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ATC Code P01
P01A Agents against amoebiasis and other protozoal diseases P01AA Hydroxyquinoline derivatives :P01AA01 Broxyquinoline :P01AA02 Clioquinol :P01AA04 Chlorquinaldol :P01AA05 Tilbroquinol :P01AA30 Tilbroquinol and tiliquinol :P01AA52 Clioquinol, combinations P01AB Nitroimidazole derivatives :P01AB01 Metronidazole :P01AB02 Tinidazole :P01AB03 Ornidazole :P01AB04 Azanidazole :P01AB05 Propenidazole :P01AB06 Nimorazole :P01AB07 Secnidazole :P01AB51 Metronidazole and furazolidone :P01AB52 Metronidazole and diloxanide P01AC Dichloroacetamide derivatives :P01AC01 Diloxanide :P01AC02 Clefamide :P01AC03 Etofamide :P01AC04 Teclozan P01AR Arsenic compounds :P01AR01 Arsthinol :P01AR02 Difetarsone :P01AR03 Glycobiarsol :P01AR53 Glycobiarsol, combinations P01AX Other agents against amoebiasis and other protozoal diseases :P01AX01 Chiniofon :P01AX02 Emetine :P01AX04 Phanquinone :P01AX05 Mepacrine :P01AX06 Atovaquone :P01AX07 Trimetrexate :P01AX08 Tenonitrozole :P01AX09 Dehydroemetine :P01AX10 Fum ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Amoebiasis
Amoebiasis, or amoebic dysentery, is an infection of the intestines caused by a parasitic amoeba ''Entamoeba histolytica''. Amoebiasis can be present with no, mild, or severe symptoms. Symptoms may include lethargy, loss of weight, colonic ulcerations, abdominal pain, diarrhea, or bloody diarrhea. Complications can include inflammation and ulceration of the colon with tissue death or perforation, which may result in peritonitis. Anemia may develop due to prolonged gastric bleeding. Cysts of ''Entamoeba'' can survive for up to a month in soil or for up to 45 minutes under fingernails. Invasion of the intestinal lining results in bloody diarrhea. If the parasite reaches the bloodstream it can spread through the body, most frequently ending up in the liver where it can cause amoebic liver abscesses. Liver abscesses can occur without previous diarrhea. Diagnosis is typically made by stool examination using microscopy, but it can be difficult to distinguish ''E. hystolitica'' fro ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Diloxanide
Diloxanide is a medication used to treat amebiasis, amoeba infections. In places where infections are not common, it is a second line treatment after paromomycin when a person has no symptoms. For people who are symptomatic, it is used after treatment with metronidazole or tinidazole. It is taken Oral administration, by mouth. Diloxanide generally has mild side effects. Side effects may include flatulence, vomiting, and itchiness. During pregnancy it is recommended that it be taken after the first trimester. It is a Amebicide#Luminal amebicides, luminal amebicide meaning that it only works on infections within the intestines. Diloxanide came into medical use in 1956. It is on the WHO Model List of Essential Medicines, World Health Organization's List of Essential Medicines. It is not commercially available in much of the developed world as of 2012. Medical uses Diloxanide furoate works only in the digestive tract and is a Amebicide#Lumenal amebicides, lumenal amebicide. It ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Mepacrine
Mepacrine, also called quinacrine or by the trade name Atabrine, is a medication with several uses. It is related to chloroquine and mefloquine. Although formerly available from compounding pharmacies, as of August 2020 it is unavailable in the United States. Medical uses The main uses of mepacrine are as an antiprotozoal, antirheumatic, and an intrapleural sclerosing agent. Possible reasons for the lack of an ''in vivo effect'' include inefficient penetration of the blood–brain barrier, as well as the existence of drug-resistant prion proteins that increase in number when selected for by treatment with mepacrine. Non-surgical sterilization for women The use of mepacrine for non-surgical sterilization for women has also been studied. The first report of this method claimed a first year failure rate of 3.1%. However, despite a multitude of clinical studies on the use of mepacrine and female sterilization, no randomized, controlled trials have been reported to date and ther ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Phanquinone
Phanquinone is an organic compound. It is a yellowish solid derived by oxidation of 4,7-phenanthroline. It has been investigated as both antiprotozoal agent Antiprotozoal agents ( ATC code: ATC P01) is a class of pharmaceuticals used in treatment of protozoan infection. A paraphyletic group, protozoans have little in common with each other. For example, '' Entamoeba histolytica'', a unikont eukary ... and for its bactericidal activity . References Antiprotozoal agents Phenanthrolines Quinones Bipyridines Enones {{antiinfective-drug-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Emetine
Emetine is a drug used as both an anti-protozoal and to induce vomiting. It is produced from the ipecac root. It takes its name from its emetic properties. Early preparations Mechanism of action of emetine was studied by François Magendie during the nineteenth century. Early use of emetine was in the form of oral administration of the extract of ipecac root, or ipecacuanha. This extract was originally thought to contain only one alkaloid, emetine, but was found to contain several, including cephaeline, psychotrine and others. Although this therapy was reportedly successful, the extract caused vomiting in many patients, which reduced its utility. In some cases, it was given with opioids to reduce nausea. Other approaches to reduce nausea involved coated tablets, allowing the drug to be released after digestion in the stomach. Use as anti-amoebic The identification of emetine as a more potent agent improved the treatment of amoebiasis. While use of emetine still caused nausea ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Chiniofon
Chiniofon is an antiprotozoal agent Antiprotozoal agents ( ATC code: ATC P01) is a class of pharmaceuticals used in treatment of protozoan infection. A paraphyletic group, protozoans have little in common with each other. For example, '' Entamoeba histolytica'', a unikont eukary .... References Further reading * Sulfonic acids Quinolinols Iodoarenes Antiprotozoal agents {{antiinfective-drug-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Glycobiarsol
Glycobiarsol (trade name Milibis) is an antiprotozoal agent Antiprotozoal agents ( ATC code: ATC P01) is a class of pharmaceuticals used in treatment of protozoan infection. A paraphyletic group, protozoans have little in common with each other. For example, '' Entamoeba histolytica'', a unikont eukary ... that has been used in humans as well as in dogs. References Antiprotozoal agents Organoarsenic compounds Bismuth compounds Acetanilides {{Antiinfective-drug-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Difetarsone
Difetarsone is an antiprotozoal agent. Various studies have shown it to be particularly effective against ''Trichuris trichiura'', commonly known as the whipworm. Prior to the drugs use in the early 1970s, there were few effective treatments for this infection. It has also been used to treat Entamoeba histolytica infections. Difetarsone often has minor side effects, which include rashes, nausea and vomiting. It has also resulted in angioedema Angioedema is an area of swelling (edema) of the lower layer of skin and tissue just under the skin or mucous membranes. The swelling may occur in the face, tongue, larynx, abdomen, or arms and legs. Often it is associated with hives, which ar ... in at least one known case. References Antiprotozoal agents Arsonic acids {{Antiinfective-drug-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Arsthinol
Arsthinol (INN) is an antiprotozoal agent. It was synthesized for the first time in 1949 by Ernst A.H. Friedheim by complexation of acetarsol with 2,3-dimercaptopropanol (British anti-Lewisite) and has been demonstrated to be effective against amoebiasis and yaws Yaws is a tropical infection of the skin, bones, and joints caused by the spirochete bacterium ''Treponema pallidum pertenue''. The disease begins with a round, hard swelling of the skin, in diameter. The center may break open and form an ul .... It was marketed few years later by Endo Products (Balarsen, Tablets, 0.1 g). Among trivalent organoarsenicals, arsthinol was considered as very well tolerated. Recently, it was studied for its anticancer activity. References Antiprotozoal agents Acetanilides Primary alcohols Phenols Organoarsenic dithiolates Arsenic heterocycles Arsenic(III) compounds Sulfur heterocycles Heterocyclic compounds with 1 ring {{Antimicrobial-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Arsenic
Arsenic is a chemical element with the symbol As and atomic number 33. Arsenic occurs in many minerals, usually in combination with sulfur and metals, but also as a pure elemental crystal. Arsenic is a metalloid. It has various allotropes, but only the gray form, which has a metallic appearance, is important to industry. The primary use of arsenic is in alloys of lead (for example, in car batteries and ammunition). Arsenic is a common n-type dopant in semiconductor electronic devices. It is also a component of the III-V compound semiconductor gallium arsenide. Arsenic and its compounds, especially the trioxide, are used in the production of pesticides, treated wood products, herbicides, and insecticides. These applications are declining with the increasing recognition of the toxicity of arsenic and its compounds. A few species of bacteria are able to use arsenic compounds as respiratory metabolites. Trace quantities of arsenic are an essential dietary element in rats, ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Teclozan
Teclozan is an antiprotozoal agent. It is a dichloroacetamide Dichloroacetamide is a chlorinated derivative of acetamide Acetamide (systematic name: ethanamide) is an organic compound with the formula CH3CONH2. It is the simplest amide derived from acetic acid. It finds some use as a plasticizer and as an .... References Organochlorides Antiprotozoal agents Acetamides Ethers {{antiinfective-drug-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Etofamide
Etofamide (INN, also known as eticlordifene) is an antiprotozoal drug used in the treatment of amoebiasis. Its effect against ''Giardia lamblia ''Giardia duodenalis'', also known as ''Giardia intestinalis'' and ''Giardia lamblia'', is a flagellated parasitic microorganism of the genus ''Giardia'' that colonizes the small intestine, causing a diarrheal condition known as giardiasis. The ...'' has been described as modest. References Antiprotozoal agents Nitrobenzenes Organochlorides Phenol ethers {{Antiinfective-drug-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
