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Alfred Tissières
Alfred Tissières (October 14, 1917 – June 7, 2003) was a Swiss molecular biologist, a pioneer in highlighting the role of ribosomes in protein biosynthesis and the initiator of studies on heat shock proteins synthesized by cells subjected to stress. He shared the Marcel Benoist Prize with Edouard Kellenberger in 1966. Early life and education Tissières was born on October 14, 1917 in Martigny. He comes from the neighboring town of Orsières. After studying medicine in Lausanne, where he obtained a doctorate in 1946, Tissières left to do a PhD in England at Cambridge, at the Molteno Institute for Research in Parasitology in the laboratory of David Keilin. Professional and scientific career After studying medicine in Lausanne, where he obtained a doctorate in 1946, Alfred Tissières left to do a PhD in England at Cambridge, at the Molteno Institute for Research in Parasitology in the laboratory of David Keilin. From 1951 to 1952, he carried out a postdoctoral int ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Molecular Biologist
Molecular biology is the branch of biology that seeks to understand the molecular basis of biological activity in and between cells, including biomolecular synthesis, modification, mechanisms, and interactions. The study of chemical and physical structure of biological macromolecules is known as molecular biology. Molecular biology was first described as an approach focused on the underpinnings of biological phenomena - uncovering the structures of biological molecules as well as their interactions, and how these interactions explain observations of classical biology. In 1945 the term molecular biology was used by physicist William Astbury. In 1953 Francis Crick, James Watson, Rosalind Franklin, and colleagues, working at Medical Research Council unit, Cavendish laboratory, Cambridge (now the MRC Laboratory of Molecular Biology), made a double helix model of DNA which changed the entire research scenario. They proposed the DNA structure based on previous research done by Ro ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Escherichia Coli
''Escherichia coli'' (),Wells, J. C. (2000) Longman Pronunciation Dictionary. Harlow ngland Pearson Education Ltd. also known as ''E. coli'' (), is a Gram-negative, facultative anaerobic, rod-shaped, coliform bacterium of the genus ''Escherichia'' that is commonly found in the lower intestine of warm-blooded organisms. Most ''E. coli'' strains are harmless, but some serotypes ( EPEC, ETEC etc.) can cause serious food poisoning in their hosts, and are occasionally responsible for food contamination incidents that prompt product recalls. Most strains do not cause disease in humans and are part of the normal microbiota of the gut; such strains are harmless or even beneficial to humans (although these strains tend to be less studied than the pathogenic ones). For example, some strains of ''E. coli'' benefit their hosts by producing vitamin K2 or by preventing the colonization of the intestine by pathogenic bacteria. These mutually beneficial relationships between ''E. col ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Täschhorn
The Täschhorn (4,491 m) is a mountain in the Pennine Alps in Switzerland, lying south of the Dom within the Mischabel range. The first ascent of the mountain was by John Llewelyn Davies and J. W. Hayward with guides Stefan and Johann Zumtaugwald and Peter-Josef Summermatter on 30 July 1862. See also *List of Alpine four-thousanders This list tabulates all of the 82 official mountain summits of or more in height in the Alps, as defined by the International Climbing and Mountaineering Federation (UIAA). All are located within France, Italy or Switzerland, and are often refe ... External links The Täschhorn on SummitPost Alpine four-thousanders Mountains of the Alps Mountains of Valais Pennine Alps Mountains of Switzerland Four-thousanders of Switzerland {{Valais-mountain-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
European Molecular Biology Organization
The European Molecular Biology Organization (EMBO) is a professional, non-profit organization of more than 1,800 life scientists. Its goal is to promote research in life science and enable international exchange between scientists. It co-funds courses, workshops and conferences, publishes five scientific journals and supports individual scientists. The organization was founded in 1964 and is a founding member of the Initiative for Science in Europe. the Director of EMBO is Fiona Watt, a stem cell researcher, professor at King's College London and a group leader at the European Molecular Biology Laboratory. Conferences and journals EMBO funds or co-funds over 90 meetings involving more than 11,000 participants every year. EMBO publishes five peer-reviewed scientific journals: ''The EMBO Journal'', ''EMBO Reports'', ''Molecular Systems Biology'', ''EMBO Molecular Medicine'', and ''Life Science Alliance'', History The European Molecular Biology Organization (EMBO) was launched ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Chaperone (protein)
In molecular biology, molecular chaperones are proteins that assist the conformational folding or unfolding of large proteins or macromolecular protein complexes. There are a number of classes of molecular chaperones, all of which function to assist large proteins in proper protein folding during or after synthesis, and after partial denaturation. Chaperones are also involved in the translocation of proteins for proteolysis. The first molecular chaperones discovered were a type of assembly chaperones which assist in the assembly of nucleosomes from folded histones and DNA. One major function of molecular chaperones is to prevent the aggregation of misfolded proteins, thus many chaperone proteins are classified as heat shock proteins, as the tendency for protein aggregation is increased by heat stress. The majority of molecular chaperones do not convey any steric information for protein folding, and instead assist in protein folding by binding to and stabilizing folding interme ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Polytene Chromosomes
Polytene chromosomes are large chromosomes which have thousands of DNA strands. They provide a high level of function in certain tissues such as salivary glands of insects. Polytene chromosomes were first reported by E.G.Balbiani in 1881. Polytene chromosomes are found in dipteran flies: the best understood are those of ''Drosophila'', ''Chironomus'' and '' Rhynchosciara''. They are present in another group of arthropods of the class Collembola, a protozoan group Ciliophora, mammalian trophoblasts and antipodal, and suspensor cells in plants. In insects, they are commonly found in the salivary glands when the cells are not dividing. They are produced when repeated rounds of DNA replication without cell division forms a giant chromosome. Thus polytene chromosomes form when multiple rounds of replication produce many sister chromatids ''which stay fused together''. Polytene chromosomes, at interphase, are seen to have distinct thick and thin banding patterns. These patterns w ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Ferruccio Ritossa
Ferruccio Ritossa (February 26, 1936 – January 9, 2014) was an Italian geneticist best known for his discovery of the heat shock response in the model organism '' Drosophila'' (fruit flies). Early life and education Ritossa was born in the town of Pinguente in Istria in 1936, one of three sons. His father, a butcher, was killed in the foibe killings when Ritossa was a young child. His mother moved the family to Italy and taught school in an orphanage, where her three children were also educated. Ritossa attended the University of Bologna to study agricultural sciences and graduated in 1958. He became interested in genetics, particularly in then-emerging molecular studies of the field, and joined a newly established course in biophysics taught by Adriano Buzzati-Traverso at the University of Pavia, where Buzzati-Traverso had begun to establish '' Drosophila'' research and collections. Buzzati-Traverso founded a laboratory, now the Istituto di Genetica e Biofisica, in Nap ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
University Of Geneva
The University of Geneva (French: ''Université de Genève'') is a public research university located in Geneva, Switzerland. It was founded in 1559 by John Calvin as a theological seminary. It remained focused on theology until the 17th century, when it became a center for enlightenment scholarship. Today, it is the third largest university in Switzerland by number of students. In 1873, it dropped its religious affiliations and became officially secular. In 2009, the University of Geneva celebrated the 450th anniversary of its founding. Almost 40% of the students come from foreign countries. The university holds and actively pursues teaching, research, and community service as its primary objectives. In 2016, it was ranked 53rd worldwide by the Shanghai Academic Ranking of World Universities, 89th by the QS World University Rankings, and 131st in the Times Higher Education World University Ranking. UNIGE is a member of the League of European Research Universities (includi ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Marshall Warren Nirenberg
Marshall Warren Nirenberg (April 10, 1927 – January 15, 2010) was an American biochemist and geneticist. He shared a Nobel Prize in Physiology or Medicine in 1968 with Har Gobind Khorana and Robert W. Holley for "breaking the genetic code" and describing how it operates in protein synthesis. In the same year, together with Har Gobind Khorana, he was awarded the Louisa Gross Horwitz Prize from Columbia University. Biography Nirenberg was born in New York City to a Jewish family, the son of Minerva (Bykowsky) and Harry Edward Nirenberg, a shirtmaker. He developed rheumatic fever as a boy, so the family moved to Orlando, Florida to take advantage of the subtropical climate. He developed an early interest in biology. In 1948 he received his BS degree, and in 1952, a master's degree in zoology from the University of Florida at Gainesville where he was also a member of the Pi Lambda Phi Fraternity.Membership Directory, 2010, Pi Lambda Phi Inc. His dissertation for the Master's ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Harvard
Harvard University is a private Ivy League research university in Cambridge, Massachusetts. Founded in 1636 as Harvard College and named for its first benefactor, the Puritan clergyman John Harvard, it is the oldest institution of higher learning in the United States and one of the most prestigious and highly ranked universities in the world. The university is composed of ten academic faculties plus Harvard Radcliffe Institute. The Faculty of Arts and Sciences offers study in a wide range of undergraduate and graduate academic disciplines, and other faculties offer only graduate degrees, including professional degrees. Harvard has three main campuses: the Cambridge campus centered on Harvard Yard; an adjoining campus immediately across Charles River in the Allston neighborhood of Boston; and the medical campus in Boston's Longwood Medical Area. Harvard's endowment is valued at $50.9 billion, making it the wealthiest academic institution in the world. Endowment inco ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
François Gros
François Gros (; 24 April 1925 – 18 February 2022) was a French biologist and one of the pioneers of cellular biochemistry in France. His scientific career concerned genes and their role in regulating cellular functions. Honorary professor at the Collège de France, member of the Institute of France, he was also director of the Pasteur Institute (1976–1982) and advisor to Prime Ministers Pierre Mauroy and Laurent Fabius (1981–1985). Elected correspondent (1977) then member (1979) of the French Academy of Sciences The French Academy of Sciences (French: ''Académie des sciences'') is a learned society, founded in 1666 by Louis XIV of France, Louis XIV at the suggestion of Jean-Baptiste Colbert, to encourage and protect the spirit of French Scientific me ..., he was permanent secretary from 1991 to 2000. Gros died on 18 February 2022, at the age of 96. [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Jacques Monod
Jacques Lucien Monod (February 9, 1910 – May 31, 1976) was a French biochemist who won the Nobel Prize in Physiology or Medicine in 1965, sharing it with François Jacob and André Lwoff "for their discoveries concerning genetic control of enzyme and virus synthesis".'' Chance and Necessity: An Essay on the Natural Philosophy of Modern Biology'' by Jacques Monod, New York, Alfred A. Knopf, 1971, Monod and Jacob became famous for their work on the '' E. coli'' ''lac'' operon, which encodes proteins necessary for the transport and breakdown of the sugar lactose (lac). From their own work and the work of others, they came up with a model for how the levels of some proteins in a cell are controlled. In their model, the manufacture of proteins, such as the ones encoded within the ''lac'' (lactose) operon, is prevented when a repressor, encoded by a regulatory gene, binds to its operator, a specific site in the DNA sequence that is close to the genes encoding the proteins. (It is ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
