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ATC Code J04
J04A Drugs for treatment of tuberculosis J04AA Aminosalicylic acid and derivatives :J04AA01 Aminosalicylic acid :J04AA02 Sodium aminosalicylate :J04AA03 Calcium aminosalicylate J04AB Antibiotics :J04AB01 Cycloserine :J04AB02 Rifampicin :J04AB03 Rifamycin :J04AB04 Rifabutin :J04AB05 Rifapentin :J04AB06 Enviomycin :J04AB30 Capreomycin J04AC Hydrazides :J04AC01 Isoniazid :J04AC51 Isoniazid, combinations J04AD Thiocarbamide derivatives :J04AD01 Protionamide :J04AD02 Tiocarlide :J04AD03 Ethionamide J04AK Other drugs for treatment of tuberculosis :J04AK01 Pyrazinamide :J04AK02 Ethambutol :J04AK03 Terizidone :J04AK04 Morinamide :J04AK05 Bedaquiline :J04AK06 Delamanid :J04AK07 Amithiozone :J04AK08 Pretomanid J04AM Combinations of drugs for treatment of tuberculosis :J04AM01 Streptomycin and isoniazid :J04AM02 Rifampicin and isoniazid :J04AM03 Ethambutol and isoniazid :J04AM04 Thioacetazone and isoniazid :J04AM05 Rifampicin, pyrazinamide and isoniazid :J04AM06 Rifampicin, ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Tuberculosis
Tuberculosis (TB) is an infectious disease usually caused by '' Mycobacterium tuberculosis'' (MTB) bacteria. Tuberculosis generally affects the lungs, but it can also affect other parts of the body. Most infections show no symptoms, in which case it is known as latent tuberculosis. Around 10% of latent infections progress to active disease which, if left untreated, kill about half of those affected. Typical symptoms of active TB are chronic cough with blood-containing mucus, fever, night sweats, and weight loss. It was historically referred to as consumption due to the weight loss associated with the disease. Infection of other organs can cause a wide range of symptoms. Tuberculosis is spread from one person to the next through the air when people who have active TB in their lungs cough, spit, speak, or sneeze. People with Latent TB do not spread the disease. Active infection occurs more often in people with HIV/AIDS and in those who smoke. Diagnosis of active TB is ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Pyrazinamide
Pyrazinamide is a medication used to treat tuberculosis. For active tuberculosis, it is often used with rifampicin, isoniazid, and either streptomycin or ethambutol. It is not generally recommended for the treatment of latent tuberculosis. It is taken by mouth. Common side effects include nausea, loss of appetite, muscle and joint pains, and rash. More serious side effects include gout, liver toxicity, and sensitivity to sunlight. It is not recommended in those with significant liver disease or porphyria. It is unclear if use during pregnancy is safe but it is likely okay during breastfeeding. Pyrazinamide is in the antimycobacterial class of medications. How it works is not entirely clear. Pyrazinamide was first made in 1936, but did not come into wide use until 1972. It is on the World Health Organization's List of Essential Medicines. Pyrazinamide is available as a generic medication. Medical uses Pyrazinamide is only used in combination with other drugs such as isonia ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Rifampicin/pyrazinamide/ethambutol/isoniazid
Ethambutol/isoniazid/pyrazinamide/rifampicin, also known as ethambutol/isoniazid/pyrazinamide/rifampin, is a medication used for tuberculosis. It is a fixed dose combination of ethambutol, isoniazid, pyrazinamide, and rifampicin. It is used either alone or with other antituberculosis medication. It is taken by mouth. Side effects are those of the underlying medications. Pyridoxine may be used to decrease the risk of numbness. It is not recommended in people with liver problems or severe kidney problems. Use may not be suitable in children. It is unclear if use during pregnancy Pregnancy is the time during which one or more offspring develops ( gestates) inside a woman's uterus (womb). A multiple pregnancy involves more than one offspring, such as with twins. Pregnancy usually occurs by sexual intercourse, but ca ... is safe. It is on the World Health Organization's List of Essential Medicines. It is sold under the brand names Voractiv and Rimstar in the UK. Re ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Rifampicin/isoniazid/pyrazinamide
Rifampicin/isoniazid/pyrazinamide, also known as rifampin/isoniazid/pyrazinamide, and sold under the trade name Rifater, is a medication used to treat tuberculosis. It is a fixed dose combination of rifampicin, isoniazid, and pyrazinamide. It is used either by itself or along with other antituberculosis medication. It is taken by mouth. Side effects are those of the underlying medications. These may include poor coordination, loss of appetite, nausea, joint pain, feeling tired, and numbness. Severe side effects include liver problems. Use in those under the age of 15 may not be appropriate. It is unclear if use in pregnancy is safe for the baby. Rifampicin/isoniazid/pyrazinamide was approved for medical use in the United States in 1994. It is on the World Health Organization's List of Essential Medicines. Medical uses The hope of a fixed-dose combination pill is to increase the likelihood that people will take all of three medications. Also, if people forget to take one o ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Thioacetazone
Thioacetazone (International Nonproprietary Name, INN, British Approved Name, BAN), also known as amithiozone (United States Adopted Name, USAN), is an oral administration, oral antibiotic which is used in the treatment of tuberculosis. It has fallen into almost complete disuse due to toxicity and the introduction of improved Tuberculosis management#Drugs, anti-tuberculosis drugs like isoniazid. The drug has only weak activity against ''Mycobacterium tuberculosis'' and is only useful in preventing resistance to more powerful drugs such as isoniazid and rifampicin. It is never used on its own to treat tuberculosis; it is used in a similar way to ethambutol. There is no advantage to using thioacetazone if the regimen used already contains ethambutol, but many countries in sub-Saharan Africa still use thioacetazone because it is extremely cheap. Use of thioacetazone is declining because it can cause severe (sometimes fatal) skin reactions in HIV positive patients. The biological t ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Ethambutol/isoniazid
Ethambutol/isoniazid is a fixed-dose combination medication used to treat tuberculosis. It is a fixed dose combination of ethambutol and isoniazid. It is used along with other antituberculosis medication. It is taken by mouth. Side effects are those of the underlying medications. More common side effects include poor coordination, numbness, and liver problems. Liver problems may be severe and are more likely in people over the age of 50. Use is not recommended in children. It is unclear if use in pregnancy is safe for the baby. It was removed from the World Health Organization's List of Essential Medicines The WHO Model List of Essential Medicines (aka Essential Medicines List or EML), published by the World Health Organization (WHO), contains the medications considered to be most effective and safe to meet the most important needs in a health s ... in 2019. The combination product is not available in Canada or in the United States. References Anti-tuberculosis ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Rifampicin/isoniazid
Isoniazid/rifampicin, also known as isoniazid/rifampin, is a medication used to treat tuberculosis. It is a fixed dose combination of isoniazid and rifampicin (rifampin). It is used together with other antituberculosis medication Tuberculosis management describes the techniques and procedures utilized for treating tuberculosis (TB). The medical standard for active TB is a short course treatment involving a combination of isoniazid, rifampicin (also known as Rifampin), p .... It is taken by mouth. It is on the World Health Organization's List of Essential Medicines. Adverse effects and safety Side effects are those of the underlying medications. Common side effects include poor coordination, poor appetite, nausea, numbness, and feeling tired. More severe side effects include liver problems. Use is generally not recommended in children. It is unclear if use is safe in pregnancy. References {{DEFAULTSORT:Isoniazid Rifampicin Wikipedia medicine articles ready to trans ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Pretomanid
Pretomanid is an antibiotic medication used for the treatment of multi-drug-resistant tuberculosis affecting the lungs. It is generally used together with bedaquiline and linezolid. It is taken by mouth. The most common side effects include nerve damage, acne, vomiting, headache, low blood sugar, diarrhea, and liver inflammation. It is in the nitroimidazole class of medications. Pretomanid was approved for medical use in the United States in August 2019, and in the European Union in July 2020. Text was copied from this source which is © European Medicines Agency. Reproduction is authorized provided the source is acknowledged. Pretomanid was developed by TB Alliance. The U.S. Food and Drug Administration (FDA) considers it to be a first-in-class medication. Medical uses Pretomanid is indicated in combination with bedaquiline and linezolid, in adults, for the treatment of pulmonary extensively drug resistant (XDR), or treatment-intolerant or nonresponsive multidrug-resist ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Amithiozone
Thioacetazone (INN, BAN), also known as amithiozone ( USAN), is an oral antibiotic which is used in the treatment of tuberculosis. It has fallen into almost complete disuse due to toxicity and the introduction of improved anti-tuberculosis drugs like isoniazid. The drug has only weak activity against ''Mycobacterium tuberculosis'' and is only useful in preventing resistance to more powerful drugs such as isoniazid and rifampicin. It is never used on its own to treat tuberculosis; it is used in a similar way to ethambutol. There is no advantage to using thioacetazone if the regimen used already contains ethambutol, but many countries in sub-Saharan Africa still use thioacetazone because it is extremely cheap. Use of thioacetazone is declining because it can cause severe (sometimes fatal) skin reactions in HIV positive patients. The biological target of thioacetazone has proven elusive and its mechanism of action remains unknown, although it is thought to interfere with myc ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Delamanid
Delamanid, sold under the brand name Deltyba, is a medication used to treat tuberculosis. Specifically it is used, along with other antituberculosis medications, for active multidrug-resistant tuberculosis. It is taken by mouth. Common side effects include headache, dizziness, and nausea. Other side effects include QT prolongation. It has not been studied in pregnancy as of 2016. Delamanid works by blocking the manufacture of mycolic acids thus destabilising the bacterial cell wall. It is in the nitroimidazole class of medications. Delamanid was approved for medical use in 2014 in Europe, Japan, and South Korea. It is on the World Health Organization's List of Essential Medicines. As of 2016 the Stop TB Partnership had an agreement to get the medication for US$1,700 per six month for use in more than 100 countries. Medical uses Delamanid is used, along with other antituberculosis medications, for active multidrug-resistant tuberculosis. Adverse effects Common side effects incl ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Bedaquiline
Bedaquiline, sold under the brand name Sirturo, is a medication used to treat active tuberculosis. Specifically, it is used to treat multi-drug-resistant tuberculosis (MDR-TB) along with other medications for tuberculosis. It is used by mouth. Common side effects include nausea, joint pains, headaches, and chest pain. Serious side effects include QT prolongation, liver dysfunction, and an increased risk of death. While harm during pregnancy has not been found, it has not been well studied in this population. It is in the diarylquinoline antimycobacterial class of medications. It works by blocking the ability of '' M. tuberculosis'' to make adenosine 5'-triphosphate (ATP). Bedaquiline was approved for medical use in the United States in 2012. It is on the World Health Organization's List of Essential Medicines. The cost for six months is approximately US$900 in low-income countries, US$3,000 in middle-income countries, and US$30,000 in high-income countries. The public sect ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
