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Antp
''Antennapedia'' (abbreviated ''Antp'') is a Hox gene first discovered in ''Drosophila'' which controls the formation of legs during development. Loss-of-function mutations in the regulatory region of this gene result in the development of the second leg pair into ectopic antennae. By contrast gain-of-function alleles convert antennae into ectopic legs. This is just one illustration of the tendency of organisms to exhibit variations on a theme: modulated repetition. Legs and antennae are related to one another as much as molars are to incisors, fingers are to toes, and arms are to legs. ''Antp'' also refers to a gene complex (ANT-C) in ''Drosophila'' ending with the ''Antp'' gene. It is responsible for formation and differentiation of the thoracic and head segments of the fly's body. Origin of ''Antennapedia''-class homeobox gene The origin of the ancestor homeobox gene is an important aspect of the evolution of the ''Antp''-class ''Hox'' genes. Early evolution of the ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Antennapedia2
''Antennapedia'' (abbreviated ''Antp'') is a Hox gene first discovered in ''Drosophila'' which controls the formation of legs during development. Loss-of-function mutations in the regulatory region of this gene result in the development of the second leg pair into ectopic antennae. By contrast gain-of-function alleles convert antennae into ectopic legs. This is just one illustration of the tendency of organisms to exhibit variations on a theme: modulated repetition. Legs and antennae are related to one another as much as molars are to incisors, fingers are to toes, and arms are to legs. ''Antp'' also refers to a gene complex (ANT-C) in ''Drosophila'' ending with the ''Antp'' gene. It is responsible for formation and differentiation of the thoracic and head segments of the fly's body. Origin of ''Antennapedia''-class homeobox gene The origin of the ancestor homeobox gene is an important aspect of the evolution of the ''Antp''-class ''Hox'' genes. Early evolution of the ' ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Hox Gene
Hox genes, a subset of homeobox, homeobox genes, are a gene cluster, group of related genes that Evolutionary developmental biology, specify regions of the body plan of an embryo along the craniocaudal axis, head-tail axis of animals. Hox proteins encode and specify the characteristics of 'position', ensuring that the correct structures form in the correct places of the body. For example, Hox genes in insects specify which appendages form on a segment (for example, legs, antennae, and wings in fruit flies), and Hox genes in vertebrates specify the types and shape of vertebrae that will form. In segmented animals, Hox proteins thus confer segmental or positional identity, but do not form the actual segments themselves. Studies on Hox genes in ciliated larvae have shown they are only expressed in future adult tissues. In larvae with gradual metamorphosis the Hox genes are activated in tissues of the larval body, generally in the trunk region, that will be maintained through metamorp ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Homeobox Gene
A homeobox is a DNA sequence, around 180 base pairs long, that regulates large-scale anatomical features in the early stages of embryonic development. Mutations in a homeobox may change large-scale anatomical features of the full-grown organism. Homeoboxes are found within genes that are involved in the regulation of patterns of anatomical development (morphogenesis) in animals, fungi, plants, and numerous single cell eukaryotes. Homeobox genes encode homeodomain protein products that are transcription factors sharing a characteristic protein fold structure that binds DNA to regulate expression of target genes. Homeodomain proteins regulate gene expression and cell differentiation during early embryonic development, thus mutations in homeobox genes can cause developmental disorders. Homeosis is a term coined by William Bateson to describe the outright replacement of a discrete body part with another body part, e.g. antennapedia—replacement of the antenna on the head of a fr ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Gastrulation
Gastrulation is the stage in the early embryonic development of most animals, during which the blastula (a single-layered hollow sphere of cells), or in mammals, the blastocyst, is reorganized into a two-layered or three-layered embryo known as the gastrula. Before gastrulation, the embryo is a continuous epithelial sheet of cells; by the end of gastrulation, the embryo has begun differentiation to establish distinct cell lineages, set up the basic axes of the body (e.g. dorsal–ventral, anterior–posterior), and internalized one or more cell types, including the prospective gut. Gastrula layers In triploblastic organisms, the gastrula is trilaminar (three-layered). These three germ layers are the ectoderm (outer layer), mesoderm (middle layer), and endoderm (inner layer).Mundlos 2009p. 422/ref>McGeady, 2004: p. 34 In diploblastic organisms, such as Cnidaria and Ctenophora, the gastrula has only ectoderm and endoderm. The two layers are also sometimes referred to as ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Xenopus
''Xenopus'' () (Gk., ξενος, ''xenos'' = strange, πους, ''pous'' = foot, commonly known as the clawed frog) is a genus of highly aquatic frogs native to sub-Saharan Africa. Twenty species are currently described within it. The two best-known species of this genus are '' Xenopus laevis'' and '' Xenopus tropicalis'', which are commonly studied as model organisms for developmental biology, cell biology, toxicology, neuroscience and for modelling human disease and birth defects. The genus is also known for its polyploidy, with some species having up to 12 sets of chromosomes. Characteristics ''Xenopus laevis'' is a rather inactive creature. It is incredibly hardy and can live up to 15 years. At times the ponds that ''Xenopus laevis'' is found in dry up, compelling it, in the dry season, to burrow into the mud, leaving a tunnel for air. It may lie dormant for up to a year. If the pond dries up in the rainy season, ''Xenopus laevis'' may migrate long di ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Transcription (genetics)
Transcription is the process of copying a segment of DNA into RNA for the purpose of gene expression. Some segments of DNA are transcribed into RNA molecules that can encode proteins, called messenger RNA (mRNA). Other segments of DNA are transcribed into RNA molecules called non-coding RNAs (ncRNAs). Both DNA and RNA are nucleic acids, which use base pairs of nucleotides as a complementary language. During transcription, a DNA sequence is read by an RNA polymerase, which produces a complementary, antiparallel RNA strand called a primary transcript. In virology, the term transcription is used when referring to mRNA synthesis from a viral RNA molecule. The genome of many RNA viruses is composed of negative-sense RNA which acts as a template for positive sense viral messenger RNA - a necessary step in the synthesis of viral proteins needed for viral replication. This process is catalyzed by a viral RNA dependent RNA polymerase. Background A DNA transcription unit encoding ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Parasteatoda Tepidariorum
''Parasteatoda tepidariorum'', the common house spider or American house spider, is a spider species of the genus ''Parasteatoda'' with a cosmopolitan distribution. Common house spiders are synanthrope, synanthropic and live in and near human dwellings. Their prey mechanism is similar to that of the other cobweb spiders: the spider follows disturbances transmitted along the web to entangle and then paralyze its prey, which usually consists of household insects and other invertebrates (often considered as pest (organism), pests). Description Appearance Common house spiders are variable in color from tan to nearly black, frequently with patterns of differing shades on their body. Females are generally between long, and males are generally between long. They can be an inch (2.5 cm) or more across with legs outspread. The average female body mass is about 37.7 mg. ''P. tepidariorum'' is similar in body shape to widow spiders. Males have a less bulbous abdomen than females. C ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Down-regulation
In biochemistry, in the biological context of organisms' regulation of gene expression and production of gene products, downregulation is the process by which a cell decreases the production and quantities of its cellular components, such as RNA and proteins, in response to an external stimulus. The complementary process that involves increase in quantities of cellular components is called upregulation. An example of downregulation is the cellular decrease in the expression of a specific receptor in response to its increased activation by a molecule, such as a hormone or neurotransmitter, which reduces the cell's sensitivity to the molecule. This is an example of a locally acting (negative feedback) mechanism. An example of upregulation is the response of liver cells exposed to such xenobiotic molecules as dioxin. In this situation, the cells increase their production of cytochrome P450 enzymes, which in turn increases degradation of these dioxin molecules. Downregulation or ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Metazoan
Animals are multicellular, eukaryotic organisms in the biological kingdom Animalia (). With few exceptions, animals consume organic material, breathe oxygen, have myocytes and are able to move, can reproduce sexually, and grow from a hollow sphere of cells, the blastula, during embryonic development. Animals form a clade, meaning that they arose from a single common ancestor. Over 1.5 million living animal species have been described, of which around 1.05 million are insects, over 85,000 are molluscs, and around 65,000 are vertebrates. It has been estimated there are as many as 7.77 million animal species on Earth. Animal body lengths range from to . They have complex ecologies and interactions with each other and their environments, forming intricate food webs. The scientific study of animals is known as zoology, and the study of animal behaviour is known as ethology. The animal kingdom is divided into five major clades, namely Porifera, Ctenophora, Placozoa, ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Cnidaria
Cnidaria ( ) is a phylum under kingdom Animalia containing over 11,000 species of aquatic invertebrates found both in fresh water, freshwater and marine environments (predominantly the latter), including jellyfish, hydroid (zoology), hydroids, sea anemones, corals and some of the smallest marine parasites. Their distinguishing features are an uncentralized nervous system distributed throughout a gelatinous body and the presence of cnidocytes or cnidoblasts, specialized cells with ejectable flagella used mainly for envenomation and capturing prey. Their bodies consist of mesoglea, a non-living, jelly-like substance, sandwiched between two layers of epithelium that are mostly one cell (biology), cell thick. Cnidarians are also some of the few animals that can reproduce both sexually and asexually. Cnidarians mostly have two basic body forms: swimming medusa (biology), medusae and sessility (motility), sessile polyp (zoology), polyps, both of which are radially symmetrical with mou ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Thorax (insect Anatomy)
The thorax is the midsection ( tagma) of the hexapod body (insects and entognathans). It holds the head, legs, wings and abdomen. It is also called mesosoma or cephalothorax in other arthropods. It is formed by the prothorax, mesothorax and metathorax and comprises the scutellum; the cervix, a membrane that separates the head from the thorax; and the pleuron, a lateral sclerite of the thorax. In dragonflies and damselflies, the mesothorax and metathorax are fused together to form the synthorax. In some insect pupae, like the mosquitoes', the head and thorax can be fused in a cephalothorax. Members of suborder Apocrita (wasps, ants and bees) in the order Hymenoptera have the first segment of the abdomen fused with the thorax, which is called the propodeum. The head is connected to the thorax by the occipital foramen, enabling a wide range of motion for the head. In most flying insects, the thorax allows for the use of asynchronous muscles Asynchronous muscles are muscle ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
