AIDS Origins Opposed To Scientific Consensus
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AIDS Origins Opposed To Scientific Consensus
Various fringe theories have arisen to speculate about purported alternative origins for the human immunodeficiency virus (HIV) and the acquired immunodeficiency syndrome (AIDS), with claims ranging from it being due to accidental exposure to supposedly purposeful acts. Several inquiries and investigations have been carried out as a result, and each of these theories has consequently been determined to be based on unfounded and/or false information. HIV has been shown to have evolved from or be closely related to the simian immunodeficiency virus (SIV) in West Central Africa sometime in the early 20th century. HIV was discovered in the 1980s by the French scientist Luc Montagnier. Before the 1980s, HIV was an unknown deadly disease. Discredited theories Smallpox vaccination theory In 1987 there was some consideration given to the possibility that the "AIDS epidemic may have been triggered by the mass vaccination campaign which eradicated smallpox". An article in ''The Times'' s ...
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Human Immunodeficiency Virus
The human immunodeficiency viruses (HIV) are two species of ''Lentivirus'' (a subgroup of retrovirus) that infect humans. Over time, they cause AIDS, acquired immunodeficiency syndrome (AIDS), a condition in which progressive failure of the immune system allows life-threatening opportunistic infections and cancers to thrive. Without treatment, average survival time after infection with HIV is estimated to be 9 to 11 years, depending on the HIV subtype. In most cases, HIV is a sexually transmitted infection and HIV/AIDS#Transmission, occurs by contact with or transfer of blood, pre-ejaculate, semen, and Vaginal lubrication, vaginal fluids. Non-sexual transmission can occur from an infected mother to her infant during pregnancy, during childbirth by exposure to her blood or vaginal fluid, and through breast milk. Within these bodily fluids, HIV is present as both free virus particles and virus within infected White blood cell, immune cells. Research has shown (for both same-sex ...
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Edward Hooper (journalist)
The oral polio vaccine (OPV) AIDS hypothesis is a now-discredited hypothesis that the AIDS pandemic originated from live polio vaccines prepared in chimpanzee tissue cultures, accidentally contaminated with simian immunodeficiency virus and then administered to up to one million Africans between 1957 and 1960 in experimental mass vaccination campaigns. Data analyses in molecular biology and phylogenetic studies contradict the OPV AIDS hypothesis; consequently, scientific consensus regards the hypothesis as disproven. A 2004 ''Nature'' article has described the hypothesis as "refuted". Background: polio vaccines Two vaccines are used throughout the world to combat poliomyelitis. The first, a polio vaccine developed by Jonas Salk, is an ''inactivated poliovirus vaccine'' (IPV), consisting of a mixture of three wild, virulent strains of poliovirus, grown in a type of monkey kidney tissue culture (Vero cell line), and made noninfectious by formaldehyde treatment. The second vacci ...
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Visna-maedi Virus
''Visna-maedi virus'' (also known as ''Visna virus'', ''Maedi-visna virus'' and ''Ovine lentivirus'') from the genus '' Lentivirus'' and subfamily ''Orthoretrovirinae'', is a retrovirus that causes encephalitis and chronic pneumonitis in sheep. It is known as visna when found in the brain, and maedi when infecting the lungs. Lifelong, persistent infections in sheep occur in the lungs, lymph nodes, spleen, joints, central nervous system, and mammary glands; The condition is sometimes known as ovine progressive pneumonia (OPP), particularly in the United States, or Montana sheep disease. White blood cells of the monocyte/macrophage lineage are the main target of the virus. Viral infection First described in 1954 by Bjorn Sigurdsson in Iceland, Maedi-visna virus was the first lentivirus to be isolated and characterized, accomplished in 1957 by Sigurdsson. ''Maedi'' ( Icelandic ' 'dyspnoea') and ''visna'' (Icelandic ' 'wasting' or 'shrinking' of the spinal cord) refer to endemic she ...
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Fort Detrick
Fort Detrick () is a United States Army Futures Command installation located in Frederick, Maryland. Historically, Fort Detrick was the center of the U.S. biological weapons program from 1943 to 1969. Since the discontinuation of that program, it has hosted most elements of the United States biological defense program. As of the early 2010s, Fort Detrick's campus supports a multi-governmental community that conducts biomedical research and development, medical materiel management, global medical communications and the study of foreign plant pathogens. The lab is known to research pathogens such as Ebola and smallpox. It is home to the U.S. Army Medical Research and Development Command (USAMRDC), with its bio-defense agency, the U.S. Army Medical Research Institute of Infectious Diseases (USAMRIID). It also hosts the National Cancer Institute-Frederick (NCI-Frederick) and is home to the National Interagency Confederation for Biological Research (NICBR) and National Interagen ...
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East Germany
East Germany, officially the German Democratic Republic (GDR; german: Deutsche Demokratische Republik, , DDR, ), was a country that existed from its creation on 7 October 1949 until its dissolution on 3 October 1990. In these years the state was a part of the Eastern Bloc in the Cold War. Commonly described as a communist state, it described itself as a socialist "workers' and peasants' state".Patrick Major, Jonathan Osmond, ''The Workers' and Peasants' State: Communism and Society in East Germany Under Ulbricht 1945–71'', Manchester University Press, 2002, Its territory was administered and occupied by Soviet forces following the end of World War II—the Soviet occupation zone of the Potsdam Agreement, bounded on the east by the Oder–Neisse line. The Soviet zone surrounded West Berlin but did not include it and West Berlin remained outside the jurisdiction of the GDR. Most scholars and academics describe the GDR as a totalitarian dictatorship. The GDR was establish ...
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Humboldt University
Humboldt-Universität zu Berlin (german: Humboldt-Universität zu Berlin, abbreviated HU Berlin) is a German public research university in the central borough of Mitte in Berlin. It was established by Frederick William III on the initiative of Wilhelm von Humboldt, Johann Gottlieb Fichte and Friedrich Ernst Daniel Schleiermacher as the University of Berlin () in 1809, and opened in 1810, making it the oldest of Berlin's four universities. From 1828 until its closure in 1945, it was named Friedrich Wilhelm University (german: Friedrich-Wilhelms-Universität). During the Cold War, the university found itself in East Berlin and was ''de facto'' split in two when the Free University of Berlin opened in West Berlin. The university received its current name in honour of Alexander and Wilhelm von Humboldt in 1949. The university is divided into nine faculties including its medical school shared with the Freie Universität Berlin. The university has a student enrollment of around 32,0 ...
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Jakob Segal
Jakob Segal (17 April 1911 – 30 September 1995) was a Russian-born German biology professor at Humboldt University of Berlin in the former East Germany. He was one of the advocates of the conspiracy theory that HIV was created by the United States government at Fort Detrick, Maryland. After the fall of the Soviet Union, KGB defector Vasili Mitrokhin and two former members of East Germany's secret police revealed that Segal was a Soviet disinformation agent who worked for the KGB. Early life and education Segal was born in Saint Petersburg, Russian Empire, into a Lithuanian Jewish family, the son of Hermann Segal, a merchant from Kaunas (1880–1941), and Rebekka (''née'' Schlimakowski; 1887–1941). He had an older brother, Moshe, an electrician. When he was 8, his family moved to Königsberg, Prussia (now Kaliningrad, Russia). He was educated in Berlin and Munich, where he joined the Red Students' League (''Roter Studentenbund'') and the Communist Party of Germany. In 19 ...
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US Government
The federal government of the United States (U.S. federal government or U.S. government) is the national government of the United States, a federal republic located primarily in North America, composed of 50 states, a city within a federal district (the city of Washington in the District of Columbia, where most of the federal government is based), five major self-governing territories and several island possessions. The federal government, sometimes simply referred to as Washington, is composed of three distinct branches: legislative, executive, and judicial, whose powers are vested by the U.S. Constitution in the Congress, the president and the federal courts, respectively. The powers and duties of these branches are further defined by acts of Congress, including the creation of executive departments and courts inferior to the Supreme Court. Naming The full name of the republic is "United States of America". No other name appears in the Constitution, and this is t ...
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Nature (journal)
''Nature'' is a British weekly scientific journal founded and based in London, England. As a multidisciplinary publication, ''Nature'' features peer-reviewed research from a variety of academic disciplines, mainly in science and technology. It has core editorial offices across the United States, continental Europe, and Asia under the international scientific publishing company Springer Nature. ''Nature'' was one of the world's most cited scientific journals by the Science Edition of the 2019 ''Journal Citation Reports'' (with an ascribed impact factor of 42.778), making it one of the world's most-read and most prestigious academic journals. , it claimed an online readership of about three million unique readers per month. Founded in autumn 1869, ''Nature'' was first circulated by Norman Lockyer and Alexander Macmillan as a public forum for scientific innovations. The mid-20th century facilitated an editorial expansion for the journal; ''Nature'' redoubled its efforts in explan ...
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Centers For Disease Control And Prevention
The Centers for Disease Control and Prevention (CDC) is the national public health agency of the United States. It is a United States federal agency, under the Department of Health and Human Services, and is headquartered in Atlanta, Georgia. The agency's main goal is the protection of public health and safety through the control and prevention of disease, injury, and disability in the US and worldwide. The CDC focuses national attention on developing and applying disease control and prevention. It especially focuses its attention on infectious disease, food borne pathogens, environmental health, occupational safety and health, health promotion, injury prevention and educational activities designed to improve the health of United States citizens. The CDC also conducts research and provides information on non-infectious diseases, such as obesity and diabetes, and is a founding member of the International Association of National Public Health Institutes.
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Scientific Consensus
Scientific consensus is the generally held judgment, position, and opinion of the majority or the supermajority of scientists in a particular field of study at any particular time. Consensus is achieved through scholarly communication at conferences, the publication process, replication of reproducible results by others, scholarly debate, and peer review. A conference meant to create a consensus is termed as a consensus conference. Such measures lead to a situation in which those within the discipline can often recognize such a consensus where it exists; however, communicating to outsiders that consensus has been reached can be difficult, because the "normal" debates through which science progresses may appear to outsiders as contestation. On occasion, scientific institutes issue position statements intended to communicate a summary of the science from the "inside" to the "outside" of the scientific community, or consensus review articles or surveys may be published. In cases wh ...
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Phylogenetic
In biology, phylogenetics (; from Greek φυλή/ φῦλον [] "tribe, clan, race", and wikt:γενετικός, γενετικός [] "origin, source, birth") is the study of the evolutionary history and relationships among or within groups of organisms. These relationships are determined by Computational phylogenetics, phylogenetic inference methods that focus on observed heritable traits, such as DNA sequences, protein amino acid sequences, or morphology. The result of such an analysis is a phylogenetic tree—a diagram containing a hypothesis of relationships that reflects the evolutionary history of a group of organisms. The tips of a phylogenetic tree can be living taxa or fossils, and represent the "end" or the present time in an evolutionary lineage. A phylogenetic diagram can be rooted or unrooted. A rooted tree diagram indicates the hypothetical common ancestor of the tree. An unrooted tree diagram (a network) makes no assumption about the ancestral line, and does ...
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