Alexander Cools
   HOME
*





Alexander Cools
Alexander ("Lex") Rudolf Cools (1941 in The Hague – 7 September 2013 in Nijmegen) was a Dutch behavioral pharmacologist. He obtained his Ph.D. under the supervision of Jacques van Rossum and Jo Vossen in 1973 at the Radboud University Nijmegen, where he was a professor from 1985 until his retirement in 2006. In 2014, a special issue of the scientific journal ''Behavioural Pharmacology'' was dedicated to his memory. Cools was one of the founders of the European Behavioural Pharmacology Society and its second president. In 2003 he received that society's Distinguished Achievement Award. In 1976, Cools was the first to propose the existence of different types of dopamine receptors, an essentially correct claim that initially was generally dismissed. Besides his work on dopamine, Cools is mostly known for his work on the basal ganglia and the dorsal and ventral striatum The striatum, or corpus striatum (also called the striate nucleus), is a nucleus (a cluster of neurons) ...
[...More Info...]      
[...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]  


picture info

The Hague
The Hague ( ; nl, Den Haag or ) is a city and municipality of the Netherlands, situated on the west coast facing the North Sea. The Hague is the country's administrative centre and its seat of government, and while the official capital of the Netherlands is Amsterdam, The Hague has been described as the country's de facto capital. The Hague is also the capital of the province of South Holland, and the city hosts both the International Court of Justice and the International Criminal Court. With a population of over half a million, it is the third-largest city in the Netherlands, after Amsterdam and Rotterdam. The Hague is the core municipality of the Greater The Hague urban area, which comprises the city itself and its suburban municipalities, containing over 800,000 people, making it the third-largest urban area in the Netherlands, again after the urban areas of Amsterdam and Rotterdam. The Rotterdam–The Hague metropolitan area, with a population of approximately 2.6&n ...
[...More Info...]      
[...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]  


Behavioural Pharmacology (journal)
''Behavioural Pharmacology'' is a peer-reviewed scientific journal covering the effects of biological active compounds on behaviour in animals, including humans. It is published by Lippincott Williams & Wilkins and the current editor-in-chief is professor Bart Ellenbroek (Victoria University of Wellington). Abstracting and indexing The journal is abstracted and indexed in: According to the ''Journal Citation Reports'', the journal has a 2014 impact factor The impact factor (IF) or journal impact factor (JIF) of an academic journal is a scientometric index calculated by Clarivate that reflects the yearly mean number of citations of articles published in the last two years in a given journal, as i ... of 2.148. References External links * Lippincott Williams & Wilkins academic journals English-language journals Academic journals established in 1989 Pharmacology journals Neuroscience journals {{pharma-journal-stub ...
[...More Info...]      
[...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]  


picture info

People In Health Professions From The Hague
A person ( : people) is a being that has certain capacities or attributes such as reason, morality, consciousness or self-consciousness, and being a part of a culturally established form of social relations such as kinship, ownership of property, or legal responsibility. The defining features of personhood and, consequently, what makes a person count as a person, differ widely among cultures and contexts. In addition to the question of personhood, of what makes a being count as a person to begin with, there are further questions about personal identity and self: both about what makes any particular person that particular person instead of another, and about what makes a person at one time the same person as they were or will be at another time despite any intervening changes. The plural form "people" is often used to refer to an entire nation or ethnic group (as in "a people"), and this was the original meaning of the word; it subsequently acquired its use as a plural form of per ...
[...More Info...]      
[...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]  


Dutch Neuroscientists
Dutch commonly refers to: * Something of, from, or related to the Netherlands * Dutch people () * Dutch language () Dutch may also refer to: Places * Dutch, West Virginia, a community in the United States * Pennsylvania Dutch Country People Ethnic groups * Germanic peoples, the original meaning of the term ''Dutch'' in English ** Pennsylvania Dutch, a group of early Germanic immigrants to Pennsylvania *Dutch people, the Germanic group native to the Netherlands Specific people * Dutch (nickname), a list of people * Johnny Dutch (born 1989), American hurdler * Dutch Schultz (1902–1935), American mobster born Arthur Simon Flegenheimer * Dutch Mantel, ring name of American retired professional wrestler Wayne Maurice Keown (born 1949) * Dutch Savage, ring name of professional wrestler and promoter Frank Stewart (1935–2013) Arts, entertainment, and media Fictional characters * Dutch (''Black Lagoon''), an African-American character from the Japanese manga and anime ''Blac ...
[...More Info...]      
[...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]  


picture info

Academic Staff Of Radboud University Nijmegen
An academy (Attic Greek: Ἀκαδήμεια; Koine Greek Ἀκαδημία) is an institution of secondary or tertiary higher learning (and generally also research or honorary membership). The name traces back to Plato's school of philosophy, founded approximately 385 BC at Akademia, a sanctuary of Athena, the goddess of wisdom and skill, north of Athens, Greece. Etymology The word comes from the ''Academy'' in ancient Greece, which derives from the Athenian hero, ''Akademos''. Outside the city walls of Athens, the gymnasium was made famous by Plato as a center of learning. The sacred space, dedicated to the goddess of wisdom, Athena, had formerly been an olive grove, hence the expression "the groves of Academe". In these gardens, the philosopher Plato conversed with followers. Plato developed his sessions into a method of teaching philosophy and in 387 BC, established what is known today as the Old Academy. By extension, ''academia'' has come to mean the accumulation, dev ...
[...More Info...]      
[...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]  


Radboud University Nijmegen Alumni
Radbod, Radbot, Ratbod, Ratpot, Redbod, Redbad, Radboud, Rapoto, or sometimes just Boddo, is a Germanic masculine given name that may refer to: *Redbad, King of the Frisians (died 719) *Radbod (prefect) (833–54), Frankish prefect *Ratbod (archbishop of Trier) (died 915) *Radboud of Utrecht (died 917), bishop *Radbot, Count of Habsburg (died 1045) *Rabodo (died 1119) * ''Redbad'' (film), 2018 Dutch film Radboud may also refer to *Radboud University Nijmegen (formerly Catholic University Nijmegen), called after Saint Radboud *Radboud University Nijmegen Medical Centre The Radboud University Medical Center (Dutch: ''Radboudumc''), is the teaching hospital affiliated with the Radboud University Nijmegen, in the city of Nijmegen in the eastern-central part of the Netherlands ) , anthem = ( en, "William of N ...
{{disambig ...
[...More Info...]      
[...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]  


picture info

Striatum
The striatum, or corpus striatum (also called the striate nucleus), is a nucleus (a cluster of neurons) in the subcortical basal ganglia of the forebrain. The striatum is a critical component of the motor and reward systems; receives glutamatergic and dopaminergic inputs from different sources; and serves as the primary input to the rest of the basal ganglia. Functionally, the striatum coordinates multiple aspects of cognition, including both motor and action planning, decision-making, motivation, reinforcement, and reward perception. The striatum is made up of the caudate nucleus and the lentiform nucleus. The lentiform nucleus is made up of the larger putamen, and the smaller globus pallidus. Strictly speaking the globus pallidus is part of the striatum. It is common practice, however, to implicitly exclude the globus pallidus when referring to striatal structures. In primates, the striatum is divided into a ventral striatum, and a dorsal striatum, subdivisions that are ...
[...More Info...]      
[...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]  




Psychopharmacologia
''Psychopharmacology'' is an international, peer-reviewed scientific journal covering the field of psychopharmacology. It is the official journal of the European Behavioural Pharmacology Society and is published by Springer Science+Business Media. The current Coordinating editors of the journal are Trevor Robbins, Christelle Baunez, and Patricia Janak Patricia Janak is a Bloomberg Distinguished Professor at Johns Hopkins University who studies the biological basis of behavior through associative learning. Janak applies this research to pathological behaviors, such as addiction and posttraumati .... References External links * Pharmacology journals Neuroscience journals English-language journals {{pharma-journal-stub ...
[...More Info...]      
[...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]  


Dopamine Receptor
Dopamine receptors are a class of G protein-coupled receptors that are prominent in the vertebrate central nervous system (CNS). Dopamine receptors activate different effectors through not only G-protein coupling, but also signaling through different protein (dopamine receptor-interacting proteins) interactions. The neurotransmitter dopamine is the primary endogenous ligand for dopamine receptors. Dopamine receptors are implicated in many neurological processes, including motivational and incentive salience, cognition, memory, learning, and fine motor control, as well as modulation of neuroendocrine signaling. Abnormal dopamine receptor signaling and dopaminergic nerve function is implicated in several neuropsychiatric disorders. Thus, dopamine receptors are common neurologic drug targets; antipsychotics are often dopamine receptor antagonists while psychostimulants are typically indirect agonists of dopamine receptors. Subtypes The existence of multiple types of receptors for ...
[...More Info...]      
[...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]  


European Behavioural Pharmacology Society
European, or Europeans, or Europeneans, may refer to: In general * ''European'', an adjective referring to something of, from, or related to Europe ** Ethnic groups in Europe ** Demographics of Europe ** European cuisine, the cuisines of Europe and other Western countries * ''European'', an adjective referring to something of, from, or related to the European Union ** Citizenship of the European Union ** Demographics of the European Union In publishing * ''The European'' (1953 magazine), a far-right cultural and political magazine published 1953–1959 * ''The European'' (newspaper), a British weekly newspaper published 1990–1998 * ''The European'' (2009 magazine), a German magazine first published in September 2009 *''The European Magazine'', a magazine published in London 1782–1826 *''The New European'', a British weekly pop-up newspaper first published in July 2016 Other uses * * Europeans (band), a British post-punk group, from Bristol See also * * * Europe (disambi ...
[...More Info...]      
[...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]  


picture info

Scientific Journal
In academic publishing, a scientific journal is a periodical publication intended to further the progress of science, usually by reporting new research. Content Articles in scientific journals are mostly written by active scientists such as students, researchers, and professors instead of professional journalists. There are thousands of scientific journals in publication, and many more have been published at various points in the past (see list of scientific journals). Most journals are highly specialized, although some of the oldest journals such as ''Nature'' publish articles and scientific papers across a wide range of scientific fields. Scientific journals contain articles that have been peer reviewed, in an attempt to ensure that articles meet the journal's standards of quality and scientific validity. Although scientific journals are superficially similar to professional magazines, they are actually quite different. Issues of a scientific journal are rarely read casuall ...
[...More Info...]      
[...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]  


Netherlands
) , anthem = ( en, "William of Nassau") , image_map = , map_caption = , subdivision_type = Sovereign state , subdivision_name = Kingdom of the Netherlands , established_title = Before independence , established_date = Spanish Netherlands , established_title2 = Act of Abjuration , established_date2 = 26 July 1581 , established_title3 = Peace of Münster , established_date3 = 30 January 1648 , established_title4 = Kingdom established , established_date4 = 16 March 1815 , established_title5 = Liberation Day (Netherlands), Liberation Day , established_date5 = 5 May 1945 , established_title6 = Charter for the Kingdom of the Netherlands, Kingdom Charter , established_date6 = 15 December 1954 , established_title7 = Dissolution of the Netherlands Antilles, Caribbean reorganisation , established_date7 = 10 October 2010 , official_languages = Dutch language, Dutch , languages_type = Regional languages , languages_sub = yes , languages = , languages2_type = Reco ...
[...More Info...]      
[...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]