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Ajmalan
Ajmalan is a parent hydride used in the IUPAC nomenclature of natural products and also in CAS nomenclature.. It is a 20-carbon alkaloid with six rings and seven chiral centres. The name is derived from ajmaline, an antiarrhythmic alkaloid isolated from the roots of ''Rauvolfia serpentina'' which is formally a dihydroxy-derivative of ajmalan. The –an ending indicates that ajmalan is partially saturated. Ajmaline itself is named after Hakim Ajmal Khan, a distinguished practitioner of the Unani school of traditional medicine in South Asia. The absolute configuration of the seven chiral carbon atoms in ajmalan is defined by convention, as is the numbering system. The stereochemistry is the same as that in naturally occurring ajmaline Ajmaline (also known by trade names Gilurytmal, Ritmos, and Aritmina) is an alkaloid that is classified as a 1-A antiarrhythmic agent. It is often used to induce arrhythmic contraction in patients suspected of having Brugada syndrome. Indiv ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Ajmaline
Ajmaline (also known by trade names Gilurytmal, Ritmos, and Aritmina) is an alkaloid that is classified as a 1-A antiarrhythmic agent. It is often used to induce arrhythmic contraction in patients suspected of having Brugada syndrome. Individuals suffering from Brugada syndrome will be more susceptible to the arrhythmogenic effects of the drug, and this can be observed on an electrocardiogram as an ST elevation. The compound was first isolated by Salimuzzaman Siddiqui in 1931 from the roots of '' Rauvolfia serpentina''. He named it ''ajmaline'', after Hakim Ajmal Khan, one of the most illustrious practitioners of Unani medicine in South Asia. Ajmaline can be found in most species of the genus '' Rauvolfia'' as well as ''Catharanthus roseus''. In addition to Southeast Asia, ''Rauvolfia'' species have also been found in tropical regions of India, Africa, South America, and some oceanic islands. Other indole alkaloids found in ''Rauvolfia'' include reserpine, ajmalicine, serpen ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Hakim Ajmal Khan
Mohammad Ajmal Khan (11 February 1868 – 29 December 1927), better known as Hakim Ajmal Khan, was a physician in Delhi, India, and one of the founders of the Jamia Millia Islamia University. He also founded another institution, Ayurvedic and Unani Tibbia College, better known as Tibbia College, situated in Karol Bagh, Delhi. He was the only muslim to chair a session of the Hindu Mahasabha. He became the university's first chancellor in 1920 and remained in office until his death in 1927.Profile of Hakim Ajmal Khan Jamia Millia Islamia website, Retrieved 22 August 2019 Biography Born on 11 February 1868 (17 Shawwal 1284), Khan descended from a line of physicians who had come ...[...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
South Asia
South Asia is the southern subregion of Asia, which is defined in both geographical and ethno-cultural terms. The region consists of the countries of Afghanistan, Bangladesh, Bhutan, India, Maldives, Nepal, Pakistan, and Sri Lanka.;;;;;;;; Topographically, it is dominated by the Indian subcontinent and defined largely by the Indian Ocean on the south, and the Himalayas, Karakoram, and Pamir mountains on the north. The Amu Darya, which rises north of the Hindu Kush, forms part of the northwestern border. On land (clockwise), South Asia is bounded by Western Asia, Central Asia, East Asia, and Southeast Asia. The South Asian Association for Regional Cooperation (SAARC) is an economic cooperation organization in the region which was established in 1985 and includes all eight nations comprising South Asia. South Asia covers about , which is 11.71% of the Asian continent or 3.5% of the world's land surface area. The population of South Asia is about 1.9 billion or about one- ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Alkaloids Found In Apocynaceae
Alkaloids are a class of basic, naturally occurring organic compounds that contain at least one nitrogen atom. This group also includes some related compounds with neutral and even weakly acidic properties. Some synthetic compounds of similar structure may also be termed alkaloids. In addition to carbon, hydrogen and nitrogen, alkaloids may also contain oxygen, sulfur and, more rarely, other elements such as chlorine, bromine, and phosphorus.Chemical Encyclopedia: alkaloids xumuk.ru Alkaloids are produced by a large variety of organisms including , , |
Yohimban
Yohimban is a chemical compound. It is the base chemical structure of various alkaloids in the ''Rauvolfia'' and ''Corynanthe'' plant genera, including yohimbine, rauwolscine, corynanthine, ajmalicine, reserpine, deserpidine, and rescinnamine Rescinnamine, known by the brand names moderil, cinnasil, and anaprel, is an angiotensin-converting enzyme inhibitor used as an antihypertensive drug. It is a vinca alkaloid obtained from ''Rauvolfia serpentina'' and other species of ''Rauvolf ..., among others. References {{alkaloid-stub Tryptamine alkaloids Quinolizidine alkaloids Heterocyclic compounds with 5 rings ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Dawn (newspaper)
''Dawn'' is a Pakistani English-language newspaper that was launched in British India in 1941. It is the largest English newspaper in Pakistan, and also serves as the country's newspaper of record. ''Dawn'' is the flagship publication of the Dawn Media Group, which also owns local radio station ''CityFM89'' as well as the marketing and media magazine ''Aurora''. Muhammad Ali Jinnah, Pakistan's founding father, launched the newspaper in Delhi on 26 October 1941, with the goal of establishing it as a mouthpiece for the All-India Muslim League. The first issue was printed at Latifi Press on 12 October 1942. Based in Karachi, it also maintains offices in Lahore and the capital city of Islamabad, in addition to having correspondents abroad. , it has a weekday circulation of over 109,000. The newspaper's current chief editor is Zaffar Abbas. History ''Dawn'' began as a weekly publication, based in New Delhi. Under the instruction of Jinnah, it became the official organ of the All ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Parent Hydride
In chemistry, a parent hydride in IUPAC nomenclature refers to a main group compound with the formula , where A is a main group element. The names of parent hydrides end with ''-ane'', analogous with the nomenclature for alkanes. Derivatives of parent hydrides are named by appending prefixes or suffixes to the name of the parent hydride to indicate the substituents that replace the hydrogen atoms. Parent hydrides are used in both the organic nomenclature, and inorganic nomenclature systems. (Red Book) Par. IR-6 ''Parent Hydride Names and Substitutive Nomenclature'' - Full text PDF Reactions and structure Parent hydrides are useful reference compounds, but ...[...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Unani
Unani or Yunani medicine (Urdu: ''tibb yūnānī'') is Perso-Arabic traditional medicine as practiced in Muslim culture in South Asia and modern day Central Asia. Unani medicine is pseudoscientific. The Indian Medical Association describes Unani practitioners who claim to practice medicine as quacks. The term '' Yūnānī'' means "Greek", as the Perso-Arabic system of medicine was based on the teachings of the Greek physicians Hippocrates and Galen. The Hellenistic origin of Unani medicine is still visible in its being based on the classical four humours: phlegm (), blood (''dam''), yellow bile (''ṣafrā'') and black bile (''saudā), but it has also been influenced by Indian and Chinese traditional systems. History Arab and Persian elaborations upon the Greek system of medicine by figures like Ibn Sina and al-Razi influenced the early development of Unani. Unani medicine interacted with Indian Buddhist medicine at the time of Alaxander's invasion of India. There was a ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
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