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ACELL (other)
ACell is a Columbia, Maryland-based biotechnology company. The company works in regenerative medicine, in which it owns several extracellular matrix patents. ACell develops, manufactures and markets products for medical and veterinary applications. The company was founded by Alan R. Spievack, a former associate professor at Harvard Medical School and is currently run by Patrick A. McBrayer. ACell's extracellular matrix (ECM) is derived from the lamina propria and basement membrane of a porcine Urinary Bladder Matrix (UBM). The lamina propria acts as a scaffold for cell infiltration while the basement membrane encourages the growth of site-specific tissue as the UBM resorbs. The UBM is offered in both sheet and powder form. The powder form is sold under the brand name of MicroMatrix. The company offers products for wound management (Cytal and MicroMatrix), hernia repair (Gentrix) and Pelvic Organ Prolapse repair (Pelvic Floor Matrix). Over 100 papers have been published related to ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Jessup, Maryland
Jessup ( ) is an unincorporated community and census-designated place in Howard and Anne Arundel counties, about southwest of Baltimore, Maryland, United States. Per the 2020 census, the population was 10,535. Geography Jessup is located at (39.138374, −76.774929). According to the United States Census Bureau, the CDP has a total area of , all land. As of the 2010 census, the center of population for the state of Maryland is located on the grounds of the Clifton T. Perkins Hospital Center in Jessup. History Jessup is located near the site of the historic Spurrier's Tavern, a farm and tavern located on the post road between Baltimore and Washington (Route One) where George Washington traveled regularly. The location of the town was named Pierceland on early maps, but the post-civil war name more commonly given was Jessup's Cut, or Jessop's Cut, a post village in Howard County on the Baltimore and Ohio Railroad. The name is generally attributed to Jonathan Jessup, a civil ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Biotechnology
Biotechnology is the integration of natural sciences and engineering sciences in order to achieve the application of organisms, cells, parts thereof and molecular analogues for products and services. The term ''biotechnology'' was first used by Károly Ereky in 1919, meaning the production of products from raw materials with the aid of living organisms. Definition The concept of biotechnology encompasses a wide range of procedures for modifying living organisms according to human purposes, going back to domestication of animals, cultivation of the plants, and "improvements" to these through breeding programs that employ artificial selection and hybridization. Modern usage also includes genetic engineering as well as cell and tissue culture technologies. The American Chemical Society defines biotechnology as the application of biological organisms, systems, or processes by various industries to learning about the science of life and the improvement of the value of materials ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Regenerative Medicine
Regenerative medicine deals with the "process of replacing, engineering or regenerating human or animal cells, tissues or organs to restore or establish normal function". This field holds the promise of engineering damaged tissues and organs by stimulating the body's own repair mechanisms to functionally heal previously irreparable tissues or organs. Regenerative medicine also includes the possibility of growing tissues and organs in the laboratory and implanting them when the body cannot heal itself. When the cell source for a regenerated organ is derived from the patient's own tissue or cells, the challenge of organ transplant rejection via immunological mismatch is circumvented. This approach could alleviate the problem of the shortage of organs available for donation. Some of the biomedical approaches within the field of regenerative medicine may involve the use of stem cells. Examples include the injection of stem cells or progenitor cells obtained through directed differenti ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Extracellular Matrix
In biology, the extracellular matrix (ECM), also called intercellular matrix, is a three-dimensional network consisting of extracellular macromolecules and minerals, such as collagen, enzymes, glycoproteins and hydroxyapatite that provide structural and biochemical support to surrounding cells. Because multicellularity evolved independently in different multicellular lineages, the composition of ECM varies between multicellular structures; however, cell adhesion, cell-to-cell communication and differentiation are common functions of the ECM. The animal extracellular matrix includes the interstitial matrix and the basement membrane. Interstitial matrix is present between various animal cells (i.e., in the intercellular spaces). Gels of polysaccharides and fibrous proteins fill the Interstitial fluid, interstitial space and act as a compression buffer against the stress placed on the ECM. Basement membranes are sheet-like depositions of ECM on which various epithelial cells rest ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Patent
A patent is a type of intellectual property that gives its owner the legal right to exclude others from making, using, or selling an invention for a limited period of time in exchange for publishing an enabling disclosure of the invention."A patent is not the grant of a right to make or use or sell. It does not, directly or indirectly, imply any such right. It grants only the right to exclude others. The supposition that a right to make is created by the patent grant is obviously inconsistent with the established distinctions between generic and specific patents, and with the well-known fact that a very considerable portion of the patents granted are in a field covered by a former relatively generic or basic patent, are tributary to such earlier patent, and cannot be practiced unless by license thereunder." – ''Herman v. Youngstown Car Mfg. Co.'', 191 F. 579, 584–85, 112 CCA 185 (6th Cir. 1911) In most countries, patent rights fall under private law and the patent holder mus ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Harvard Medical School
Harvard Medical School (HMS) is the graduate medical school of Harvard University and is located in the Longwood Medical Area of Boston, Massachusetts. Founded in 1782, HMS is one of the oldest medical schools in the United States and is consistently ranked first for research among medical schools by '' U.S. News & World Report''. Unlike most other leading medical schools, HMS does not operate in conjunction with a single hospital but is directly affiliated with several teaching hospitals in the Boston area. Affiliated teaching hospitals and research institutes include Dana–Farber Cancer Institute, Massachusetts General Hospital, Brigham and Women's Hospital, Beth Israel Deaconess Medical Center, Boston Children's Hospital, McLean Hospital, Cambridge Health Alliance, The Baker Center for Children and Families, and Spaulding Rehabilitation Hospital. History Harvard Medical School was founded on September 19, 1782, after President Joseph Willard presented a report with ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Lamina Propria
The lamina propria is a thin layer of connective tissue that forms part of the moist linings known as mucous membranes or mucosae, which line various tubes in the body, such as the respiratory tract, the gastrointestinal tract, and the urogenital tract. The lamina propria is a thin layer of loose (areolar) connective tissue, which lies beneath the epithelium, and together with the epithelium and basement membrane constitutes the mucosa. As its Latin name indicates, it is a characteristic component of the mucosa, or the mucosa's "own special layer." Thus, the term mucosa or mucous membrane refers to the combination of the epithelium and the lamina propria. The connective tissue of the lamina propria is loose and rich in cells. The cells of the lamina propria are variable and can include fibroblasts, lymphocytes, plasma cells, macrophages, eosinophilic leukocytes, and mast cells. It provides support and nutrition to the epithelium, as well as the means to bind to the underl ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Basement Membrane
The basement membrane is a thin, pliable sheet-like type of extracellular matrix that provides cell and tissue support and acts as a platform for complex signalling. The basement membrane sits between Epithelium, epithelial tissues including mesothelium and endothelium, and the underlying connective tissue. Structure As seen with the electron microscope, the basement membrane is composed of two layers, the basal lamina and the reticular lamina. The underlying connective tissue attaches to the basal lamina with collagen VII anchoring fibrils and fibrillin microfibrils. The basal lamina layer can further be subdivided into two layers based on their visual appearance in electron microscopy. The lighter-colored layer closer to the epithelium is called the lamina lucida, while the denser-colored layer closer to the connective tissue is called the lamina densa. The Electron microscope, electron-dense lamina densa layer is about 30–70 nanometers thick and consists of an underlying ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Nasdaq
The Nasdaq Stock Market () (National Association of Securities Dealers Automated Quotations Stock Market) is an American stock exchange based in New York City. It is the most active stock trading venue in the US by volume, and ranked second on the list of stock exchanges by market capitalization of shares traded, behind the New York Stock Exchange. The exchange platform is owned by Nasdaq, Inc., which also owns the Nasdaq Nordic stock market network and several U.S.-based stock and options exchanges. History 1971–2000 "Nasdaq" was initially an acronym for the National Association of Securities Dealers Automated Quotations. It was founded in 1971 by the National Association of Securities Dealers (NASD), now known as the Financial Industry Regulatory Authority (FINRA). On February 8, 1971, the Nasdaq stock market began operations as the world's first electronic stock market. At first, it was merely a "quotation system" and did not provide a way to perform electronic trade ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Esquire (magazine)
''Esquire'' is an American men's magazine. Currently published in the United States by Hearst Communications, it also has more than 20 international editions. Founded in 1933, it flourished during the Great Depression and World War II under the guidance of founders Arnold Gingrich, David A. Smart and Henry L. Jackson while during the 1960s it pioneered the New Journalism movement. After a period of quick and drastic decline during the 1990s, the magazine revamped itself as a lifestyle-heavy publication under the direction of David Granger. History ''Esquire'' was first issued in October 1933 as an offshoot of trade magazine ''Apparel Arts'' (which later became '' Gentleman's Quarterly''; ''Esquire'' and ''GQ'' would share ownership for almost 45 years). The magazine was first headquartered in Chicago and then, in New York City. It was founded and edited by David A. Smart, Henry L. Jackson and Arnold Gingrich. Jackson died in the crash of United Airlines Flight 624 in 1948, ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Pig Bladder
Pig bladder (also pig's bladder) is the urinary bladder of a domestic pig, similar to the human urinary bladder. Today, this hollow organ has various applications in medicine, and in traditional cuisines and customs. Historically, the pig bladder had several additional uses, all based on its properties as a lightweight, stretchable container that could be filled and tied off. Traditional uses The pig bladder has several traditional ceremonial uses in Europe. It is traditional during the festival Fasching in Bad Aussee to brandish inflated pig bladders on sticks. Similarly, in Xinzo de Limia, Spain, inflated pig bladders are carried during Carnival. See also Clown society and Jester and Gigantes y cabezudos and Vejigante. In traditional Germanic communities a public Schlachtfest (of a pig) is announced by hanging the pig's inflated bladder in front of the host establishment. The bladder is used as a casing for several traditional food items, including the sausages known as v ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
New York Daily News
The New York ''Daily News'', officially titled the ''Daily News'', is an American newspaper based in Jersey City, NJ. It was founded in 1919 by Joseph Medill Patterson as the ''Illustrated Daily News''. It was the first U.S. daily printed in tabloid format. It reached its peak circulation in 1947, at 2.4 million copies a day. As of 2019 it was the eleventh-highest circulated newspaper in the United States. Today's ''Daily News'' is not connected to the earlier '' New York Daily News'', which shut down in 1906. The ''Daily News'' is owned by parent company Tribune Publishing. This company was acquired by Alden Global Capital, which operates its media properties through Digital First Media, in May 2021. After the Alden acquisition, alone among the newspapers acquired from Tribune Publishing, the ''Daily News'' property was spun off into a separate subsidiary called Daily News Enterprises. History ''Illustrated Daily News'' The ''Illustrated Daily News'' was founded by Patters ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
