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Alexander Glenny
Alexander Thomas Glenny (18 September 1882 – 5 October 1965), was a British immunologist known particularly for his work on the prevention of diphtheria. He was born in Camberwell, London, England, educated at Alleyn's School, Dulwich and awarded a B.Sc. by the University of London in 1905. In 1899 he started working for the Wellcome Physiological Research Laboratories, then in Central London, becoming head of the immunology department in 1906. He worked on immunizations and antitoxins against diseases, including tetanus and diphtheria, and, later, chemical weapons. His scientific work focused on the mechanisms of antibody production and the prevention of diphtheria. In 1921 he and H. J. Südmersen discovered the primary and secondary immune response. In the same paper they also briefly described the properties of diphtheria toxoid, which had been discovered by Glenny in 1904, apparently by accident. In 1925-6 he developed alum-precipitated diphtheria toxoid. He was electe ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Camberwell
Camberwell () is a district of South London, England, in the London Borough of Southwark, southeast of Charing Cross. Camberwell was first a village associated with the church of St Giles and a common of which Goose Green is a remnant. This early parish included the neighbouring hamlets of Peckham, Dulwich, Nunhead, and part of Herne Hill (the rest of Herne Hill was in the parish of Lambeth). Until 1889, it was part of the county of Surrey. In 1900 the original parish became the Metropolitan Borough of Camberwell. In 1965, most of the Borough of Camberwell was merged into the London Borough of Southwark.Southwark London Borough Council â€Community guide for Camberwell To the west, part of both West Dulwich and Herne Hill come under the London Borough of Lambeth. The place now known as Camberwell covers a much smaller area than the ancient parish, and it is bound on the north by Walworth; on the south by East Dulwich and Herne Hill; to the west by Kennington; and on the east ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Immunology
Immunology is a branch of medicineImmunology for Medical Students, Roderick Nairn, Matthew Helbert, Mosby, 2007 and biology that covers the medical study of immune systems in humans, animals, plants and sapient species. In such we can see there is a difference of human immunology and comparative immunology in veterinary medicine and animal biosciences. Immunology measures, uses charts and differentiate in context in medicine the studies of immunity on cell and molecular level, and the immune system as part of the physiological level as its functioning is of major importance. In the different states of both health, occurring symptoms and diseases; the functioning of the immune system and immunological responses such as autoimmune diseases, allergic hypersensitivities, or in some cases malfunctioning of immune system as for example in immunological disorders or in immune deficiency, and the specific transplant rejection) Immunology has applications in numerous disciplines of ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Diphtheria
Diphtheria is an infection caused by the bacterium '' Corynebacterium diphtheriae''. Most infections are asymptomatic or have a mild clinical course, but in some outbreaks more than 10% of those diagnosed with the disease may die. Signs and symptoms may vary from mild to severe and usually start two to five days after exposure. Symptoms often come on fairly gradually, beginning with a sore throat and fever. In severe cases, a grey or white patch develops in the throat. This can block the airway and create a barking cough as in croup. The neck may swell in part due to enlarged lymph nodes. A form of diphtheria which involves the skin, eyes or genitals also exists. Complications may include myocarditis, inflammation of nerves, kidney problems, and bleeding problems due to low levels of platelets. Myocarditis may result in an abnormal heart rate and inflammation of the nerves may result in paralysis. Diphtheria is usually spread between people by direct contact or through th ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Wellcome Research Laboratories
Wellcome Research Laboratories was a site in Beckenham, south-east London, that was a main research centre for pharmaceuticals. Until 1965, this laboratory site was situated in Kent. History In 1894 Henry Wellcome set up a laboratory in central London to investigate a treatment for diphtheria. In 1898 it moved to Brockwell Hall in Herne Hill (now in Lambeth). In 1919 Henry Wellcome bought a 105-acre site in Beckenham, Kent, which cost £32,000. The site had belonged to the Langley family since 1350. Langley Court had been built in 1886 by James Bucknall, who lived in the house with his family until 1914. It was named the Wellcome Research Laboratories in 1946 after the Wellcome Chemical Research Laboratories moved to the site. The Wellcome Trust had been set up in 1936, after the death in that year of Sir Henry Wellcome. They have developed the antibiotic trimethoprim. Awards In April 1990, the site won the Queen's Award for Export and Technological Achievement for their Retrov ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Tetanus
Tetanus, also known as lockjaw, is a bacterial infection caused by ''Clostridium tetani'', and is characterized by muscle spasms. In the most common type, the spasms begin in the jaw and then progress to the rest of the body. Each spasm usually lasts a few minutes. Spasms occur frequently for three to four weeks. Some spasms may be severe enough to fracture bones. Other symptoms of tetanus may include fever, sweating, headache, trouble swallowing, high blood pressure, and a fast heart rate. Onset of symptoms is typically three to twenty-one days following infection. Recovery may take months. About ten percent of cases prove to be fatal. ''C. tetani'' is commonly found in soil, saliva, dust, and manure. The bacteria generally enter through a break in the skin such as a cut or puncture wound by a contaminated object. They produce toxins that interfere with normal muscle contractions. Diagnosis is based on the presenting signs and symptoms. The disease does not spread between pe ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Chemical Weapon
A chemical weapon (CW) is a specialized munition that uses chemicals formulated to inflict death or harm on humans. According to the Organisation for the Prohibition of Chemical Weapons (OPCW), this can be any chemical compound intended as a weapon "or its precursor that can cause death, injury, temporary incapacitation or sensory irritation through its chemical action. Munitions or other delivery devices designed to deliver chemical weapons, whether filled or unfilled, are also considered weapons themselves." Chemical weapons are classified as weapons of mass destruction (WMD), though they are distinct from nuclear weapons, biological weapons, and radiological weapons. All may be used in warfare and are known by the military acronym NBC (for nuclear, biological, and chemical warfare). Weapons of mass destruction are distinct from conventional weapons, which are primarily effective due to their explosive, kinetic, or incendiary potential. Chemical weapons can be widely dispe ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Antibody
An antibody (Ab), also known as an immunoglobulin (Ig), is a large, Y-shaped protein used by the immune system to identify and neutralize foreign objects such as pathogenic bacteria and viruses. The antibody recognizes a unique molecule of the pathogen, called an antigen. Each tip of the "Y" of an antibody contains a paratope (analogous to a lock) that is specific for one particular epitope (analogous to a key) on an antigen, allowing these two structures to bind together with precision. Using this binding mechanism, an antibody can ''tag'' a microbe or an infected cell for attack by other parts of the immune system, or can neutralize it directly (for example, by blocking a part of a virus that is essential for its invasion). To allow the immune system to recognize millions of different antigens, the antigen-binding sites at both tips of the antibody come in an equally wide variety. In contrast, the remainder of the antibody is relatively constant. It only occurs in a few varia ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Toxoid
A toxoid is an inactivated toxin (usually an exotoxin) whose toxicity has been suppressed either by chemical (formalin) or heat treatment, while other properties, typically immunogenicity, are maintained. Toxins are secreted by bacteria, whereas toxoids are altered form of toxins; toxoids are ''not'' secreted by bacteria. Thus, when used during vaccination, an immune response is mounted and immunological memory is formed against the molecular markers of the toxoid without resulting in toxin-induced illness. Such a preparation is also known as an anatoxin. There are toxoids for prevention of diphtheria, tetanus and botulism. Toxoids are used as vaccines because they induce an immune response to the original toxin or increase the response to another antigen since the toxoid markers and toxin markers are preserved. For example, the tetanus toxoid is derived from the tetanospasmin produced by ''Clostridium tetani''. The latter causes tetanus and is vaccinated against by the DTaP vac ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Alum
An alum () is a type of chemical compound, usually a hydrated double salt, double sulfate salt (chemistry), salt of aluminium with the general chemical formula, formula , where is a valence (chemistry), monovalent cation such as potassium or ammonium. By itself, "alum" often refers to potassium alum, with the formula . Other alums are named after the monovalent ion, such as sodium alum and ammonium alum. The name "alum" is also used, more generally, for salts with the same formula and structure, except that aluminium is replaced by another valence (chemistry), trivalent metal ion like chromium#Chromium(III), chromium, and/or sulfur is replaced by another chalcogen like selenium. The most common of these analogs is chrome alum . In most industries, the name "alum" (or "papermaker's alum") is used to refer to aluminium sulfate, , which is used for most industrial flocculation (the variable is an integer whose size depends on the amount of water absorbed into the alum). In medic ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Fellow Of The Royal Society
Fellowship of the Royal Society (FRS, ForMemRS and HonFRS) is an award granted by the judges of the Royal Society of London to individuals who have made a "substantial contribution to the improvement of natural science, natural knowledge, including mathematics, engineering science, and medical science". Fellow, Fellowship of the Society, the oldest known scientific academy in continuous existence, is a significant honour. It has been awarded to many eminent scientists throughout history, including Isaac Newton (1672), Michael Faraday (1824), Charles Darwin (1839), Ernest Rutherford (1903), Srinivasa Ramanujan (1918), Albert Einstein (1921), Paul Dirac (1930), Winston Churchill (1941), Subrahmanyan Chandrasekhar (1944), Dorothy Hodgkin (1947), Alan Turing (1951), Lise Meitner (1955) and Francis Crick (1959). More recently, fellowship has been awarded to Stephen Hawking (1974), David Attenborough (1983), Tim Hunt (1991), Elizabeth Blackburn (1992), Tim Berners-Lee (2001), Venki R ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Edward Jenner Medal
The Edward Jenner Medal is awarded occasionally by the Royal Society of Medicine to individuals who have undertaken distinguished work in epidemiological research. The award was founded in 1896 by the Epidemiological Society of London (1850–1907) to commemorate the centenary of Edward Jenner’s discovery of a means of smallpox vaccination. The Epidemiological Society became a founder member of the Royal Society of Medicine in 1907. The medal was designed in Bronze by Allan Wyon. It features Jenner’s face on one aspect and the symbol of the Epidemiological Society, the Earth, on the reverse. The medal was re-cast following the evolution of the Society into the Section of Epidemiology at the RSM in 1907. Photographs of the medal may be found in ''The History of the Royal Society of Medicine'' published in 2001. It was first awarded to Sir William Henry Power who was the then Medical Officer for London and had formulated the theory of aerial conveyance of smallpox and chaired ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Royal Society Of Medicine
The Royal Society of Medicine (RSM) is a medical society in the United Kingdom, headquartered in London. History The Society was established in 1805 as Medical and Chirurgical Society of London, meeting in two rooms in barristers’ chambers at Gray's Inn and then moving to Lincoln's Inn Fields where it stayed for 25 years. In 1834 the Society moved to Berners Street and was granted a Royal Charter by King William IV. In 1889 under the leadership of Sir John MacAlister, a Building Committee chaired by Timothy Holmes supervised the move of the quarters of the Society from Berners Street to 20 Hanover Square. In 1905 an eleven-member committee headed by Sir Richard Douglas Powell organised the celebration of the Society's centenary. Two years later the Royal Medical and Chirurgical Society of London came together with seventeen specialist medical societies and, with a supplementary Royal Charter granted by Edward VII, became the Royal Society of Medicine. In 1910 the Society ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
