused by the progressive loss of structure or function of neurons, in the process known as neurodegeneration. Such neuronal damage may ultimately involve cell death. Neurodegenerative diseases include amyotrophic lateral sclerosis, multiple sclerosis, Parkinson's disease, Alzheimer's disease, Huntington's disease, multiple system atrophy, and prion diseases. Neurodegeneration can be found in the brain at many different levels of neuronal circuitry, ranging from molecular to systemic. Because there is no known way to reverse the progressive degeneration of neurons, these diseases are considered to be incurable; however research has shown that the two major contributing factors to neurodegeneration are oxidative stress and inflammation. Biomedical research has revealed many similarities between these diseases at the subcellular level, including atypical protein assemblies (like proteinopathy) and induced cell death. These similarities suggest that ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
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