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Adrenal Gland Disorder
Adrenal gland disorders (or diseases) are conditions that interfere with the normal functioning of the adrenal glands. Adrenal disorders may cause hyperfunction or hypofunction, and may be congenital or acquired. The adrenal gland produces hormones that affects growth, development and stress, and also helps to regulate kidney function. There are two parts of the adrenal glands, the adrenal cortex and the adrenal medulla. The adrenal cortex produces mineralocorticoids, which regulate salt and water balance within the body, glucocorticoids (including cortisol) which have a wide number of roles within the body, and androgens, hormones with testosterone-like function.Adrenal Glands Johns Hopkins Medicine Health Library. The |
Adrenal Gland
The adrenal glands (also known as suprarenal glands) are endocrine glands that produce a variety of hormones including adrenaline and the steroids aldosterone and cortisol. They are found above the kidneys. Each gland has an outer cortex which produces steroid hormones and an inner medulla. The adrenal cortex itself is divided into three main zones: the zona glomerulosa, the zona fasciculata and the zona reticularis. The adrenal cortex produces three main types of steroid hormones: mineralocorticoids, glucocorticoids, and androgens. Mineralocorticoids (such as aldosterone) produced in the zona glomerulosa help in the regulation of blood pressure and electrolyte balance. The glucocorticoids cortisol and cortisone are synthesized in the zona fasciculata; their functions include the regulation of metabolism and immune system suppression. The innermost layer of the cortex, the zona reticularis, produces androgens that are converted to fully functional sex hormones in the gonads ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Multiple Endocrine Neoplasia
Multiple endocrine neoplasia (abbreviated MEN) is a condition which encompasses several distinct syndromes featuring tumors of endocrine glands, each with its own characteristic pattern. In some cases, the tumors are malignant, in others, benign. Benign or malignant tumors of nonendocrine tissues occur as components of some of these tumor syndromes. MEN syndromes are inherited as autosomal dominant disorders. Presentation Related conditions Although not officially categorized as multiple endocrine neoplasia syndromes, Von Hippel–Lindau disease and Carney complex are two other autosomal dominant endocrine tumor syndromes with features that overlap the clinical features of the MEN syndromes. Although not transmitted in the germline, McCune–Albright syndrome is a genetic disorder characterized by endocrine neoplastic features involving endocrine glands that overlap with those involved in MEN1 or MEN2. Comparison Percentages in the table below refer to the percentage of peopl ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Adrenal Crisis
Adrenal crisis is a potentially life-threatening medical condition requiring immediate emergency treatment. It is a constellation of symptoms (caused by insufficient levels of the hormone cortisol) that indicate severe adrenal insufficiency. This may be the result of either previously undiagnosed or untreated Addison's disease, a disease process suddenly affecting adrenal function (such as bleeding from the adrenal glands in Waterhouse–Friderichsen syndrome), suddenly stopping intake of glucocorticoids or an intercurrent problem (e.g. infection, trauma, in fact any form of physical or mental stress) in someone known to have Addison's disease, congenital adrenal hyperplasia (CAH), or other form of primary adrenal insufficiency. Signs and symptoms Characteristic symptoms are: * Sudden penetrating pain in the legs, lower back or abdomen * Confusion, psychosis, slurred speech * Severe lethargy * Convulsions * Fever * Hyperkalemia (elevated potassium level in the blood) * Hypercalcemi ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Mineralocorticoids
Mineralocorticoids are a class of corticosteroids, which in turn are a class of steroid hormones. Mineralocorticoids are produced in the adrenal cortex and influence salt and water balances (electrolyte balance and fluid balance). The primary mineralocorticoid is aldosterone. Physiology The name mineralocorticoid derives from early observations that these hormones were involved in the retention of sodium, a mineral. The primary endogenous mineralocorticoid is aldosterone, although a number of other endogenous hormones (including progesterone and deoxycorticosterone) have mineralocorticoid function. Aldosterone acts on the kidneys to provide active reabsorption of sodium and an associated passive reabsorption of water, as well as the active secretion of potassium in the principal cells of the cortical collecting tubule and active secretion of protons via proton ATPases in the lumenal membrane of the intercalated cells of the collecting tubule. This in turn results in an increase ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Glucocorticoids
Glucocorticoids (or, less commonly, glucocorticosteroids) are a class of corticosteroids, which are a class of steroid hormones. Glucocorticoids are corticosteroids that bind to the glucocorticoid receptor that is present in almost every vertebrate animal cell. The name "glucocorticoid" is a portmanteau (glucose + cortex + steroid) and is composed from its role in regulation of glucose metabolism, synthesis in the adrenal cortex, and its steroidal structure (see structure below). Glucocorticoids are part of the feedback mechanism in the immune system, which reduces certain aspects of immune function, such as inflammation. They are therefore used in medicine to treat diseases caused by an overactive immune system, such as allergies, asthma, autoimmune diseases, and sepsis. Glucocorticoids have many diverse (pleiotropic) effects, including potentially harmful side effects. They also interfere with some of the abnormal mechanisms in cancer cells, so they are used in high doses to tr ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Addison's Disease
Addison's disease, also known as primary adrenal insufficiency, is a rare long-term endocrine disorder characterized by inadequate production of the steroid hormones cortisol and aldosterone by the two outer layers of the cells of the adrenal glands (adrenal cortex), causing adrenal insufficiency. Symptoms generally come on slowly and insidiously and may include abdominal pain and gastrointestinal abnormalities, weakness, and weight loss. Darkening of the skin in certain areas may also occur. Under certain circumstances, an adrenal crisis may occur with low blood pressure, vomiting, lower back pain, and loss of consciousness. Mood changes may also occur. Rapid onset of symptoms indicates acute adrenal failure which is a serious and emergent condition. An adrenal crisis can be triggered by stress, such as from an injury, surgery, or infection. Addison's disease arises from problems with the adrenal gland such that not enough of the steroid hormone cortisol and possibly aldo ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Jet Propulsion Laboratory
The Jet Propulsion Laboratory (JPL) is a federally funded research and development center and NASA field center in the City of La Cañada Flintridge, California, United States. Founded in the 1930s by Caltech researchers, JPL is owned by NASA and managed by the nearby California Institute of Technology (Caltech). The laboratory's primary function is the construction and operation of planetary robotic spacecraft, though it also conducts Earth-orbit and astronomy missions. It is also responsible for operating the NASA Deep Space Network. Among the laboratory's major active projects are the Mars 2020 mission, which includes the ''Perseverance'' rover and the '' Ingenuity'' Mars helicopter; the Mars Science Laboratory mission, including the ''Curiosity'' rover; the InSight lander (''Interior Exploration using Seismic Investigations, Geodesy and Heat Transport''); the ''Mars Reconnaissance Orbiter''; the ''Juno'' spacecraft orbiting Jupiter; the ''SMAP'' satellite for earth surface s ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Comet Shoemaker-Levy 9
A comet is an icy, small Solar System body that, when passing close to the Sun, warms and begins to release gases, a process that is called outgassing. This produces a visible atmosphere or coma, and sometimes also a tail. These phenomena are due to the effects of solar radiation and the solar wind acting upon the nucleus of the comet. Comet nuclei range from a few hundred meters to tens of kilometers across and are composed of loose collections of ice, dust, and small rocky particles. The coma may be up to 15 times Earth's diameter, while the tail may stretch beyond one astronomical unit. If sufficiently bright, a comet may be seen from Earth without the aid of a telescope and may subtend an arc of 30° (60 Moons) across the sky. Comets have been observed and recorded since ancient times by many cultures and religions. Comets usually have highly eccentric elliptical orbits, and they have a wide range of orbital periods, ranging from several years to potentially several mil ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Eugene Merle Shoemaker
Eugene Merle Shoemaker (April 28, 1928 – July 18, 1997) was an American geologist. He co-discovered Comet Shoemaker–Levy 9 with his wife Carolyn S. Shoemaker and David H. Levy. This comet hit Jupiter in July 1994: the impact was televised around the world. Shoemaker also studied terrestrial craters, such as Barringer Meteor Crater in Arizona, and along with Edward Chao provided the first conclusive evidence of its origin as an impact crater. He was also the first director of the United States Geological Survey's Astrogeology Research Program. He was killed in a car accident while visiting an impact crater site in Australia. After his death, some of his ashes were carried to the Moon with the Lunar Prospector mission. Early life and formal education Shoemaker was born in Los Angeles, California, the son of Muriel May (née Scott), a teacher; and George Estel Shoemaker, who worked in farming, business, teaching, and motion pictures. His parents were natives of Nebraska. D ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Medical Humanities
''Medical Humanities'' is a quarterly peer-reviewed academic journal covering the field of medical humanities. The journal presents the international conversation around medicine and its engagement with the humanities and arts, social sciences, health policy, medical education, patient experience, and the public at large. Led by Dr Brandy Schillace, the journal publishes scholarly and critical articles on a broad range of topics. These include history of medicine, cultures of medicine, disability studies, gender and the body, communities in crisis, bioethics and public health. The journal is abstracted and indexed by Medline, the Arts and Humanities Citation Index, Scopus and Current Contents ''Current Contents'' is a rapid alerting service database from Clarivate Analytics, formerly the Institute for Scientific Information and Thomson Reuters. It is published online and in several different printed subject sections. History ''Cur .../Arts and Humanities. The journal was laun ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Addison's Disease
Addison's disease, also known as primary adrenal insufficiency, is a rare long-term endocrine disorder characterized by inadequate production of the steroid hormones cortisol and aldosterone by the two outer layers of the cells of the adrenal glands (adrenal cortex), causing adrenal insufficiency. Symptoms generally come on slowly and insidiously and may include abdominal pain and gastrointestinal abnormalities, weakness, and weight loss. Darkening of the skin in certain areas may also occur. Under certain circumstances, an adrenal crisis may occur with low blood pressure, vomiting, lower back pain, and loss of consciousness. Mood changes may also occur. Rapid onset of symptoms indicates acute adrenal failure which is a serious and emergent condition. An adrenal crisis can be triggered by stress, such as from an injury, surgery, or infection. Addison's disease arises from problems with the adrenal gland such that not enough of the steroid hormone cortisol and possibly aldo ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
En:avant La Lettre
Many words in the English vocabulary are of French origin, most coming from the Anglo-Norman language, Anglo-Norman spoken by the upper classes in England for several hundred years after the Norman conquest of England, Norman Conquest, before the language settled into what became Modern English. English List of English words of French origin, words of French origin, such as ''art'', ''competition'', ''force'', ''machine'', and ''table'' are pronounced according to English language, English rules of phonology, rather than French language, French, and are commonly used by English speakers without any consciousness of their French origin. This article, on the other hand, covers French words and phrases that have entered the English lexicon without ever losing their character as Gallicisms: they remain unmistakably "French" to an English speaker. They are most common in written English, where they retain French diacritics and are usually printed in italics. In spoken English, at le ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
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