Access To COVID-19 Tools Accelerator
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Access To COVID-19 Tools Accelerator
The Access to COVID-19 Tools Accelerator (ACT Accelerator or ACT-A), or the ''Global Collaboration to Accelerate the Development, Production and Equitable Access to New COVID-19 diagnostics, therapeutics and vaccines'', is a G20 initiative announced by pro-tem Chair Mohammed al-Jadaan on 24 April 2020. A call to action was published simultaneously by the World Health Organization (WHO) on 24 April. As of January 2022, it was the largest international effort to achieve equitable access to COVID-19 health technologies. Definition The ACT Accelerator is a multinational collaboration, and multistakeholder initiative including the World Health Organization, the Coalition for Epidemic Preparedness Innovations (CEPI), FIND, GAVI the Vaccine Alliance, the Global Fund, UNICEF, Unitaid, Wellcome, the World Bank and governments, to raise financial support of accelerated research and development, production, and globally-equitable access to COVID-19 tests, therapies, and vaccines. It is a f ...
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Mohammed Al-Jadaan
Mohammed Al-Jadaan ( ar, محمد بن عبد الله الجدعان; born 1963) is a commercial lawyer and co-founder of Al-Jadaan and Partners Law Firm who has served as Saudi Arabia's minister of finance since November 2016 and concurrently as acting minister of economy and planning since March 2020. He replaced Ibrahim Al-Assaf in the post. On 6 March 2020 King Salman issued a royal order, appointing Mohammed Al Jadaan as acting minister of economy and planning in addition to his work as minister of finance replacing Mohammed Al Tuwaijri in the post. Prior to his appointment as Minister of Finance Mohammed Al-Jadaan was the chairman of Capital Markets Authority where he oversaw the opening of the Tadawul Stock Exchange and the loosening of Saudi's regulatory framework to foreign investors. He also previously served as a special adviser to the board of Morgan Stanley Saudi Arabia. References External links Minister CV {{DEFAULTSORT:Jadaan, Mohammed al Mohammed ...
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AstraZeneca
AstraZeneca plc () is a British-Swedish multinational pharmaceutical and biotechnology company with its headquarters at the Cambridge Biomedical Campus in Cambridge, England. It has a portfolio of products for major diseases in areas including oncology, cardiovascular, gastrointestinal, infection, neuroscience, respiratory, and inflammation. It has been involved in developing the Oxford–AstraZeneca COVID-19 vaccine. The company was founded in 1999 through the merger of the Swedish Astra AB and the British Zeneca Group (itself formed by the demerger of the pharmaceutical operations of Imperial Chemical Industries in 1993). Since the merger it has been among the world's largest pharmaceutical companies and has made numerous corporate acquisitions, including Cambridge Antibody Technology (in 2006), MedImmune (in 2007), Spirogen (in 2013) and Definiens (by MedImmune in 2014). It has its research and development concentrated in three strategic centres: Cambridge, England; ...
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COVAX
COVID-19 Vaccines Global Access, abbreviated as COVAX, is a worldwide initiative aimed at equitable access to COVID-19 vaccines directed by the GAVI vaccine alliance, the Coalition for Epidemic Preparedness Innovations (CEPI), and the World Health Organization (WHO), alongside key delivery partner UNICEF. It is one of the four pillars of the Access to COVID-19 Tools Accelerator, an initiative begun in April 2020 by the WHO, the European Commission, and the government of France as a response to the COVID-19 pandemic. COVAX coordinates international resources to enable low-to-middle-income countries equitable access to COVID-19 tests, therapies, and vaccines. UNICEF is the key delivery partner, leveraging its experience as the largest single vaccine buyer in the world and working on the procurement of COVID-19 vaccine doses, as well as logistics, country readiness and in-country delivery. By 19 October 2020, 184 countries had joined COVAX. COVAX began distributing vaccines in Fe ...
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Presidency Of Donald Trump
Donald Trump's tenure as the 45th president of the United States began with his inauguration on January 20, 2017, and ended on January 20, 2021. Trump, a Republican from New York City, took office following his Electoral College victory over Democratic nominee Hillary Clinton in the 2016 presidential election, in which he lost the popular vote to Clinton by nearly 3 million votes. Upon his inauguration, he became the first president in American history without prior public office or military background. Trump made an unprecedented number of false or misleading statements during his campaign and presidency. His presidency ended with defeat in the 2020 presidential election to Democrat Joe Biden after one term in office. Trump was unsuccessful in his efforts to repeal the Affordable Care Act but took measures to hinder its functioning and rescinded the individual mandate. Trump sought substantial spending cuts to major welfare programs, including Medicare and Medicai ...
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COVID-19 Vaccine
A COVID19 vaccine is a vaccine intended to provide acquired immunity against severe acute respiratory syndrome coronavirus 2 (SARS‑CoV‑2), the virus that causes coronavirus disease 2019 ( COVID19). Prior to the COVID19 pandemic, an established body of knowledge existed about the structure and function of coronaviruses causing diseases like severe acute respiratory syndrome (SARS) and Middle East respiratory syndrome (MERS). This knowledge accelerated the development of various vaccine platforms during early 2020. The initial focus of SARS-CoV-2 vaccines was on preventing symptomatic, often severe illness. In January 2020, the SARS-CoV-2 genetic sequence data was shared through GISAID, and by March 2020, the global pharmaceutical industry announced a major commitment to address COVID19. In 2020, the first COVID19 vaccines were developed and made available to the public through emergency authorizations and conditional approvals. Initially, most COVID19 vaccines were two ...
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Global Research Collaboration For Infectious Disease Preparedness
The Global Research Collaboration for Infectious Disease Preparedness (GloPID-R) is an international initiative to anticipate and prepare for future threats from infectious diseases. GloPID-R is intended to be a means for facilitating communication and collaboration between its member bodies, as opposed to a funding or disaster response entity. Its secretariat is funded by the European Union through its Horizon 2020 initiative. History GloPID-R was launched in February 2013 in Brussels, Belgium on the recommendation of the Heads of International Research Organizations (HIROs). On February 11-12, 2020, GloPID-R co-hosted an event with the World Health Organization's R&D Blueprint called “2019 novel Coronavirus Global research and innovation forum: towards a research roadmap”. Participants in this conference identified a number of key research priorities which served as the basis on which funding decisions were made in response to the COVID-19 pandemic. __TOC__ Membership Gl ...
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Hong Kong University
The University of Hong Kong (HKU) (Chinese: 香港大學) is a public research university in Hong Kong. Founded in 1887 as the Hong Kong College of Medicine for Chinese, it is the oldest tertiary institution in Hong Kong. HKU was also the first university established by the British in East Asia. As of December 2022, HKU ranks 21st internationally and third in Asia by '' QS'', and 31st internationally and fourth in Asia by ''Times Higher Education''. It has been ranked as the most international university in the world as well as one of the most prestigious universities in Asia. Today, HKU has ten academic faculties with English as the main language of instruction. The University of Hong Kong was also the first team in the world to successfully isolate the coronavirus SARS-CoV, the causative agent of SARS. History Founding The origins of The University of Hong Kong can be traced back to the Hong Kong College of Medicine for Chinese founded in 1887 by Ho Kai later known as S ...
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Novavax
Novavax, Inc. is an American biotechnology company based in Gaithersburg, Maryland that develops vaccines to counter serious infectious diseases. Prior to 2020, company scientists developed experimental vaccines for influenza and respiratory syncytial virus (RSV), as well as Ebola and other emerging infectious diseases. During 2020, the company redirected its efforts to focus on development and approval of its NVX-CoV2373 vaccine for COVID-19. Their vaccine, Nuvaxovid, was approved in the European Union at the end of 2021 and in Canada in February 2022, as the fifth vaccine against COVID-19, following Pfizer/BioNTech, Moderna, Janssen and AstraZeneca. History In June 2013, Novavax acquired the Matrix-M adjuvant platform with the purchase of Swedish company Isconova AB and renamed its new subsidiary Novavax AB. ResVax In March 2015, the company completed a Phase I trial for its Ebola vaccine candidate, as well as a phase II study in adults for its RSV vaccine, which wo ...
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MRNA-1273
The Moderna COVID19 vaccine (INN: elasomeran), sold under the brand name Spikevax, is a COVID-19 vaccine developed by American company Moderna, the United States National Institute of Allergy and Infectious Diseases (NIAID), and the Biomedical Advanced Research and Development Authority (BARDA). Depending on the jurisdiction, it is authorized for use in people aged six months, twelve years, or eighteen years and older. It provides protection against COVID-19 which is caused by infection by the SARS-CoV-2 virus. It is designed to be administered as two or three 0.5 mL doses given by intramuscular injection at an interval of at least 28 days apart. It is an mRNA vaccine composed of nucleoside-modified mRNA (modRNA) encoding a spike protein of SARS-CoV-2, which is encapsulated in lipid nanoparticles. It is authorized for use at some level in many countries. In August and September 2022, bivalent versions of the vaccine (Moderna COVID-19 Vaccine, Bivalent) containing elasome ...
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Moderna
Moderna, Inc. ( ) is an American pharmaceutical and biotechnology company based in Cambridge, Massachusetts that focuses on RNA therapeutics, primarily mRNA vaccines. These vaccines use a copy of a molecule called messenger RNA (mRNA) to produce an immune response. The company's only commercial product is the Moderna COVID-19 vaccine, marketed as Spikevax. As of 2022, the company has 44 treatment and vaccine candidates, of which 21 have entered clinical trials. Targets for vaccine candidates include influenza, HIV, respiratory syncytial virus, Epstein–Barr virus, the Nipah virus, chikungunya, a combined single-shot COVID-19 booster and influenza vaccine, a cytomegalovirus vaccine, and two cancer vaccines. The company's pipeline also includes candidates for cancer immunotherapy using OX40 ligand, interleukin 23, IL36G, and interleukin 12 as well as, in partnership with AstraZeneca, a regenerative medicine treatment that encodes vascular endothelial growth factor A to stimul ...
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Institut Pasteur
The Pasteur Institute (french: Institut Pasteur) is a French non-profit private foundation dedicated to the study of biology, micro-organisms, diseases, and vaccines. It is named after Louis Pasteur, who invented pasteurization and vaccines for anthrax and rabies. The institute was founded on 4 June 1887, and inaugurated on 14 November 1888. For over a century, the Institut Pasteur has researched infectious diseases. This worldwide biomedical research organization based in Paris was the first to isolate HIV, the virus that causes AIDS, in 1983. Over the years, it has been responsible for discoveries that have enabled medical science to control diseases such as diphtheria, tetanus, tuberculosis, poliomyelitis, influenza, yellow fever, and plague. Since 1908, ten Institut Pasteur scientists have been awarded the Nobel Prize for medicine and physiology—the 2008 Nobel Prize in Physiology or Medicine was shared between two Pasteur scientists. History The Institut Pasteur was ...
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Inovio
Inovio Pharmaceuticals is an American biotechnology company focused on the discovery, development, and commercialization of Synthetic genomics, synthetic DNA products for treating cancers and infectious diseases. In April 2020, Inovio was among some 100 companies, academic centers, or research organizations developing a vaccine candidate for treating people infected with Coronavirus disease 2019, COVID-19, with more than 170 total vaccine candidates in development (June 2020). Technology The Inovio technology is based on inserting Biological engineering, engineered DNA into cells, where it becomes transcribed into mRNA and translated into proteins. The proteins encoded by the DNA elicit immune response to antigens from cancers and viruses, by stimulating the production of T cells and antibody, antibodies that aid recovery. The technology can be "targeted" to specific types of cancer and immune diseases, such as those produced by a virus. During a meeting of the White House Coron ...
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