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Alu Repeat
An Alu element is a short stretch of DNA originally characterized by the action of the ''Arthrobacter luteus (Alu)'' restriction endonuclease. ''Alu'' elements are the most abundant transposable elements, containing over one million copies dispersed throughout the human genome. ''Alu'' elements were thought to be selfish or parasitic DNA, because their sole known function is self reproduction. However, they are likely to play a role in evolution and have been used as genetic markers. They are derived from the small cytoplasmic 7SL RNA, a component of the signal recognition particle. ''Alu'' elements are highly conserved within primate genomes and originated in the genome of an ancestor of Supraprimates. ''Alu'' insertions have been implicated in several inherited human diseases and in various forms of cancer. The study of Alu elements has also been important in elucidating human population genetics and the evolution of primates, including the evolution of humans. Alu fam ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Arthrobacter Luteus
''Arthrobacter luteus'' (ALU) is a species of gram-positive bacteria in the genus '' Arthrobacter''. ''A. luteus'' is facultatively anaerobic, pleomorphic, branching, non-motile, non-sporulating, non-acid-fast, catalase-positive, and rod-shaped (0.6–1.0 μm × 0.8–10.0 μm). A restriction endonuclease enzyme is extracted from the bacterium and acts at the centre of a palindromic tetranucleotide sequence to give even-ended duplex DNA fragments phosphorylated at the 5'-end. The restriction site ''Alu-I'' itself is a 4-base cutter: AG/CT. The Alu retrotransposon is named after the bacterium's abbreviation. The bacterium is also used to produce zymolyase, which can degrade yeast cell wall. Background ''Arthrobacter luteus'' was isolated from brewery sewage in research done in Takasaki, Japan in 1969. The team studied the bacteria isolated taxonomically and found them to be gram-positive, facultatively anaerobic, pleomorphic, branching, non-motile, non-sporulating, non-a ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
SRP RNA
The signal recognition particle RNA, (also known as 7SL, 6S or 4.5S RNA) is part of the signal recognition particle (SRP) ribonucleoprotein complex. SRP recognizes the signal peptide and binds to the ribosome, halting protein synthesis. Signal recognition particle receptor, is a protein that is embedded in a membrane, and which contains a Transmembrane channels, transmembrane pore. When the complex binds to , SRP releases the ribosome and drifts away. The ribosome resumes protein synthesis, but now the protein is moving through the transmembrane pore. In this way SRP directs the movement of proteins within the Cell (biology), cell to bind with a transmembrane pore which allows the protein to cross the membrane to where it is needed. The RNA and protein components of this complex are highly Conserved sequence, conserved but do vary between the different Kingdom (biology), kingdoms of life. The common Short interspersed nuclear element, SINE family Alu sequence, Alu probably or ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Cytosine
Cytosine () ( symbol C or Cyt) is one of the four nucleobases found in DNA and RNA, along with adenine, guanine, and thymine (uracil in RNA). It is a pyrimidine derivative, with a heterocyclic aromatic ring and two substituents attached (an amine group at position 4 and a keto group at position 2). The nucleoside of cytosine is cytidine. In Watson-Crick base pairing, it forms three hydrogen bonds with guanine. History Cytosine was discovered and named by Albrecht Kossel and Albert Neumann in 1894 when it was hydrolyzed from calf thymus tissues. A structure was proposed in 1903, and was synthesized (and thus confirmed) in the laboratory in the same year. In 1998, cytosine was used in an early demonstration of quantum information processing when Oxford University researchers implemented the Deutsch-Jozsa algorithm on a two qubit nuclear magnetic resonance quantum computer (NMRQC). In March 2015, NASA scientists reported the formation of cytosine, along with uracil and thym ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Guanine
Guanine () ( symbol G or Gua) is one of the four main nucleobases found in the nucleic acids DNA and RNA, the others being adenine, cytosine, and thymine (uracil in RNA). In DNA, guanine is paired with cytosine. The guanine nucleoside is called guanosine. With the formula C5H5N5O, guanine is a derivative of purine, consisting of a fused pyrimidine-imidazole ring system with conjugated double bonds. This unsaturated arrangement means the bicyclic molecule is planar. Properties Guanine, along with adenine and cytosine, is present in both DNA and RNA, whereas thymine is usually seen only in DNA, and uracil only in RNA. Guanine has two tautomeric forms, the major keto form (see figures) and rare enol form. It binds to cytosine through three hydrogen bonds. In cytosine, the amino group acts as the hydrogen bond donor and the C-2 carbonyl and the N-3 amine as the hydrogen-bond acceptors. Guanine has the C-6 carbonyl group that acts as the hydrogen bond acceptor, while a group at N ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Signal Recognition Particle RNA
The signal recognition particle RNA, (also known as 7SL, 6S or 4.5S RNA) is part of the signal recognition particle (SRP) ribonucleoprotein complex. SRP recognizes the signal peptide and binds to the ribosome, halting protein synthesis. Signal recognition particle receptor, is a protein that is embedded in a membrane, and which contains a Transmembrane channels, transmembrane pore. When the complex binds to , SRP releases the ribosome and drifts away. The ribosome resumes protein synthesis, but now the protein is moving through the transmembrane pore. In this way SRP directs the movement of proteins within the Cell (biology), cell to bind with a transmembrane pore which allows the protein to cross the membrane to where it is needed. The RNA and protein components of this complex are highly Conserved sequence, conserved but do vary between the different Kingdom (biology), kingdoms of life. The common Short interspersed nuclear element, SINE family Alu sequence, Alu probably or ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
