Alfred Fröhlich
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Alfred Fröhlich
Alfred Fröhlich (August 15, 1871 – March 22, 1953) was an Austrian-American pharmacologist and neurologist born in Vienna. Biography Fröhlich was born in Vienna, into a Jewish family.Joseph Meites, ''Pioneers in Neuroendocrinology'', Springer Science & Business Media (2012), p. 115 In 1895 he graduated from the University of Vienna, afterwards remaining at Vienna as an assistant to Carl Nothnagel (1841–1905). In 1905 he became a member of the department of pharmacology at the university, and from 1919 until 1939 he was a full professor of pharmacology and toxicology. Following the Nazi takeover of Austria, Fröhlich emigrated to the United States, where he worked at the May Institute of Medical Research of the Jewish Hospital of Cincinnati. Here he continued his experimental research of the central nervous system. He is remembered for his studies on the effects of the pituitary on the autonomic nervous system. With Otto Loewi (1873–1961), he performed pharmacological ...
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Alfred Frohlich
Alfred may refer to: Arts and entertainment *''Alfred J. Kwak'', Dutch-German-Japanese anime television series *Alfred (Arne opera), ''Alfred'' (Arne opera), a 1740 masque by Thomas Arne *Alfred (Dvořák), ''Alfred'' (Dvořák), an 1870 opera by Antonín Dvořák *"Alfred (Interlude)" and "Alfred (Outro)", songs by Eminem from the 2020 album ''Music to Be Murdered By'' Business and organisations * Alfred, a radio station in Shaftesbury, England *Alfred Music, an American music publisher *Alfred University, New York, U.S. *The Alfred Hospital, a hospital in Melbourne, Australia People * Alfred (name) includes a list of people and fictional characters called Alfred * Alfred the Great (848/49 – 899), or Alfred I, a king of the West Saxons and of the Anglo-Saxons Places Antarctica * Mount Alfred (Antarctica) Australia * Alfredtown, New South Wales * County of Alfred, South Australia Canada * Alfred and Plantagenet, Ontario * Alfred Island, Nunavut * Mount Alfred, British Colu ...
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Charles Scott Sherrington
Sir Charles Scott Sherrington (27 November 1857 – 4 March 1952) was an eminent English neurophysiologist. His experimental research established many aspects of contemporary neuroscience, including the concept of the spinal reflex as a system involving connected neurons (the "neuron doctrine"), and the ways in which signal transmission between neurons can be potentiated or depotentiated. Sherrington himself coined the word "synapse" to define the connection between two neurons. His book ''The Integrative Action of the Nervous System'' (1906) is a synthesis of this work, in recognition of which he was awarded the Nobel Prize in Physiology or Medicine in 1932 (along with Edgar Adrian). In addition to his work in physiology, Sherrington did research in histology, bacteriology, and pathology. He was president of the Royal Society in the early 1920s. Biography Early years and education Official biographies claim Charles Scott Sherrington was born in Islington, London, England, o ...
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Pharmacology
Pharmacology is a branch of medicine, biology and pharmaceutical sciences concerned with drug or medication action, where a drug may be defined as any artificial, natural, or endogenous (from within the body) molecule which exerts a biochemical or physiological effect on the cell, tissue, organ, or organism (sometimes the word ''pharmacon'' is used as a term to encompass these endogenous and exogenous bioactive species). More specifically, it is the study of the interactions that occur between a living organism and chemicals that affect normal or abnormal biochemical function. If substances have medicinal properties, they are considered pharmaceuticals. The field encompasses drug composition and properties,functions,sources,synthesis and drug design, molecular and cellular mechanisms, organ/systems mechanisms, signal transduction/cellular communication, molecular diagnostics, interactions, chemical biology, therapy, and medical applications and antipathogenic capabilities. ...
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Acromegaly
Acromegaly is a disorder that results from excess growth hormone (GH) after the growth plates have closed. The initial symptom is typically enlargement of the hands and feet. There may also be an enlargement of the forehead, jaw, and nose. Other symptoms may include joint pain, thicker skin, deepening of the voice, headaches, and problems with vision. Complications of the disease may include type 2 diabetes, sleep apnea, and high blood pressure. Acromegaly is usually caused by the pituitary gland producing excess growth hormone. In more than 95% of cases the excess production is due to a benign tumor, known as a pituitary adenoma. The condition is not inherited from a person's parents. Acromegaly is rarely due to a tumor in another part of the body. Diagnosis is by measuring growth hormone after a person has consumed a glucose solution, or by measuring insulin-like growth factor I in the blood. After diagnosis, medical imaging of the pituitary is carried out to determine if an ...
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Hypophysis Cerebri
In vertebrate anatomy, the pituitary gland, or hypophysis, is an endocrine gland, about the size of a chickpea and weighing, on average, in humans. It is a protrusion off the bottom of the hypothalamus at the base of the brain. The hypophysis rests upon the hypophyseal fossa of the sphenoid bone in the center of the middle cranial fossa and is surrounded by a small bony cavity (sella turcica) covered by a Dura mater, dural fold (diaphragma sellae). The anterior pituitary (or adenohypophysis) is a lobe of the gland that regulates several physiological processes including stress, growth, reproduction, and lactation. The intermediate lobe synthesizes and secretes melanocyte-stimulating hormone. The posterior pituitary (or neurohypophysis) is a lobe of the gland that is functionally connected to the hypothalamus by the median eminence via a small tube called the pituitary stalk (also called the infundibular stalk or the infundibulum). Hormones secreted from the pituitary gla ...
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Joseph Babinski
Joseph Jules François Félix Babinski ( pl, Józef Julian Franciszek Feliks Babiński; 17 November 1857 – 29 October 1932) was a French-Polish professor of neurology. He is best known for his 1896 description of the Babinski sign, a pathological plantar reflex indicative of corticospinal tract damage. Life Born in Paris, Babinski was the son of a Polish military officer, Aleksander Babiński (1824–1889), and his wife Henryeta Weren Babińska (1819–1897),Joseph Babinski
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who in 1848 fled for because of a Tsarist reign of terror instigated to stall Polish attempts at achieving independence an ...
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Babinski-Fröhlich Syndrome
Adiposogenital dystrophy is a condition that may be caused by tertiary hypogonadism originating from decreased levels in GnRH. Low levels of GnRH has been associated with defects of the feeding centers of the hypothalamus, leading to an increased consumption of food and thus caloric intake. Presentation It is characterized by: * Obesity * Growth delays and delayed sexual development, atrophy or hypoplasia of the gonads, and altered secondary sex characteristics, * Headaches * Problems with vision * polyuria, polydipsia. It is usually associated with tumors of the hypothalamus, causing increased appetite and depressed secretion of gonadotropin. It seems to affect males mostly.Many overweight children may appear to have the disorder because of the concurrence of obesity and retarded sexual development; these children have no endocrine disturbances, however, and they mature normally after delayed puberty Puberty is the process of physical changes through which a child's body ...
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Fröhlich's Syndrome
Adiposogenital dystrophy is a condition that may be caused by tertiary hypogonadism originating from decreased levels in GnRH. Low levels of GnRH has been associated with defects of the feeding centers of the hypothalamus, leading to an increased consumption of food and thus caloric intake. Presentation It is characterized by: * Obesity * Growth delays and delayed sexual development, atrophy or hypoplasia of the gonads, and altered secondary sex characteristics, * Headaches * Problems with vision * polyuria, polydipsia. It is usually associated with tumors of the hypothalamus, causing increased appetite and depressed secretion of gonadotropin. It seems to affect males mostly.Many overweight children may appear to have the disorder because of the concurrence of obesity and retarded sexual development; these children have no endocrine disturbances, however, and they mature normally after delayed puberty Puberty is the process of physical changes through which a child's body ...
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Tumor
A neoplasm () is a type of abnormal and excessive growth of tissue. The process that occurs to form or produce a neoplasm is called neoplasia. The growth of a neoplasm is uncoordinated with that of the normal surrounding tissue, and persists in growing abnormally, even if the original trigger is removed. This abnormal growth usually forms a mass, when it may be called a tumor. ICD-10 classifies neoplasms into four main groups: benign neoplasms, in situ neoplasms, malignant neoplasms, and neoplasms of uncertain or unknown behavior. Malignant neoplasms are also simply known as cancers and are the focus of oncology. Prior to the abnormal growth of tissue, as neoplasia, cells often undergo an abnormal pattern of growth, such as metaplasia or dysplasia. However, metaplasia or dysplasia does not always progress to neoplasia and can occur in other conditions as well. The word is from Ancient Greek 'new' and 'formation, creation'. Types A neoplasm can be benign, potentially m ...
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Obesity
Obesity is a medical condition, sometimes considered a disease, in which excess body fat has accumulated to such an extent that it may negatively affect health. People are classified as obese when their body mass index (BMI)—a person's weight divided by the square of the person's height—is over ; the range is defined as overweight. Some East Asian countries use lower values to calculate obesity. Obesity is a major cause of disability and is correlated with various diseases and conditions, particularly cardiovascular diseases, type 2 diabetes, obstructive sleep apnea, certain types of cancer, and osteoarthritis. Obesity has individual, socioeconomic, and environmental causes. Some known causes are diet, physical activity, automation, urbanization, genetic susceptibility, medications, mental disorders, economic policies, endocrine disorders, and exposure to endocrine-disrupting chemicals. While a majority of obese individuals at any given time are attempting to ...
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Dystrophia Adiposogenitalis
Adiposogenital dystrophy is a condition that may be caused by tertiary hypogonadism originating from decreased levels in GnRH. Low levels of GnRH has been associated with defects of the feeding centers of the hypothalamus, leading to an increased consumption of food and thus caloric intake. Presentation It is characterized by: * Obesity * Growth delays and delayed sexual development, atrophy or hypoplasia of the gonads, and altered secondary sex characteristics, * Headaches * Problems with vision * polyuria, polydipsia. It is usually associated with tumors of the hypothalamus, causing increased appetite and depressed secretion of gonadotropin. It seems to affect males mostly.Many overweight children may appear to have the disorder because of the concurrence of obesity and retarded sexual development; these children have no endocrine disturbances, however, and they mature normally after delayed puberty Puberty is the process of physical changes through which a child's body ...
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Woods Hole, Massachusetts
Woods Hole is a census-designated place in the town of Falmouth in Barnstable County, Massachusetts, United States. It lies at the extreme southwest corner of Cape Cod, near Martha's Vineyard and the Elizabeth Islands. The population was 781 at the 2010 census. It is the site of several marine science institutions, including Woods Hole Oceanographic Institution, the Marine Biological Laboratory, the Woodwell Climate Research Center, NOAA's Northeast Fisheries Science Center (which started the Woods Hole scientific community in 1871), the Woods Hole Science Aquarium, a USGS coastal and marine geology center, and the home campus of the Sea Education Association. And the headquarter of the Climate Foundation. It is also the site of United States Coast Guard Sector Southeastern New England (formerly USCG Group Woods Hole), the Nobska Light lighthouse, and the terminus of the Steamship Authority ferry route between Cape Cod and the island of Martha's Vineyard. History Histor ...
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