ALS Therapy Development Foundation
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ALS Therapy Development Foundation
The ALS Therapy Development Institute (ALS TDI) is a non-profit biotechnology research organization focused on finding treatments for amyotrophic lateral sclerosis (ALS). With a staff including more than 30 scientists, it operates a research and development program centered on ALS. History ALS TDI was founded as the ALS Therapy Development Foundation (ALS TDF) in 1999 by James Heywood, Robert Bonazoli, and Melinda Marsh Heywood after James' brother, Stephen Heywood, was diagnosed with the disease. Dr. Tennore Ramesh joined ALS-TDF when his sister in law was diagnosed with ALS and setup the research facility and served as Chief Scientific Officer from inception until 2003. The organization was initially funded through a donation from Stephen, as well as one from Alex and Brit d'Arbeloff. The Foundation's first therapy concept was to replace EAAT2 protein using gene therapy. In 2004, the Foundation moved to a location in Cambridge, Massachusetts with an in-house lab. ALS TDF cons ...
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Non-profit
A nonprofit organization (NPO) or non-profit organisation, also known as a non-business entity, not-for-profit organization, or nonprofit institution, is a legal entity organized and operated for a collective, public or social benefit, in contrast with an entity that operates as a business aiming to generate a profit for its owners. A nonprofit is subject to the non-distribution constraint: any revenues that exceed expenses must be committed to the organization's purpose, not taken by private parties. An array of organizations are nonprofit, including some political organizations, schools, business associations, churches, social clubs, and consumer cooperatives. Nonprofit entities may seek approval from governments to be tax-exempt, and some may also qualify to receive tax-deductible contributions, but an entity may incorporate as a nonprofit entity without securing tax-exempt status. Key aspects of nonprofits are accountability, trustworthiness, honesty, and openness to eve ...
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Muscular Dystrophy Association
The Muscular Dystrophy Association (MDA) is an American 501(c)(3) umbrella organization that works to support people with neuromuscular diseases. Founded in 1950 by Paul Cohen, who lived with muscular dystrophy, it works to combat neuromuscular disorders by funding research, providing medical and community services and educating health professionals and the general public and contributed more than $1 billion toward researching therapies and cures, helping to fund the identification of the dystrophin gene responsible for Duchenne muscular dystrophy as well as prospective treatments. Renowned for '' The Jerry Lewis Telethon'', the annual Labor Day telecast aired live from 1966 to 2010, hosted by Jerry Lewis, who also served as MDA's national chairman from the late 50s to the early 2010s. Frank Sinatra, Don Rickles, Sammy Davis, Jr., Milton Berle, Wayne Newton, Norm Crosby, Don Francisco, Tony Orlando, Johnny Carson, Aretha Franklin, Maureen McGovern, Diana Ross, Angela Lansbury and ...
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Wolf Blitzer
Wolf Isaac Blitzer (born March 22, 1948) is an American journalist, television news anchor, and author who has been a CNN reporter since 1990, and who currently serves as one of the principal anchors at the network. He is the host of ''The Situation Room with Wolf Blitzer'' and until 2021, served as the network's lead political anchor. Early life Blitzer was born in Augsburg, Bavaria, Germany near Munich in 1948, during post-World War II Allied occupation the son of Cesia Blitzer (née Zylberfuden), a homemaker, and David Blitzer, a home builder. His parents were Polish Jewish refugees from German-occupied Poland who survived the Auschwitz concentration camp; his grandparents, two uncles, and two aunts on his father's side were all murdered there. Blitzer and his family immigrated to the United States under the provisions of the 1948 Displaced Persons Act. He was raised in Buffalo, New York, and graduated from Kenmore West Senior High School. He received a Bachelor of Arts in hi ...
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Nancy O'Dell
Nancy O'Dell (born Nancy Evelyn Humphries; 1966) is an American television host and entertainment journalist. She served as co-anchor of the syndicated entertainment news show ''Entertainment Tonight'' from January 3, 2011, to August 2, 2019. Early life O'Dell was born in 1966 in Sumter, South Carolina, and moved to Myrtle Beach as an infant. She has one sister. After her 1984 graduation from the now-defunct Coastal Academy High School, she graduated with a ''summa cum laude'' bachelor's degree in marketing from Clemson University in 1990. At Clemson, O'Dell joined Kappa Kappa Gamma. She won the Miss South Carolina pageant in 1987 and represented the state at Miss America 1988, where she won a preliminary swimsuit award. In 1990, in the Miss South Carolina USA pageant, she finished first runner-up to Gina Tolleson, who became the first runner-up in Miss USA 1990 before winning Miss World that year. Career Early career O'Dell began her broadcasting career as a reporter and anchor ...
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Shaquille O'Neal
Shaquille Rashaun O'Neal ( ; born March 6, 1972), known commonly as "Shaq" ( ), is an American former professional basketball player who is a sports analyst on the television program ''Inside the NBA''. O'Neal is regarded as one of the greatest basketball players and centers of all time. He is a and center who played for six teams over his 19-year career in the National Basketball Association (NBA) and is a four-time NBA champion. After playing college basketball for the LSU Tigers, O'Neal was drafted by the Orlando Magic with the first overall pick in the 1992 NBA draft. He quickly became one of the best centers in the league, winning Rookie of the Year in 1992–93 and leading his team to the 1995 NBA Finals. After four years with the Magic, O'Neal signed as a free agent with the Los Angeles Lakers. They won three consecutive championships in 2000, 2001, and 2002. Amid tension between O'Neal and Kobe Bryant, O'Neal was traded to the Miami Heat in 2004, and his ...
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Jimmy Kimmel
James Christian Kimmel (born November 13, 1967) is an American television host, comedian, writer, and producer. He is the host and executive producer of ''Jimmy Kimmel Live!'', a late-night talk show that premiered on ABC on January 26, 2003, at Hollywood Masonic Temple in Hollywood, California; and on April 1, 2019, at a secondary home, the Zappos Theater on the Las Vegas Strip. Kimmel hosted the Primetime Emmy Awards in 2012, 2016 and 2020, and the Academy Awards in 2017 and 2018. Before hosting ''Jimmy Kimmel Live!'', Kimmel was the co-host of Comedy Central's '' The Man Show'' and ''Win Ben Stein's Money''. Kimmel has also produced such shows as ''Crank Yankers'', ''Sports Show with Norm Macdonald'', and ''The Andy Milonakis Show''. In 2018, ''Time'' named him as one of " The World's 100 Most Influential People". Kimmel is the longest-working of all current late-night talk show hosts in the United States, following Conan O’Brien’s retirement from hosting a late-nigh ...
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Kelly Clarkson
Kelly Brianne Clarkson (born April 24, 1982) is an American singer, songwriter, author, and television personality. She rose to fame after winning the first season of ''American Idol'' in 2002, which earned her a record deal with RCA. Her debut single, " A Moment Like This", topped the US ''Billboard'' Hot 100, and became the country's best selling single of 2002. It was included on her debut studio album, '' Thankful'' (2003), which debuted atop the ''Billboard'' 200. Trying to reinvent her image, Clarkson parted ways with ''Idol'' management and shifted to pop rock for her second studio album, '' Breakaway'' (2004). Supported by four US top-ten singles – the title track, "Since U Been Gone", " Behind These Hazel Eyes", and " Because of You" – ''Breakaway'' sold over 12 million copies worldwide and won two Grammy Awards. Clarkson took further creative control for her third studio album, ''My December'' (2007), co-writing all of its tracks and becoming its executive prod ...
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Chili Pepper
Chili peppers (also chile, chile pepper, chilli pepper, or chilli), from Nahuatl '' chīlli'' (), are varieties of the berry-fruit of plants from the genus ''Capsicum'', which are members of the nightshade family Solanaceae, cultivated for their pungency. Chili peppers are widely used in many cuisines as a spice to add "heat" to dishes. Capsaicin and related compounds known as capsaicinoids are the substances giving chili peppers their intensity when ingested or applied topically. While ''chili peppers'' are (to varying degrees) pungent or "spicy", there are other varieties of capsicum such as bell peppers (UK: peppers) which generally provide additional sweetness and flavor to a meal rather than “heat.” Chili peppers are believed to have originated somewhere in Central or South America. and were first cultivated in Mexico. After the Columbian Exchange, many cultivars of chili pepper spread around the world, used for both food and traditional medicine. This led to a ...
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University Of Massachusetts Medical School
The University of Massachusetts Chan Medical School is a public medical school in Worcester, Massachusetts. It is part of the University of Massachusetts system. It is home to three schools: the T.H. Chan School of Medicine, the Morningside Graduate School of Biomedical Sciences, and the Tan Chingfen Graduate School of Nursing, as well as a biomedical research enterprise and a range of public-service initiatives throughout the state. History UMMS was established by the 162nd Massachusetts General Court in 1962 to provide residents of the commonwealth an opportunity to study medicine at an affordable cost and to increase the number of primary-care physicians practicing in the commonwealth's under-served areas. The School of Medicine accepted its first class of 16 students in 1970. Six years later a 371-bed hospital opened on campus; the Graduate School of Biomedical Sciences opened in 1979, and the Graduate School of Nursing opened in 1986. In 1998 the UMMS system of hospitals a ...
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Harvard Medical School
Harvard Medical School (HMS) is the graduate medical school of Harvard University and is located in the Longwood Medical Area of Boston, Massachusetts. Founded in 1782, HMS is one of the oldest medical schools in the United States and is consistently ranked first for research among medical schools by '' U.S. News & World Report''. Unlike most other leading medical schools, HMS does not operate in conjunction with a single hospital but is directly affiliated with several teaching hospitals in the Boston area. Affiliated teaching hospitals and research institutes include Dana–Farber Cancer Institute, Massachusetts General Hospital, Brigham and Women's Hospital, Beth Israel Deaconess Medical Center, Boston Children's Hospital, McLean Hospital, Cambridge Health Alliance, The Baker Center for Children and Families, and Spaulding Rehabilitation Hospital. History Harvard Medical School was founded on September 19, 1782, after President Joseph Willard presented a report with ...
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Massachusetts General Hospital
Massachusetts General Hospital (Mass General or MGH) is the original and largest teaching hospital of Harvard Medical School located in the West End neighborhood of Boston, Massachusetts. It is the third oldest general hospital in the United States and has a capacity of 999 beds. With Brigham and Women's Hospital, it is one of the two founding members of Mass General Brigham (formerly known as Partners HealthCare), the largest healthcare provider in Massachusetts. Massachusetts General Hospital houses the largest hospital-based research program in the world, the Mass General Research Institute, with an annual research budget of more than $1 billion in 2019. It is currently ranked as the #8 best hospital in the United States by '' U.S. News & World Report''. In , ''The Boston Globe'' ranked MGH the fifth best place to work out of Massachusetts companies with over 1,000 employees. History Founded in 1811, the original hospital was designed by the famous American architect Char ...
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Ice Bucket Challenge
The Ice Bucket Challenge, sometimes called the ALS Ice Bucket Challenge, is an activity involving the pouring of a bucket of ice water over a person's head, either by another person or self-administered, to promote awareness of the disease amyotrophic lateral sclerosis (ALS, also known as motor neuron disease or Lou Gehrig's disease) and encourage donations to research. The challenge was co-founded by Pat Quinn and Pete Frates; it went viral on social media during July–August 2014. In the United States, many people participated for the ALS Association, and in the United Kingdom, many people participated for the Motor Neurone Disease Association, although some individuals opted to donate their money from the Ice Bucket Challenge to other organizations. The challenge encourages nominated participants to be filmed having a bucket of ice water poured on their heads and then nominating others to do the same. A common stipulation is that nominated participants have 24 hours to comp ...
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