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Alan Lambowitz
Alan Lambowitz is a professor for the University of Texas at Austin in Molecular Biosciences and Oncology and has been instrumental in many bio-molecular processes and concepts, such as intron splicing and mitochondrial ribosomal assembly. Education Alan Lambowitz was born in Brooklyn, New York on December 24, 1947. Growing up he attended Stuyvesant High School, a school specialized in science. Following high school, he attended Brooklyn College for his undergraduate degree in Chemistry. Upon completing this degree in 1968, Lambowitz promptly began graduate school at Yale where he continued his love for science in the laboratory. He received a Ph.D. from Yale and then decided to move his work to the Johnson Research Foundation at the University of Pennsylvania. Career During his postdoctoral work, Lambowitz investigated a common mechanism of oxidative phosphorylation and discovered that the mechanism was incorrect. Lambowitz once again moved in 1973 to Rockefeller University. ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Alan
Alan may refer to: People *Alan (surname), an English and Turkish surname * Alan (given name), an English given name **List of people with given name Alan ''Following are people commonly referred to solely by "Alan" or by a homonymous name.'' *Alan (Chinese singer) (born 1987), female Chinese singer of Tibetan ethnicity, active in both China and Japan *Alan (Mexican singer) (born 1973), Mexican singer and actor * Alan (wrestler) (born 1975), a.k.a. Gato Eveready, who wrestles in Asistencia Asesoría y Administración *Alan (footballer, born 1979) (Alan Osório da Costa Silva), Brazilian footballer *Alan (footballer, born 1998) (Alan Cardoso de Andrade), Brazilian footballer *Alan I, King of Brittany (died 907), "the Great" *Alan II, Duke of Brittany (c. 900–952) * Alan III, Duke of Brittany(997–1040) *Alan IV, Duke of Brittany (c. 1063–1119), a.k.a. Alan Fergant ("the Younger" in Breton language) *Alan of Tewkesbury, 12th century abbott *Alan of Lynn (c. 1348–1423), 15th c ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Ohio State University
The Ohio State University, commonly called Ohio State or OSU, is a public land-grant research university in Columbus, Ohio. A member of the University System of Ohio, it has been ranked by major institutional rankings among the best public universities in the United States. Founded in 1870 as the state's land-grant university and the ninth university in Ohio with the Morrill Act of 1862, Ohio State was originally known as the Ohio Agricultural and Mechanical College and focused on various agricultural and mechanical disciplines, but it developed into a comprehensive university under the direction of then-Governor and later U.S. president Rutherford B. Hayes, and in 1878, the Ohio General Assembly passed a law changing the name to "the Ohio State University" and broadening the scope of the university. Admission standards tightened and became greatly more selective throughout the 2000s and 2010s. Ohio State's political science department and faculty have greatly contri ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Lineage (evolution)
An evolutionary lineage is a temporal series of populations, organisms, cells, or genes connected by a continuous line of descent from ancestor to descendant.The Oxford English Dictionary defines biological lineage as "a sequence of species each of which is considered to have evolved from its predecessorOED definition of lineage/ref> Lineages are subsets of the evolutionary tree of life. Lineages are often determined by the techniques of molecular systematics. Phylogenetic representation of lineages 299x299px, A rooted tree of life into three ancient monophyletic lineages: bacteria, archaea, and eukaryotes">archaea.html" ;"title="bacteria, archaea">bacteria, archaea, and eukaryotes based on rRNA genes Lineages are typically visualized as subsets of a phylogenetic tree. A lineage is a single line of descent or linear chain within the tree, while a clade is a (usually branched) monophyletic group, containing a single ancestor and all its descendants. Phylogenetic trees are typica ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
RNA-Seq
RNA-Seq (named as an abbreviation of RNA sequencing) is a sequencing technique which uses next-generation sequencing (NGS) to reveal the presence and quantity of RNA in a biological sample at a given moment, analyzing the continuously changing cellular transcriptome. Specifically, RNA-Seq facilitates the ability to look at alternative gene spliced transcripts, post-transcriptional modifications, gene fusion, mutations/SNPs and changes in gene expression over time, or differences in gene expression in different groups or treatments. In addition to mRNA transcripts, RNA-Seq can look at different populations of RNA to include total RNA, small RNA, such as miRNA, tRNA, and ribosomal profiling. RNA-Seq can also be used to determine exon/intron boundaries and verify or amend previously annotated 5' and 3' gene boundaries. Recent advances in RNA-Seq include single cell sequencing, in situ sequencing of fixed tissue, and native RNA molecule sequencing with single-molecule real-time ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Endosymbiont
An ''endosymbiont'' or ''endobiont'' is any organism that lives within the body or cells of another organism most often, though not always, in a mutualistic relationship. (The term endosymbiosis is from the Greek: ἔνδον ''endon'' "within", σύν ''syn'' "together" and βίωσις ''biosis'' "living".) Examples are nitrogen-fixing bacteria (called rhizobia), which live in the root nodules of legumes, single-cell algae inside reef-building corals and bacterial endosymbionts that provide essential nutrients to insects. There are two types of symbiont transmissions. In horizontal transmission, each new generation acquires free living symbionts from the environment. An example is the nitrogen-fixing bacteria in certain plant roots. Vertical transmission takes place when the symbiont is transferred directly from parent to offspring. It is also possible for both to be involved in a mixed-mode transmission, where symbionts are transferred vertically for some generation bef ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Group II Intron
Group II introns are a large class of self-catalytic ribozymes and mobile genetic elements found within the genes of all three domains of life. Ribozyme activity (e.g., self- splicing) can occur under high-salt conditions ''in vitro''. However, assistance from proteins is required for ''in vivo'' splicing. In contrast to group I introns, intron excision occurs in the absence of GTP and involves the formation of a lariat, with an A-residue branchpoint strongly resembling that found in lariats formed during splicing of nuclear pre-mRNA. It is hypothesized that pre-mRNA splicing (see spliceosome) may have evolved from group II introns, due to the similar catalytic mechanism as well as the structural similarity of the Group II Domain V substructure to the U6/U2 extended snRNA. Finally, their ability to site-specifically insert into DNA sites has been exploited as a tool for biotechnology. For example, group II introns can be modified to make site-specific genome insertions and del ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Intron
An intron is any nucleotide sequence within a gene that is not expressed or operative in the final RNA product. The word ''intron'' is derived from the term ''intragenic region'', i.e. a region inside a gene."The notion of the cistron .e., gene... must be replaced by that of a transcription unit containing regions which will be lost from the mature messenger – which I suggest we call introns (for intragenic regions) – alternating with regions which will be expressed – exons." (Gilbert 1978) The term ''intron'' refers to both the DNA sequence within a gene and the corresponding RNA sequence in RNA transcripts. The non-intron sequences that become joined by this RNA processing to form the mature RNA are called exons. Introns are found in the genes of most organisms and many viruses and they can be located in both protein-coding genes and genes that function as RNA (noncoding genes). There are four main types of introns: tRNA introns, group I introns, group II introns, and ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Neurospora Crassa
''Neurospora crassa'' is a type of red bread mold of the phylum Ascomycota. The genus name, meaning "nerve spore" in Greek, refers to the characteristic striations on the spores. The first published account of this fungus was from an infestation of French bakeries in 1843. ''Neurospora crassa'' is used as a model organism because it is easy to grow and has a haploid life cycle that makes genetics, genetic analysis simple since recessive traits will show up in the offspring. Analysis of genetic recombination is facilitated by the ordered arrangement of the products of meiosis in ''Neurospora'' ascospores. Its entire genome of seven chromosomes has been sequenced. ''Neurospora'' was used by Edward Tatum and George Wells Beadle in their experiments for which they won the Nobel Prize in Physiology or Medicine in 1958. Beadle and Tatum exposed ''N. crassa'' to x-rays, causing mutations. They then observed failures in metabolic pathways caused by errors in specific enzymes. This led t ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Wilbur Cross Medal
The Wilbur Cross Medal, or Wilbur Lucius Cross Medal for Alumni Achievement, is an award by the Yale University Graduate School Alumni Association to recognize "...distinguished achievements in scholarship, teaching, academic administration, and public service..." History Named in honor of Wilbur Lucius Cross, the medal is given to a small group of individuals (up to six) annually, and was first awarded in 1966 to Edgar S. Furniss. Recipients 2022 Virginia R. Domínguez Philip Ewell Sarah Tishkoff Kirk Johnson (scientist) 2021 Anat Admati Tamer Basar Donald Ingber Mary Miller 2020 Matthew State Brenda Elaine Stevenson Dorceta Taylor Veronica Vaida 2019 Ruth Garrett Millikan Douglas R. Green Susan M. Kidwell Urjit Patel 2018 Elizabeth W. Easton Kelsey Martin Marianne Mithun Tan Eng Chye 2017 Douglas Diamond Donna J. Haraway Eric J. Nestler Lawrence W. Sherman 2016 Arend Lijphart Ira Mellman Arthur Nozik Eleanor Sterling 2015 Carol S. Dweck Philip Hanawalt Jeremy ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Academy Of Medicine, Engineering And Science Of Texas
The Academy of Medicine, Engineering & Science of Texas (TAMEST) is a not-for-profit interdisciplinary scientific organization, whose membership consists of all Texas-based members of the three national academies, including ten Nobel laureates.The Academy of Medicine, Engineering & Science of Texas (2009). Retrieved 18 January 2008 Mission TAMEST's mission is "to provide broader recognition of the state's top achievers in medicine, engineering and science, and to build a stronger identity for Texas as an important destination and center of achievement in these fields." Membership TAMEST consists of all of the Texas-based members of the three national academies: the National Academy of Sciences, the National Academy of Engineering, and the National Institute of Medicine. The officers of the Board of Directors are Michael S. Brown, Kay Bailey Hutchison, David E. Daniel, J. Tinsley Oden, Francisco G. Cigarroa, William "Bill" R. Brinkley, and John Mendelsohn. The Nobel lau ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
National Academy Of Sciences
The National Academy of Sciences (NAS) is a United States nonprofit, non-governmental organization. NAS is part of the National Academies of Sciences, Engineering, and Medicine, along with the National Academy of Engineering (NAE) and the National Academy of Medicine (NAM). As a national academy, new members of the organization are elected annually by current members, based on their distinguished and continuing achievements in original research. Election to the National Academy is one of the highest honors in the scientific field. Members of the National Academy of Sciences serve '' pro bono'' as "advisers to the nation" on science, engineering, and medicine. The group holds a congressional charter under Title 36 of the United States Code. Founded in 1863 as a result of an Act of Congress that was approved by Abraham Lincoln, the NAS is charged with "providing independent, objective advice to the nation on matters related to science and technology. ... to provide scien ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
American Association For The Advancement Of Science
The American Association for the Advancement of Science (AAAS) is an American international non-profit organization with the stated goals of promoting cooperation among scientists, defending scientific freedom, encouraging scientific responsibility, and supporting scientific education and science outreach for the betterment of all humanity. It is the world's largest general scientific society, with over 120,000 members, and is the publisher of the well-known scientific journal ''Science''. History Creation The American Association for the Advancement of Science was created on September 20, 1848, at the Academy of Natural Sciences in Philadelphia, Pennsylvania. It was a reformation of the Association of American Geologists and Naturalists. The society chose William Charles Redfield as their first president because he had proposed the most comprehensive plans for the organization. According to the first constitution which was agreed to at the September 20 meeting, the goal of ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
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