Allethrin
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Allethrin
The allethrins are a group of related synthetic compounds used in insecticides. They are classified as pyrethroids, i.e. synthetic versions of pyrethrin, a chemical with insecticidal properties found naturally in ''Chrysanthemum'' flowers. They were first synthesized in the United States by Milton S. Schechter in 1949. Allethrin was the first pyrethroid. They are commonly used in ultra-low volume sprays for outdoor mosquito control, and in many household insecticides such as Raid (insecticide), RAID, as well as mosquito coils. Chemical structure Allethrin I and allethrin II differ by having a methyl group and a methyl ester, respectively, on one terminus. Each of these allethrins consists of the eight possible stereoisomers. A partly enantiopure variant of allethrin I, consisting of only two stereoisomers in an approximate ratio of 1:1, is called bioallethrin. The same mixture of isomers, but in an approximate ratio of 3:1, is known as esbiothrin. Toxicity Chronic exposure to al ...
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Allethrin 2D
The allethrins are a group of related synthetic compounds used in insecticides. They are classified as pyrethroids, i.e. synthetic versions of pyrethrin, a chemical with insecticidal properties found naturally in ''Chrysanthemum'' flowers. They were first synthesized in the United States by Milton S. Schechter in 1949. Allethrin was the first pyrethroid. They are commonly used in ultra-low volume sprays for outdoor mosquito control, and in many household insecticides such as Raid (insecticide), RAID, as well as mosquito coils. Chemical structure Allethrin I and allethrin II differ by having a methyl group and a methyl ester, respectively, on one terminus. Each of these allethrins consists of the eight possible stereoisomers. A partly enantiopure variant of allethrin I, consisting of only two stereoisomers in an approximate ratio of 1:1, is called bioallethrin. The same mixture of isomers, but in an approximate ratio of 3:1, is known as esbiothrin. Toxicity Chronic exposure to al ...
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Allethrins
The allethrins are a group of related synthetic compounds used in insecticides. They are classified as pyrethroids, i.e. synthetic versions of pyrethrin, a chemical with insecticidal properties found naturally in ''Chrysanthemum'' flowers. They were first synthesized in the United States by Milton S. Schechter in 1949. Allethrin was the first pyrethroid. They are commonly used in ultra-low volume sprays for outdoor mosquito control, and in many household insecticides such as Raid (insecticide), RAID, as well as mosquito coils. Chemical structure Allethrin I and allethrin II differ by having a methyl group and a methyl ester, respectively, on one terminus. Each of these allethrins consists of the eight possible stereoisomers. A partly enantiopure variant of allethrin I, consisting of only two stereoisomers in an approximate ratio of 1:1, is called bioallethrin. The same mixture of isomers, but in an approximate ratio of 3:1, is known as esbiothrin. Toxicity Chronic exposure to al ...
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Esbiothrin
Bioallethrin is a brand name for an ectoparasiticide. It consists of two of the eight stereoisomers of allethrin I in an approximate ratio of 1:1. The name ''Bioallethrin'' is a registered trademark of Sumitomo Chemical. ''Esbiothrin'' (CAS number ) is a mixture of the same two stereoisomers, but in an approximate ratio of ''R'':''S'' = 1:3. ''Esbioallethrin'' or ''S-bioallethrin'' (CAS number A CAS Registry Number (also referred to as CAS RN or informally CAS Number) is a unique identification number assigned by the Chemical Abstracts Service (CAS), US to every chemical substance described in the open scientific literature. It inclu ... ) is the pure ''S''-form (that is, the wedge in the structure as shown in the box points down). The name bioallethrin is a common name approved by the British Standards Institution and published in. It is also included in British Approved Names 2017 and earlier editions. References Allethrins Allyl compounds {{antiinfective-drug ...
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Bioallethrin
Bioallethrin is a brand name for an ectoparasiticide. It consists of two of the eight stereoisomers of allethrin I in an approximate ratio of 1:1. The name ''Bioallethrin'' is a registered trademark of Sumitomo Chemical. ''Esbiothrin'' (CAS number ) is a mixture of the same two stereoisomers, but in an approximate ratio of ''R'':''S'' = 1:3. ''Esbioallethrin'' or ''S-bioallethrin'' (CAS number ) is the pure ''S''-form (that is, the wedge in the structure as shown in the box points down). The name bioallethrin is a common name approved by the British Standards Institution and published in. It is also included in British Approved Names 2017 and earlier editions. References

Allethrins Allyl compounds {{antiinfective-drug-stub ...
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Bioallethrin
Bioallethrin is a brand name for an ectoparasiticide. It consists of two of the eight stereoisomers of allethrin I in an approximate ratio of 1:1. The name ''Bioallethrin'' is a registered trademark of Sumitomo Chemical. ''Esbiothrin'' (CAS number ) is a mixture of the same two stereoisomers, but in an approximate ratio of ''R'':''S'' = 1:3. ''Esbioallethrin'' or ''S-bioallethrin'' (CAS number ) is the pure ''S''-form (that is, the wedge in the structure as shown in the box points down). The name bioallethrin is a common name approved by the British Standards Institution and published in. It is also included in British Approved Names 2017 and earlier editions. References

Allethrins Allyl compounds {{antiinfective-drug-stub ...
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Raid (insecticide)
Raid is the brand name of a line of insecticide products produced by S. C. Johnson & Son, first launched in 1956. The initial active ingredient was the first synthetic pyrethroid, allethrin. Raid derivatives aimed at particular invertebrate species can contain other active agents such as the more toxic cyfluthrin. Currently Raid Ant & Roach Killer contains pyrethroids, imiprothrin, and cypermethrin; other products contain tetramethrin, prallethrin and permethrin as active ingredients. Raid Flying Insect Killer, a spray, uses piperonyl butoxide and D-phenothrin. "Raid Kills Bugs Dead" slogan The product's original advertising tagline from its introduction in 1956 until 2017, "Raid Kills Bugs Dead", was created by the advertising agency Foote, Cone & Belding. The phrase itself is often attributed to the poet Lew Welch, who worked for the agency at the time. The line was first used in commerce in 1966 and was trademarked in 1986. Noted animation director Tex Avery was the pr ...
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Pyrethroid
A pyrethroid is an organic compound similar to the natural pyrethrins, which are produced by the flowers of pyrethrums (''Chrysanthemum cinerariaefolium'' and ''Chrysanthemum coccineum, C. coccineum''). Pyrethroids are used as commercial and household insecticides. In household concentrations pyrethroids are generally harmless to humans. However, pyrethroids are toxic to insects such as bees, dragonflies, mayflies, Horse-fly, gadflies, and some other invertebrates, including those that constitute the base of aquatic and terrestrial food webs. Pyrethroids are toxic to aquatic organisms, especially fish.Pyrethroids fact sheet
from the Illinois Department of Public Health.
They have been shown to be an effective control measure for malaria outbreaks, through indoor applications.


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Pyrethroids
A pyrethroid is an organic compound similar to the natural pyrethrins, which are produced by the flowers of pyrethrums (''Chrysanthemum cinerariaefolium'' and '' C. coccineum''). Pyrethroids are used as commercial and household insecticides. In household concentrations pyrethroids are generally harmless to humans. However, pyrethroids are toxic to insects such as bees, dragonflies, mayflies, gadflies, and some other invertebrates, including those that constitute the base of aquatic and terrestrial food webs. Pyrethroids are toxic to aquatic organisms, especially fish.Pyrethroids fact sheet
from the Illinois Department of Public Health.
They have been shown to be an effective control measure for malaria outbreaks, through indoor applications.


Mode of action

Pyrethroi ...
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Mosquito Coil
A mosquito coil is a mosquito-repelling incense, usually made into a spiral, and typically made using dried paste of pyrethrum powder. The coil is usually held at the center of the spiral, suspending it in the air, or wedged by two pieces of fireproof netting to allow continuous smoldering. Burning usually begins at the outer end of the spiral and progresses slowly toward the center of the spiral, producing a mosquito-repellent smoke. A typical mosquito coil measures around in diameter and lasts around seven to twelve hours. Mosquito coils are widely used in Asia, Africa, South America, Canada, Mexico and Australia. Invention Pyrethrum was used for centuries as an insecticide in Persia and Europe, being developed into a mosquito coil in the late 1800s by a Japanese couple: Yuki and Eiichiro Ueyama ( 上山英一郎). At that time in Japan, pyrethrum powder was mixed with sawdust and burned to repel mosquitoes. Ueyama initially created incense sticks mixed from starch powder, dr ...
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Insecticides
Insecticides are substances used to kill insects. They include ovicides and larvicides used against insect eggs and larvae, respectively. Insecticides are used in agriculture, medicine, industry and by consumers. Insecticides are claimed to be a major factor behind the increase in the 20th-century's agricultural productivity. Nearly all insecticides have the potential to significantly alter ecosystems; many are toxic to humans and/or animals; some become concentrated as they spread along the food chain. Insecticides can be classified into two major groups: systemic insecticides, which have residual or long term activity; and contact insecticides, which have no residual activity. The mode of action describes how the pesticide kills or inactivates a pest. It provides another way of classifying insecticides. Mode of action can be important in understanding whether an insecticide will be toxic to unrelated species, such as fish, birds and mammals. Insecticides may be repellent ...
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World Health Organization
The World Health Organization (WHO) is a specialized agency of the United Nations responsible for international public health. The WHO Constitution states its main objective as "the attainment by all peoples of the highest possible level of health". Headquartered in Geneva, Switzerland, it has six regional offices and 150 field offices worldwide. The WHO was established on 7 April 1948. The first meeting of the World Health Assembly (WHA), the agency's governing body, took place on 24 July of that year. The WHO incorporated the assets, personnel, and duties of the League of Nations' Health Organization and the , including the International Classification of Diseases (ICD). Its work began in earnest in 1951 after a significant infusion of financial and technical resources. The WHO's mandate seeks and includes: working worldwide to promote health, keeping the world safe, and serve the vulnerable. It advocates that a billion more people should have: universal health care coverag ...
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Glucuronosyltransferase
Uridine 5'-diphospho-glucuronosyltransferase ( UDP-glucuronosyltransferase, UGT) is a microsomal glycosyltransferase () that catalyzes the transfer of the glucuronic acid component of UDP-glucuronic acid to a small hydrophobic molecule. This is a glucuronidation reaction. ''Alternative names:'' *glucuronyltransferase *UDP-glucuronyl transferase *UDP-GT Function Glucuronosyltransferases are responsible for the process of glucuronidation, a major part of phase II metabolism. Arguably the most important of the Phase II (conjugative) enzymes, UGTs have been the subject of increasing scientific inquiry since the mid-to-late 1990s. The reaction catalyzed by the UGT enzyme involves the addition of a glucuronic acid moiety to xenobiotics and is the most important pathway for the human body's elimination of the most frequently prescribed drugs. It is also the major pathway for foreign chemical (dietary, environmental, pharmaceutical) removal for most drugs, dietary substances, toxins ...
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