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Alpha-mannosidase
alpha-Mannosidase (, ''alpha-D-mannosidase'', ''p-nitrophenyl-alpha-mannosidase'', ''alpha-D-mannopyranosidase'', ''1,2-alpha-mannosidase'', ''1,2-alpha-D-mannosidase'', ''exo-alpha-mannosidase'') is an enzyme Enzymes () are proteins that act as biological catalysts (biocatalysts). Catalysts accelerate chemical reactions. The molecules upon which enzymes may act are called substrate (chemistry), substrates, and the enzyme converts the substrates in ... involved in the cleavage of the alpha form of mannose Mannose is a sugar monomer of the hexose, aldohexose series of carbohydrates. It is a C-2 epimer of glucose. Mannose is important in human metabolism, especially in the glycosylation of certain proteins. Several Congenital disorder of glycosylati .... Its systematic nameA systematic name is a name given in a systematic way to one unique group, organism, object or chemical substance A chemical substance is a form of matter In classical physics and general chemi ...
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Alpha-mannosidosis
Alpha-mannosidosis is a lysosomal storage disorder, first described by Swedish physician Okerman in 1967.''Malm D, Nilssen O (2008). "Alpha-mannosidosis". Orphanet J Rare Dis. 3 (1): 21. Digital object identifier, doi:10.1186/1750-1172-3-21. PubMed Central, PMC 2515294 . PubMed Identifier, PMID 18651971'' In humans it is known to be caused by an autosomal recessive genetic mutation in the gene MAN2B1, located on chromosome 19, affecting the production of the enzyme alpha-D-mannosidase, resulting in its deficiency.''Alpha-Mannosidosis Mutation Database. Tromsoe University. Available at: https://apex.jupiter.no/apex/f?p=101:1.'' Consequently, if both parents are carriers, there will be a 25% chance with each pregnancy that the defective gene from both parents will be inherited, and the child will suffer from the disease. There is a two in three chance that unaffected siblings will be carriers (Figure 1). In livestock alpha-mannosidosis is caused by chronic poisoning with swainsoni ...
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MAN2B2
Epididymis-specific alpha-mannosidase is an enzyme that in humans is encoded by the ''MAN2B2'' gene. Epididymis-specific alpha-mannosidase precursor Mannosidase alpha class 2B member core-specific lysosomal 1,6-alpha-D-mannosidase, alpha-1,6-Mannosidase epididymis-specific alpha-mannosidase mannosidase, alpha, class 2B, member References Further reading

* * * * * * * * * * * * * * * * * * * {{gene-4-stub ...
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Tonge Redo Alpha Mannosidase
Tonge may refer to: People *Tonge (surname) Places in England *Tonge, Bolton, an outlying area of Bolton in Greater Manchester **River Tonge, a river in Greater Manchester *Tonge, Middleton, an area of Middleton in Greater Manchester *Tonge, Kent, a village in the borough of Swale in Kent *Tonge, Leicestershire See also

* John Tonge Centre, a mortuary in Queensland, Australia * The following towns in the Netherlands: ** Nieuwe-Tonge ** Oude-Tonge * Tong (other) {{disambiguation, geo ...
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Enzyme
Enzymes () are proteins that act as biological catalysts (biocatalysts). Catalysts accelerate chemical reactions. The molecules upon which enzymes may act are called substrate (chemistry), substrates, and the enzyme converts the substrates into different molecules known as product (chemistry), products. Almost all metabolism, metabolic processes in the cell (biology), cell need enzyme catalysis in order to occur at rates fast enough to sustain life. Metabolic pathways depend upon enzymes to catalyze individual steps. The study of enzymes is called ''enzymology'' and the field of pseudoenzyme, pseudoenzyme analysis recognizes that during evolution, some enzymes have lost the ability to carry out biological catalysis, which is often reflected in their amino acid sequences and unusual 'pseudocatalytic' properties. Enzymes are known to catalyze more than 5,000 biochemical reaction types. Other biocatalysts are Ribozyme, catalytic RNA molecules, called ribozymes. Enzymes' Chemical ...
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Mannose
Mannose is a sugar Sugar is the generic name for , soluble s, many of which are used in food. Simple sugars, also called s, include , , and . Compound sugars, also called s or double sugars, are molecules made of two monosaccharides joined by a . Common examp ... monomerA monomer ( ; '' mono-'', "one" + '' -mer'', "part") is a molecule File:Pentacene on Ni(111) STM.jpg, A scanning tunneling microscopy image of pentacene molecules, which consist of linear chains of five carbon rings. A molecule is an electrical ... of the aldohexose In chemistry Chemistry is the science, scientific study of the properties and behavior of matter. It is a natural science that covers the Chemical element, elements that make up matter to the chemical compound, compounds composed of atoms, mo ... series of carbohydrate is a disaccharide A disaccharide (also called a double sugar or ''biose'') is the sugar formed when two monosaccharides are joined by glycosidic linkage. Like m ...
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List Of Enzymes
This article lists enzymes by their classification in the International Union of Biochemistry and Molecular Biology The International Union of Biochemistry and Molecular Biology (IUBMB) is an international non-governmental organisation concerned with biochemistry and molecular biology. Formed in 1955 as the International Union of Biochemistry (IUB), the union ...'s Enzyme Commission Cnumbering system. * List of EC numbers (EC 5) * List of EC numbers (EC 6) :Oxidoreductases (EC 1) (Oxidoreductase In biochemistry, an oxidoreductase is an enzyme Enzymes () are proteins that act as biological catalysts (biocatalysts). Catalysts accelerate chemical reactions. The molecules upon which enzymes may act are called substrate (chemistry), subst ...) *Dehydrogenase A dehydrogenase is an enzyme Enzymes () are proteins that act as biological catalysts (biocatalysts). Catalysts accelerate chemical reactions. The molecules upon which enzymes may act are called substrate (ch ...
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Isozymes
In biochemistry Biochemistry or biological chemistry, is the study of chemical process In a scientific Science () is a systematic enterprise that Scientific method, builds and organizes knowledge in the form of Testability, testable explanations and pr ..., isozymes (also known as isoenzymes or more generally as multiple forms of enzymes) are enzyme Enzymes () are proteins that act as biological catalysts (biocatalysts). Catalysts accelerate chemical reactions. The molecules upon which enzymes may act are called substrate (chemistry), substrates, and the enzyme converts the substrates in ...s that differ in amino acid sequence but catalyze the same chemical reaction. Isozymes usually have different kinetic parameters (e.g. different ''K''M values), or are regulated differently. They permit the fine-tuning of metabolism to meet the particular needs of a given tissue or developmental stage. In many cases, isozymes are encoded by homologous genes that have diverg ...
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