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Androstenolone
Androstenolone may refer to: * Testosterone (androst-4-en-17β-ol-3-one), an endogenous androgen/anabolic steroid and an intermediate in the biosynthesis of estradiol * Epitestosterone (androst-4-en-17α-ol-3-one), an inactive endogenous steroid * Dehydroepiandrosterone (DHEA, 5-DHEA) (androst-4-en-3β-ol-17-one), an endogenous weak androgen, an estrogen, a neurosteroid, and an intermediate in the biosynthesis of testosterone * 1-Testosterone (androst-4-en-17β-ol-3-one), a synthetic androgen/anabolic steroid * 4-Dehydroepiandrosterone (4-DHEA) (androst-4-en-3β-ol-17-one), an androgen prohormone * 1-Androsterone (1-DHEA) (5α-androst-1-en-3β-ol-17-one), a synthetic androgen prohormone See also * Androstanolone * Androstenediol * Androstanedione * Androstanediol Androstanediol may refer to: * 3α-Androstanediol (5α-androstane-3α,17β-diol) – an endogenous neurosteroid, weak androgen and estrogen, and intermediate to androsterone * 3β-Androstanediol (5α-androstane-3β,17β ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Dehydroepiandrosterone
Dehydroepiandrosterone (DHEA), also known as androstenolone, is an endogenous steroid hormone precursor. It is one of the most abundant circulating steroids in humans. DHEA is produced in the adrenal glands, the gonads, and the brain. It functions as a metabolic intermediate in the biosynthesis of the androgen and estrogen sex steroids both in the gonads and in various other tissues. However, DHEA also has a variety of potential biological effects in its own right, binding to an array of nuclear and cell surface receptors, and acting as a neurosteroid and modulator of neurotrophic factor receptors. In the United States, DHEA is sold as an over-the-counter supplement, and medication called prasterone. Biological function As an androgen DHEA and other adrenal androgens such as androstenedione, although relatively weak androgens, are responsible for the androgenic effects of adrenarche, such as early pubic and axillary hair growth, adult-type body odor, increased oiliness of ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Androstanediol
Androstanediol may refer to: * 3α-Androstanediol (5α-androstane-3α,17β-diol) – an endogenous neurosteroid, weak androgen and estrogen, and intermediate to androsterone * 3β-Androstanediol (5α-androstane-3β,17β-diol) – an endogenous estrogen and intermediate to epiandrosterone * 3α-Etiocholanediol (5β-androstane-3α,17β-diol; etiocholane-3α,17β-diol) – an endogenous intermediate to etiocholanolone * 3β-Etiocholanediol (5β-androstane-3β,17β-diol; etiocholane-3β,17β-diol) – an endogenous intermediate to epietiocholanolone See also * Etiocholanediol * Androstenediol * Androstanedione * Androstenedione * Androstanolone * Androstenolone Androstenolone may refer to: * Testosterone (androst-4-en-17β-ol-3-one), an endogenous androgen/anabolic steroid and an intermediate in the biosynthesis of estradiol * Epitestosterone (androst-4-en-17α-ol-3-one), an inactive endogenous steroid * ... Androstanes {{Chemistry index ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Testosterone
Testosterone is the primary sex hormone and anabolic steroid in males. In humans, testosterone plays a key role in the development of Male reproductive system, male reproductive tissues such as testes and prostate, as well as promoting secondary sexual characteristics such as increased muscle and bone mass, and the growth of androgenic hair, body hair. In addition, testosterone in both sexes is involved in health and well-being, including moods, behaviour, and in the prevention of osteoporosis. Insufficient levels of testosterone in men may lead to abnormalities including frailty and bone loss. Testosterone is a steroid from the androstane class containing a ketone and a hydroxyl group at positions three and seventeen respectively. It is Biosynthesis, biosynthesized in several steps from cholesterol and is converted in the liver to inactive metabolites. It exerts its action through binding to and activation of the androgen receptor. In humans and most other vertebrates, testost ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Epitestosterone
Epitestosterone, or isotestosterone, also known as 17α-testosterone or as androst-4-en-17α-ol-3-one, is an endogenous steroid and an epimer of the androgen sex hormone testosterone. It is a weak competitive antagonist of the androgen receptor (AR) and a potent 5α-reductase inhibitor. Structurally, epitestosterone differs from testosterone only in the configuration at the hydroxy-bearing carbon, C17. Epitestosterone is believed to form in a similar way to testosterone; a 1993 study found that around 50% of epitestosterone production in human males can be ascribed to the testis, although the exact pathway of its formation is still the subject of research. It has been shown to accumulate in mammary cyst fluid and in the prostate. Epitestosterone levels are typically highest in young males; however, by adulthood, most healthy males exhibit a testosterone to epitestosterone ratio (T/E ratio) of about 1:1. Society and culture Detection of athletic doping It has been shown that exog ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
1-Testosterone
1-Testosterone (abbreviated and nicknamed as 1-Testo, 1-T), also known as δ1-dihydrotestosterone (δ1-DHT), as well as dihydroboldenone, is a synthetic anabolic–androgenic steroid (AAS) and a 5α-reduced derivative of boldenone (Δ1-testosterone). It differs from testosterone by having a 1(2)-double bond instead of a 4(5)-double bond in its A ring. It was legally sold online in the United States until 2005, when it was reclassified as a Schedule III drug. Side effects Pharmacology Pharmacodynamics A 2006 study determined that 1-testosterone has a high androgenic and anabolic potency even without being metabolized, so it can be characterized as a typical anabolic steroid. 1-Testosterone binds in a manner that is highly selective to the androgen receptor (AR) and has a high potency to stimulate AR-dependent transactivation. ''In vivo'', an equimolar dose of 1-testosterone has the same potency to stimulate the growth of the prostate, the seminal vesicles and the androge ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
4-Dehydroepiandrosterone
4-Dehydroepiandrosterone (4-DHEA) is a steroid that is an isomer of 5-dehydroepiandrosterone Dehydroepiandrosterone (DHEA), also known as androstenolone, is an endogenous steroid hormone precursor. It is one of the most abundant circulating steroids in humans. DHEA is produced in the adrenal glands, the gonads, and the brain. It func .... 4-DHEA has been prepared by laboratory synthesis.Ward, Margaret G.; Orr, James C.; Engel, Lewis L. A convenient synthesis of 3β-hydroxyandrost-4-en-17-one. Journal of Organic Chemistry (1965), 30(5), 1421-3. Synonyms Synonyms for 4-dehydroepiandrosterone are: 3β-Hydroxy-4-androsten-17-one, 3β-hydroxyandrost-4-en-17-one, 3β-hydroxy-D4-androsten-17-one, 3β-hydroxyandrost-4-en-17-one, 3β-hydroxy-etioallocholan-4-en-17-one, and 4-androsten-3β-ol-17-one. References Sterols Androgens and anabolic steroids Androstanes Ketones {{steroid-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
1-Androsterone
1-Androsterone (also known as 1-andro, 1-dehydroepiandrosterone, 1-DHEA, δ1-epiandrosterone, or 5α-androst-1-en-3β-ol-17-one) is a synthetic, orally active anabolic-androgenic steroid (AAS). It is an androgen prohormone of 1-testosterone (dihydroboldenone), 1-androstenedione, and other 1-dehydrogenated androstanes. The drug has been sold on the Internet as a designer steroid and "dietary supplement". It is a positional isomer of dehydroepiandrosterone (DHEA; 5-dehydroepiandrosterone). See also * 4-Dehydroepiandrosterone * Androsterone * Epiandrosterone Epiandrosterone, or isoandrosterone, also known as 3β-androsterone, 3β-hydroxy-5α-androstan-17-one, or 5α-androstan-3β-ol-17-one, is a steroid hormone with weak androgenic activity. It is a metabolite of testosterone and dihydrotestosterone ... References Sterols Androgens and anabolic steroids Androstanes Ketones Prodrugs {{Genito-urinary-drug-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Androstanolone
Androstanolone, or stanolone, also known as dihydrotestosterone (DHT) and sold under the brand name Andractim among others, is an androgen and anabolic steroid (AAS) medication and hormone which is used mainly in the treatment of low testosterone levels in men. It is also used to treat breast development and small penis in males. It is typically given as a gel for application to the skin, but can also be used as an ester by injection into muscle. Side effects of androstanolone include symptoms of masculinization like acne, increased hair growth, voice changes, and increased sexual desire. The medication is a naturally occurring androgen and anabolic steroid and hence is an agonist of the androgen receptor (AR), the biological target of androgens like testosterone and DHT. It has strong androgenic effects and weak muscle-building effects, as well as no estrogenic effects. Androstanolone was discovered in 1935 and was introduced for medical use in 1953. It is used mostly i ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Androstenediol
Androstenediol, or 5-androstenediol (abbreviated as A5 or Δ5-diol), also known as androst-5-ene-3β,17β-diol, is an endogenous weak androgen and estrogen steroid hormone and intermediate in the biosynthesis of testosterone from dehydroepiandrosterone (DHEA). It is closely related to androstenedione (androst-4-ene-3,17-dione). Biological activity Androstenediol is a direct metabolite of the most abundant steroid produced by the human adrenal cortex, DHEA. It is less androgenic than the related compound, Δ4-androstenediol, and has been found to stimulate the immune system. When administered to rats, androstenediol, ''in vivo'', has approximately 1.4% of the androgenicity of DHEA, 0.54% of the androgenicity of androstenedione, and 0.21% of the androgenicity of testosterone. Androstenediol possesses potent estrogenic activity, similarly to DHEA and 3β-androstanediol. It has approximately 6% and 17% of the affinity of estradiol at the ERα and ERβ, respectively. Although and ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Androstanedione
Androstanedione, also known as 5α-androstanedione or as 5α-androstane-3,17-dione, is a naturally occurring androstane (5α-androstane) steroid and an endogenous metabolite of androgens like testosterone, dihydrotestosterone (DHT), dehydroepiandrosterone (DHEA), and androstenedione. It is the C5 epimer of etiocholanedione (5β-androstanedione). Androstanedione is formed from androstenedione by 5α-reductase and from DHT by 17β-hydroxysteroid dehydrogenase. It has some androgen An androgen (from Greek ''andr-'', the stem of the word meaning "man") is any natural or synthetic steroid hormone that regulates the development and maintenance of male characteristics in vertebrates by binding to androgen receptors. This inc ...ic activity. In female genital skin, the conversion of androstenedione into DHT through 5α-androstanedione appears to be more important than the direct conversion of testosterone into DHT. References External links Androstanedione (HMDB0000899) - Human ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Androstenedione
Androstenedione, or 4-androstenedione (abbreviated as A4 or Δ4-dione), also known as androst-4-ene-3,17-dione, is an endogenous weak androgen steroid hormone and intermediate in the biosynthesis of estrone and of testosterone from dehydroepiandrosterone (DHEA). It is closely related to androstenediol (androst-5-ene-3β,17β-diol). Biological function Androstenedione is a precursor of testosterone and other androgens, as well as of estrogens like estrone, in the body. In addition to functioning as an endogenous prohormone, androstenedione also has weak androgenic activity in its own right. Androstenedione has been found to possess some estrogenic activity, similarly to other DHEA metabolites. However, in contrast to androstenediol, its affinity for the estrogen receptors is very low, with less than 0.01% of the affinity of estradiol for both the ERα and ERβ. Adrenarche In children aged 6 to 8 years old, there is a rise in androstenedione secretion along with DHEA during adr ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
