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Acute HME Syndrome
Acute hepatomyoencephalopathy (HME) syndrome is the name given to a multi-system disease affecting the liver, muscle and brain which is now known to be caused by phytotoxins. After extensive investigation the culprit has been found to be the beans of a common herb in India, ''Cassia occidentalis''. In many districts of western Uttar Pradesh, Uttarakhand, Odisha and Haryana, India, outbreaks of an acute "encephalopathy" syndrome, dubbed as a "mysterious disease", have been an annual feature for many years. At least 500-700 young previously healthy children had been losing their lives every year in this region. The disease affected rural young children during the winter months of September to December, with fatality rates around 75-80%. It was first assumed it to be a kind of viral encephalitis. Many national investigating agencies failed to diagnose the entity for many years. Mechanism The acute severe '' C. occidentalis'' poisoning in children affects multiple systems. Functional an ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Phytotoxin
Phytotoxins are substances that are poisonous or toxic to the growth of plants. Phytotoxic substances may result from human activity, as with herbicides, or they may be produced by plants, by microorganisms, or by naturally occurring chemical reactions. The term is also used to describe toxic chemicals produced by plants themselves, which function as defensive agents against their predators. Most examples pertaining to this definition of phytotoxin are members of various classes of specialised or secondary metabolites, including alkaloids, terpenes, and especially phenolics, though not all such compounds are toxic or serve defensive purposes. Phytotoxins may also be toxic to humans. Toxins produced by plants Alkaloids Alkaloids are derived from amino acids, and contain nitrogen. They are medically important by interfering with components of the nervous system affecting membrane transport, protein synthesis, and enzyme activities. They generally have a bitter taste. Alkaloids ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Bijnor District
Bijnor district is one of the 75 districts in the state of Uttar Pradesh in India. Bijnor city is the district headquarters. The government of Uttar Pradesh seeks it to be included in National Capital Region (NCR) due to its close proximity to NCT of Delhi. Bijnor is notable for its sugarcane production and mills, with two of the top five sugar mills situated in the district. History Bijnor district was created in 1817 out of part of Moradabad district, and it was originally called Nagina district after its headquarters at Nagina. The headquarters was relocated to Bijnor in 1824, although the district was still called "Nagina district" until 1837, when it officially became known as Bijnor district. Medieval history In 1399, the district was ravaged by Timur. Later, during the time of Akbar, Bijnor was part of his Mughal Empire. In the early 18th century, the Rohilla Pashtuns established their independence in the area called by the Rohilkhand. Around 1748, the Rohilla chief A ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
523-533
5 (five) is a number, numeral and digit. It is the natural number, and cardinal number, following 4 and preceding 6, and is a prime number. It has attained significance throughout history in part because typical humans have five digits on each hand. In mathematics 5 is the third smallest prime number, and the second super-prime. It is the first safe prime, the first good prime, the first balanced prime, and the first of three known Wilson primes. Five is the second Fermat prime and the third Mersenne prime exponent, as well as the third Catalan number, and the third Sophie Germain prime. Notably, 5 is equal to the sum of the ''only'' consecutive primes, 2 + 3, and is the only number that is part of more than one pair of twin primes, ( 3, 5) and (5, 7). It is also a sexy prime with the fifth prime number and first prime repunit, 11. Five is the third factorial prime, an alternating factorial, and an Eisenstein prime with no imaginary part and real part of the form 3p ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
