Angelo Celli
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Angelo Celli
Angelo Celli (25 March 1857 – 2 November 1914) was an Italian physician, hygienist, parasitologist and philanthropist known for his pioneering work on the malarial parasite and control of malaria. He was Professor of Hygiene at the University of Palermo, and then at the Sapienza University of Rome. He founded the Pasteur Institute of Italy. With his wife Anna Fraentzel he established a number of medical schools in the Roman Campagna and dispensaries in Rome. He and Ettore Marchiafava correctly described the protozoan parasite that caused malaria and gave it the scientific name ''Plasmodium'' in 1885. Understanding the nature of malaria, he was among the first scientists to advocate and work for eradication of insects to prevent infectious diseases. He was elected to the Senate of the Kingdom of Italy in 1892. Biography Angelo Celli graduated in medicine in 1878 at the Sapienza University of Rome. He joined the pathology department as assistant to Tommasi-Crudeli. In 1886, ...
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Cagli
Cagli is a town and ''comune'' in the province of Pesaro e Urbino, Marche, central Italy. It c. south of Urbino. The Burano flows near the town. History Cagli occupies the site of an ancient village on the Via Flaminia, which seems to have borne the name Cale, or Callium north of Helvillum (now Sigillo) and southwest of Forum Sempronii (now Fossombrone). In the 6th century it was one of the strongholds of the Byzantine Pentapolis. A free commune was founded in Cagli at the end of the 12th century, and it quickly subdued more than 52 surrounding castles, overthrowing the rural lords and threatening the feudal powers of the abbots. Its expansion established the borders of the diocese of Cagli. When the city was partially destroyed by fire, started by Ghibelline factions in 1287, the settlement was moved down from the slopes of Monte Petrano and rebuilt anew on flatter land, incorporating the pre-existing suburb. The rebuilding of the city, under the patronage of Pope Nichola ...
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Malarial Parasite
''Plasmodium'' is a genus of unicellular eukaryotes that are obligate parasites of vertebrates and insects. The life cycles of ''Plasmodium'' species involve development in a blood-feeding insect host which then injects parasites into a vertebrate host during a blood meal. Parasites grow within a vertebrate body tissue (often the liver) before entering the bloodstream to infect red blood cells. The ensuing destruction of host red blood cells can result in malaria. During this infection, some parasites are picked up by a blood-feeding insect (mosquitoes in majority cases), continuing the life cycle. ''Plasmodium'' is a member of the phylum Apicomplexa, a large group of parasitic eukaryotes. Within Apicomplexa, ''Plasmodium'' is in the order Haemosporida and family Plasmodiidae. Over 200 species of ''Plasmodium'' have been described, many of which have been subdivided into 14 subgenera based on parasite morphology and host range. Evolutionary relationships among different ''Plasm ...
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Giovanni Battista Grassi
Giovanni Battista Grassi (27 March 1854 – 4 May 1925) was an Italian physician and zoologist, best known for his pioneering works on parasitology, especially on malariology. He was Professor of Comparative Zoology at the University of Catania from 1883, and Professor of Comparative Anatomy at Sapienza University of Rome from 1895 until his death. His scientific contributions covered embryological development of honey bees, on helminth parasites, the vine parasite phylloxera, on migrations and metamorphosis in eels, and on termites. He was the first to describe and establish the life cycle of the human malarial parasite, ''Plasmodium falciparum'', and discovered that only female anopheline mosquitoes are capable of transmitting the disease. His works in malaria remain a lasting controversy in the history of Nobel Prizes, because a British army surgeon Ronald Ross, who discovered the transmission of malarial parasite in birds was given the 1902 Nobel Prize in Physiology or M ...
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Amico Bignami
Amico Bignami (15 April 1862 – 8 September 1929) was an Italian physician, pathologist, malariologist and sceptic. He was professor of pathology at Sapienza University of Rome. His most important scientific contribution was in the discovery of transmission of human malarial parasite in the mosquito. With researcher Ettore Marchiafava he described a neurological disease, which is now given the eponymous name Marchiafava–Bignami disease. Biography Amico Bignami was born in Bologna to Eugenia and Francesco Mazzoni. He earned his medical degree from University of Rome (Sapienza University of Rome) in 1887. He was immediately appointed as assistant to Tommasi Crudelli in the Institute of General Pathology, where he worked until 1891. That year he joined the Institute of Pathological Anatomy under by Ettore Marchiafava. In 1890, he became extraordinary professor of pathology at the University of Rome and was promoted to full professor in 1906. In 1917, he became professor of med ...
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Alphonse Laveran
Charles Louis Alphonse Laveran (18 June 1845 – 18 May 1922) was a French physician who won the Nobel Prize in Physiology or Medicine in 1907 for his discoveries of parasitic protozoans as causative agents of infectious diseases such as malaria and trypanosomiasis. Following his father, Louis Théodore Laveran, he took up military medicine as his profession. He obtained his medical degree from University of Strasbourg in 1867. At the outbreak of the Franco-Prussian War in 1870, he joined the French Army. At the age of 29 he became Chair of Military Diseases and Epidemics at the École de Val-de-Grâce. At the end of his tenure in 1878 he worked in Algeria, where he made his major achievements. He discovered that the protozoan parasite ''Plasmodium'' was responsible for malaria, and that ''Trypanosoma'' caused trypanosomiasis or African sleeping sickness. In 1894 he returned to France to serve in various military health services. In 1896 he joined Pasteur Institute as Chief of ...
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Protozoa
Protozoa (singular: protozoan or protozoon; alternative plural: protozoans) are a group of single-celled eukaryotes, either free-living or parasitic, that feed on organic matter such as other microorganisms or organic tissues and debris. Historically, protozoans were regarded as "one-celled animals", because they often possess animal-like behaviours, such as motility and predation, and lack a cell wall, as found in plants and many algae. When first introduced by Georg Goldfuss (originally spelled Goldfuß) in 1818, the taxon Protozoa was erected as a class within the Animalia, with the word 'protozoa' meaning "first animals". In later classification schemes it was elevated to a variety of higher ranks, including phylum, subkingdom and kingdom, and sometimes included within Protoctista or Protista. The approach of classifying Protozoa within the context of Animalia was widespread in the 19th and early 20th century, but not universal. By the 1970s, it became usual to require th ...
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Hamburg
(male), (female) en, Hamburger(s), Hamburgian(s) , timezone1 = Central (CET) , utc_offset1 = +1 , timezone1_DST = Central (CEST) , utc_offset1_DST = +2 , postal_code_type = Postal code(s) , postal_code = 20001–21149, 22001–22769 , area_code_type = Area code(s) , area_code = 040 , registration_plate = , blank_name_sec1 = GRP (nominal) , blank_info_sec1 = €123 billion (2019) , blank1_name_sec1 = GRP per capita , blank1_info_sec1 = €67,000 (2019) , blank1_name_sec2 = HDI (2018) , blank1_info_sec2 = 0.976 · 1st of 16 , iso_code = DE-HH , blank_name_sec2 = NUTS Region , blank_info_sec2 = DE6 , website = , footnotes ...
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First World War
World War I (28 July 1914 11 November 1918), often abbreviated as WWI, was one of the deadliest global conflicts in history. Belligerents included much of Europe, the Russian Empire, the United States, and the Ottoman Empire, with fighting occurring throughout Europe, the Middle East, Africa, the Pacific, and parts of Asia. An estimated 9 million soldiers were killed in combat, plus another 23 million wounded, while 5 million civilians died as a result of military action, hunger, and disease. Millions more died in genocides within the Ottoman Empire and in the 1918 influenza pandemic, which was exacerbated by the movement of combatants during the war. Prior to 1914, the European great powers were divided between the Triple Entente (comprising France, Russia, and Britain) and the Triple Alliance (containing Germany, Austria-Hungary, and Italy). Tensions in the Balkans came to a head on 28 June 1914, following the assassination of Archduke Franz Ferdina ...
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Corrado Tommasi-Crudeli
Corrado Tommasi-Crudeli (31 January 1834 to 31 May 1900) was an Italian physician known for his works in pathology and hygiene. He studied for his medical degree at the University of Pisa. He was trained in pathology under the German pathologist Rudolf Virchow. He worked in medical services at Florence, Palermo, and Rome. He was Chair of Pathology at the Sapienza University of Rome. He was known to the public for his service during cholera outbreak and in establishing hospitals, particularly the Institute for Experimental Hygiene (Istituto di Igiene Sperimentale) in Rome. He was elected to Italian Senate during 1892–1893. He, with Edwin Klebs, discovered that typhoid and diphtheria were caused by bacteria. However, they made a mistake in declaring that a bacterium (which they called ''Bacillus malariae'') was also responsible for malaria. Biography Tommasi-Crudeli was the eldest son of Peter Tommasi (the surname Tommasi-Crudeli was adopted later) and Elisa Gatteschi. His fath ...
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Senate Of The Kingdom Of Italy
The Senate of the Kingdom of Italy () was the upper house of the bicameral parliament of the Kingdom of Italy, officially created on 4 March 1848, acting as an evolution of the original Subalpine Senate. It was replaced on 1 January 1948 by the present-day Senate of the Republic. All of its members were appointed by the King. History The Senate of the Kingdom of Italy rose to national prominence in 1860, following the Unification of Italy, as the direct successor of the Subalpine Senate of the Kingdom of Sardinia, with the addition of members drawn from the territories obtained during the Second Italian War of Independence and the Expedition of the Thousand. The Senate was initially based at the Palazzo Madama in Turin until 1864, when it was moved to the Palazzo Vecchio in Florence. Finally, in 1871, it was moved to the Palazzo Madama in Rome. During the fascist regime, there was no "fascistisation" (''fascistizzazione'') of the Senate equivalent to that carried out in ...
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Infectious Diseases
An infection is the invasion of tissues by pathogens, their multiplication, and the reaction of host tissues to the infectious agent and the toxins they produce. An infectious disease, also known as a transmissible disease or communicable disease, is an illness resulting from an infection. Infections can be caused by a wide range of pathogens, most prominently bacteria and viruses. Hosts can fight infections using their immune system. Mammalian hosts react to infections with an innate response, often involving inflammation, followed by an adaptive response. Specific medications used to treat infections include antibiotics, antivirals, antifungals, antiprotozoals, and antihelminthics. Infectious diseases resulted in 9.2 million deaths in 2013 (about 17% of all deaths). The branch of medicine that focuses on infections is referred to as infectious disease. Types Infections are caused by infectious agents (pathogens) including: * Bacteria (e.g. ''Mycobacterium tuberculosis'' ...
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Ettore Marchiafava
Ettore Marchiafava (3 January 1847 – 22 October 1935) was an Italian physician, pathologist and neurologist. He spent most of his career as professor of medicine at the University of Rome (now Sapienza Università di Roma). His works on malaria laid down the foundation for modern malariology. He and Angelo Celli were the first to elucidate living malarial parasites in human blood, and able to distinguish the protozoan parasites responsible for tertian and benign malaria. In 1885 they gave the formal scientific name ''Plasmodium'' for these parasites. They also discovered meningococcus as the causative agent of cerebral and spinal meningitis. Marchiafava was the first to describe syphilitic cerebral arteritis and degeneration of brain in an alcoholic patient, which is now eponymously named Marchiafava's disease. He gave a complete description of a genetic disease of blood now known Paroxysmal nocturnal hemoglobinuria or sometimes Strübing-Marchiafava-Micheli syndrome, in h ...
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